Abstract: Provided herein are compositions, methods, systems associated with propagation and fermentation, and co-products of biochemical production processes, for example, a DCO co-product resulting from converting oil containing grains into bio chemicals via fermentation in the presence of endogenous esterase. The DCO resulting from the processes exhibits lower metal ion content relative to a DCO obtained in the absence of endogenous fermentation with an esterase such as a lipase. The DCO is useful as a feedstock for the production of renewable diesel.
Type:
Grant
Filed:
August 5, 2021
Date of Patent:
May 21, 2024
Assignee:
POET Research, Inc.
Inventors:
Andrew J. Manning, Alex T. McCurdy, Steven T. Bly
Abstract: This disclosure provides compositions and methods for altering or changing the tissue tropism, e.g., liver tropism, of adeno-associated viruses (AAV).
Type:
Grant
Filed:
May 10, 2019
Date of Patent:
May 21, 2024
Assignees:
Massachusetts Eye and Ear Infirmary, The Schepens Eye Research Institute, Inc.
Inventors:
Luk H. Vandenberghe, Pauline Schmit, Christopher Tipper, Carmen Unzu, Eric Zinn
Abstract: Fire protection sprinkler assemblies and methods thereof having thermally responsive glass bulb trigger arrangements for suppression mode fast response fire protection in which the glass bulb trigger arrangements provide a consistent thermal response.
Type:
Grant
Filed:
November 8, 2022
Date of Patent:
May 21, 2024
Assignee:
Minimax Viking Research & Development GmbH
Abstract: The present invention is directed at the synthesis and characterization of recrystallized HI-6 dimethylsulfate (DMS). The method can comprise dissolving HI-6 DMS in an alkyl-based glycol and adding an antisolvent to recrystallize HI-6 DMS or dissolving HI-6 DMS in methanol and adding dimethoxy ethane or dimethyl formamide as the antisolvent to recrystallize HI-6 DMS. The recrystallized HI-6 DMS indicates a resistance to moisture absorption and/or a DSC melting point onset (MP Onset) at least at or above 160.0° C.
Abstract: The present invention solves difficulties in constructing a dialogue corpus, ensures the accuracy of a system utterance, and evaluates a user utterance in a dialogue technology for language learning and a knowledge-grounded dialogue technology, in which a system and method is capable of helping a learner in language learning by constructing a language learning dialogue corpus using passages and exercises commonly used in language education and learning sites, training a dialogue model and a dialogue evaluation model with the language learning dialogue corpus, and allowing a user and a system to have a dialogue on the basis of a given passage. It is expected that it will be possible to implement a dialogue system for language learning that is capable of performing evaluation and easily expanding a domain (expansion of learning content).
Type:
Grant
Filed:
October 19, 2021
Date of Patent:
May 21, 2024
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Human pluripotent stem cells (hPSCs) are promising cell source to produce therapeutic endocrine cells for diabetes treatment. A gel solution made by decellularized tissue-specific extracellular matrix (dpECM) significantly promotes three-dimensional (3D) islet-like organogenesis during induced hPSC differentiation into endocrine lineages. Islet organoids are self-organized even in a two-dimensional (2D) culture mode. Cells derived from hPSCs differentiated on such ECM coated substrates exhibit similar cellular composition to native pancreatic islets. These cells express islet signature markers insulin, PDX-1, C-peptide, MafA, glucagon, somatostatin, and pancreatic polypeptide, and secrete more insulin in response to glucose level compared to a traditional matrix substrate (Matrigel). The dpECM facilitates generating more C-peptide+/glucagon? cells rather than C-peptide+/glucagon+ cells. Remarkably, dpECM also facilitated intra-organoid vascularity by generating endothelial cells and pericytes.
Type:
Grant
Filed:
September 7, 2020
Date of Patent:
May 21, 2024
Assignee:
The Research Foundation for The Sate University of New York
Abstract: In one aspect, compositions and wound dressings are described herein. In some embodiments, a composition or wound dressing described herein comprises a mesh formed from a plurality of biodegradable polymer fibers; a first active agent dispersed in the biodegradable polymer fibers; a plurality of biodegradable polymer particles disposed in the mesh; and a second active agent dispersed in the biodegradable polymer particles. The particles can be disposed within the interiors of the fibers of the mesh or between the fibers of the mesh. In another aspect, a composition or wound dressing described herein comprises a first perforated mesh formed from a first plurality of biodegradable polymer fibers; and a second perforated mesh formed from a second plurality of biodegradable polymer fibers, wherein the second perforated mesh is disposed on the first perforated mesh in a stacked configuration and the first and second perforated meshes have different degrees of perforation.
