Abstract: AXL-specific antibodies and uses therefor are described, including monoclonal and single domain antibodies. Such antibodies bind to cell surface expressed human AXL at an epitope in an immunoglobulin-like (IgL) domain of the AXL ectodomain. The antibody may be used in an antibody-drug conjugate (ADC), for example in the treatment, detection or staging of cancer. The antibody may be biparatopic.

Abstract: An optical radar includes an optical-signal receiving unit and an optical-signal pickup unit. The optical-signal receiving unit is configured to receive a reflected light. The optical-signal pickup unit is coupled to the optical-signal receiving unit and includes a first optical-signal filtering circuit and a second optical-signal filtering unit. The first optical-signal filtering circuit is configured to filter out a first interference pulse of the reflected light, wherein the first interference pulse has a first interference voltage value higher than a reference voltage. The second optical-signal filtering circuit is coupled to the first optical-signal filtering circuit and configured to generate a clock signal comprising a clock pulse; and filter out a second interference pulse that does not match the clock pulse in time point from the reflected light.

Abstract: A method may comprise: generating first and second FA sequences corresponding to first and second FAs, respectively, based on a first sequence; mapping elements of first and second FA signals, which are respectively generated by modulating the first and second FA sequences, to first and second subcarrier groups corresponding to the first and second FAs, first base station, and first symbol; generating third and fourth FA sequences corresponding to the first and second FAs, respectively, based on a second sequence; mapping elements of third and fourth FA signals, which are respectively generated by modulating the first and second FA sequences, to third and fourth subcarrier groups corresponding to the first and second FAs, second base station, and second symbol; and transmitting a first transmission signal including the first and second FA signals, and a second transmission signal including the third and fourth FA signals.

Abstract: A tent with a charging device and wiring thereof includes a main body that includes a frame and a wall, the frame being connected to the wall. The tent also includes an electrical component, which includes an electrical appliance, a power supply and an electric wire. The electrical appliance and the power supply are electrically connected through the electric wire, and the electrical appliance and the electric wire are detachably or fixedly arranged on the frame and/or the wall. For the tent with a charging device and wiring thereof, electrical appliances and electric wires are reasonably arranged on the frame or the wall of the tent in a fixed or manner, by which layout of electrical appliances and electric wires is more reasonable and regular, and the electrical appliances and electric wires will not occupy activity space in the tent, effectively improving users' experience on tents.

Abstract: Disclosed are a device and method for detecting distance reduction attack in an ultra-wide band (UWB) high rate pulse (HRP) mode. The method for detecting distance reduction attack is a method performed by a receiver or transmitter operating in the UWB HRP mode, the method comprising receiving a message frame targeted for distance reduction attack; splitting a scrambled timestamp sequence (STS) field included in the message frame into a plurality of sub-fields; computing a correlation between each of the sub-fields and a corresponding sub-template among a plurality of sub-templates split from a local template; extracting a plurality of maximum peaks, each corresponding to each of the correlations; and detecting the distance reduction attack based on extracted maximum peaks.

Abstract: Polymeric ion conductors composed of a polymeric or co-polymeric backbone which comprises a plurality of backbone units, a metal ligand attached to at least a portion of the backbone units, and a metal ion attached to the metal ligand are provided. The metal ligand can be an N-heterocyclic carbene ligand and the metal can feature low oxophilicity. lonomeric materials, including, for example, ion exchange membranes such as anion exchange membranes, made of the polymeric ion conductor, and electrochemical systems and articles-of-manufacturing containing the polymeric ion conductor or the ion exchange membrane are also provided.

Abstract: A drone swarm control method is provided. The drone swarm control method includes displaying a drone swarm and a three-dimensional (3D) terrain projected onto a virtual reality (VR) space by using a VR headset, based on user manipulation, selecting a small-scale drone swarm, provided in a region of interest (ROI) set in the 3D terrain, from the drone swarm by using a VR controller, based on the user manipulation, and dividing, by using a server, the ROI into a plurality of cells, respectively allocating the divided plurality of cells to drones included in the small-scale drone swarm, and automatically generating a 3D flight path of a drone allocated to each of the divided plurality of cells, based on user input information representing the small-scale drone swarm and the ROI.

Abstract: Disclosed are a brain image-based quantitative brain disease prediction method and apparatus. According to the present invention, there is provided a brain image-based quantitative brain disease prediction apparatus including a processor, and a memory connected to the processor, in which the memory stores program instructions executed by the processor to convert original images of multiple brain images into original radiomic, convert a synthetic image synthesized through counterfactual reasoning of the original image into a synthetic radiomic, estimate a difference between the original radiomic and the synthetic radiomic to extract a representative region of interest for brain disease prediction, and input the representative region of interest and brain images for each patient to a linear classifier including a counterfactual-guided attentive feature representation module to predict a disease state.

Abstract: Disclosed is a memory cell including a first transistor having a first terminal coupled to a bit line; a second transistor having a first terminal coupled to a bit line bar; a weight storage circuit coupled between a gate terminal of the first transistor and a gate terminal of the second transistor, storing a weight value, and determining to turn on the first transistor or the second transistor according to the weight value; and a driving circuit coupled to a second terminal of the first transistor, a second terminal of the second transistor, and at least one word line, receiving at least one threshold voltage and at least one input data from the word line, and determining whether to generate an operation current on a path of the turned-on first transistor or the turned-on second transistor according to the threshold voltage and the input data.

