Abstract: The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.
Type:
Grant
Filed:
December 22, 2021
Date of Patent:
November 21, 2023
Assignees:
SINGAPORE HEALTH SERVICES PTE LTD, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventors:
Hau Wan Leung, Andre Boon Hwa Choo, Mei Yee Vanessa Ding, Shao Weng Daniel Tan, Narayanan Gopalakrishna Iyer
Abstract: Provided is an integrated DC/DC and AC/DC converter system including a main relay selectively connected to any one of an AC power supply unit and a DC power supply unit and a controller connecting the main relay to the AC power supply unit or the DC power supply unit. Electrical energy based on the AC power output from the AC power supply and electrical energy based on DC power output from the DC power supply unit may be selectively provided to a load.
Type:
Grant
Filed:
June 25, 2021
Date of Patent:
November 21, 2023
Assignee:
Korea Aerospace Research Institute
Inventors:
Jeong Eon Park, Gun Woo Moon, Ju Hyun Bae, Tae Woo Kim
Abstract: A gas mixture for treating a substrate in a substrate processing system includes hydrogen fluoride gas, a vapor of an alcohol, an additive consisting of a base, and a carrier gas. The gas mixture can be used to treat high aspect ratio (HAR) structures arranged on a surface of a substrate. A surface of the substrate may be spin rinsed using a first rinsing liquid. The first rinsing liquid is spun off from the surface of the substrate. The gas mixture is directed onto the surface of the substrate after the first rinsing liquid is dispensed.
Type:
Grant
Filed:
September 26, 2019
Date of Patent:
November 21, 2023
Assignee:
Lam Research AG
Inventors:
Ji Zhu, Gerome Michel Dominique Melaet, Nathan Lavdovsky, Rafal Dylewicz, David Mui
Abstract: The present disclosure relates to adhesive compositions made from the reaction product of plant protein and phenolics, and method of making and using the adhesive compositions. A maximum bonding strength of 7.8±1.5 MPa was obtained using only 1 weight % tannic acid in a zein matrix of pH=7 and cured at 120° C.
Abstract: Selective deposition of a sacrificial material on a semiconductor substrate, the substrate having a surface with a plurality of regions of substrate materials having different selectivities for the sacrificial material, may be conducted such that substantial deposition of the sacrificial material occurs on a first region of the substrate surface, and no substantial deposition occurs on a second region of the substrate surface. Deposition of a non-sacrificial material may then be conducted on the substrate, such that substantial deposition of the non-sacrificial material occurs on the second region and no substantial deposition of the non-sacrificial material occurs on the first region. The sacrificial material may then be removed such that net deposition of the non-sacrificial material occurs substantially only on the second region.
Type:
Grant
Filed:
January 15, 2019
Date of Patent:
November 21, 2023
Assignee:
Lam Research Corporation
Inventors:
Kashish Sharma, Taeseung Kim, Samantha Tan, Dennis M. Hausmann
Abstract: A Ni-based steam reforming catalyst having excellent carbon deposition resistance and sintering resistance is provided. The steam reforming catalyst is constituted by including nickel as a catalytically active metal, lanthanum as a first co-catalyst component, manganese as a second co-catalyst component, and a carrier containing ?-alumina as a main component.
Abstract: A vehicle seat arrangement includes a vehicle seat arranged to be adjusted between a forward facing setup and a rearward facing setup and a seat support structure. The vehicle seat has three seat parts, where a second seat part is pivotably connected to both a first seat part and a third seat part. The second seat part is pivotably connected to the seat support structure. In the forward facing setup, the first and second seat parts make up a seat back and the third seat part make up a seat cushion. In the rearward facing setup, the first seat part make up the seat cushion and the second and third seat parts make up the seat back of the vehicle seat.
Type:
Grant
Filed:
December 18, 2021
Date of Patent:
November 21, 2023
Assignee:
NINGBO GEELY AUTOMOBILE RESEARCH & DEVELOPMENT CO.
