Abstract: A system and method for creating multi-phase kidney computed tomography (CT) images of a patient are provided. The method includes acquiring or accessing CT data that includes a first dataset acquired from the patient during a first phase when a dose of a contrast agent is being excreted from a kidney of the patient and does not include a second dataset acquired from the patient during a second phase after the dose of the contrast agent is delivered but before the dose of a contrast agent is being excreted from a kidney.
Abstract: An apparatus for image segmentation according to an embodiment includes an acquirer configured to acquire one or more images in which an object is photographed and a segmentation performer configured to perform segmentation on the one or more images using a segmentation model which is deep learned through a plurality of images, in which the segmentation model is a U-Net-based model including a first type module based on depth-wise separable convolution (DSC) and a second type module based on global context network (GCNet).
Type:
Grant
Filed:
April 19, 2022
Date of Patent:
April 8, 2025
Assignee:
RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY
Abstract: The present invention relates to peptides, in particular cell-penetrating peptides, and to conjugates of such cell-penetrating peptides with a therapeutic molecule. The present invention further relates to use of such peptides or conjugates in methods of treatment or as a medicament, especially in the treatment of genetic disorders and in particular muscular dystrophies such as Duchenne muscular dystrophy.
Type:
Grant
Filed:
August 9, 2019
Date of Patent:
April 8, 2025
Assignees:
Oxford University Innovation Limited, United Kingdom Research and Innovation
Inventors:
Matthew Wood, Raquel Manzano, Caroline Godfrey, Graham McClorey, Richard Raz, Michael Gait, Andrey Arzumanov, Liz O'Donovan, Gareth Hazell, Ashling Holland, Miguel Varela
Abstract: The inorganic particle according to the present invention is composed of aggregation of crystalline and amorphous small particles and has a spherical and smooth surface. The spherical appearance, low crystallinity and narrow particle size distribution of inorganic particle are more advantageous in reducing scratch defects in the CMP process. In addition, since the small particles on the surface of the inorganic particle provide more active sites, the inorganic particle has an excellent removal rate, so it is advantageous as a next-generation CMP abrasive.
Type:
Grant
Filed:
February 26, 2021
Date of Patent:
April 8, 2025
Assignees:
BEAD ORIGIN INC., Research & Business Foundation SUNGKYUNKWAN UNIVERSITY
Inventors:
Jae-Do Nam, Na-Yeon Kim, In-Kyung Park, Uiseouk Hwang, Donghak Kim
Abstract: A suture-carrying apparatus includes a suture engaging ridge for placement and retention of surgical sutures, and a base for conveniently mounting the apparatus to a predetermined location, such as a body structure, which is reachable by robotic arms during a robot-assisted surgical operation. The base may be configured to allow stability of the apparatus for one-handed placement and retrieval of sutures from the ridges.
Type:
Grant
Filed:
April 14, 2020
Date of Patent:
April 8, 2025
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: The present disclosure discloses a sensing function control node for an Internet of Things (IoT), and relates to technical field of electrical communication. The node includes an accessing module for sensors and actuators, a data format analyzing and integrating module and a transmission accessing and connecting module. Software-defined optical access technologies are utilized to control original sensing data in the IoT to access the accessing module for the sensors and the actuators. Status information of modules in the node is sensed in real time through a software-defined unified control plane, to adjust upload rates of modules and control the connections between sensing function control node and EAN. The original sensing data in IoT are transmitted to the transmission accessing and connecting module after being pre-processed. The pre-processed data are transmitted to EAN through upload channels between the sensing function control node and EAN established.
Type:
Grant
Filed:
August 18, 2022
Date of Patent:
April 8, 2025
Assignee:
NANJING XIGUANG RESEARCH INSTITUTE FOR INFORMATION TECHNOLOGY CO., LTD
Inventors:
Xiaohan Sun, Xiaokai Ye, Kun Huang, Tao Lyu, Jun Zhao, Qiugun Miao, Jinhui Li, Xuekang Shan
Abstract: A transparent gel electrolyte comprising a polymeric gelling agent, a lithium or ammonium salt ionic conductor, molecular iodine and a solvent selected from water, water and DMSO or water and alcohol. This electrolyte can be used in electrochromic devices.
Type:
Grant
Filed:
February 15, 2021
Date of Patent:
April 8, 2025
Assignee:
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860)
Abstract: Described herein are diagnostic and control fusion protein reagents and methods for use thereof in simple rapid and inexpensive hemagglutinin assays for the detection of subject antibodies directed to the SARS-CoV-2 virus.
Abstract: Provided are methods, devices, and systems for identifying the concentration of delta-9-tetrahydrocannabinol (?-9 THC) in a given sample. The system allows for in situ formation of a chromophore eliminating the use of chloroform, wherein said chromophore absorbance spectra is measured using a spectroscopy method within a light wavelength range. The system allows for calculating the concentration of ?-9 THC using the linear relationship between the ?-9 THC level and the intensity of the color change in the present tester. Said linear relationship is obtained because the tester of the present disclosure allows the chromophore formation reaction go to completion.
Abstract: The present disclosure provides compositions, methods, kits, and platforms for selectively activating and deactivating chimeric receptor effector cells using humanized chimeric receptor effector cell switches that comprise a humanized targeting moiety that binds CD19 on a target cell and a chimeric receptor interacting domain that binds to a chimeric receptor effector cell and/or chimeric receptor effector cell switches comprising optimized chimeric receptor interacting domains. Also disclosed are methods of treating disease and conditions with such chimeric receptor effector cells and chimeric receptor effector cell switches.
