Patents Assigned to Research
  • BIOMARKERS
    Publication number: 20230348983
    Abstract: The present invention concerns methods of diagnosing and/or prognostication of non-alcoholic fatty liver disease (NAFLD) or alcohol-related fatty liver disease (ARLD) in a subject, wherein said methods comprise detecting somatic mutations in DNA, RNA and/or protein that confer a selective advantage on one or more liver cells of the subject. The present invention also provides methods for identifying subjects suffering from NAFLD or ARLD who would benefit from treatment with a therapeutic agent and/or identifying subjects suffering from NAFLD or ARLD who would benefit from increased disease monitoring. The present invention also provides therapeutic agents that find utility in the treatment of NAFLD or ARLD.
    Type: Application
    Filed: September 23, 2021
    Publication date: November 2, 2023
    Applicants: Cambridge Enterprise Limited, Genome Research Limited
    Inventors: Matthew Hoare, Peter Campbell, Stanley NG
  • METHODS FOR IMPURITY REMOVAL AND TREATMENT IN RECYCLING PROCESS OF SCRAP POSITIVE ELECTRODE MATERIALS OF LITHIUM BATTERIES
    Publication number: 20230352756
    Abstract: The present disclosure discloses a method for impurity removal and treatment in the recycling process of scrap positive electrode materials of lithium batteries.
    Type: Application
    Filed: May 25, 2023
    Publication date: November 2, 2023
    Applicant: SICHUAN ENERGY INTERNET RESEARCH INSTITUTE, TSINGHUA UNIVERSITY
    Inventors: Joey Chung-Yen JUNG, Jiujun ZHANG, Linshan DAI, Pang-Chieh SUI, Yifang SHI
  • SYSTEMS AND METHODS FOR SIMULATING CHANGE DETECTION DATA
    Publication number: 20230349716
    Abstract: System, methods, and other embodiments described herein relate to simulating change detection data. In one embodiment, a method includes converting features from a standard-definition (SD) map into high-definition (HD) map features. The method includes generating modified map features based upon the HD map features. The method includes training a machine learning model based upon the HD map features and the modified map features. The machine learning model is configured to detect a change between data from an HD map corresponding to an environment and sensor data generated by a vehicle in the environment.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 2, 2023
    Applicants: Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
    Inventors: Xipeng Wang, Ryan M. Wiesenberg
  • COMPOSITIONS AND METHODS FOR TARGETING HPV-INFECTED CELLS
    Publication number: 20230348558
    Abstract: Disclosed are compositions and methods for targeted treatment of cancer, such as HPV-associated cancer. In particular, modified T cell receptor (TCR) T cells are disclosed that can be used with adoptive cell transfer to target and kill cancer cells with reduced antigen escape. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with HPV-associated cancer that involves adoptive transfer of the disclosed TCR-T cells.
    Type: Application
    Filed: March 22, 2021
    Publication date: November 2, 2023
    Applicant: THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH
    Inventors: Jacqueline BURROWS, Kunal H. BHATT, Rajiv KHANNA
  • GRAPHICS PROCESSOR UNIT WITH OPPORTUNISTIC INTER-PATH RECONVERGENCE
    Publication number: 20230350675
    Abstract: A graphics processing unit and methods for comping and executing instructions with opportunistic inter-path reconvergence are provided. An single instruction multiple thread (SIMT) stack of graphics processing unit may store data entries, each data entry comprising an operand mask. The operand mask may include bits corresponding to threads of a warp. The graphics processing unit core may access an instruction for an entry on the SIMT stack. Each of the threads may execute the instruction using either a first set of operands or a second set of operands depending on the corresponding bits of the operand mask.
    Type: Application
    Filed: June 30, 2023
    Publication date: November 2, 2023
    Applicant: Purdue Research Foundation
    Inventors: Milind Kulkarni, Jad Hbeika
  • CYCLODEXTRIN DERIVATIVES IN THE TREATMENT OR PREVENTION OF LYSOSOMAL NEURODEGENERATIVE DISEASES
    Publication number: 20230346825
    Abstract: The present invention generally relates to use of single isomer chemically modified cyclodextrins, namely, S-(carboxyalkyl)-thio-cyclodextrin salts in medication used for the prevention or treatment of lysosomal storage diseases. More particularly, the present invention relates to isomer-pure, single isomer hexakis-S-(carboxyalkyl)-hexathio-alpha-cyclodextrin sodium salts, heptakis-S-(carboxyalkyl)-heptathio-beta-cyclodextrin sodium salts and octakis-S-(carboxyalkyl)-octathio-gamma-cyclodextrin sodium salts in medication used for the prevention or treatment of lysosomal storage diseases.
