Patents Assigned to Research
  • Patent number: 11926666
    Abstract: The present invention relates to a bispecific antibody construct comprising a first human binding domain which binds to human CDH3 on the surface of a target cell and a second binding domain which binds to human CDS on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: March 12, 2024
    Assignee: AMGEN RESEARCH (MUNICH) GMBH
    Inventors: Bertram Weiss, Anna-Lena Frisk, Ruprecht Zierz, Peter Kufer, Tobias Raum, Doris Rau, Jonas Anlahr, Ralf Lutterbüse, Lisa Nahrwold, Christoph Dahlhoff, Claudia Blümel, Patrick Hoffmann
  • Patent number: 11927974
    Abstract: The flow rate control device includes a main plate corresponding to an inner diameter and including a through hole which is formed at the center thereof and through which a fluid flows, a sub-plate corresponding to a size of the through hole, disposed in front of the main plate, and applied with a pressure of the flowing fluid, and an expansion and contraction flow path formed to connect the through hole and a circumference of the sub-plate to each other and expanded and contracted by the pressure applied to the sub-plate. The expansion and contraction flow path includes a plurality of holes which are formed in a side surface thereof and through which the flow flows, and has a cross-sectional area changed by the pressure to control a flow rate.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: March 12, 2024
    Assignee: Korea Aerospace Research Institute
    Inventors: Kwang Kun Park, Jun Seong Lee, Kee Joo Lee
  • Patent number: 11925897
    Abstract: Provided is a biomaterial removing device including an air injection part, a first processing part spaced apart from the air injection part, and a second processing part spaced apart from the air injection part with the first processing part therebetween, wherein the first processing part includes a first biomaterial removing part configured to remove biomaterials included in air collected from the air injection part and a first monitoring part, and the second processing part includes a second biomaterial removing part configured to remove the residual biomaterials and a second monitoring part, wherein the first biomaterial removing part includes a dry air purifier, the second biomaterial removing part includes a wet air purifier, and the first biomaterial removing part and the second biomaterial removing part each include an image sensor.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: March 12, 2024
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Jin Tae Kim
  • Patent number: 11927804
    Abstract: A wavelength division multiplexing device includes an alignment substrate configured to provide alignment between optical components of the device. The device includes a plurality of collimating lenses, and the alignment substrate includes a plurality of aligners. Each of the aligners is configured to place a respective one of collimating lenses in a predetermined position and a predetermined orientation with respect to the other collimating lenses. The alignment substrate thereby provides passive alignment of the collimating lenses with a designed optical path. The substrate may also include visual alignment markings that provide an indication of the placement of multi-layer thin film filters so that the filters define an actual optical path in alignment with the designed optical path, and integrated optical waveguides that provide an optical beam to each of the collimating lenses.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: March 12, 2024
    Assignee: CORNING RESEARCH & DEVELOPMENT CORPORATION
    Inventor: Eric Stephan ten Have
  • Patent number: 11927609
    Abstract: Disclosed are various embodiments for an anomaly detection system for detecting and identifying anomalies in electrical devices based on an energy profile associated with the electrical devices. Energy profile data associated with electrical devices or components in a power network can be obtained using an energy meter. The energy profile data can be analyzed to determine one or more conditions of the electrical devices. An anomaly of the electrical devices can be determined based on the energy profile data and conditions. Further, a root cause of the anomaly can be determined.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: March 12, 2024
    Assignee: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
    Inventors: WenZhan Song, Yang Shi, Fangyu Li, Jin Ye
  • Patent number: 11926356
    Abstract: A method and device of multi-train operation trend deduction. Temporary speed limit information, scheduling information, line information and train status information are obtained; the coupling relationship between the trains traction calculation and the area of space-time scope which is under temporary speed limit are analyzed, and the time saving driving strategy of the first train within the time domain is calculated; according to the running position and speed of the front train, a multi-train operation tracking model under different block systems is established; according to the temporary speed limit information, the driving strategy of following tracking train is deduced, and the operation of the multi-train is calculated; the operation trend of multi-train to the driving scheduling platform is sent.
    Type: Grant
    Filed: December 30, 2022
    Date of Patent: March 12, 2024
    Assignees: CHINA ACADEMY OF RAILWAY SCIENCES CORPORATION LIMITED SIGNAL & COMMUNICATION RESEARCH INSTITUTE, BEIJING HUATIE INFORMATION TECHNOLOGY Co., Ltd., CHINA ACADEMY OF RAILWAY SCIENCES CORPORATION LIMITED, BEIJING RUICHI NATIONAL RAILWAY INTELLIGENT TRANSPORT SYSTEM ENGINEERING TECHNOLOGY Co., Ltd.