Type:
Grant
Filed:
October 12, 2021
Date of Patent:
May 21, 2024
Assignees:
THE PENN STATE RESEARCH FOUNDATION, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Abstract: Antimicrobial diferulates, compositions containing same, and uses of same for inhibiting growth of microorganisms. The antimicrobial diferulates can be used alone or in combination with other antimicrobial agents to inhibit growth of microorganisms such as fungi, oomycetes, and other microorganisms having a glucan-containing cell wall. The antimicrobial diferulates can be included in pharmaceutical compositions for treatment of animals or included in agricultural compositions for treatment of plants, crops, and soils.
Type:
Grant
Filed:
August 27, 2021
Date of Patent:
May 21, 2024
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Jeff S. Piotrowski, Fachuang Lu, Mehdi Kabbage, John Ralph, Robert C. Landick
Abstract: The present disclosure provides an instruction execution method, device, and electronic equipment. In the instruction execution method described above, after obtaining an exceptional signal generated by a neural network processor during an operation, the electronic equipment determines an exception processing instruction corresponding to the exceptional signal according to the exceptional signal, then it determines a first instruction queue needed to be executed by the neural network processor, and then it generates a second instruction queue based on the exception processing instruction and the first instruction queue, and finally it controls the neural network processor to execute the second instruction queue, so that errors encountered by the neural network processor can be timely processed, thereby shortening the error processing delay and improving the data processing efficiency of the hardware system in the electronic equipment.
Type:
Grant
Filed:
April 7, 2021
Date of Patent:
May 21, 2024
Assignee:
BEIJING HORIZON ROBOTICS TECHNOLOGY RESEARCH AND DEVELOPMENT CO., LTD.
Abstract: An apparatus for controlling object tracking and a method therefor are provided. The apparatus includes an object detector configured to detect an object in an image, an object tracker configured to track the object, a learning device configured to learn whether to enable the object detector based on features of the object and tracking results of the object tracker, and a controller configured to determine whether to enable the object detector by interworking with the learning device.
Type:
Grant
Filed:
May 5, 2021
Date of Patent:
May 21, 2024
Assignees:
Hyundai Motor Company, Kia Corporation, INCHEON NATIONAL UNIVERSITY RESEARCH & BUSINESS FOUNDATION
Inventors:
Young Hyun Kim, Seung Hwan Bae, Seong Ho Lee
Abstract: A combined platform for testing fireproof materials for cables includes a main frame for providing operating space; an air circulation system including a fresh air supply unit for supplying fresh air into the operating space and an exhaust gas treatment unit for treating the gas in the operating space under set conditions; an open flame system for providing an open flame for testing cables; a water circulation system for supplying water at least to the exhaust gas treatment unit and the operating space; and a control system for collecting at least the temperature and gas concentration in the operating space, and performing process control based on the collected results. The actual working conditions of scenarios such as fire-resistant cable tunnels and fire-resistant cable trenches can be simulated, and multiple tests such as combustion performance test and physical and chemical performance test can be carried out under various working conditions.
Type:
Grant
Filed:
May 19, 2021
Date of Patent:
May 21, 2024
Assignee:
STATE GRID JIANGSU ELECTRIC POWER COMPANY RESEARCH INSTITUTE
Inventors:
Chenying Li, Jie Chen, Xiao Tan, Yijun Fei, Wei Zhang, Jingying Cao, Yang Liu, Qiang Wu, Jinggang Yang, Qiang Huang, Rong Sun, Jian Liu, Hongze Li, Liguo Liu
Abstract: A method of transforming a degree of freedom (DoF) in a multiple sensorial media (mulsemedia) system includes detecting, by a motion detector, a motion of an object to which motion effects are to be provided; calculating, by a motion proxy calculator, a motion proxy corresponding to the motion of the object; and transforming, by a transformer, the motion proxy into a motion command implementable within a motion range of a motion platform.
Type:
Grant
Filed:
March 25, 2022
Date of Patent:
May 21, 2024
Assignee:
POSTECH Research and Business Development Foundation
Inventors:
Seung Moon Choi, Gyeo Re Yun, Sang Yoon Han
Abstract: Methods of treating or reducing risk of aneurysm, reducing cardiovascular risk, reducing serum cholesterol, reducing serum triglycerides, and/or reducing atherosclerotic plague in a subject involve administering to the subject an effective amount of a 5HT3R antagonist.
