Abstract: There is provided a method of diagnosing a medical state associated with a neuro-psychiatric disorder in a subject, comprising: receiving EEG datasets from EEG electrodes monitoring a head of the subject, computing events for the EEG datasets, clustering the events into clusters, computing a p-adic representation of the clusters, extracting a p-adic topology from the p-adic representation of the clusters, computing a personal universal dendrogramic holographic signature (PUDHS) of the p-acid topology relative to a personalized threshold that separates between a relative large distance between events and a relatively small distance between events, the PUDHS denoting number of events below the personalized threshold, and diagnosing the medical state associated with the neuro-psychiatric disorder according to the PUDHS relative to a medical threshold that separates between presence of the medical state and non-presence of the medical state.
Type:
Application
Filed:
March 10, 2023
Publication date:
April 3, 2025
Applicants:
Ramot at Tel-Aviv University Ltd., Mor Research Applications Ltd.
Inventors:
Oded SHOR, Felix BENNINGER, Andrei KHRENNIKOV
Abstract: Examples are disclosed herein relating to detecting a change in a substrate. A system can include a transducer that can be frequency matched to a substrate and to provide an electrical signal that can characterize a reflected sound wave by the substrate. The system can include an acoustic wave analysis system to detect a change in a physical characteristic of the substrate.
Type:
Application
Filed:
October 2, 2023
Publication date:
April 3, 2025
Applicants:
XEROX CORPORATION, NATIONAL RESEARCH COUNCIL OF CANADA
Inventors:
Sarah J. VELLA, Silvio E. KRÜGER, Edward G. ZWARTZ, Alexandros VASILEIOU, Johann JUNGINGER, Hamed O. TABRIZI
Abstract: An emulsion spectrum fluid filter capable of controlling light wavelength absorption includes a transparent channel formed as a tube of a 90 degrees-rotated U shape, and an emulsion received in the transparent channel, wherein the emulsion may include dispersed oil and surfactant. Further, a method for preparing the emulsion is disclosed.
Type:
Application
Filed:
June 21, 2022
Publication date:
April 3, 2025
Applicant:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Abstract: The present invention relates to a method for producing an adipose model through environmental control and an adipose model created using same, the method comprising the steps of: providing a first bioink, which is cell-unfriendly; creating a bath suspension with a predetermined volume by using the first bioink; providing a second bioink comprising preadipocytes; 3Dprinting the second bioink in the bath suspension so as to produce an adipose model; and culturing the bath suspension in which the adipose model is disposed. The method for producing an adipose model through environmental control and the adipose model created using same, according to the present disclosure, form environments for a 3D-printed adipose model, and limit the proliferation area of adipose cells and induce the differentiation thereof, and thus can maximize similarity with actual adipose tissues.
Type:
Application
Filed:
January 4, 2023
Publication date:
April 3, 2025
Applicants:
POSTECH Research and Business Development Foundation, PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
Inventors:
Dong-Woo CHO, Byoung Soo KIM, Won-Woo CHO, Min Jun AHN
Abstract: Provided is a method for predicting drug efficacy of lung cancer, including providing a biological sample of a subject with lung cancer; analyzing an expression level of Leucine Zipper Down-regulated in Cancer 1; and predicting the drug efficacy based on the expression level of the Leucine Zipper Down-regulated in Cancer 1. Also provided is kit for predicting drug efficacy of lung cancer in a subject in need thereof, including an antibody against Leucine Zipper Down-regulated in Cancer 1 or a Leucine Zipper Down-regulated in Cancer 1-specific primer. Further provided is a method for treating lung cancer, including enhancing expression of Leucine Zipper Down-regulated in Cancer 1 encoded by Ldoc1 gene in a subject in need thereof.
Type:
Application
Filed:
September 26, 2024
Publication date:
April 3, 2025
Applicants:
National Health Research Institutes, National Taiwan University Hospital Hsin-Chu Branch
Abstract: Aqueous ocular topical pharmaceutical formulations are provided that deliver an effective amount of (lev)cromakalim or a pharmaceutically acceptable salt thereof to treat an anterior or a posterior ocular disorder that responds to (lev)cromakalim, including glaucoma.
Type:
Application
Filed:
October 4, 2024
Publication date:
April 3, 2025
Applicants:
QLARIS BIO, INC., MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventors:
Thurein M. Htoo, Michael P. Fautsch, Gary Allred, Ralph Casale, Barbara M. Wirostko
Abstract: A system includes a processor and a memory communicably coupled to the processor and storing machine-readable instructions that, when executed by the processor, cause the processor to calculate joint probability functions for electronic chemical potential and oxidation states for ion types of a solid inorganic material, calculate a likelihood score for a plurality of oxidation state sets for the individual ion types in the solid inorganic material, and select one set of oxidation state from the plurality of oxidation state sets for the individual ion types as a function of the likelihood score. In some variations, the joint probability functions are calculated with a trained machine learning module.