    Type: Application
    Filed: September 29, 2021
    Publication date: November 2, 2023
    Applicant: CYCLOLAB CYCLODEXTRIN RESEARCH AND DEVELOPMENT LABORATORY LTD.
    Inventors: István Puskás, Abdula KURKAYEV
  • CHIMERIC ANTIGEN RECEPTORS (CARS) TARGETING NATURAL KILLER CELLS
    Publication number: 20230348854
    Abstract: The current disclosure provides chimeric antigen receptors (CARs) that bind a natural killer (NK) cell surface marker, resulting in destruction of the bound NK cell. The NK cell surface markers include an activating NK cell receptor, and an inhibitory NK cell receptor. Cells that are genetically modified to express these CARs and uses of the CAR modified cells are also described.
    Type: Application
    Filed: May 7, 2021
    Publication date: November 2, 2023
    Applicant: Seattle Children's Hospital d/b/a Seattle Children's Research Institute
    Inventors: Thor Wagner, Floriane Ngako Kameni
  • EXPRESSION VECTOR FOR USE IN METHANOTROPH
    Publication number: 20230348917
    Abstract: Disclosed are a vector comprising a first expression cassette comprising a DmpR ribosomal binding site as a transcriptional regulator and a promoter operably linked thereto; and a second expression cassette comprising a sequence encoding a target polypeptide, a ribosomal binding site, and a Po promoter operably linked thereto, and a methanotroph transformed by the vector.
    Type: Application
    Filed: March 24, 2023
    Publication date: November 2, 2023
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Seung Goo LEE, Dae Hee Lee, Hye Won Lee, Seong Keun Kim, Ji In Baek, Tae Hyun Kim, So Hyung Oh
  • SECURITY POLICY TRANSLATION IN INTERFACE TO NETWORK SECURITY FUNCTIONS
    Publication number: 20230353598
    Abstract: Disclosed is a method in which a security controller translates a security policy for Interface to Network Security Functions (I2NSF), the method including: extracting data from a higher-level policy received from an I2NSF user; converting the extracted data into a capability of a target network security function (NSF) of the security policy by referring to mapping information between elements of a high-level data model and elements of a low-level data model; and generating a lower-level policy to execute the capability of the NSF.
    Type: Application
    Filed: December 27, 2022
    Publication date: November 2, 2023
    Applicant: Research & Business Foundation SUNGKYUNKWAN UNIVERSITY
    Inventors: Jaehoon JEONG, Patrick LINGGA, Jeonghyeon KIM
  • METHOD FOR GENERATING RADAR PROJECTIONS TO REPRESENT ANGULAR UNCERTAINTY
    Publication number: 20230350050
    Abstract: The disclosure generally relates to methods for gathering radar measurements, wherein the radar measurements includes one or more angular uncertainties, generating a two dimensional radar uncertainty cloud, wherein the radar uncertainty cloud includes one or more shaded regions that each represent an angular uncertainty, capturing image data, wherein the image data includes one or more targets within a region of interest, and fusing the two dimensional radar uncertainty cloud with the image data to overlay the one or more regions of uncertainty over a target.
    Type: Application
    Filed: April 27, 2022
    Publication date: November 2, 2023
    Applicants: TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Charles Christopher Ochoa, Arjun Bhargava, Chao Fang, Kun-Hsin Chen, Kuan-Hui Lee
  • PARKED CAR CLASSIFICATION BASED ON A VELOCITY ESTIMATION
    Publication number: 20230351766
    Abstract: A method controlling an ego vehicle in an environment includes determining, via a flow model of a parked vehicle recognition system, a flow between a first representation of the environment and a second representation of the environment. The method also includes determining, via a velocity model of the parked vehicle recognition system, a velocity of a vehicle in the environment based on the flow. The method further includes determining, via a parked vehicle classification model of the parked vehicle recognition system, the vehicle is parked based on the velocity of the vehicle and one or more of features associated with the vehicle and/or the environment. The method still further includes planning a trajectory of the ego vehicle based on determining the vehicle is parked.