Type:
Grant
Filed:
May 2, 2022
Date of Patent:
May 21, 2024
Assignee:
University of Kentucky Research Foundation
Inventors:
Lisa Cassis, Sean Thatcher, Yasir Alsiraj, Mark Ensor, Eric Blalock
Abstract: Disclosed herein are an apparatus and method for providing a remote work environment. The apparatus includes one or more processors and executable memory for storing at least one program executed by the one or more processors. The at least one program performs Virtual Private Network (VPN) authentication in response to a request for remote access to a work network from a user terminal, performs user authentication in order to connect the user terminal that succeeds in VPN authentication to the work network, decrypts the encrypted user data area of the user terminal that is connected to the work network, and provides the remote work environment to the user terminal based on the user data area through the work network.
Type:
Grant
Filed:
September 7, 2021
Date of Patent:
May 21, 2024
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Gak-Soo Lim, Sung-Jin Kim, Jung-Hwan Kang, Seung-Hun Han, Byung-Joon Kim
Abstract: A lens is positioned to be received by a lens holder. The lens includes a first electrical trace and the lens holder includes a second electrical trace. The first and second electrical traces form electrodes of a sense capacitor. A capacitance of the sense capacitor is sensed. From the sensed capacitance, a determination is made as to whether the lens is present and properly positioned in the lens holder.
Abstract: A method of treating a malignant disease involving T cell exhaustion in a subject, with the proviso that said malignant disease is not a B cell malignancy, is disclosed. The method comprising administering to the subject a therapeutically effective amount of an agent capable of decreasing an activity or expression of CD84, thereby treating the malignant disease involving the T cell exhaustion. Also disclosed is a method of treating an autoimmune or inflammatory disease in a subject, the method comprising administering to a subject a therapeutically effective amount of an agent capable of decreasing an activity or expression of CD84. A method comprising administering to the subject a therapeutically effective amount of an agent capable of decreasing an activity or expression of SLAMF1, with the proviso that said agent is not an agent capable of decreasing an activity or expression of CD84, is also disclosed.
Type:
Grant
Filed:
November 5, 2020
Date of Patent:
May 21, 2024
Assignee:
Yeda Research and Development Co. Ltd.
Inventors:
Idit Shachar, Hadas Lewinsky, Lihi Radomir, Anna Wiener
Abstract: A horological component including a substrate and at least one first decoration component including at least one first photoluminescent material configured to procure a phosphorescent appearance. The horological component includes a second decoration component including at least one second material, the second material being metallic and configured to procure a metallic appearance, or variochromic and configured to procure a color that varies under the effect of a stimulus, the first decoration component and the second decoration component being arranged relative to one another on the substrate to form a decoration having a metallic appearance or a color that varies under the effect of a stimulus when the horological component is exposed to light and a phosphorescent appearance when the horological component is in the dark. A timepiece can include such a horological component.
Type:
Grant
Filed:
July 27, 2020
Date of Patent:
May 21, 2024
Assignee:
The Swatch Group Research and Development Ltd
Inventors:
Nicolas Francois, Agnes Marlot Doerr, Carole Govaerts
Abstract: A transformer-based amplifier, an operating method thereof, and devices including the same are disclosed. A millimeter wave amplifier includes a first transformer positioned on an input side of the millimeter wave amplifier, a second transformer positioned on an output side of the millimeter wave amplifier, and one or more of amplification stages positioned between the first transformer and the second transformer.
Type:
Grant
Filed:
January 17, 2022
Date of Patent:
May 21, 2024
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
Type:
Grant
Filed:
December 14, 2020
Date of Patent:
May 21, 2024
Assignees:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, EXACT SCIENCES CORPORATION
Inventors:
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Abstract: The present invention relates to a composition for inducing dedifferentiation form somatic cells to induced pluripotent stem cells (iPSs) and method of inducing dedifferentiation using same, wherein the composition for inducing dedifferentiation and the method of inducing dedifferentiation increases the efficiency of dedifferentiation from somatic cells to iPSs by stimulating CXC chemokine receptor 2 (CXCR2), which is a receptor on human somatic cells, and thus may be effectively used for inducing the dedifferentiation to iPSs.
Type:
Grant
Filed:
April 2, 2019
Date of Patent:
May 21, 2024
Assignee:
Korea University Research and Business Foundation