Patents Assigned to Research
  • Patent number: 8541008
    Abstract: A Candida albicans bloodstream infections cause significant morbidity and mortality in hospitalized patients. Filament formation and adherence to host cells are critical virulence factors of C. albicans. Multiple filamentation regulatory pathways have been discovered, however the downstream effectors of these regulatory pathways remain unknown. The cell surface proteins in the ALS group are downstream effectors of the filamentation regulatory pathway. Particularly, Als1p mediates adherence to endothelial cells in vitro and is required for virulence. The blocking of adherence by the organism is described resulting from the use of a composition and method disclosed herein. Specifically, a pharmaceutical composition comprised of a gene, gene product, or specific antibody to the ALS gene family is administered as a vaccine to generate an immune response capable of blocking adherence of the organism.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: September 24, 2013
    Assignee: Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center
    Inventors: John E. Edwards, Jr., Scott G. Filler, Donald C. Sheppard, Ashraf S. Ibrahim, Yue Fu, Bradley J. Spellberg
  • Patent number: 8541539
    Abstract: A method for preparing a water-soluble polyamide, includes copolymerizing reactive monomers including caprolactam; ethylene glycol bis(2-aminoethyl)ether or ethylene glycol bis(3-aminopropyl)ether; and 5-sulfoisophthalic acid monosodium salt, wherein a molar ratio of caprolactam:ethylene glycol bis(2-aminoethyl)ether or ethylene glycol bis(3 -aminopropyl)ether:5-sulfoisophthalic acid monosodium salt is about 0:1:1 to about 5:1:1, advantageously about 1.85:1:1. Copolymerizing takes place at a copolymerization temperature of about 222-250° C. and a copolymerization pressure of about 3 Bar. The method further includes maintaining a temperature of about 222-250° C. for about 2-3 hours under normal pressure after the copolymerization step. The water-soluble polyamide has a solubility in water of about 10-70%.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: September 24, 2013
    Assignee: Taiwan Textile Research Institute
    Inventors: Yu-Chi Tseng, Chin-Wen Chen, S-P Rwei
  • Patent number: 8542276
    Abstract: An object tracking method for a non-overlapping-sensor network works in a sensor network. The method may comprise a training phase and a detection phase. In the training phase, a plurality of sensor information measured by the sensors in the sensor network is used as training samples. At least an entrance/exit is marked out within the measurement range of each sensor. At least three characteristic functions including sensor spatial relation among the sensors in the sensor network, difference of movement time and similarity in appearance, are estimated by an automatically learning method. The at least three characteristic functions are used as the principles for object tracking and relationship linking in the detection phase.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: September 24, 2013
    Assignee: Industrial Technology Research Institute
    Inventors: Chung-Hsien Huang, Cheng-Chuan Chou, Ruei-Cheng Wu
  • Patent number: 8541605
    Abstract: The present disclosure provides processes for the preparation of lipid conjugated cyclic carbonate derivatives. More specifically, the present disclosure is based on the finding that reacting lipids, such as, ceramides, with N,N?-disuccinimidyl derivative, resulted in the formation of, isolatable, substituted cyclic [1,3]-dioxan-2-one and [1,3]-dioxan-2-thione compounds. These isolatable cyclic substituted compounds and derivatives thereof may be used for various applications, such as in vaccination.
    Type: Grant
    Filed: May 11, 2008
    Date of Patent: September 24, 2013
    Assignees: Siolab Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Aaron Garzon, Jean Hildesheim
  • Patent number: 8540910
    Abstract: Disclosed is a method for making a refractory material from aluminum residues of aluminum recycling. At first, the aluminum residues is mixed with adhesive solution so that the percentage by weight of the adhesive solution is 5 wt % to 10 wt %. The mixture is granulated into grains. The grains are filled in a mold, pressed and then removed from the mold so that the grains are turned into a green body. The green body is heated in a furnace at a range of temperature from 1100° C. to 1400° C. so that the grains are sintered and become a refractory material.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: September 24, 2013
    Assignee: Atomic Energy Council—Institute of Nuclear Energy Research
    Inventors: Sheng-Fu Yang, Chun-Yen Yeh, Yen-Hua Chang, To-Mei Wang, Wen-Cheng Lee, Kin-Seng Sun, Chin-Ching Tzeng
  • Patent number: 8543587
    Abstract: A composite context information management apparatus and a method of providing composite context information using the same. The composite context information management apparatus includes a function providing unit configured to provide a composite context information function corresponding to the operation information from an application control unit; a composite context information processing unit configured to identify pieces of unit contexts and an operation rule based on the composite context information function and the name of the composite context information; and a composite context information presence unit configured to store the pieces of unit contexts corresponding to the name of the composite context information and an instance value for identification of the application and, in response to the application being executed in the user terminal, use the pieces of unit contexts and the operation rule to the user terminal.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: September 24, 2013