    Type: Application
    Filed: April 28, 2022
    Publication date: November 2, 2023
    Applicants: TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Kuan-Hui LEE, Charles Christopher OCHOA, Arjun BHARGAVA, Chao FANG
  • DIGITAL FEEDBACK BASED ADAPTIVE DELAY TIME CONTROL METHOD AND APPARATUS FOR HIGH EFFICIENCY ACTIVE RECTIFIER
    Publication number: 20230353031
    Abstract: Disclosed are a method and an apparatus of digital feedback based adaptive delay time control for a high efficiency active rectifier. According to the present invention, provided is an apparatus for digital feedback based adaptive delay time control, which adaptively compensates a driving delay of a switch by controlling a time of a delay circuit through a digital feedback-based compensation technique, and operate the switch at an appropriate timing in spite of changes in operation environments such as an input voltage and a load to increase the efficiency of an AC-DC rectifier.
    Type: Application
    Filed: March 27, 2023
    Publication date: November 2, 2023
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Hyung Min LEE, Ji San AHN
  • HAND FRICTION ESTIMATION FOR ESTIMATING GUARDIAN USER OR CHAUFFEUR SAFETY DRIVER PREFERENCE
    Publication number: 20230347919
    Abstract: The disclosure generally describes a system and method for determining a preferred steering wheel rate in autonomous and semi-autonomous driving systems that includes measuring a torque applied to the steering wheel by a driver during an autonomous driving mode, measuring the steering wheel position, measuring the steering wheel rate of rotation, wherein the steering position and rate of rotation are measured at the time when the torque was applied to the steering wheel, determining a preferred steering wheel rate of rotation, and adjusting the steering wheel rate of rotation during an autonomous driving maneuver to include the preferred steering wheel rate.
    Type: Application
    Filed: April 28, 2022
    Publication date: November 2, 2023
    Applicants: TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: MANUEL AHUMADA, Sarah M. Koehler, Matthew J. Brown
  • DEVICES, SYSTEMS, AND METHODS FOR CONTROLLING DEPLOYMENT OF A MEDICAL DEVICE
    Publication number: 20230346543
    Abstract: A delivery/deployment system for delivering an implantable device within an implantable device housing and for deploying the implantable device from the implantable device housing. A stylet may be used to longitudinally advance or retract the implantable device with respect to the implantable device housing, such as to extend and deploy the implantable device from the implantable device housing. The delivery/deployment system has an implantable-device-extension-limiter arrangement configured to limit the distance which the implantable device may be extended from the implantable device housing. The delivery/deployment system optionally also has an implantable-device-rotation-limiter arrangement configured to limit rotation of the implantable device with respect to the implantable device housing.
    Type: Application
    Filed: April 27, 2023
    Publication date: November 2, 2023
    Applicants: BOSTON SCIENTIFIC SCIMED, INC., MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Mitchell Nelson, Troy Anthony Giese, Joel T. Eggert, Jason John Matteson, JR., Christopher J. Koudela, Dana Sachs
  • METHOD FOR BEAM SEARCH AND MANAGEMENT OF MOVING BACKHAUL SYSTEM, AND MOVING BACKHAUL HUB USING THE SAME
    Publication number: 20230353222
    Abstract: A beam management method performed by a moving backhaul hub may comprise: calculating, based on location information at a first time, a first separation distance between the moving backhaul hub and a moving backhaul terminal, a first azimuth angle to which a beam of the moving backhaul hub is directed, and a first elevation angle in which the beam of the moving backhaul hub is directed; determining an operation mode of the moving backhaul terminal using the first separation distance, the first azimuth angle, and/or the first elevation angle; determining whether to transmit a beam search command message to the moving backhaul terminal based on the operation mode of the moving backhaul terminal; and transmitting signals to the moving backhaul terminal in consideration of the operation mode when the beam search command message is transmitted to the moving backhaul terminal.