    Inventors: Rongsheng Wang, Qi Zhang, Zhiming Yuan, Tao Zhang, Tao Wang, Shuxin Ding
  • Patent number: 11927432
    Abstract: A system for a molded power charge with secondary pellet at each end. The molded power charge includes a solid outer wall which extends for the length. The solid outer wall has a first end and a second end. The power charge further includes a secondary pellet at each end. The first end and the second end of the outer wall include a secondary pellet with an exposed face. This allows the power charge to be ignited from either end.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: March 12, 2024
    Assignee: PYROTECHNICS RESEARCH CENTER LLC
    Inventors: Ghassan Azar, Johnny Esquibel, Andy Pearce
  • Patent number: 11927151
    Abstract: An inlet duct for use with an engine is presented. The invention includes a duct structure, at least one spike disposed along an interior surface of the duct structure, and an inlet throat formed by one or more apexes disposed along an equal number of spikes. The inlet throat corresponds to the minimum cross-sectional area through which airflow passes as otherwise allowed by the maximal obstruction formed by the apex(es) within the duct structure. Each spike is bounded by a longitudinal ridge and a lateral ridge along an upper end and a base. The ridges intersect at the apex. A portion of each spike upstream of the inlet throat functions primarily as a supersonic diffuser and downstream as a subsonic diffuser. Airflow is isentropically compressed and then expanded within the inlet duct so that greater-than-subsonic flow at an input end is reduced to subsonic flow at an output end.
    Type: Grant
    Filed: July 10, 2023
    Date of Patent: March 12, 2024
    Assignee: Combustion Research and Flow Technology, Inc.
    Inventors: Neeraj Sinha, Stephen M. Barr, Michael R. O'Gara
  • Patent number: 11928815
    Abstract: The present disclosure provides a medical image analysis method and apparatus. The medical image analysis method according to an exemplary embodiment includes: receiving a frontal image of a spine; separating vertebral bodies from a vertebrae constituting the spine in the frontal image and extracting a contour of each of the vertebral bodies; deforming a 3D vertebral body model prepared in advance to match with the contour of each vertebral body; detecting an upper plane and a lower plane of each vertebral body in a matched 3D vertebral body model; determining an inclination of each vertebral body based on the upper plane and the lower plane of each vertebral body; and calculating a Cobb's angle based on the inclination of the vertebral body.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: March 12, 2024
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Hang Kee Kim
  • Patent number: 11925726
    Abstract: The present disclosure is related to a perfusable-type bio-dual proximal tubule cell construct and a producing method thereof capable of applying an in vitro artificial organ model configured to include a first bioink comprising a decellularized substance derived from a mammalian kidney tissue and human umbilical vascular endothelial cells (HUVECs) and a second bioink comprising the decellularized substance and renal proximal tubular epithelial cells (RPTECs), wherein the first bioink and the second bioink are coaxial and printed in tubular constructs having different inner diameters. According to the present disclosure, it is possible to use the renal proximal tubule-on-a-chip as a bioreactor capable of observing a biological drug reaction similar to a real drug by perfusing various drugs to the renal proximal tubule-on-a-chip.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: March 12, 2024
    Assignees: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION, THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY—ACADEMIC COOPERATION FOUNDATION
    Inventors: Dong-Woo Cho, Wonil Han, Narendra K. Singh, Yong Kyun Kim, Sun Ah Nam
  • Patent number: 11925643
    Abstract: Peptides, peptidomimetics and small molecules, collectively referred to as “decoy peptides”, are provided, which interfere with binding to a TIR domain of a toll-like receptor 4 (TLR4), and inhibit a TLR4-induced signaling pathway. These decoy peptides may be useful for treating diseases associated with induction of TLR4 signaling pathway such as a disease or disorder secondary to a cardiovascular disease, sepsis or an inflammatory disease.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: March 12, 2024
    Assignees: MOR RESEARCH APPLICATIONS LTD., BAR-ILAN UNIVERSITY
    Inventors: Edith Hochhauser, Arie-Lev Gruzman, Elena Trifonov
  • Patent number: 11926773
    Abstract: Provided herein are organic-inorganic hybrid-perovskites, including metal halide perovskites having a 1D crystal structure. The metal halide perovskites may be luminescent. The metal halide perovskites may include a dopant, including an emitter dopant. Methods of forming metal halide perovskites, and devices including the metal halide perovskites also are provided.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: March 12, 2024
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Biwu Ma, Zhao Yuan, Chenkun Zhou
  • Patent number: 11928331
    Abstract: A system, method and computer program product for managing the storing of data before usage of at least a first vehicle. The method includes receiving an indication of at least a first user library data file desired to be locally stored in at least a first vehicle memory for future use by a user, determining if the at least first user library data file matches at least a first vehicle library data file already stored in the at least first vehicle memory, and downloading, the at least first user library data file not already stored in the at least first vehicle memory of the at least first vehicle.
    Type: Grant
    Filed: November 20, 2021
    Date of Patent: March 12, 2024
    Assignee: NINGBO GEELY AUTOMOBILE RESEARCH & DEV. CO., LTD.
