Patents Assigned to Research
  • LILRB2 AND NOTCH-MEDIATED EXPANSION OF HEMATOPOIETIC PRECURSOR CELLS
    Publication number: 20190330593
    Abstract: The current disclosure describes methods of expanding precursor cells for hematopoietic transplantation in subjects. The methods culture precursor cells in media containing an immobilized high molecular weight LILRB2 agonist or an LILRB2 agonist in combination with a Notch agonist. The expanded cells can be used to treat a variety of hematopoietic disorders.
    Type: Application
    Filed: June 26, 2019
    Publication date: October 31, 2019
    Applicants: Fred Hutchinson Cancer Research Center, Board of Regents of the University of Texas System
    Inventors: Irwin D. Bernstein, Chengcheng Zhang, Mi Deng, Zhigang Lu, Junke Zheng
  • HIGH-CAPACITY MICRO-SUPERCAPACITOR, METHOD OF MANUFACTURING HIGH-CAPACITY MICRO-SUPERCAPACITOR, AND METHOD OF FORMING CURRENT COLLECTOR FOR MICRO-SUPERCAPACITOR
    Publication number: 20190333716
    Abstract: Disclosed herein is a method of manufacturing a micro-supercapacitor with an increased storage capacity of electrical energy. The method is a method of manufacturing a high-capacity micro-supercapacitor including an anode and a cathode separated from each other, which includes forming a pair of current collectors by discharging conductive ink on a substrate surface with a 3D printer, and forming an electrode consisting of an anode and a cathode by stacking an electrode constituting material in the form of a plurality of layers on each of the pair of current collectors using the 3D printer.
    Type: Application
    Filed: March 21, 2019
    Publication date: October 31, 2019
    Applicant: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Jung Joon YOO, Jong Huy KIM, YONG IL KIM, Jeong Hun BAEK, Ha Na YOON
  • METHODS AND COMPOSITIONS FOR DETERMINING, AND FOR MINIMIZING, THE LIKELIHOOD OF DEVELOPMENT OF ALLERGY IN INFANTS
    Publication number: 20190330686
    Abstract: The invention relates to allergic disease, to the development of allergic disease in infants, to determining the likelihood of development of allergic disease in infants and to minimizing the likelihood of development of allergic disease in infants.
    Type: Application
    Filed: December 22, 2017
    Publication date: October 31, 2019
    Applicant: MURDOCH CHILDREN?S RESEARCH INSTITUTE
    Inventors: Peter VUILLERMIN, Anne-Louise PONSONBY, Mimi TANG
  • METHOD FOR FORMING REDISTRIBUTION LAYER USING PHOTO-SINTERING
    Publication number: 20190335590
    Abstract: The present invention relates to a method for formation of a redistribution layer using photo-sintering and to the redistribution layer formed by the method. The method for forming a redistribution layer using photo-sintering includes printing, on a substrate, a liquid electrode pattern for a redistribution layer; coating a transparent polymer on the substrate and the pattern; photo-sintering the electrode pattern using photonic energy; and evaporating an organic substance contained in the liquid electrode pattern via the photo-sintering to remove the polymer on a top face of the electrode pattern to form a redistribution layer as the sintered electrode pattern.
    Type: Application
    Filed: April 18, 2019
    Publication date: October 31, 2019
    Applicant: Research & Business Foundation Sungkyunkwan University
    Inventors: SeungBoo JUNG, KwangHo JUNG, WooRam MYUNG, HakSan JEONG, BumGeun PARK, ChoongJae LEE, KyungDeuk MIN
  • METHOD FOR TRANSMISSION AND RECEPTION BASED ON HYBRID AUTOMATIC REPEAT REQUEST IN COMMUNICATION SYSTEM AND APPARATUS FOR THE SAME
    Publication number: 20190334661
    Abstract: Provided are a method and an apparatus for transmission and reception based on hybrid automatic repeat request in a communication system. A first communication node includes a coherent channel region (CCR) mapper configured to determine W representative soft bit values for each CCR on the basis of X original soft bit values of signals and determine a sign sequence of the X original soft bit values, and a CCR demapper configured to restore X soft bit values for each CCR using W representative soft bit values and a sign sequence. Since the CCR mapper compresses soft bits using channel coherency, a hybrid automatic repeat request (HARD) buffer size is reduced compared to that of an existing method. Therefore, performance of a communication system may be improved.
