Abstract: The present invention relates to inhibitors of insulin-regulated aminopeptidase (IRAP) and methods for inhibiting same, as well as compositions comprising said inhibitors. In particular, the inhibitors of the present invention may be useful in therapeutic applications including enhancing memory and learning functions.

Abstract: A photoluminescent nanofiber composite includes a nanofiber substrate, first luminescent particles, and second luminescent particles. The first luminescent particles are supported by the nanofibers and span at least a portion of a substrate surface, as a layer on the substrate surface, or with some particles located in a bulk of the substrate, or both. The second luminescent particles are disposed on the substrate. The second luminescent particles may be disposed directly on the substrate surface or on the first luminescent particles. The second luminescent particles may be deposited in a pattern of deposition units. The first and second luminescent particles are configured for emitting light of different respective wavelengths in response to excitation by a light beam. One or more surface treatment coatings may be provided at different locations.

Abstract: A lighting device may include a housing interior, a light exit, a light source, and a light converter. Output light is outputted from the light exit by emitting primary light from the light source. In response, the light converter emits secondary light of one or more wavelengths different than the primary wavelength, and the output light includes a combination of the primary light and the secondary light. The color of the output light may be tuned by adjusting a color parameter of the output light. The adjustment includes adding a color tuning material at a location in the housing interior where primary light is incident on the color tuning material. The color tuning material is configured for emitting auxiliary light in response to the incident primary light. Subsequently, the lighting device produces color-tuned output light that includes a combination of the primary light, the secondary light and the auxiliary light.

Abstract: A method and system are provided for computing a physiological presence of a user of a device. The method comprises obtaining a physiological measurement of the user of the device and computing a presence status based on physiological measurements.

Abstract: Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.

Abstract: Systems and methods for sharing previously-associated application data from a secure device can include a first device (e.g., a tablet computer) and a second device (e.g., a smartphone which can be a more secure device than the tablet computer) coupled to one another. The tablet computer can send a request to the smartphone for previously-associated input data associated with an application currently running on the tablet computer, an input field of the application, and an input entered in the input field of the application. The smartphone can transmit the previously-associated to the tablet computer. The previously-associated input data can include a browser history, frequently-visited websites, stored user credential data, auto-fill text data, or other previously-associated input data. As the previously-associated input data is stored on the smartphone (e.g., the more secure device), the likelihood of unauthorized access to the previously-associated input data can be reduced.

Abstract: Provided are a plastic microfluid control device having a multi-step microchannel and a method of manufacturing the same. The device includes a lower substrate, and a fluid channel substrate contacting the lower substrate and having a multi-step microchannel having at least two depths in a side coupling to the lower substrate. Thus, the device can precisely control the fluid flow by controlling capillary force in a depth direction of the channel by controlling the fluid using the multi-step microchannel having various channel depths. A multi-step micropattern is formed by repeating photolithography and transferred, thereby easily forming the multi-step microchannel having an even surface and a precisely controlled height.

Abstract: An electromagnetic bandgap structure comprising a progressive cascade of a plurality of patterns of cells. The cells of each pattern are dimensioned so that each pattern has a reflection phase response centered at a different, but closely-spaced, frequency compared with the reflection phase response of an adjacently positioned pattern, so that the combined reflection phase response of the plurality of patterns provides a continuous wideband operational range.

Abstract: In one embodiment, a scheme is provided for customization of a mobile communications device's data session retry mechanism in a wireless packet data service network. Upon detecting that a cause code has been returned by a node disposed in a wireless packet data service network, a structure is interrogated to determine if the cause code is mapped to a flag relating to the device's data session retry mechanism. Responsive to determining that the received cause code is mapped as a critical cause code, the data session retry mechanism of the mobile communications device is disabled so that further signaling messages towards the network are prevented.

Abstract: The invention provides a cell for preparing competent cells, wherein the cell is capable of spontaneously accumulating self-producing trehalose therein and the cell is used for the preparation of competent cells. The invention also provides a method for preparing competent cells, including: culturing the cell for preparing the competent cell mentioned previously to obtain a cell suspension; placing the cell suspension into an ice bath; centrifuging the cell suspension to obtain a cell precipitate; mixing a transform reagent with the cell precipitate; and obtaining competent cells suspension.