Inventors:
Oskar Ewehag, Johan Höcks, Christian Forsberg
Abstract: Hose has a body and a mouthpiece connected with the body. The mouthpiece is slidably placed against the body and is mounted at the end of the hose and includes a thickening. The ending has a circumferential stop placed in the axis of the mouthpiece. The stop has on its circumference a touch surface which is oriented inside, against the thickening on the mouthpiece. The mouthpiece is sealed by sealing ring against the body. The ring is placed in the sealing zone, or the mouthpiece is connected with the body by a flexible bellow. During the movement of the mouthpiece outside the touch surface and the outer surface of the hose in the zone with the thickening draw closer and the hose is held on the mouthpiece by the under pressure between the surface of the stop and the thickening.
Type:
Grant
Filed:
June 9, 2018
Date of Patent:
November 21, 2023
Assignee:
BJV RESEARCH, S.R.O.
Inventors:
Tibor Matyas, Branko Jass, Jan Tomas, Valer Kokos, Gabor Janos Bato
Abstract: A system and a method of black start for a combined operation of wind power, photovoltaic power, energy storage, and thermal power includes a renewable energy alternating current microgrid module, a power transmission and distribution module, and a thermal power generation module, the power transmission and distribution module is coupled to the renewable energy alternating current microgrid module and the thermal power generation module respectively. The renewable energy alternating current microgrid module includes a photovoltaic unit, a wind power unit, and an energy storage unit. The power transmission and distribution module is configured to transmit the electrical energy generated by the renewable energy alternating current microgrid module to the thermal power generation module. The thermal power generation module is configured to start an auxiliary equipment using the electrical energy transmitted by the power transmission and distribution module.
Type:
Grant
Filed:
June 21, 2023
Date of Patent:
November 21, 2023
Assignee:
Xi'an Thermal Power Research Institute Co., Ltd.
Abstract: Systems and methods for real-time control of temperature within a plasma chamber are described. One of the methods includes sensing a voltage in real time of a rail that is coupled to a voltage source. The voltage source supplies a voltage to multiple heater elements of the plasma chamber. The voltage that is sensed is used to adjust one or more duty cycles of corresponding one or more of the heater elements. The adjusted one or more duty cycles facilitate achieving and maintaining a temperature value within the plasma chamber over time.
Abstract: The present disclosure relates to an organic compound having the following structure, and an organic light emitting diode (OLED) and an organic light emitting device including the organic compound. The organic compound is a bipolar compound having a p-type moiety and an n-type moiety and has high energy level and proper energy bandgap for an emissive layer of the OLED. As the organic compound is applied into the emissive layer, the OLED can maximize its luminous properties as holes and electrons are recombined uniformly over the whole area in an emitting material layer (EML).
Type:
Grant
Filed:
July 16, 2020
Date of Patent:
November 21, 2023
Assignees:
LG DISPLAY CO., LTD., KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Abstract: Cannabinoid-loaded formulations are characterized by including 0.5 wt. % to 20 wt. % medium chain triglycerides, one or more hydrophilic surfactants, one or more co-surfactants and 0.1 wt. % or more of at least one cannabinoid. The formulations are in microemulsion form, and are fully dilutable by an aqueous diluent.
Type:
Grant
Filed:
September 28, 2017
Date of Patent:
November 21, 2023
Assignee:
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
Abstract: An embodiment of the disclosure provides a heater package including a substrate, a first barrier layer, at least one heater, and a second barrier layer. The first barrier layer is disposed on a surface of the substrate and has a first treatment layer on a side away from the substrate. The heater is disposed on the substrate and includes a heating layer and at least one electrode. The at least one electrode and the heating layer contact with each other. The second barrier layer covers an upper surface and a sidewall of the heater and has a second treatment layer on an opposite side or the side away from the substrate. A ratio of a thickness of the first treatment layer to a thickness of the first barrier layer and a ratio of a thickness of the second treatment layer to a thickness of the second barrier layer range from 0.03 to 0.2.