    Type: Application
    Filed: January 31, 2019
    Publication date: October 31, 2019
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Duk Hyun YOU
  • COMBINATION THERAPY FOR A STABLE AND LONG TERM ENGRAFTMENT
    Publication number: 20190328793
    Abstract: A method of treating a subject in need of a non-syngeneic cell or tissue graft is disclosed. The method comprising: (a) transplanting into a subject a dose of T cell depleted immature hematopoietic cells, wherein the T cell depleted immature hematopoietic cells comprise less than 5×105 CD3+ T cells per kilogram body weight of the subject, and wherein the dose comprises at least about 5×106 CD34+ cells per kilogram body weight of the subject; and subsequently (b) administering to the subject a therapeutically effective amount of cyclophosphamide, wherein the therapeutically effective amount comprises 25-200 mg per kilogram body weight, thereby treating the subject.
    Type: Application
    Filed: July 11, 2019
    Publication date: October 31, 2019
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Yair REISNER, Esther BACHAR-LUSTIG
  • Thermoforming Machine Having Toggle Differential Load Mechanism and Method
    Publication number: 20190329479
    Abstract: A thermoforming apparatus is provided having a frame, a pair of platens, and a platen drive assembly. The platens are carried by the frame on opposite sides of a sheet line each configured to carry a respective die. One platen has a proximal die surface adjacent the sheet line and a rear surface distal the sheet line. The platen drive assembly is interposed between the frame and the one platen and has at least one reciprocating kinematic linkage and a drive motor configured to reciprocate the one platen to and fro relative to another platen. The kinematic linkage has a plurality of links interconnected pivotally together with respective rotation joints and interposed between the frame and the one platen. An outboard-most rotation joint is provided proximate one end of the frame and an inboard-most rotation joint intermediate the rear surface and the proximal die surface. A method is also provided.
    Type: Application
    Filed: December 10, 2018
    Publication date: October 31, 2019
    Applicant: Irwin Research and Development, Inc.
    Inventors: Dale L. Vantrease, Jere F. Irwin
  • COMPOSITIONS AND METHODS TO MODIFY CELLS FOR THERAPEUTIC OBJECTIVES
    Publication number: 20190330373
    Abstract: The present disclosure provides compositions and methods that rapidly and selectively modify cells of the immune system to achieve therapeutic objectives. The methods can be practiced in vivo and any cell type that expresses a known marker can be targeted for a therapeutic objective.
    Type: Application
    Filed: July 12, 2019
    Publication date: October 31, 2019
    Applicant: Fred Hutchinson Cancer Research Center
    Inventor: Matthias Stephan
  • OLEFIN PRODUCTION METHOD USING CIRCULATING FLUIDIZED BED PROCESS
    Publication number: 20190330125
    Abstract: Disclosed is an olefin production method which includes: (a) providing the regenerated catalyst and the hydrocarbon including not less than 90 wt % of LPG into Riser of Fast Fluidization Regime, and dehydrogenating in the presence of an alumina type catalyst; (b) separating an effluent from the dehydrogenation reaction into the catalyst and propylene mixture; (c) stripping to remove the hydrocarbon compound included in the catalyst separated at stage (b); (d) mixing the catalyst stripped at stage (c) with the gas including oxygen, and continuously regenerating it; (e) recycling the catalyst regenerated at stage (d) to stage (a), and providing it again into Riser; and (f) producing propylene product by cooling, compressing and separating propylene mixture of the reaction product separated at stage (b).