Type:
Grant
Filed:
August 30, 2021
Date of Patent:
April 8, 2025
Assignee:
The Scripps Research Institute
Inventors:
Travis S. Young, Leonard Presta, David Rodgers, Eric Hampton, Timothy Wright, Peter G. Schultz, Eduardo Laborda, Elvira Khialeeva, Sophie Viaud
Abstract: The technology subject of the present application concerns a novel class of fused nanocrystal molecules having unique electronic properties. The application further contemplates methods for their preparation and methods of their use.
Type:
Grant
Filed:
January 14, 2020
Date of Patent:
April 8, 2025
Assignee:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: An apparatus for measuring contamination on a critical surface of a part is provided. A vessel for mounting the part is provided. An inert gas source is in fluid connection with the vessel and adapted to provide an inert gas to the vessel. At least one diffuser receives the inert gas from the vessel, wherein the critical surface of the part is exposed to the inert gas when the part is mounted in the vessel. At least one analyzer is adapted to receive inert gas from the at least one diffuser and measures contaminants in the inert gas.
Type:
Grant
Filed:
September 5, 2019
Date of Patent:
April 8, 2025
Assignee:
Lam Research Corporation
Inventors:
Amir A. Yasseri, Girish M. Hundi, John Michael Kerns, Duane Outka, John Daugherty, Cliff La Croix
Abstract: A method for preparing an aramid nanofiber dispersion includes dissolving an aromatic polyamide-based polymer in a solution including a basic material and an aprotic polar solvent, while performing stirring so that a nanofiber is produced, wherein the aromatic polyamide-based polymer is a polymer in a form of a solid which is not spun into a fiber form, the stirring is performed at a temperature of 50° C. or lower and at a speed of 10-1000 rpm so that a time taken for the aromatic polyamide-based polymer to be dissolved and formed into an aramid nano-fiber dispersion is 80 hours or less, an aramid nanofiber in the aramid nanofiber dispersion has an average diameter of 1 to 100 nm and an average length of 0.1 to 100 ?m, and the basic material includes potassium hydroxide or sodium hydroxide.
Type:
Grant
Filed:
March 19, 2019
Date of Patent:
April 8, 2025
Assignee:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Jeyoung Park, Dong Yeop Oh, Sung Yeon Hwang, Hyun Gil Cha, Jong Geon Jegal, Ho Jun Kim, Seul A Park
Abstract: A polymer-based sensor for detecting agricultural analytes is disclosed, including stable polymer-based sensing films such as molecular imprinted polymers (MIPs) that can be incorporated in sensors for detecting herbicides and pesticides, as well as methods of making the sensing films.
Abstract: There is provided a method of determining an order of encrypted inputs, including a first encrypted input and a second encrypted input, using at least one processor, the first encrypted input including a first encrypted data and the second encrypted input including a second encrypted data, each of the first and second encrypted data being encrypted based on a homomorphic encryption scheme, the method including: generating a first series of encrypted blocks from the first encrypted data and a second series of encrypted blocks from the second encrypted data; performing a first block-wise operation between the first series of encrypted blocks and the second series of encrypted blocks to obtain a first series of block-wise outputs; performing a second block-wise operation between the first series of encrypted blocks and the second series of encrypted blocks to obtain a second series of block-wise outputs; and determining an order of the first and second encrypted data based on the first series of block-wise outpu
Type:
Grant
Filed:
February 13, 2020
Date of Patent:
April 8, 2025
Assignee:
Agency for Science, Technology and Research
Inventors:
Hong Meng Benjamin Tan, Khin Mi Mi Aung
Abstract: Provided is a Pichia pastoris mutant strain for expressing an exogenous gene. Specifically, provided is a Pichia pastoris mutant strain comprising, with respect to Pichia pastoris mutant strain GS115 or CICC32806, one or more of the following six mutations: BQ9382_C1-2260, EKK deletions at positions 308-310, a hypothetical protein; BQ9382_C1-3800, E129K, 60S ribosomal subunit assembly/exported protein LOC1; BQ9382_C1-5700, 1312M, mitochondrial external NADH dehydrogenase, type II NAD(P)H: quinone oxidoreductase; BQ9382_C2-3950, Q145X, an essential protein having a binding partner Psr1p and used for completely activating a general stress response; BQ9382_C3-2220, E188K, a hypothetical protein; and BQ9382_C3-4370, W196X, orotidine 5\?-phosphate decarboxylase. The provided Pichia pastoris mutant strain is an effective commonly employed host for exogenous expression, and can efficiently express different proteins, especially phospholipase and lipase.
Type:
Grant
Filed:
December 27, 2019
Date of Patent:
April 8, 2025
Assignee:
WILMAR (SHANGHAI) BIOTECHNOLOGY RESEARCH & DEVELOPMENT CENTER CO., LTD.
Abstract: A new and distinct apple variety is described. The variety results from crossing the apple varieties ‘Cripps Pink’ (U.S. Plant Pat. No. 7,880) and ‘Scilate’ (U.S. Plant Pat. No. 20,477) in Havelock North, New Zealand. The fruit of the apple tree of this new variety have an attractive appearance characterized by its dark red color and it notable for its long storage life. This new variety has been named ‘HOT141A1’.
Type:
Grant
Filed:
May 1, 2024
Date of Patent:
April 8, 2025
Assignees:
The New Zealand Institute for Plant and Food Research Limited, Institut De Recerca I Tecnologia Agroalimentaries (IRTA), FruitFutur A.I.E.