Type:
Application
Filed:
April 30, 2024
Publication date:
April 3, 2025
Applicants:
Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
Abstract: The present invention relates to a lithium compound, a nickel-based cathode active material, a method for preparing lithium oxide, a method for preparing a nickel-based cathode active material, and a secondary battery using same. The lithium compound includes primary particles of Li2O having an average particle diameter (D50) of less than or equal to 5 ?m; and secondary particles composed of the primary particles.
Type:
Application
Filed:
December 11, 2024
Publication date:
April 3, 2025
Applicants:
POSCO CO., LTD, RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE & TECHNOLOGY
Inventors:
Jae Myung Lee, Jun-Kyu Ahn, Sang Won Kim, Heok Yang
Abstract: Systems and methods are provided for determining vehicle configurations. The system can receive simulation data or actual driving data of a driving track corresponding to a driver and associate the simulation data or actual driving data with one or more driving parameters. A driver style can be determined based on the one or more driving parameters. A vehicle configuration can be determined for a vehicle of the driver based on the determined driver style. The system can display one or more vehicle settings associated with the vehicle configuration on a user interface.
Type:
Application
Filed:
September 28, 2023
Publication date:
April 3, 2025
Applicants:
TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
Inventors:
John K. Subosits, Yun Jung Lee, Shawn Manuel, Avinash Balachandran
Abstract: Dry development of resists can be useful, for example, to form a patterning mask in the context of high-resolution patterning. Dry development may be advantageously accomplished by a method of processing a semiconductor substrate including providing in a process chamber a photopatterned resist on a substrate layer on a semiconductor substrate, and dry developing the photopatterned resist by removing either an exposed portion or an unexposed portion of the resist by a dry development process comprising exposure to a chemical compound to form a resist mask. The resist may be an EUV-sensitive organo-metal oxide or organo-metal-containing thin film EUV resist.
Type:
Application
Filed:
December 13, 2024
Publication date:
April 3, 2025
Applicant:
Lam Research Corporation
Inventors:
Boris Volosskiy, Timothy William Weidman, Samantha SiamHwa Tan, Chenghao Wu, Kevin Li Gu
Abstract: The present disclosure, at least in part, relates to compositions (e.g., engineered nucleic acids and engineered proteins) and methods for increasing gene expression. The engineered proteins include RNA-binding proteins (e.g., RNA-binding proteins that comprise a Interleukin Enhancer Binding Factor 3 (ILF3) sequence, a Cas sequence, or a combination thereof). In some aspects, the disclosure provides methods of identifying engineered nucleic acids that are shorter in length than a gene of interest to induce expression of the gene of interest and also provides RNA-binding proteins for inducing gene expression.
Type:
Application
Filed:
September 27, 2024
Publication date:
April 3, 2025
Applicant:
Whitehead Institute for Biomedical Research
Inventors:
Jonathan Weissman, Mohamed El-Brolosy, André Fischer, Atharv Vivek Oak
Abstract: Provided is a flying apparatus capable of effectively cooling a constituent device. A flying apparatus 10 comprises: an airframe base 14; a power supply unit; an arm 11 which extends from the airframe base 14 toward a periphery; a rotor 12 which is disposed on an end portion side of the arm 11; a motor 17 which rotationally drives the rotor 12; and a power converting unit 19 which converts electric power supplied from the power supply unit to the motor 17. The power converting unit 19 is included inside the arm 11 below a rotation range 24 of the rotor 12.
Abstract: The exponential growth in deep learning models is challenging existing computing hardware. Optical neural networks (ONNs) accelerate machine learning tasks with potentially ultrahigh bandwidth and nearly no loss in data movement. Scaling up ONNs involves improving scalability, energy efficiency, compute density, and inline nonlinearity. However, realizing all these criteria remains an unsolved challenge. Here, we demonstrate a three-dimensional spatial time-multiplexed ONN architecture based on dense arrays of microscale vertical cavity surface emitting lasers (VCSELs). The VCSELs, coherently injection-locked to a leader laser, operate at gigahertz data rates with a 7T-phase-shift voltage on the 10-millivolt level. Optical nonlinearity is incorporated into the ONN with no added energy cost using coherent detection of optical interference between VCSELs.