    Type: Application
    Filed: April 21, 2023
    Publication date: November 2, 2023
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Kyung Yeol SOHN
  • Self-Calibration for Decoration Based Sensor Fusion Method
    Publication number: 20230351768
    Abstract: A method for self-calibrating alignment between image data and point cloud data utilizing a machine learning model includes receiving, with an electronic control unit, image data from a vision sensor and point cloud data from a depth sensor, implementing, with the electronic control unit, a machine learning model trained to: align the point cloud data and the image data based on a current calibration, detect a difference in alignment of the point cloud data and the image data, adjust the current calibration based on the difference in alignment, and output a calibrated embedding feature map based on adjustments to the current calibration.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 2, 2023
    Applicants: Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
    Inventors: Jie Li, Vitor Guizilini, Adrien Gaidon
  • PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR
    Publication number: 20230346960
    Abstract: The present disclosure provides pro-angiogenic proteoglycan mimetics that can provide a provisional, pro-angiogenic scaffold to support tissue regeneration while limiting systemic exposure to VEGF activity. These mimetics can protect a collagen matrix from rapid degradation, and in conjunction with EPCs promote angiogenesis in order to accelerate ischemic wound healing. For example, the provided compounds can be delivered from the end of a catheter following balloon angioplasty to coat the collagen exposed areas, prevent platelet binding and thrombosis, support capture of EPCs from blood to facilitate reendothelialization, and reduce late-lumen loss (neointimal hyperplasia).
    Type: Application
    Filed: February 14, 2023
    Publication date: November 2, 2023
    Applicants: The Regents of the University of California, Purdue Research Foundation
    Inventors: Alyssa Panitch, Emily Michelle Misnick, Jenny B. Lin, Kit S. Lam, Ruiwu Liu, Dake Hao, Aijun Wang
  • SYSTEM AND METHOD FOR ADJUSTING BOUNDING BOX DIMENSIONS
    Publication number: 20230350034
    Abstract: Systems and methods for adjusting the dimensions of point clouds are described herein. In one example, a system includes a processor and a memory having instructions that, when executed by the processor, cause the processor to generate a bounding box using a point cloud generated by a sensor and adjust a dimension of the bounding box based on a magnitude of a viewing angle of a side of the bounding box with respect to the sensor.
    Type: Application
    Filed: April 28, 2022
    Publication date: November 2, 2023
    Applicants: Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
    Inventor: Jacopo Serafin
  • DEVICE AND METHOD FOR SYNCHRONIZING DATA IN REAL TIME BETWEEN DATA HUBS
    Publication number: 20230353634
    Abstract: Provided are a device and method for synchronizing data between hubs in real time. The method includes verifying a session interworking environment, deriving session negotiation candidates, generating a session negotiation protocol message, transmitting a session negotiation request signal including the generated session negotiation protocol message to a second data hub, receiving a session negotiation settlement signal corresponding to the session negotiation request signal from the second data hub, generating a session module on the basis of the session negotiation settlement signal, and transmitting a session negotiation settlement signal to the second data hub.
    Type: Application
    Filed: April 27, 2023
    Publication date: November 2, 2023
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: Hee Sun WON, Chan Hyun YOUN, Seong Hwan KIM, Ji Hwan KIM, Eun Ju YANG, Jeong Won LEE
  • SYSTEMS AND METHODS FOR DETECTING A REFLECTION ARTIFACT IN A POINT CLOUD
    Publication number: 20230351765
    Abstract: Systems, methods, and other embodiments described herein relate to detecting reflection artifacts in a point cloud. In one embodiment, a method includes generating a first convex hull for defining an outline of a first cluster of points in a depth image and generating a second convex hull for defining an outline of a second cluster of points in the depth image. The first cluster of points originates from a point cloud and the second cluster of points originates from the point cloud. The method includes determining whether the second cluster of points is a reflection artifact based on identifying if a portion of the second convex hull is enclosed in the first convex hull and a range of the second convex hull is larger than a range of the first convex hull.
    Type: Application
    Filed: April 28, 2022
    Publication date: November 2, 2023
    Applicants: Toyota Research Institute, Inc., Toyota Jidosha Kabushiki Kaisha
    Inventors: Jonathan A. Daudelin, Jacopo Serafin, Sachithra Hemachandra