Abstract: The present invention relates to a pharmaceutical composition for preventing and treating cancer which comprises the extracts of Artocarpus altilis fruits, leaves, or stems, or the fractions thereof as active ingredients. The extracts of Artocarpus altilis fruits, leaves, or stems, or the fractions thereof, according to the present invention, suppress the activity of signal transducer and activator of transcription3 (STAT3) which plays an important role in the growth of a cancer cell line and in the immune function of the human body, and can thus be effectively used in the prevention and treatment of cancers such as colorectal cancer, stomach cancer, prostate cancer, breast cancer, renal cancer, liver cancer, brain tumor, lung cancer, uterine cancer, colorectal cancer, bladder cancer, or pancreatic cancer.
Type:
Grant
Filed:
July 26, 2013
Date of Patent:
November 8, 2016
Assignee:
Korea Research Institute of Bioscience and Biotechnology
Inventors:
Byoung-Mog Kwon, Dong Cho Han, Joongku Lee, Yoon-jeong Jeon, Sang Ho Choi
Abstract: PBI-based MEAs for high temperature Polymer Electrolyte Membrane Fuel Cell (PEMFC) were prepared by direct hot pressing of catalyst layer on Teflon sheets on to both sides of phosphoric acid doped PBI membrane (decal transfer). These MEAs show two times higher performance compared to the MEAs prepared by normal brush coating method on GDL at an operating temperature of 160° C.
Type:
Grant
Filed:
March 29, 2012
Date of Patent:
November 8, 2016
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Abstract: Thermally stable piezoelectric polymer foams (ferroelectrets) with high piezoelectric activity for sensing and actuation. The invention further includes a method of fabricating such foams in an environmentally friendly manner.
Type:
Grant
Filed:
August 17, 2015
Date of Patent:
November 8, 2016
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: Disclosed is a hybrid dc-dc converter. The hybrid dc-dc converter includes: a pair of transformers configured to magnetically couple a primary side to a secondary side, a full-bridge converter including four switches constituting a full-bridge inverter circuit and a first transformer, and an LLC resonant converter including a resonant inductor, a resonant capacitor, and a second transformer, which constitute an LLC resonant circuit, wherein an output of the full-bridge converter and an output of the LLC resonant converter are connected to each other in series at the secondary side.
Abstract: A method of inspecting a structure is disclosed. The method generally comprises selecting a search region of a dispersion curve of the structure corresponding to one or more inspection parameters. The search region comprises at least one guided wave mode activation point not located on the dispersion curve. The method further comprises activating, using an inspection system comprising at least one transducer, a plurality of activation points located within the search region of the dispersion curve and identifying an optimal activation point for the one or more inspection parameters. The optimal activation point comprises at least one of the plurality of activation points producing an optimal response for the one or more inspection parameters.
Abstract: Apparatuses and methods are disclosed for determining whether a structure of bonded layers includes locations where the layers are weakly bonded. Embodiments include evaluating the frequency response of the structure in response to vibrational inputs. Alternate embodiments include evaluating the non-linear response of the structure using a modal analysis. Further embodiments include obtaining the vibrational information with an accelerometer contacting the structure, while additional embodiments include exciting the structure with an impact force, which may be applied at multiple locations on the structure's surface. Still further embodiments include performing a MAC, COMAC, and/or FRF analysis. Still other embodiments include varying the amplitude of the input vibration. Additional embodiments locate the areas of weakened bonding. Still other embodiments include methods and apparatuses for simulating a laminated structure with defective bonding, such as kiss bonding.
Type:
Grant
Filed:
March 15, 2012
Date of Patent:
November 8, 2016
Assignee:
Purdue Research Foundation
Inventors:
Douglas E. Adams, Nathan D. Sharp, Ronald Sterkenburg
Abstract: A device for accessing web services uses a service interface and a conversion and interpretation unit to implement a method which simplifies the access interface of wave services. The service interface includes an upload element, a download element and a command element. With the conversion and interpretation unit, the data and the command of web pages are converted and interpreted as the contents of the three elements. The contents are converted into web page documents and forwarded to a network platform for further processing associated tasks. The presentation on the service interface may replace the browsers and achieve the function of supporting the participation-typed service. It simplifies the complexity on the network access interface, and can access different services provided by different servers.