Type:
Application
Filed:
May 15, 2023
Publication date:
April 3, 2025
Applicants:
Massachusetts Institute of Technology, NTT Research, Incorporated
Inventors:
Zaijun Chen, Ryan HAMERLY, Dirk Robert ENGLUND
Abstract: An apparatus and a method for neural network computation are provided. The apparatus for neural network computation includes a first neuron circuit and a second neuron circuit. The first neuron circuit is configured to execute a neural network computation of at least one computing layer with a fixed feature pattern in a neural network algorithm. The second neuron circuit is configured to execute the neural network computation of at least one computing layer with an unfixed feature pattern in the neural network algorithm. The performance of the first neuron circuit is greater than that of the second neuron circuit.
Type:
Grant
Filed:
December 23, 2020
Date of Patent:
April 1, 2025
Assignee:
Industrial Technology Research Institute
Abstract: The present invention relates to an apparatus for predicting a region-specific cerebral cortical contraction rate on the basis of a CT image.
Type:
Grant
Filed:
September 2, 2020
Date of Patent:
April 1, 2025
Assignees:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
Inventors:
Jun Kyung Seong, Sang Won Seo, Jeong Hun Kim, Sihyeon Kim
Abstract: An aircraft with an aircraft fuselage, and a passenger cabin and a cockpit, where the aircraft includes a center-forward attendant space between the passenger cabin and the cockpit. A cabin crew member of the aircraft can stand in the center-forward attendant space for monitoring progress of an emergency evacuation of the aircraft. The aircraft has one or more emergency exits for providing egress of passengers from the aircraft fuselage during the emergency evacuation. The aircraft also has a situational awareness monitoring (SAM) system for use in evacuating the passengers from the aircraft during the emergency evacuation. The SAM system includes one or more imaging devices and one or more display modules, each of which displays within the passenger cabin images captured by a corresponding one of the one or more imaging devices.
Type:
Grant
Filed:
December 21, 2022
Date of Patent:
April 1, 2025
Assignees:
Airbus Americas, Inc., Airbus Operations GmbH, National Research Council of Canada
Inventors:
Joyce S. T. Tan, Tina Kay Griffin, Patrick Alexander Rollfink, Christophe J. P. J. Legare, Natalia Cooper, John Russell Thomas, Shelley M. Roberts, Caidence S. Paleske
Abstract: A microsensor module includes: one or more microsensors; a power supply; communication circuit; and processing circuitry. The processing circuitry may be configured to: receive data measured by the one or more microsensors; process the measured data to determine a plurality of different performance parameters related to technique of an athlete when performing a sport; and output, using the communication circuit, real-time information about the correctness of technique and performance level of the athlete performing the sport, wherein the microsensor module is encapsulated in a water-proof package that is attachable or adjoinable to the athlete's body.
Type:
Grant
Filed:
November 17, 2021
Date of Patent:
April 1, 2025
Assignee:
Corporation for National Research Initiatives
Abstract: Disclosed are a method and an apparatus of digital feedback based adaptive delay time control for a high efficiency active rectifier. According to the present invention, provided is an apparatus for digital feedback based adaptive delay time control, which adaptively compensates a driving delay of a switch by controlling a time of a delay circuit through a digital feedback-based compensation technique, and operate the switch at an appropriate timing in spite of changes in operation environments such as an input voltage and a load to increase the efficiency of an AC-DC rectifier.
Type:
Grant
Filed:
March 27, 2023
Date of Patent:
April 1, 2025
Assignee:
Korea University Research and Business Foundation
Abstract: A system for automatically closing a trunk lid of a vehicle. The system comprises a trunk sensor system configured for detecting items in a luggage trunk, a trunk lid actuator for automatic closing of the trunk lid, and a control unit connected to the trunk sensor system and to the trunk lid actuator.
Type:
Grant
Filed:
July 22, 2022
Date of Patent:
April 1, 2025
Assignees:
Ningbo Geely Automobile Research & Dev. Co., Ltd., ZHEJIANG GEELY HOLDING GROUP CO., LTD.
Inventors:
Jonathan Johansson, Erik Lindberg Nilsson
Abstract: A rotary engine that generates electricity using differences in relative humidity. A water-responsive material expands and contracts as water evaporates which drives the rotation of two wheels. The rotary motion drives an electrical generator which produces electricity. In another embodiment, the water-responsive material is used to actuate an artificial muscle of a robotic device.
Type:
Grant
Filed:
March 26, 2021
Date of Patent:
April 1, 2025
Assignee:
Research Foundation of the City University of New York
Inventors:
Xi Chen, Rein V. Ulijn, Zhi-Lun Liu, Yi-Ren Wang, Daniela Kroiss, Haozhen Wang