    Type: Application
    Filed: May 1, 2018
    Publication date: October 31, 2019
    Applicants: SK GAS CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Deuk Soo PARK, Ung Gi HONG, Hyeongchan AHN, Won Choon CHOI, Yong Ki PARK
  • METHOD FOR MODIFYING THE THERAPEUTIC EFFECTS OF DRUGS
    Publication number: 20190329063
    Abstract: A method for modifying the effect of a drug by application of an activation protocol, comprising: administering a drug according to a treatment protocol; applying an activation protocol in a timed relationship to the administering, for differentially activation of at least one selected brain region; wherein the differentially activation allows the drug to selectively interact with the at least one selected brain region.
    Type: Application
    Filed: December 21, 2017
    Publication date: October 31, 2019
    Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Talma HENDLER, Gal RAZ, Roy Itzhak SAR-EL
  • CO-SPRAY DRYING OF CIPROFLOXACIN AND COLISTIN AND THE USES THEREOF
    Publication number: 20190328728
    Abstract: The present disclosure generally relates to a combination dry powder inhaler (DPI) formulation of Ciprofloxacin and Colistin through co-spray drying, particularly to a co-sprayed colistin and Ciprofloxacin dry powder inhaler for the treatment of various bacterial infections. Methods of use and composition matters are within the scope of this disclosure.
    Type: Application
    Filed: April 26, 2019
    Publication date: October 31, 2019
    Applicant: Purdue Research Foundation
    Inventors: Qi Zhou, Nivedita Shetty
  • APPARATUS AND METHOD OF CORRECTING 3D IMAGE DISTORTION
    Publication number: 20190332882
    Abstract: Disclosed is an apparatus and method of correcting 3D image distortion. A method of correcting 3D image distortion according to the present disclosure includes: receiving an input image that contains a predetermined first pattern; extracting a characteristic value related to the first pattern from the input image; and updating the input image on the basis of the extracted characteristic value.
    Type: Application
    Filed: April 15, 2019
    Publication date: October 31, 2019
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: Joon Soo KIM, Gwang Soon LEE
  • Thermoforming Platen Having Discrete Load Paths and Method
    Publication number: 20190329478
    Abstract: A thermoforming platen is provided having a tooling support plate and a plurality of discrete load paths. The tooling support plate has a top tooling surface, a bottom surface, and an outer periphery. The plurality of discrete load paths interconnect the bottom surface with one or more external load sources operative to distribute and centralize load deformation of the top plate from forming loads. The load paths are provided laterally inboard of the top tooling surface at one of a plurality of inboard locations to impart minimized tooling surface deformation along the top plate tooling surface. A method is also provided.
    Type: Application
    Filed: August 21, 2018
    Publication date: October 31, 2019
    Applicant: Irwin Research and Development, Inc.
    Inventors: Dale L. Vantrease, Jere F. Irwin
  • HERPES ZOSTER VACCINE COMPOSITION
    Publication number: 20190328868
    Abstract: The present invention relates to a herpes zoster vaccine composition, which comprises glycoprotein E of Varicella zoster virus, a glucopyranosyl lipid adjuvant, and a metabolic oil, and selectively increases a cell-mediated immune reaction without having disadvantages of attenuated live vaccines, thereby exhibit high safety and a high preventive effect against herpes zoster.
    Type: Application
    Filed: December 20, 2017
    Publication date: October 31, 2019
    Applicants: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, INFECTIOUS DISEASE RESEARCH INSTITUTE
    Inventors: Hyo Jung NAM, Eun Mi KIM, Duck Hyang SHIN, Steven G. REED, Kang Il YOO, Sung Jun HONG
  • ARYL ISONITRILES AS A NEW CLASS OF ANTIMICROBIAL COMPOUNDS
    Publication number: 20190330154
    Abstract: The present invention provides aryl isonitrile compounds that have antibacterial properties. More specifically, the aryl isonitrile compounds of the present invention are potent inhibitors of drug resistant strains of Staphylococcus aureus.
