Patents Assigned to Research
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Publication number: 20230365950Abstract: The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a SIN CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing SIN CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.Type: ApplicationFiled: February 8, 2023Publication date: November 16, 2023Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology, University of Iowa Research FoundationInventors: Feng ZHANG, Beverly DAVIDSON, Chie-Yu LIN, Edgardo RODRIGUEZ
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Publication number: 20230368810Abstract: The disclosure relates to a voice signal analysis method and device and a chip design method and device. The voice signal analysis method includes: in a first updating gradient, training a resolution recovery model by using first voice training data meeting a same grouping condition in multiple mission sets; in a second updating gradient, training the resolution recovery model by interleavingly using second voice training data meeting different grouping conditions in the mission sets; iteratively executing the first and second updating gradients to set an initial model parameter of the resolution recovery model; and recovering a high-resolution snore signal from a low-resolution snore signal by using the resolution recovery model. The low-resolution snore signal has a lower resolution than the high-resolution snore signal.Type: ApplicationFiled: June 27, 2022Publication date: November 16, 2023Applicant: Industrial Technology Research InstituteInventors: Liang-Hsuan Tai, Hong-Yu Chen, Yen-Ting Wu, Ting-Yu Wang
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Publication number: 20230366813Abstract: Various embodiments may relate to a gas cell. The gas cell may include a chamber body. The gas cell may also include a chamber lid cooperating with the chamber body to form a space. The gas cell may further include an infrared source provided in a through hole of the chamber lid such that the infrared source extends through a thickness of the chamber lid. The gas cell may additionally include a detector provided in a through hole of the chamber body. The gas cell may further include an optical chip arranged within the space such that the optical chip is between the infrared source and the detector. The gas cell may also include three O-rings.Type: ApplicationFiled: July 26, 2021Publication date: November 16, 2023Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Weiguo CHEN, Lennon Yao Ting LEE
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Publication number: 20230367553Abstract: Disclosed herein are an apparatus and method for a multiplication operation based on an outer product. The apparatus may include first internal calculators, each of which generates an intermediate accumulation value by performing a Multiply-Accumulate (MAC) operation, second internal calculators, each of which generates a chunking accumulation value using the intermediate accumulation value, and accumulation data transmission paths for enabling the output of any one of the first internal calculators to be input to any one of the second internal calculators.Type: ApplicationFiled: May 15, 2023Publication date: November 16, 2023Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventor: Hye-Ji KIM
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Publication number: 20230370825Abstract: A method of performing dynamic edge application server (EAS) instantiation triggering and an apparatus for performing the method are provided. The method of performing dynamic EAS triggering includes triggering dynamic EAS instantiation in response to an EAS discovery subscription request, transmitting a report on a need of instantiation of a target EAS, and transmitting a result of the target EAS instantiation to an edge enabler server (EES) that transmits the EAS discovery subscription request.Type: ApplicationFiled: May 9, 2023Publication date: November 16, 2023Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventor: Seung-Ik LEE
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Publication number: 20230366711Abstract: A method for estimating stream flow data of a channel includes steps of acquiring direct measurement of an index velocity of the channel, acquiring stage measurements for the channel for use in determining slope of a free surface, and applying a data-driven model combining the index velocity and a continuous slope-area method which uses the slope of the free surface to estimate stream flow data of the channel without using conventional rating curves. The direct measurement of the index velocity and the stage measurements may be received at a computing device executing instructions for applying the data-driven model.Type: ApplicationFiled: May 8, 2023Publication date: November 16, 2023Applicant: University of Iowa Research FoundationInventor: Marian Muste
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Publication number: 20230370634Abstract: The image decoding method according to the present invention comprises the steps of: determining the availability of a block adjacent to a current block; configuring a merge candidate list for the current block on the basis of the result of the determined availability; and performing motion compensation for the current block on the basis of the merge candidate list, wherein the step of determining availability comprises the steps of inducing block availability information on the adjacent block and inducing the availability of motion information on the adjacent block, and the step of determining the availability of the adjacent block is such that when there is more than one adjacent block, the availability of adjacent blocks can be determined in accordance with a predetermined order restriction.Type: ApplicationFiled: July 5, 2023Publication date: November 16, 2023Applicants: Electronics and Telecommunications Research Institute, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITYInventors: Hui Yong KIM, Sung Chang LIM, Jin Soo CHOI, Jin woong KIM, Gwang Hoon PARK, Kyung Yong KIM
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Publication number: 20230368916Abstract: There is provided a computer implemented method of diagnosing a medical state associated with a neuro-psychiatric disorder in a subject, comprising: receiving a plurality of EEG datasets, each respective EEG dataset from a respective EEG electrode of a plurality of EEG electrodes monitoring a head of the subject, clustering the plurality of EEG datasets into a plurality of clusters, computing a p-adic representation of the plurality of clusters, extracting a quantum potential value from p-adic representation of the plurality of clusters, and diagnosing the medical state associated with the neuro-psychiatric disorder according to the quantum potential relative to a threshold that separates between presence of the medical state and non-presence of the medical state.Type: ApplicationFiled: September 23, 2021Publication date: November 16, 2023Applicants: Ramot at Tel-Aviv University Ltd., Mor Research Applications Ltd.Inventors: Oded SHOR, Felix BENNINGER, Andrei KHRENNIKOV
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Publication number: 20230366031Abstract: The present disclosure provides a multiplexed amplification reaction kit for identifying a subject suffering from a malignancy sensitive to treatment with an inhibitor of the Wnt signaling pathway, comprising a primer pair capable of amplifying a PTPRK(e13)-RSPO3(e2) R-Spondin gene-fusion. Also disclosed is a method of identifying sensitivity to an inhibitor of Wnt signaling in a subject suffering from a malignancy, comprising detecting the PTPRK(e13)-RSPO3(e2) R-Spondin gene-fusion with a primer pair.Type: ApplicationFiled: April 6, 2023Publication date: November 16, 2023Applicant: Agency for Science, Technology and ResearchInventors: Bong Hwa GAN, Masafumi INOUE, Veronica DIERMAYR
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Publication number: 20230370632Abstract: The image decoding method according to the present invention comprises the steps of: determining the availability of a block adjacent to a current block; configuring a merge candidate list for the current block on the basis of the result of the determined availability; and performing motion compensation for the current block on the basis of the merge candidate list, wherein the step of determining availability comprises the steps of inducing block availability information on the adjacent block and inducing the availability of motion information on the adjacent block, and the step of determining the availability of the adjacent block is such that when there is more than one adjacent block, the availability of adjacent blocks can be determined in accordance with a predetermined order restriction.Type: ApplicationFiled: July 5, 2023Publication date: November 16, 2023Applicants: Electronics and Telecommunications Research Institute, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITYInventors: Hui Yong KIM, Sung Chang LIM, Jin Soo CHOI, Jin Woong KIM, Gwang Hoon PARK, Kyung Yong KIM
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Publication number: 20230364395Abstract: The present disclosure generally relates to systems and methods of use for draining cerebrospinal fluid (CSF) from a brain or a spinal canal in a subject, for example, to treat hydrocephalus or other conditions. In some embodiments, the disclosure relates to a device comprising a flow controller positioned within a conduit that allows CSF to flow through the conduit from a first end to a second end. This may allow the CSF to drain, for example, from an intradural space (such as a thecal sac) into, for example, a paraspinal space, paraspinal vein or other venous space, or peritoneal cavity. A variety of methods may be used to hold or anchor the device in place, for example, an expansion apparatus. In some embodiments, the device can be implanted percutaneously at a location along or within a subject's spinal column, thus reducing the need for surgery, general anesthesia, and hospitalizations.Type: ApplicationFiled: April 27, 2023Publication date: November 16, 2023Applicant: Mayo Foundation for Medical Education and ResearchInventors: Fredric B. Meyer, Mohamed Bydon
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Publication number: 20230365168Abstract: An energy dissipation device is shown in connection with its implementation in train couplers. The energy dissipation device comprises axially compressible, irreversibly deforming steel elements arranged in a housing and axially pre-tensioned between a compression means and a counter-pressure means. In case of an impact, the compression means is moving in sliding contact with the inside wall of the housing to provide axial compression of the energy absorbing elements while preserving the integrity of the housing.Type: ApplicationFiled: August 25, 2021Publication date: November 16, 2023Applicant: RXD - RESEARCH EXCHANGE DEVELOPMENT ABInventor: Roger DANIELSSON
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Publication number: 20230370093Abstract: The invention relates to systems, methods, network devices, and machine-readable media for encoding an input message with robustness against noise by executing a compressing hash function on the input message, encoding an output of the hash function and the input message to generate a single combined message, executing a permutation function on the combined message, and encoding the result of the permutation function with a list-decodable code.Type: ApplicationFiled: September 28, 2021Publication date: November 16, 2023Applicant: NTT Research, Inc.Inventors: Ofer GROSSMAN, Justin HOLMGREN, Eylon YOGEV
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Publication number: 20230366741Abstract: Disclosed is a phase shift measuring device, which includes a dual mode laser including a first beat light source generating a first beating signal and a second beat light source generating a second beating signal, and that outputs a dual mode signal including the first beating signal and the second beating signal, a first splitter that receives the dual mode signal to generate a first branch signal and a second branch signal, the first branch signal and the second branch signal being including the branched first beating signal and the branched second beating signal, respectively, a phase control unit that receives the first branch signal and to generate a combined signal, a transmitting end that receives the combined signal from the phase control unit and generates a transmission signal based on the combined signal, and a receiving end.Type: ApplicationFiled: May 11, 2023Publication date: November 16, 2023Applicant: Electronics and Telecommunications Research InstituteInventors: Il Min LEE, DA HYE CHOI, Mugeon KIM, Kyung Hyun PARK, Dong Woo PARK, JUN-HWAN SHIN, Eui Su LEE
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Publication number: 20230368591Abstract: According to various embodiment of the present invention, in a diagnosis system including a sensing module that senses the state of a motor is installed in a car, disclosed are a method for determining failure of a motor in a car comprising the steps of: (a) acquiring sensed values by sensing the state variables of the motor by the sensing module; (b) extracting two or more feature values by converting the sensed values acquired by the sensing module; (c) generating two clusters which classify and include the two or more feature values based on the two or more feature values and determining a normal cluster among the two clusters; and (d) determining the state of the motor as a failure-expected state or a safe state by applying at least one classifier to the feature values included in the normal cluster.Type: ApplicationFiled: May 10, 2023Publication date: November 16, 2023Applicants: SKAIChips Co., Ltd., Research & Business Foundation SUNGKYUNKWAN UNIVERSITYInventors: Kang Yoon LEE, Dong Gyun KIM, Dae Young CHOI, Jong Wan JO, Young Gun PU
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Publication number: 20230364170Abstract: The present invention relates to a pharmaceutical composition for preventing or treating obesity or diabetes, and to a food composition and feed composition for preventing or alleviating obesity or diabetes, comprising as an active ingredient, an Acanthopanax extract, a garcinia cambogia extract, or compounds isolated therefrom. The composition has synergistic antidiabetic and antiobesity activity compared to that of using only an Acanthopanax extract, a garcinia cambogia extract, or compounds isolated therefrom. Therefore, it is possible to reduce the possibility of any side effects that may be caused by an overdose of or long-term administration of the garcinia cambogia extract and a substance isolated therefrom, and thus the composition can be very effectively utilized in the development of a therapeutic agent for diabetes or obesity.Type: ApplicationFiled: August 18, 2021Publication date: November 16, 2023Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGYInventors: Su Ui LEE, Hyung Won RYU, Mun Ock KIM, Sei Ryang OH, Doo Young KIM, Hyun Jae JANG
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Publication number: 20230364678Abstract: An alloy powder preparation method according to an embodiment comprises the steps of: forming a mixture by mixing a plurality of metal compounds; and thermally treating the mixture, wherein, in the step of thermally treating the mixture, the process temperature changes according to the particle diameter of alloy powder. In addition, the step of thermally treating the mixture proceeds through hydrogen reduction at a process temperature of 300 to 700° C.Type: ApplicationFiled: August 31, 2021Publication date: November 16, 2023Applicants: LG ELECTRONICS INC., RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITYInventors: Byungsung KIM, Seongsoo LEE, Inhwan LEE, Dongmok WHANG
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Publication number: 20230368499Abstract: The disclosure relates to a method of extracting image features based on a vision transformer, a method of performing embedding on an input image in units of patches and extracting visual features through global attention. An apparatus for extracting an image feature based on a vision transformer according to an embodiment of the disclosure includes a memory configured to store data and a processor configured to control the memory, wherein the processor is configured to perform embedding on multi-patches for an input image, extract feature maps for the embedding multi-patches, perform transformer encoding based on a neural network using the extracted feature maps, extract a feature of the input image through a final feature map extracted through the transformer encoding, and wherein the patches have different sizes.Type: ApplicationFiled: May 16, 2023Publication date: November 16, 2023Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Young Wan LEE, Jong Hee KIM, Jin Young MOON, Kang Min BAE, Yu Seok BAE, Je Seok HAM
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Publication number: 20230370309Abstract: A feed forward equalizer includes a plurality of delay circuits connected to each other in series and configured to delay input signals. A plurality of filters respectively correspond to outputs of the plurality of delay circuits, except for a reference output which is an output of a first delay circuit among the plurality of delay circuits, and the input signals. A calculator configured to sum the reference output and outputs of the plurality of filters. Each of the plurality of filters is configured to receive an output of a delay circuit corresponding thereto, among the plurality of filters, and the reference output.Type: ApplicationFiled: May 8, 2023Publication date: November 16, 2023Applicant: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATIONInventors: CHANGJAE MOON, BYUNGSUB KIM
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Publication number: 20230369359Abstract: An electronic device includes a stack of a first level having a SPAD, a second level having a quench circuit for said SPAD, and a third level having a circuit for processing data generated by said SPAD. A method for making the device includes: a) forming of the first level; b) bonding, on the first level, by molecular bonding, of a stack of layers including a semiconductor layer; and c) forming the quench circuit of the second level in the semiconductor layer.Type: ApplicationFiled: July 24, 2023Publication date: November 16, 2023Applicants: STMicroelectronics (Crolles 2) SAS, STMicroelectronics (Research & Development) LimitedInventors: Francois GUYADER, Sara PELLEGRINI, Bruce RAE
