Abstract: Provided herein are methods for the diagnosis of human melanoma by assessing MITF, miR-211, TRPM1, and/or KCNMA1 and methods for the diagnosis of resistance to chemotherapeutic agents by assessing the regulatory pathways of PGC1?. Methods for treating melanoma, including drug-resistant melanoma, are also provided.

Abstract: There is provided an electrode for a lithium secondary battery. The electrode include a current collector; nanoparticles distributed on a surface of the current collector, each of the nanoparticles including a transition metal or an oxide of the transition metal; and an active material layer disposed on a surface of the current collector having the nanoparticles distributed thereon. This electrode may be employed as a negative electrode for the lithium second battery, to improve a capacity of the lithium second battery.

Abstract: A system for reception of electromagnetic waves in a spectrum in which interference with radio frequencies of other electronics devices occurs comprising a transmitter; at least one receiver configured to receive the received signal; each received signal organized into a digital vector; at least one memory portion configured to store a plurality of received signals in a vector form; the vectors being combined into a matrix, each vector of the matrix being a digital data record representing a received signal; at least one processor operatively connected to the at least one memory portion; the at least one processor configured to estimate that portion of the received signal attributable to noise; the at least one processor operating to jointly estimate a minimal number of distinctive noise patterns and minimize the simplicity of the data of interest; the at least processor operating to process the noise and data of interest separately.

Abstract: The present invention provides a method of characterizing a cancer by obtaining a sample from a subject suspected of having cancer; and determining whether a fibroblast growth factor receptor (FGFR) fusion is present in the sample, wherein the FGFR fusion comprises a FGFR locus, thereby characterizing the cancer based on the presence or absence of the FGFR fusion.

Abstract: Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropathic pain and nociceptive pain.

Abstract: Disclosed is a magnet terminal and a jumper wire including the magnet terminal. The magnet terminal comprises a magnet layer, a metallic structure placed on the magnet layer and configured to conduct an electric signal with the magnet layer, and a tube configure to partly cover an outer surface of the metallic structure, then providing a low-cost solderless magnet terminal which is available for a component or electric/electronic circuit attachable to a magnet.

Abstract: A full-range image detecting system including a planar light source, an image capturing device, a light sensing device, a processing unit and a measuring module is provided. The planar light source projects a photo image with periodical variations onto an object. The image capturing device captures a reflective photo image reflected from the object. The light sensing device detects the coordinates of at least three measuring points on the object for fitting a plane. The processing unit calculates a phase variation of the reflective photo image after phase shift, a relative altitude of the surface profile of the object according to the phase variation, and an absolute altitude of the surface profile of the object with respect to the plane to obtain an information of absolute coordinate. The measuring module detects the surface of the object according to the information of absolute coordinate of the object.

Abstract: An environmental sensitive electronic device package having side wall barrier structure may include a first package substrate, a second package substrate, a carrier substrate, an environmental sensitive electronic device, at least one side wall barrier structure and an adhesive. The second package substrate is located above the first package substrate. The carrier substrate is located above the first package substrate and between the first package substrate and the second package substrate. The environmental sensitive electronic device is located on the carrier substrate and between the carrier substrate and the second package substrate. The at least one side wall barrier structure is located between the first package substrate and the second package substrate. At least one portion of the at least one side wall barrier structure surrounds the environmental sensitive electronic device.

Abstract: Methods, systems, and computer program products are provided for analyzing a Global Navigation Satellite System (GNSS) receiver. The method includes receiving electronic diagnostic information from the GNSS receiver, the diagnostic information including observations at different times of signal strength of one or more satellites at each point in a visible sky. The method includes building a flat map of the visible sky including a track of the one or more satellites. The method includes calculating, for each point in the visible sky of the flat map, an aggregated signal strength of the one or more satellites over a predetermined interval. The method includes generating a heat map over the flat map of the visible sky and displaying a visualization of a flat heat map.

Abstract: A pulse photodynamic therapy (or pulse PDT) treatment of acne is described herein.

Abstract: A method for packaging and installing high performance insulation of a loose, granular, moisture-resistant nature, suitable for providing insulation in walls, ceilings, or other cavities in traditional buildings, cabinets or other structures requiring thermal or sound insulation, in a practical, easy to manage, modular fashion. The method provides for the packaging of insulation material to be contained in an air-tight but moisture permeable material that traps the particulates but not moisture vapor. The insulation material may also be blended with other materials to adjust the product's resistance to thermal or sound conductivity, cost, and in order to prevent leakage in the event of puncture.