Abstract: In Hybrid and truncated immune cell proteins are described. Hybrid proteins are stimulatory and include an extracellular domain of one stimulatory immune cell protein, an intracellular domain of a different stimulatory immune cell protein, and a transmembrane domain linking the extracellular domain to the intracellular domain. Truncated proteins include an immune cell receptor ligand and a transmembrane domain but lack a functional intracellular domain. The hybrid and truncated proteins can be used to modulate and/or diversify immune cell activation in the fight against cancers and infectious diseases, among other uses.

Abstract: Embodiments described herein provide a design architecture for co-designing a controller and a watermarking signal for a cyber-physical system. During operation, the architecture can determine, in conjunction with each other, respective values of a first set of parameters indicating operations of the controller and a second set of parameters representing the watermarking signal. Here, the watermarking signal is combinable with a control signal from the controller for monitoring an output signal of the cyber-physical system for detecting malicious data at different time instances. Subsequently, the architecture can determine a state manager for determining the states of the cyber-physical system from the monitored output signal based on the first and second sets of parameters. The architecture can also determine a detector capable of identifying presence of an attack from the states of the cyber-physical system at a plurality of time instances using the watermarking signal.

Abstract: This document provides materials and methods for treating a damaged optic nerve in a mammal to restore visual function comprising administering a population of induced pluripotent stem cell-derived oligodendrocyte precursor cells. This document also provides materials and methods for determining a remyelination potential quotient of a population of induced pluripotent stem cell-derived oligodendrocyte precursor cells. This document also provides materials and methods for screening factors that enhance maturation or myelination efficiency of an induced pluripotent stem cell-derived oligodendrocyte precursor cell or cells.

Abstract: A system for providing discharge monitoring of a firearm includes a first sensor, a trigger pull sensor assembly, an event detection module and a display. The first sensor senses a first acceleration along a first axis and sends a first input signal. The trigger pull sensor assembly senses mechanical movement of a trigger of the firearm, and communicates a second input signal corresponding to a position of the trigger. The event detection module receives the first input signal and compares the first acceleration to an acceleration threshold indicative of a shot; receives the second input signal and determines whether the second input signal is satisfies a second threshold indicative of a shot; determines whether a discharge has occurred based on both the first signal satisfying the acceleration threshold and the second input signal satisfying the second threshold; and generates an event detection signal based on the determination.

Abstract: A system and method for determining a performance metric based on a discharge event of a firearm includes receiving, by a first event detection module associated with a first firearm of a first user, a plurality of first input signals over a sample window of time from a first inertial measurement unit (IMU) configured on the first firearm. an occurrence of a first shot discharge of the first firearm at a first time based on the plurality of first input signals is identified by the first event detection module. A performance metric is determined based on the identifying. The performance metric is communicated to the user of the firearm in real-time.

Abstract: An engineered targeting exosome comprising; a modified Lamp2b peptide, a targeting peptide or antibody; and a Fc portion of IgG2b. The targeting peptide or antibody detects a target protein within a cell and precisely delivers the exosome to cells expressing the target protein and the Fc portion of IgGb2 induces antibody-dependent cell-mediated cytotoxicity (ADCC) events in cells expressing the target protein. Also disclosed are methods of using the engineered targeting exosome to detect and/or deplete cells expressing the target protein.

Abstract: A negative differential resistance device includes a dielectric layer having a first surface and a second surface opposing the first surface, a first semiconductor layer that includes a first degenerated layer that is on the first surface of the dielectric layer and has a first polarity, a second semiconductor layer that includes a second degenerated layer that has a region that overlaps the first semiconductor layer and has a second polarity, a first electrode electrically connected to the first semiconductor layer, a second electrode electrically connected to the second semiconductor layer, and a third electrode on the second surface of the dielectric layer and which has a region overlapping at least one of the first semiconductor layer or the second semiconductor layer.

Abstract: A package structure, including a circuit board, multiple circuit structure layers, at least one bridge structure, and at least one supporting structure, is provided. The circuit structure layer is disposed on the circuit board. The bridge structure is connected between the two adjacent circuit structure layers. The supporting structure is located between the two adjacent circuit structure layers, and the supporting structure has a first end and a second end opposite to each other and respectively connecting the bridge structure and the circuit board.

Abstract: A method of inducing multinucleated myotube formation is provided. The method comprising contacting myogenic precursor cells from a farmed animal with an Extracellular Regulated Signaling Kinase (ERK1/2) inhibitor and/or an upregulator of intracellular Ca 2+ and/or RXR/RAR agonists, enhancing fusion and myogenic maturation.

Abstract: A close-loop deep brain stimulation algorithm system for Parkinson's disease includes a memory and a processor. The processor includes a deep brain stimulation (DBS) simulation module, a virtual brain network module, a feature extraction module, and a reinforcement learning module. The deep brain stimulation simulation module is adapted to combine a deep brain stimulation waveform according to the stimulation frequency and the stimulation amplitude and output the deep brain stimulation waveform. The virtual brain network module is adapted to receive the deep brain stimulation waveform to output a synaptic signal and calculate a reward parameter. The feature extraction module is adapted to receive the synaptic signal and extract a plurality of feature values according to the synaptic signal.

Abstract: The present disclosure relates to a carbonic anhydrase complex and a method for preparing same, in which a conjugate of a carbonic anhydrase and a dockerin module is bound to a small cellulose binding protein including a cohesin module and a cellulose binding module (CBM) and method of manufacturing thereof. The complex, which includes a cellulose binding module, is immobilized on the surface of green algae, to increase access to a substrate and enzyme activity, thereby efficiently fixing carbon dioxide, and increasing the growth and lipid production of green algae without adding other carbon sources. The present disclosure is expected to be actively utilized in fields, such as biofuels, using carbon dioxide fixation.