Type:
Grant
Filed:
June 8, 2007
Date of Patent:
November 8, 2016
Assignee:
Industrial Technology Research Institute
Inventors:
Tzu-Ming Lin, Chien-Ming Chou, Ya Ping Jeng
Abstract: The electronic device is provided with an automatic leak detection means, notably for a gas leak, in the case of the device. The automatic leak detection means includes a pressure sensor, a temperature sensor and a calculation unit connected to the pressure sensor and to the temperature sensor. The calculation unit, which is a microcontroller, the pressure sensor and the temperature sensor are arranged inside the case. In operation, the microcontroller checks, based on measurements performed by the pressure sensor and the temperature sensor over time, whether the variation in pressure in the case is within a defined margin proportional to the variation in temperature to determine whether or not the case has a sufficient degree of sealing.
Type:
Grant
Filed:
January 29, 2014
Date of Patent:
November 8, 2016
Assignee:
The Swatch Group Research and Development Ltd
Inventors:
Michel Willemin, Jean-Claude Martin, Christophe Germiquet
Abstract: A low density parity check (LDPC) encoder, an LDPC decoder, and an LDPC encoding method are disclosed. The LDPC encoder includes first memory, second memory, and a processor. The first memory stores an LDPC codeword having a length of 16200 and a code rate of 2/15. The second memory is initialized to 0. The processor generates the LDPC codeword corresponding to information bits by performing accumulation with respect to the second memory using a sequence corresponding to a parity check matrix (PCM).
Type:
Grant
Filed:
February 8, 2016
Date of Patent:
November 8, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Sung-Ik Park, Heung-Mook Kim, Sun-Hyoung Kwon, Nam-Ho Hur
Abstract: A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co-administered with a lipophilic microphase-forming material to an in vivo use environment.
Type:
Grant
Filed:
October 26, 2007
Date of Patent:
November 8, 2016
Assignee:
Bend Research, Inc.
Inventors:
Michael E. Perlman, Ravi M. Shanker, Walter C. Babcock, Dwayne Thomas Friesen, Mark D. Rabenstein, Dan Tod Smithey
Abstract: Provided herein are peptide combinations comprising a GIP agonist peptide and a glucagon antagonist peptide. In some embodiments, the peptide combination is provided as a composition, e.g., a pharmaceutical composition, while in other embodiments, the peptide combination is provided as a kit. In yet other embodiments, the peptide combination is provided as a conjugate, e.g., a fusion peptide, a heterodimer. In specific aspects, the GIP agonist peptide is an analog of native human glucagon. In specific aspects, the glucagon antagonist peptide is an analog of native human glucagon. In some embodiments, the GIP agonist peptide is covalently attached to the glucagon antagonist peptide via a linker. Method of treating a disease, e.g., a metabolic disorder, such as diabetes and obesity, comprising administering the peptide compositions described herein are further provided.
Type:
Grant
Filed:
September 13, 2013
Date of Patent:
November 8, 2016
Assignee:
Indiana University Research and Technology Corporation
Abstract: A method for performing high speed mode detection of a carrier frequency offset (CFO) includes receiving a Zadoff-Chu signal at a wireless device, and determining a plurality of correlation peaks based on a correlation of the signal with one or more known Zadoff-Chu sequences. The method includes determining a carrier frequency offset (CFO) associated with the signal based on a phases associated with the plurality of correlation peaks and a coarse CFO estimate. The coarse CFO estimate may be determined based on a squared power ratio of particular pairs of the plurality of correlation peaks and the phases may be used to remove ambiguity associated with the coarse CFO estimate.
Type:
Grant
Filed:
February 4, 2015
Date of Patent:
November 8, 2016
Assignee:
Hong Kong Applied Science and Technology Research Institute Co., Ltd.
Inventors:
Yuxian Zhang, Honglei Zhang, Victor Kwan, Eric Tsang
Abstract: A system to fabricate hierarchical graded materials includes a reservoir to contain a material to be deposited, a print head connected to the reservoir to allow the print head to receive the material to be deposited, the print head having a mixing section, and an actuator connected to the print head, the actuator configured to actuate the print head in six axes of motion.