    Type: Application
    Filed: June 18, 2019
    Publication date: October 31, 2019
    Applicant: Purdue Research Foundation
    Inventors: Mohamed Seleem, Mingji Dai, Dexter Cameron Davis, Haroon Taj Mohammad
  • PURCHASE INFORMATION UTILIZATION SYSTEM, PURCHASE INFORMATION UTILIZATION METHOD, AND PROGRAM
    Publication number: 20190333077
    Abstract: The purpose of the present invention is to make it possible to provide related content to a terminal of a consumer who purchased a commercial product from any shop. A purchase information utilization system includes: a storage unit which stores a shop and content in association with each other; a receiving unit which receives information related to a receipt from a terminal of a consumer; an analysis unit which analyzes the information related to the receipt to identify a shop from which the consumer purchased a commercial product; and a content providing unit which extracts content related to the identified shop from the storage unit, and provides the extracted content to the terminal.
    Type: Application
    Filed: May 26, 2017
    Publication date: October 31, 2019
    Applicant: Research and Innovation Co., LTD.
    Inventor: Kuninobu Nakaoka
  • BIOLOGICAL MARKER AND METHODS
    Publication number: 20190328306
    Abstract: Systems, methods, and other techniques for monitoring, including non-invasive monitoring, of biological markers based on the interaction, temporal association, or coincidence of brain activity and periphery activity in a mammal are provided. Systems and methods for generating a behavioral state-independent representation of cardiac activity and for identifying cardiac events and/or brain-periphery, e.g., brain-cardiac, temporal associations useful as biomarkers of disease such as, e.g., neurologic disease, in a mammal are also provided.
    Type: Application
    Filed: April 26, 2019
    Publication date: October 31, 2019
    Applicant: The Penn State Research Foundation
    Inventors: Bruce J. Gluckman, Fatemeh Bahari, Steven J. Schiff
  • SYSTEMS FOR RECOMBINANT PROTEIN PRODUCTION
    Publication number: 20190330641
    Abstract: The present invention relates to a method of producing a recombinant polypeptide in a genetically modified host cell. A host cell and a vector for transforming such host cell is also provided.
    Type: Application
    Filed: June 16, 2017
    Publication date: October 31, 2019
    Applicant: NATIONAL HELLENIC RESEARCH FOUNDATION
    Inventors: Georgios SKRETAS, Dimitra GIALAMA
  • METHODS AND MATERIALS FOR TREATING CANCER
    Publication number: 20190328805
    Abstract: This document relates to methods and materials involved in treating cancer. For example, methods and materials for using one or more oncolytic viruses (e.g., one or more replicating oncolytic viruses) to treat cancer in a mammal (e.g., a human) identified as having a cancer likely to respond to oncolytic virotherapy are provided.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 31, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Mitesh J. Borad, Yumei Zhou, Amber C. Miller
  • TWO-PIECE VERTICAL CONTROL ARM BUSHING
    Publication number: 20190329618
    Abstract: A bushing, for use with a control arm, has first and second mating segments that can be mated and assembled to form a central portion to be received within a circular opening in the control arm and the central portion has an outer diameter corresponding to the diameter of the circular opening. Each segment includes a cap or head portion having a diameter dimensioned to abut against one of the surfaces of the control arm and has a central bore. A bushing sleeve has a length equal to a axial length of the assembled bushing and an outer diameter incrementally greater than the diameter of the central bore so that the sleeve can be press fit within the bore to immobilize the segments when they are in contact with the control arm and become resistant to separation.
    Type: Application
    Filed: April 30, 2019
    Publication date: October 31, 2019
    Applicant: RESEARCH & MANUFACTURING CORPORATION OF AMERICA
    Inventors: JOHN MUSCI, CARLOS GUERREIRO, JOE BERTA, ALAN LAMBERT