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Eung-Ha Kim, Su-Kyung Kim
  • Patent number: 8541333
    Abstract: A catalyst component for olefin polymerization comprising an ?-cyanosuccinate compound as an internal electron donor, a catalyst comprising the catalyst component, and use of the catalyst in olefin polymerization. When used in propylene polymerization, the catalyst can exhibit good catalytic activity and good hydrogen response, and the resulting polymer can have a good isotacticity and a good molecular weight distribution.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: September 24, 2013
    Assignees: China Petroleum & Chemical Corporation, Beijing Research Institute of Chemical Industry, China Petroleum & Chemical Corporation
    Inventors: Lunjia Xie, Yongtai Ling, Yu Tian, Zaixing Feng, Siyuan Zhao, Qing Hu, Zhufang Sun, Yu Kang
  • Patent number: 8539837
    Abstract: An embodiment is a method and apparatus for coherent ultrasonic imaging. A receiver array has a plurality of receiver elements on a substrate to detect in-phase and quadrature components of a received signal corresponding to a transmit signal. Each of the receiver elements includes a receiver transducer and a thin-film transistor (TFT) receiver circuit. The TFT receiver circuit includes a quadrature detector having a mixer to mix a received signal with a reference signal in a composite bias signal that is distributed across the plurality of receiver elements. A transmitter is acoustically coupled to the plurality of receiver elements to generate the transmit signal through an imaging medium.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: September 24, 2013
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Serena Han Ying Wong, Jeng Ping Lu, Raj B. Apte
  • Patent number: 8543155
    Abstract: A first roadside equipment operates as a transmitting/receiving mode in a control channel interval of an Nth synchronization interval so as to support a handover. In this instance, a second roadside equipment neighboring to the first roadside equipment operates as a receiving mode in the control channel interval of the Nth synchronization interval. The first roadside equipment operates as the receiving mode in a control channel interval of an (N+1)th synchronization interval. In this instance, the second roadside equipment operates as the transmitting/receiving mode in the control channel interval of the (N+1)th synchronization interval.
    Type: Grant
    Filed: August 1, 2011
    Date of Patent: September 24, 2013
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Sangwoo Lee, Hyun Kyun Choi, Hyun Seo Oh
  • Patent number: 8542571
    Abstract: Provided are a cell search method, a forward link frame transmission method, an apparatus using the methods, and a forward link frame structure. The cell search apparatus includes a sync acquirer acquiring synchronization of sync channel symbols using a sync channel of a forward link, and a group detector detecting at least one hopping codeword element belonging to a hopping codeword of a target cell from a forward link signal containing sync channel symbols sequence-hopped using a hopping codeword corresponding to a code group to which a scrambling code of each cell belongs based on the acquired synchronization, and detecting a code group of the target cell based on the detected hopping codeword element, wherein the hopping codewords are orthogonal to a cyclic shift operation. Accordingly, a cell search time and the complexity of the cell search can be reduced.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: September 24, 2013
    Assignees: Electronics and Telecommunications Research Institute, KT Corporation, SK Telecom., Co., Ltd
    Inventors: Il-Gyu Kim, Hyeong-Geun Park, Nam-Il Kim, Kap-Seok Chang, Young-Hoon Kim, Seung-Chan Bang
  • Patent number: 8541185
    Abstract: A method of determining responsiveness to cancer treatment is disclosed. The method comprises analyzing a frequency of tumor infiltrating lymphocytes (TILs) having a CD8+CD28?CD152? signature in a sample of the subject, wherein a frequency of TILs having the CD8+CD28?CD152? signature above a predetermined level is indicative of a positive responsiveness to cancer treatment. Other signatures reflecting responsiveness to cancer treatment are also disclosed. In addition, methods of treating cancer based on these signatures are also disclosed.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: September 24, 2013
    Assignees: Technion Research & Development Foundation Limited, Tel HaShomer Medical Research Infrastructure and Services Ltd.
    Inventors: Kfir Oved, Eran Eden, Martin Akerman, Roy Noy, Michal Besser, Yoram Reiter
  • Patent number: 8542962
    Abstract: Embodiments of endo-illuminators and related methods are disclosed. One embodiment of an illuminator can comprise a cannula defining a passage, an optical element disposed at an end of the cannula, and an optical fiber running through the passage with the distal end of the optical fiber in contact with the optical element. The optical fiber includes at least a heat preconditioned distal portion that terminates in the distal end that is in contact with the optical element.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: September 24, 2013
    Assignee: Alcon Research, Ltd.