Type:
Grant
Filed:
November 15, 2019
Date of Patent:
November 21, 2023
Assignee:
Industrial Technology Research Institute
Abstract: Interaction of acoustic waves in a piezoelectric-semiconductor resonant cavity with the charge carriers in the semiconductor layer can be directed toward amplification of the acoustic waves; such amplification scheme can be applied in building unilateral amplifiers, zero loss filters, oscillators, high detection range circuit-less wireless sensors, isolators, duplexers, circulators and other acoustic devices. An apparatus for acoustoelectric amplification is described. The apparatus includes a semiconductor layer and a thin piezoelectric layer bonded (or deposited) onto the semiconductor layer forming an acoustic cavity. Two or more tethers forming a current conduction path through the semiconductor layer and two or more access pads to silicon are positioned on two ends of the acoustic cavity and configured to inject a DC current in the semiconductor layer.
Type:
Grant
Filed:
July 20, 2020
Date of Patent:
November 21, 2023
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A system may forecast a plurality of workload measurements for a database management system (DBMS) at respective times based on a workload model. The system may determine, based on the forecasted workload measurements, configuration parameter sets optimized for the DBMS at the respective times. The system may generate a reconfiguration plan. The system may determine performance that would result from reconfiguring nodes of the DBMS with the configurations parameter sets. The system may select a reconfiguration plan in response to the performance satisfying a fitness criterion. The system may cause, at the reconfiguration times, the nodes to begin reconfiguration with the configuration parameter sets included in the selected reconfiguration plan.
Type:
Grant
Filed:
September 6, 2022
Date of Patent:
November 21, 2023
Assignee:
Purdue Research Foundation
Inventors:
Saurabh Bagchi, Somali Chaterji, Ashraf Mahgoub, Paul Curtis Wood
Abstract: A steerable endovascular catheter which can be used and for diagnosis and endovascular treatment of vascular diseases. Methods of diagnosis and endovascular treatment comprising steering the catheter through vasculature of a patient.
Type:
Grant
Filed:
February 19, 2020
Date of Patent:
November 21, 2023
Assignees:
National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
Abstract: A method for localization of a drone within a building, the method may include (a) detecting, by an acoustic detection unit of the drone, sounds generated by a propulsion unit of the drone while the drone is located within the building; and (b) determining, by a processing unit of the drone, the location of the drone within the building, based on the sounds and on building acoustic information regarding sounds detected at different portions of the building.
Type:
Application
Filed:
May 11, 2023
Publication date:
November 16, 2023
Applicant:
Technion Research & Development Foundation Limited
Abstract: Disclosed herein are a method and apparatus of broadcast gateway signaling for channel bonding. The apparatus for broadcast gateway signaling includes an input formatting unit configured to generate baseband packets corresponding to channel bonding; and a stream partitioner configured to allocate the baseband packets to two or more RF channels of the channel bonding for generating an outer tunnel data stream, the outer tunnel data stream generated in different ways according to a plurality of operation modes for the channel bonding.
Type:
Application
Filed:
July 18, 2023
Publication date:
November 16, 2023
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Jae-Young LEE, Soon-Choul KIM, Sung-Ik PARK, Heung-Mook KIM
Abstract: A method and an apparatus for equipment anomaly detection are provided. In the method, multiple signals of an equipment during normal operation or appearance images of the equipment when an appearance is not damaged are acquired in advance by using a data acquisition device to train a machine learning model stored in a storage device. A real-time signal of the equipment during a current operation or a current image of the appearance of the equipment is acquired by using the data acquisition device, and input to the trained machine learning model to output a detection result indicating a current operation state of the equipment or a current state of the appearance of the equipment.
Type:
Application
Filed:
February 23, 2023
Publication date:
November 16, 2023
Applicant:
Industrial Technology Research Institute
Inventors:
Po-Han Chang, An-Chun Luo, Tien I Kao, Ming-Ji Dai, Yi-Jen Lin, Po-Huan Chou