Type:
Grant
Filed:
December 19, 2014
Date of Patent:
November 8, 2016
Assignee:
PALO ALTO RESEARCH CENTER INCORPORATED
Inventors:
John Steven Paschkewitz, Gabriel Iftime, Victor Alfred Beck, David Mathew Johnson
Abstract: The present invention relate to compounds of general formula A. The invention also provides the synthesis of 3,4,5-trimethoxystyrylarylaminopropenones useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof. wherein: R=H, OMe, Cl, F, OH, Me X=aryl, heteroaryl.
Type:
Grant
Filed:
April 17, 2015
Date of Patent:
November 8, 2016
Assignee:
Council of Scientific and Industrial Research
Abstract: An optical encoder includes a light emitting module, a positioning device and a light separating structure. The light emitting module emits a light beam illuminating an illumination area of the positioning device. The positioning device includes light penetrating areas arranged in a dislocation manner. The light penetrating areas sequentially move into the illumination area. The light separating structure is disposed in the path of the light beam. The positioning device is disposed between the light emitting module and the light separating structure. When part of the light beam penetrates one of these light penetrating areas and is transmitted to the light separating structure, the light separating structure transmits the light to a sensing area and forms at least one first positioning optical pattern. The distance between two first positioning optical patterns formed by two adjacent light penetrating areas is greater than the pitch between the two adjacent light penetrating areas.
Type:
Grant
Filed:
February 13, 2015
Date of Patent:
November 8, 2016
Assignee:
Industrial Technology Research Institute
Abstract: The invention relates to lubricants for magnetic recording media, and in particular, to such lubricants containing cyclotriphosphazene. Methods for preparing the lubricants are also disclosed.
Type:
Grant
Filed:
August 7, 2013
Date of Patent:
November 8, 2016
Assignee:
Agency for Science, Technology and Research
Inventors:
Jianwei Xu, Rong Ji, Xiaobai Wang, Yan Xuan Angeline Tan, Ching Mui Cho, Chaobin He, Huiqing Xie, Wen Huei Jack Tsai
Abstract: There is disclosed a device for improving flow of a viscous fluid in a fluid transport conduit, the device comprising: a porous conduit having a passage through which the viscous fluid may pass between upstream and downstream sections of the fluid transport conduit; and a casing member having a wall which extends around the porous conduit, the device being configured such that, when it is in situ, a fluid transfer chamber having at least one fluid inlet is defined between the casing member wall and porous conduit, whereby lubricating fluid may pass under pressure through the inlet(s) into the fluid transfer chamber and through the porous conduit into the passage to lubricate the flow.
Type:
Grant
Filed:
June 26, 2014
Date of Patent:
November 8, 2016
Assignee:
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
Inventors:
Jie Wu, Lachlan Graham, John Farrow, Bon Nguyen
Abstract: A low density parity check (LDPC) encoder, an LDPC decoder, and an LDPC encoding method are disclosed. The LDPC encoder includes first memory, second memory, and a processor. The first memory stores an LDPC codeword having a length of 16200 and a code rate of 2/15. The second memory is initialized to 0. The processor generates the LDPC codeword corresponding to information bits by performing accumulation with respect to the second memory using a sequence corresponding to a parity check matrix (PCM).
Type:
Grant
Filed:
September 25, 2014
Date of Patent:
November 8, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Sung-Ik Park, Heung-Mook Kim, Sun-Hyoung Kwon, Nam-Ho Hur
Abstract: An electronic comparison system includes input stages that successively provide bits of code words. One-shots connected to respective stages successively provide a first bit value until receiving a bit having a non-preferred value concurrently with an enable signal, and then provide a second, different bit value. An enable circuit provides the enable signal if at least one of the one-shots is providing the first bit value. A neural network system includes a crossbar with row and column electrodes and resistive memory elements at their intersections. A writing circuit stores weights in the elements. A signal source applies signals to the row electrodes. Comparators compare signals on the column electrodes to corresponding references using domain-wall neurons and store bit values in CMOS latches by comparison with a threshold.