Abstract: The present invention relates generally to the field of synthetic crystal, and more particularly, this invention relates to doped low-temperature phase barium metaborate single crystal, growth method and frequency-converter. Molten salt method was adopted. The single crystal completely overcome the shortcomings of BBO with strong deliquescence, almost no deliquescence; its frequency doubling effect and optical damage threshold has improved greatly compared with the BBO; its hardness increased significantly, the single crystal with Shore hardness of 101.3 and Mohs hardness of 6, however, BBO with Shore hardness of 71.2 and Mohs hardness of 4. From the UV-Vis region transmittance curves tests, the cut-off wavelength of the single crystal is 190 nm, wavelength of absorption onset is 205 nm. BBSAG is widely applied in the fields of laser and nonlinear optics, and in terms of frequency-converter of ultraviolet and deep-ultraviolet due to its excellent properties better than BBO.

Abstract: A process for the efficient capture of CO2 and sulfur from combustion flue gas streams and gasification based fuel gas mixtures using regenerable and recyclable calcium based sorbents. The regeneration of the calcium sorbent is accomplished by hydrating the sorbent at high temperatures of about 600° C. and a pressure higher than 6 bars to lower the parasitic energy consumption.

Abstract: The present invention relates to a process for the polymerization of an olefin monomer. In particular, the present invention relates to a process for the polymerization of an olefin monomer and one or more optional comonomers in presence of a polymerization catalyst and hydrogen, said process being characterized by an improved control of the hydrogen concentration in the polymerization reactor. In addition, the present invention provides for an improved hydrogen feeding system to a polymerization reactor. Furthermore, the present invention provides for a polymerization reactor comprising such an improved hydrogen feeding system.

Abstract: The invention provides pyrrolidino-substituted 1,4-naphthoquinone derivatives that modulate the activity of protein kinases, and it relates to the use of the derivatives in pharmaceutical compositions for treating cardiovascular disorders and malignancies. The invention particularly provides medicaments for treating disorders associated with MAPKs signaling, ERKs signaling, p38 signaling, and JNKs signaling.

Abstract: A promoted activated carbon sorbent is described that is highly effective for the removal of mercury from flue gas streams. The sorbent comprises a new modified carbon form containing reactive forms of halogen and halides. Optional components may be added to increase reactivity and mercury capacity. These may be added directly with the sorbent, or to the flue gas to enhance sorbent performance and/or mercury capture. Mercury removal efficiencies obtained exceed conventional methods. The sorbent can be regenerated and reused. Sorbent treatment and preparation methods are also described. New methods for in-flight preparation, introduction, and control of the active sorbent into the mercury contaminated gas stream are described.

Abstract: It has been discovered that certain combinations of compounds are excellent penetration enhancers and, as such, can be incorporated in a topical formulation to facilitate administration of active agents. The increased penetration enhancement can also lead to a reduction in the total concentration of skin irritants in the formulation. There is described herein a topical formulation comprising (i) an active agent selected from at least one of lidocaine and tetracaine; (ii) a first compound, and (iii) a second compound, wherein the first compound and second compound are different, and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate and sodium lauryl sulfoacetate.

Abstract: Dehydrin- and late embryogenic abundant (LEA) protein-encoding polynucleotides from coffee plants are disclosed. Also disclosed are a promoter sequence from a coffee dehydrin gene, and methods for using these polynucleotides and promoter sequences for gene regulation and manipulation of flavor, aroma, stress tolerance and other features of coffee beans.

Abstract: Disclosed is a system and method for encryption of a scalable video coding (SVC) bitstream, which is the next-generation coding technology. The encryption method encrypts Network Abstraction Layer (NAL) data identified according to multidimensional scalability for space, time, and quality with respect to a bitstream created after an SVC encoding, thereby providing a multidimensional scalability function for space, time, and quality even after the encryption, so that the scalability is also maintained even in a bitstream extraction process after the encryption. According to such a scalable encryption method, a specific portion of an encrypted bitstream is removed in a bitstream extraction process, and user access to the bitstream is limited based on a combination of keys for accessing a specific scalability. Therefore, it is possible to protect scalable video content and to access the video content based on scalabilities.