    Inventors: Magnus Nilsson, Erik Lindberg Nilsson
  • Patent number: 11927117
    Abstract: A method for converting heat to mechanical work including providing incoming heat transfer fluid (HTF) at a first temperature to a mixing chamber, providing incoming compressed gas at a second temperature to the mixing chamber, enabling the gas and the HTF to mix, producing a gas-and-HTF mix, enabling the HTF in the gas-and-HTF mix to heat the gas and isothermal expansion of the gas in the gas-and-HTF mix, limiting volume of the gas-and-HTF mix, thereby increasing pressure of the gas and causing acceleration of a flow of the gas-and-HTF mix, causing the gas-and-HTF mix to eject through a nozzle, thereby converting the heat of the HTF to kinetic energy, and using the kinetic energy to produce mechanical work. Related apparatus and methods are also described.
    Type: Grant
    Filed: August 30, 2021
    Date of Patent: March 12, 2024
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Carmel Rotschild, Joseph Cassell
  • Patent number: 11926687
    Abstract: A grafted polypropylene resin is prepared by a grafting reaction of a polar monomer capable of absorbing microwave so as to raise its temperature in a microwave field to more than 200° C. and a solid polypropylene resin using microwave irradiation without adding an initiator. The polar grafted polypropylene resin that does not contain initiator residues and does not have a significant reduction in molecular mass compared with a resin before grafting is obtained.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: March 12, 2024
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION
    Inventors: Jinliang Qiao, Songhe Wang, Xiaohong Zhang, Guicun Qi, Zhihai Song, Chuanlun Cai, Xiang Wang, Jinmei Lai, Binghai Li, Haibin Jiang, Yue Ru, Jiangru Zhang, Jianming Gao, Hongbin Zhang, Peng Han, Wenlu Liu
  • Patent number: 11927553
    Abstract: An apparatus for bulk ore sorting using gamma activation analysis is disclosed. The apparatus includes a conveyor system that includes one or more conveyor belts, surrounded by one or more radiation shields, to transport ore material along a transport path. A pulsed X-ray radiation source is configured to irradiate ore material at an irradiation region and one or more detectors are configured to detect a gamma radiation output from irradiated ore material at a detection region. The transport path has a bend, located between the irradiation region and the detection region, and about a vertical axis, of at least 45 degrees. The one or more detectors are configured to detect a radiation output from the irradiated ore material at times between X-ray pulses of the pulsed X-ray radiation source irradiating the ore material.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: March 12, 2024
    Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Peter Coghill, James Tickner, Chanel Tissot, Ian Carter, Nicholas Cutmore
  • Patent number: 11926647
    Abstract: The invention encompasses components from microbial cells which are useful for antibody production, including peptides, polypeptides comprising these peptides, polynucleotides which encode these peptides or polypeptides, and antibodies directed to these peptides, polypeptides, or polynucleotides. The invention also encompasses to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further encompasses methods and compositions, especially vaccine compositions, for detecting, targeting, and inhibiting microbial cells, especially methanogen cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: March 12, 2024
    Assignee: Pastoral Greenhouse Gas Research Limited
    Inventors: Eric Heinz Altermann, Graeme Trevor Attwood, Dong Li, William John Kelly, Zhanhao Kong, Sinead Christine Leahy
  • Patent number: 11926000
    Abstract: A refrigerator includes a vacuum adiabatic body including a conductive resistance sheet providing a vacuum space that has a temperature between a temperature of an internal space and a temperature of an external space and is in a vacuum state, the conductive resistance sheet capable of resisting heat conduction between a first plate and a second plate, wherein at least one of the conductive resistance sheet and each of the first and second plates are welded to each other to create a welding part, wherein a plurality of regular beads are provided to a surface of the welding part, and wherein the plurality of regular beads includes: a parabolic inflection region provided at a center portion; linear regions respectively provided at both outsides of the inflection region; and edge regions respectively provided at outsides of the linear regions.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: March 12, 2024
    Assignees: LG ELECTRONICS INC., UNIST ACADEMY-INDUSTRY RESEARCH CORPORATION
    Inventors: Wonyeong Jung, Deokhyun Youn, Jangseok Lee, Hyungson Ki
  • Patent number: 11925730
    Abstract: The present invention discloses a method for preventing retraction of aqueous drops on a hydrophobic surface. The present invention also discloses a medical device coated with a hydrophilic coating comprising a substrate and a coating composition.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: March 12, 2024
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Guruswamy Kumaraswamy, Manoj Kumar, Mayuresh Arvind Kulkarni
  • Patent number: 11929235
    Abstract: Systems and methods for tuning a megahertz radio frequency (RF) generator within a cycle of operation of a kilohertz (kHz) RF generator are described. In one of the methods, a predetermined periodic waveform is provided to a processor. The processor uses a computer-based model to determine plurality of frequency parameters for the predetermined periodic waveform. The frequency parameters are applied to the megahertz RF generator to generate an RF signal having the frequency parameters during one or more cycles of operation of the kilohertz RF generator.
    Type: Grant
    Filed: May 6, 2020
    Date of Patent: March 12, 2024
    Assignee: Lam Research Corporation
    Inventors: Arthur M. Howald, John C. Valcore, Jr.