Abstract: A system processes data signals consisting of sums of independent signal terms in order to generate one or more of those terms. The generated terms are computed using a set of reference signals to construct alternative support sets, whose images are computed on the reference signals. Computed images that are independent of the residue of the data signal minus the image are identified as independent signal terms, as are the residues. These initial signal terms are used to compute additional terms. Identified terms from different data signals are organized into independent slices, and slices whose terms are supported by sets of reference signals are associated with those supporting sets.

Abstract: An improved system and method for moving an object includes a first correlated magnetic structure associated with a first object and a second correlated magnetic structure associated with a second object. The first and second correlated magnetic structures are complementary coded to achieve a peak attractive tensile force and a peak shear force when their code modulos are aligned thereby enabling magnetic attachment of the two objects whereby movement of one object causes movement of the other object as if the two objects were one object. Applying an amount of torque to one correlated magnetic structures greater than a torque threshold causes misalignment and decorrelation of the code modulos enabling detachment of the two objects. The number, location, and coding of the correlated magnetic structures can be selected to achieve specific torque characteristics, tensile force characteristics, and shear force characteristics.

Abstract: The present invention is directed to RNA monomers comprising O-acetal levulinyl protecting groups at the 2? and/or the 5?-hydroxy functionalities of the ribose moiety. Said monomers may be incorporated into oligoribonucleotides or RNA polynucleotides. Furthermore, the invention is directed to methods for the synthesis of said RNA monomers, oligoribonucleotides and RNA polynucleotides, as well as methods for their deprotection and methods for the use of said compounds and compositions comprising said compounds. In particular, such compounds and compositions comprising them are used in methods for light-directed synthesis of RNA microarrays.

Abstract: A deposition apparatus for processing substrates includes a vacuum chamber including a processing zone in which a substrate may be processed. First and second gas sources are in fluid communication with the vacuum chamber. The first gas source is operable to supply a first gas into the vacuum chamber and the second gas source is operable to supply a second gas into the vacuum chamber. A showerhead assembly includes a face plate and back plate. The back plate includes a first gas inlet in fluid communication with the first gas source and a second gas inlet in fluid communication with the second gas source. The face plate includes a lower wall and an outer wall extending vertically upwardly from an outer periphery of the lower wall. The outer wall is sealed to an outer periphery of the back plate such that an inner plenum and an edge plenum are formed between the face plate and the back plate.

Abstract: There is provided a fiber including a cladding material that is disposed along a longitudinal-axis fiber length. A plurality of spherical particles are provided, separated from one another and disposed in a longitudinal line parallel to the longitudinal fiber axis. The particles are in a sequence with controlled periodic spacing between particles along at least a portion of the fiber length. Each spherical particle has a spherical particle material that is embedded within and elementally different than the fiber cladding material.

Abstract: Stents including a cylindrical body having a distal portion, a skirt having an apex coupled to the distal portion, and an extension mechanism adapted to expand the skirt are disclosed. Methods of inserting such stents are also disclosed.

Abstract: A human antibody which comprises a complementarity determining region of an H chain consisting of the amino acid sequence as shown in SEQ ID NOs: 1 to 3 and a complementarity determining region of an L chain consisting of the amino acid sequence as shown in SEQ ID NOs: 4 to 6. The human antibody of the present invention has the activity to specifically bind to transthyretin (TTR) with structural change and the activity to inhibit fibrillization of TTR and is a human antibody suitable for application to human body.

Abstract: Provided is a packet transmission apparatus including at least one user network interface (UNI) line card configured to receive traffic including a client signal, a fabric switch configured to perform switching on the traffic based on a unit of line card, a network-to-network interface working (NNI-W) line card configured to generate a multiprotocol label switching-transport profile (MPLS-TP) working tunnel to transmit the traffic transferred through the fabric switch, and a network-to-network interface protection (NNI-P) line card configured to generate a MPLS-TP protection tunnel to transmit the traffic transferred through the fabric switch when a fault occurs on a path of the NNI-W line card.

Abstract: The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to chimeric animals comprising reprogrammed somatic cells of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells.