Abstract: An adaptor for coupling a proximal portion of an elongate surgical tool to a motorized robotic surgical device, the adaptor comprising: a recess shaped and sized for receiving a proximal portion of an elongate surgical tool; one or more movers positioned to contact and move a control component of the proximal portion; and transmission coupling which couples the one or more movers to motorized transmission of the robotic surgical device.
Type:
Application
Filed:
November 26, 2020
Publication date:
November 2, 2023
Applicants:
Microbot Medical Ltd., Technion Research & Development Foundation Limited
Inventors:
Simon SHARON, Idan BOADER, Evgeny KOFMAN, Eran COHEN, Eyal MORAG, Harel GADOT, Moshe SHOHAM
Abstract: The present invention relates to a novel pyrimidine derivative and a use thereof. The pyrimidine derivative has excellent MLK3 inhibitory activity and LRRK2 inhibitory activity and thus can be utilized in a pharmaceutical composition for preventing or treating cancers, virus infectious diseases, Parkinson's disease, nonalcoholic fatty liver disease, and tuberculosis.
Type:
Application
Filed:
December 16, 2020
Publication date:
November 2, 2023
Applicant:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Abstract: A microscopic observation method configured to observe a specimen in a specimen carrier that includes the following steps: placing the specimen carrier at an observation point; obtaining a length of the specimen carrier along a movement direction, a thickness of the specimen carrier along an observation direction of a microscope objective, an observation angle of the microscope objective, and a relative distance between a lateral surface of the specimen carrier and the microscope objective along the movement direction; and adjusting an incident angle of a light beam emitted from a dark-field illumination towards the specimen carrier according to a calculation result of the length, the thickness, the observation angle, and the relative distance.
Type:
Application
Filed:
April 27, 2022
Publication date:
November 2, 2023
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventors:
Sheng-Li CHANG, Chi Shen CHANG, Chih-Cheng HSU
Abstract: The invention concerns a compound of formula (Ia) or (lb) wherein R1 is hydrogen or a methyl group; R2 is an unsubstituted or substituted alkyl group; R3 is an aryl group or a heteroaryl group, optionally substituted by one or more groups selected from halogen, alkyl or alkoxy; and, in Formula (Ia), X is CH or N and Y is NH, S or O, or, in Formula (Ib), X is NH, S or O and Y is CH or N. The invention further concerns a method of synthesizing the inventive compound, a composition comprising the inventive compound or a pharmaceutically acceptable salt thereof and bedaquiline (BDQ), an analogue of bedaquiline (BDQ) or a mixture thereof, and the use of said composition or compound for the treatment of tuberculosis.
Type:
Application
Filed:
November 26, 2020
Publication date:
November 2, 2023
Applicants:
NANYANG TECHNOLOGICAL UNIVERSITY, AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH
Inventors:
Gerhard GRUBER, Roderick Wayland BATES, Shuyi Pearly NG
Abstract: A system for coordinating use of different motion prediction models to predict a location of a mobile robot at a future point in time can include a first motion prediction model module, a second motion prediction model module, a decision module, and an actuator module. The first motion prediction model module can determine, operating a first motion prediction model, a first prediction of a location of a mobile robot at a future point in time. The second motion prediction model module can determine, operating a second motion prediction model, a second prediction of the location of the mobile robot at the future point in time. The decision module can determine an existence of a condition. The actuator module can cause, based on a determination of the existence of the condition, the mobile robot to move based on one or more of the first prediction or the second prediction.
Type:
Application
Filed:
April 29, 2022
Publication date:
November 2, 2023
Applicants:
Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
Abstract: Systems and methods are provided for lane biasing, e.g., positioning a vehicle within a current lane of travel. Lane biasing can be dependent on learned driver behaviors or other factors that may impact lane biasing, e.g., weather conditions, traffic conditions, and so on (which may also be learned). Lane biasing may result in a vehicle traveling, e.g., off the center-line of a current lane of travel, and is distinguished from conventional lane keep assist systems that merely position a vehicle in the center of a current lane of travel by default.
Type:
Application
Filed:
April 28, 2022
Publication date:
November 2, 2023
Applicants:
TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
Inventors:
GABRIELLE M. FAVREAU, Carrie G. BOBIER-TIU, Sarah M. KOEHLER, Matthew J. BROWN, Guillermo PITA GIL
Abstract: A method for fitting an odometry noise model of a vehicle is described. The method includes collecting multiple passes of sensor measurements from motion sensors of the vehicle to measure a motion sensor noise during a testing operation of the vehicle. The method also includes determining an estimated standard deviation of the motion sensor noise measured during the testing operation of the vehicle. The method further includes determining the odometry noise model of the vehicle according to the estimated standard deviation of the motion sensor noise measured during the testing operation of the vehicle. The method also includes compensating, using the odometry noise model, the motion sensor noise during normal operation of the vehicle.
Type:
Application
Filed:
April 29, 2022
Publication date:
November 2, 2023
Applicants:
TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
Abstract: An electrolyte composition, quasi-solid-state electrolyte, and lithium-ion battery employing the same are provided. The electrolyte composition includes a component (A), component (B) and component (C). The component (A) is a combination of a first polymer (A1) and a second polymer (A2), or a third polymer (A3). The first polymer (A1) has a repeating unit of Formula (I), the second polymer (A2) has a repeating unit of Formula (II), and the third polymer (A3) has a repeating unit of Formula (I) and a repeating unit of Formula (II) , wherein R1, R2, R3, R4, R5, Z1, and Z3 are as defined in the specification. The component (B) is a lithium salt and the component (C) is a solvent.
Type:
Application
Filed:
April 24, 2023
Publication date:
November 2, 2023
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: A robot controlling method applied to a robot is provided. In the method, the robot obtains a target position and a current position of a robot, obtains a target floor of a target building according to the target position, obtains an initial floor of the target building according to the current position of the robot, generates an indoor expected passable map according to the target floor and the initial floor, generates an indoor planned path according to the indoor expected passable map, the current position, and the target position, and controls the robot to move according to the indoor planned path. The method can help the robot performing tasks in a multi-floor building.
Type:
Application
Filed:
April 28, 2023
Publication date:
November 2, 2023
Applicant:
Shenzhen Pengxing Intelligent Research Co., Ltd.
Abstract: Media monitoring and measurement systems and methods are disclosed. Some embodiments of the present invention provide a media measurement system and method that utilizes audience data to enhance content identifications. Some embodiments analyze media player log data to enhance content identification. Other embodiments of the present invention analyze sample sequence data to enhance content identifications. Other embodiments analyze sequence data to enhance content identification and/or to establish channel identification. Yet other embodiments provide a system and method in which sample construction and selection parameters are adjusted based upon identification results. Yet other embodiments provide a method in which play-altering activity of an audience member is deduced from content offset values of identifications corresponding to captured samples.
Type:
Application
Filed:
December 6, 2022
Publication date:
November 2, 2023
Applicant:
Anonymous Media Research LLC
Inventors:
Jonathan S. Steuer, Christopher W. Otto
Abstract: Systems and methods are described for optimizing bounding boxes generated using point cloud information. In one example, a method for optimizing the bounding box includes the step of using an iterative closet point (ICP) algorithm to transform the bounding box using a transformation. The point cloud acts as the reference for the ICP algorithm, while the bounding box acts as the source for the ICP algorithm.
Type:
Application
Filed:
April 29, 2022
Publication date:
November 2, 2023
Applicants:
Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
Abstract: A safe landing point search device for searching for a safe landing point of an unmanned exploration device that lands on and explores a celestial body, includes a terrain map obtaining unit configured to obtain a terrain map, a contour line generating unit configured to generate contour lines based on a reference minimum height value and a height interval value by using the terrain map, a largest empty circle (LEC) searching unit configured to search for one or more LECs having a radius greater than or equal to a lower-limit radius in a contour line map including the contour lines, and a safe landing point outputting unit configured to output a safe landing point having a largest radius among the one or more LECs and transmit the safe landing point to the unmanned exploration device.
Type:
Application
Filed:
March 19, 2020
Publication date:
November 2, 2023
Applicant:
KOREA AEROSPACE RESEARCH INSTITUTE
Inventors:
Youeyun JUNG, Hyochoong BANG, Seongheon LEE
Abstract: In a method of training a binarized neural network (BNN), a binarized weight set is generated by applying a clipping function to a weight set. Output data is generated by sequentially performing a forward computation on the binarized neural network based on input data and the binarized weight set. A gradient of the weight set is generated by sequentially performing a backward computation on the binarized neural network based on loss calculated from the output data. The binarized neural network is trained by updating the weight set based on the gradient of the weight set and changing a range of the clipping function.
Type:
Application
Filed:
February 20, 2023
Publication date:
November 2, 2023
Applicant:
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Abstract: A method of a base station may comprise: receiving, from each of terminals belonging to the base station, a capability information report message related to an artificial neural network; generating artificial neural network configuration information based on capability of the base station and the capability information report message received from each of the terminals; and transmitting the generated artificial neural network configuration information to the terminals belonging to the base station.
Type:
Application
Filed:
April 27, 2023
Publication date:
November 2, 2023
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Han Jun PARK, An Seok LEE, Heesoo LEE, Yong Jin KWON, Hyun Seo PARK, Yu Ro LEE
Abstract: A method of a first terminal supporting a first radio access technology (RAT) and a second RAT may comprise: determining candidate resources by performing a resource sensing operation based on the first RAT; performing a resource selection operation based on the first RAT with respect to the candidate resources in consideration of information on resources of the second RAT; and performing sidelink (SL) communication based on the first RAT with a second terminal using resources selected by the resource selection operation based on the first RAT.
Type:
Application
Filed:
April 24, 2023
Publication date:
November 2, 2023
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Jung Hoon LEE, Cheul Soon KIM, Sung Hyun MOON
Abstract: Disclosed are compositions and methods for targeted treatment of cancer, such as HPV-associated cancer. In particular, modified T cell receptor (TCR) T cells are disclosed that can be used with adoptive cell transfer to target and kill cancer cells with reduced antigen escape. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with HPV-associated cancer that involves adoptive transfer of the disclosed TCR-T cells.
Type:
Application
Filed:
March 22, 2021
Publication date:
November 2, 2023
Applicant:
THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH
Inventors:
Jacqueline BURROWS, Kunal H. BHATT, Rajiv KHANNA
Abstract: Provided herein are compounds that inhibit phosphodiesterase 5 (PDE5) and methods of use thereof. Also provided are pharmaceutical compositions and medicaments that include the compounds described herein as well as methods of treating gastrointestinal diseases and disorders such as intestinal cancers and inflammatory bowel disease.
Type:
Application
Filed:
May 20, 2021
Publication date:
November 2, 2023
Applicant:
AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.
Abstract: A method of predicting the responsiveness of a subject with cancer to treatment with a modulator of the HER signalling pathway, wherein the method comprises detecting the level of expression of EGR4-S in a sample of the subject, wherein the subject is likely to be responsive to treatment with the modulator of the HER signalling pathway if EGR4-S expression is at or above a predetermined level in the sample of the subject, and wherein the subject is likely to be resistant to treatment with the modulator of the HER signalling pathway if EGR4-S expression is at or below a predetermined level in the sample of the subject.
Type:
Application
Filed:
July 21, 2021
Publication date:
November 2, 2023
Applicant:
PROMETTRE CANCER RESEARCH CO LTD
Inventors:
Chau Hoang NGUYEN, John Timothy PRICE, Jeremy DRAKE
Abstract: The present invention concerns methods of diagnosing and/or prognostication of non-alcoholic fatty liver disease (NAFLD) or alcohol-related fatty liver disease (ARLD) in a subject, wherein said methods comprise detecting somatic mutations in DNA, RNA and/or protein that confer a selective advantage on one or more liver cells of the subject. The present invention also provides methods for identifying subjects suffering from NAFLD or ARLD who would benefit from treatment with a therapeutic agent and/or identifying subjects suffering from NAFLD or ARLD who would benefit from increased disease monitoring. The present invention also provides therapeutic agents that find utility in the treatment of NAFLD or ARLD.
Type:
Application
Filed:
September 23, 2021
Publication date:
November 2, 2023
Applicants:
Cambridge Enterprise Limited, Genome Research Limited
Inventors:
Matthew Hoare, Peter Campbell, Stanley NG
Abstract: The present disclosure discloses a method for impurity removal and treatment in the recycling process of scrap positive electrode materials of lithium batteries.
Type:
Application
Filed:
May 25, 2023
Publication date:
November 2, 2023
Applicant:
SICHUAN ENERGY INTERNET RESEARCH INSTITUTE, TSINGHUA UNIVERSITY