    Inventors: Ronald T. Smith, Dean Y. Lin, Jack R. Auld, Timothy C. Ryan
  • Patent number: 8543407
    Abstract: A speech processing system which exploits statistical modeling and formal logic to receive and process speech input, which may represent data to be received, such as dictation, or commands to be processed by an operating system, application or process. A command dictionary and dynamic grammars are used in processing speech input to identify, disambiguate and extract commands. The logical processing scheme ensures that putative commands are complete and unambiguous before processing. Context sensitivity may be employed to differentiate data and commands. A multi faceted graphic user interface may be provided for interaction with a user to speech enable interaction with applications and processes that do not necessarily have native support for speech input.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: September 24, 2013
    Assignee: Great Northern Research, LLC
    Inventors: Jean Gagnon, Philippe Roy, Paul J. Lagassey
  • Patent number: 8543864
    Abstract: The present invention relates to an apparatus and method of performing an error recovery process in an asymmetric clustering file system that has higher efficiency in data recovery when a data server in an asymmetric clustering file system fails than a method of processing the data recovery in the metadata server. The present invention includes receiving a chunk list requiring recovery by a data server included in the other data server groups than a data server group including a failed data server among a plurality of data server groups, requesting chunk data necessary for recovering an erroneous chunk from a data server in the other data server groups to the other data servers than the failed data server in the data server group, and recovering the erroneous chunk based on the chunk data by the data server in the other data server group.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: September 24, 2013
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Sang-Min Lee, Young-Kyun Kim, Han Namgoong
  • Patent number: 8541542
    Abstract: The present invention relates to a process for reducing residuals content in a vinyl aromatic polymer, said residuals comprising essentially unpolymerized vinyl aromatic monomer, wherein the vinyl aromatic polymer in the molten state is brought in contact with a solid in powder capable to catalyze the alkylation of said residual vinyl aromatic monomer on the vinyl aromatic polymer. Advantage of the present invention is a sharp reduction of the unpolymerized vinyl aromatic monomer in the vinyl aromatic polymer without generating a new residual and without inducing a colored vinyl aromatic polymer. The present invention also relates to said vinyl aromatic polymer having a low residuals content.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: September 24, 2013
    Assignee: Total Research & Technology Feluy
    Inventors: Thomas-Maurice Roussel, Bruno Vuillemin, Francois Fajula
  • Patent number: 8540020
    Abstract: One or more methods, systems and computer readable mediums are utilized to provide treatment of a subterranean formation that contains solid organic matter, such as oil shale, tar sands, and/or coal formation. The treatment of the formation includes heating a treatment interval within the subterranean formation with one or more electrical in situ heaters. Available power, or other production resources, for the electrical heaters are determined at regular, predetermined intervals. Heating rates of the one or more electrical heaters are selectively controlled based on the determined available power at each regular, predetermined interval and based on an optimization model that outputs optimal heating rates for each of the electrical heaters at the determined available power.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: September 24, 2013
    Assignee: ExxonMobil Upstream Research Company
    Inventors: Matthew T. Stone, Ganesh Ghurye, Matthew T Shanley, Peter Rasmussen, Xianghui Huang, Robert D. Kaminsky
  • Patent number: 8542450
    Abstract: A two-axis, optical mount provides two sets of flexural elements monolithically and homogeneously formed of a single material with, and interconnecting, three rigid segments. Between each pair of rigid segments, beginning with the first and second, a set of extensions is formed to have a cross section that permits simple, easy, independent adjustment therebetween. Likewise, a flexural set exists between the second and third rigid elements. Meanwhile, the rigid elements have section moduli sufficiently great as to be orders of magnitude larger than the flexural stiffness or section modulus of the flexures, thus providing flexures that operate in the elastic mode and introduce no joint type accuracy errors in adjustment.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: September 24, 2013
    Assignee: Utah State University Research Foundation
    Inventors: Gregory Hopkins, Blake Crowther, Kendall Johnson, Vaughn A. Griffiths
  • Patent number: 8539746
    Abstract: A rope (3) is described for a tropospheric aeolian generator (1) composed, in length, of at least one first sector (4) adapted to resist to repeated flexure cycles, having a safety coefficient (S1), a diameter D(b1) and an aerodynamic resistance coefficient (CD1); at least one second sector (5) adapted to resist to repeated traction cycles with great load, having a safety coefficient S2<S1 and a diameter D(b2)<D(b1).
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: September 24, 2013
    Assignee: Kite Gen Research S.R.L.
    Inventor: Massimo Ippolito
  • Patent number: 8540843
    Abstract: A plasma processing system for processing a substrate is described. The plasma processing system includes a bottom piece including a chuck configured for holding the substrate. The plasma processing system also includes an induction coil configured to generate an electromagnetic field in order to create a plasma for processing the substrate. The plasma processing system also includes a cover covering at least the induction coil and a heating and cooling system.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: September 24, 2013
    Assignee: Lam Research Corporation
    Inventors: Leonard J. Sharpless, Keith Comendant
  • Patent number: 8541202
    Abstract: The invention relates to peptides which bind to MHC Class I and to MHC Class II molecules. These peptides are useful in different therapeutic and diagnostic contexts.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: September 24, 2013
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Alexander Knuth, Elke Jäger, Yao-tseng Chen, Matthew Scanlan, Ali Gure, Gerd Ritter, Lloyd J. Old, Jan W. Drijfhout