Abstract: The invention relates to novel arylpyrazoles of the formula (I):
wherein R1, R3, R7, R14, R15, R16, and R17 are as defined in the description, and to their use as pesticides.
Type:
Grant
Filed:
September 20, 2000
Date of Patent:
May 28, 2002
Assignee:
Rhone-Poulenc Inc.
Inventors:
Jamin Huang, Patrick Doyle Lowder, Nicholas Charles Ray, David W. Hawkins
Abstract: The present invention relates to mixtures which can be isolated from grains of Eugenis Jambolana Lamarck, the preparation of such mixtures, the medicaments containing said mixtures or constituents of said mixtures, and the use of these mixtures and constituents for the preparation of a medicament.
Type:
Application
Filed:
December 12, 2000
Publication date:
May 2, 2002
Applicant:
RHONE-POULENC RORER S.A. and INSTITUT MALGACHE DE RECHERCHES APPLIQUEES
Inventors:
Albert Rakoto Ratsimamanga, Suzanne Rakoto Ratsimamanga, Philippe Rasoanaivo, Jean Leboul, Jean Provost, Daniel Reisdorf
Abstract: The present invention relates to optically active diphosphines. It is also targeted at their preparation according to a process for the resolution of the racemic mixture of the said phosphines to optically active isomers. The subject of the invention is new optically active bis[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] diphosphines and a process for resolving the racemic bis[1-phospha-2,3-diphenyl-4,5-dimethylnorbornadiene] mixture which comprises reacting it with a palladium or platinum complex as chiral auxiliary in an organic solvent, thus forming diastereoisomer complexes, and then resolving the said optically pure complexes. The invention also relates to new optically active metal complexes comprising the said phosphines and to their use in a process for the preparation of optically active carboxylic acids and/or derivatives according to a process for the hydrogenation of &agr;,&bgr;-unsaturated carboxylic acids and/or derivatives.
Type:
Grant
Filed:
February 4, 2000
Date of Patent:
April 30, 2002
Assignee:
Rhone-Poulenc Chimie
Inventors:
Francois Mathey, Frédéric Robin, Francois Mercier, Michel Spagnol
Abstract: The present invention relates to a method for supplying bioavailable methionine to a cow which comprises supplying to the cow an ester of methionine or methionine amide and/or an ester of the hydroxy analogue of methionine or a salt thereof.
Type:
Grant
Filed:
February 28, 2001
Date of Patent:
April 16, 2002
Assignee:
Rhone-Poulenc Animal Nutrition
Inventors:
Jean-Claude Robert, Robert Bennett, Georges Gros
Abstract: N-Phenylpyrazole derivatives of the formula:
wherein
R1 represents optionally halogenated alkyl;
R2 represents halogen, cyano, nitro, cycloalkyl, alkenyl, thiocyanato, optionally alkyl substituted sulphamoyl, optionally alkyl substituted carbamoyl, alkoxycarbonyl, alkanoyl or optionally halogenated alkyl; and R3 represents a hydrogen atom or a group N″R′″ or a variety of other groupings. These compounds possess arthropodicidal, plant nematocidal, anthelmintic and anti-protozoal properties; their preparation, compositions containing them and their use are described.
Type:
Grant
Filed:
July 16, 1999
Date of Patent:
April 16, 2002
Assignee:
Rhone-Poulenc Agriculture Ltd.
Inventors:
Leslie Roy Hatton, Ian George Buntain, David William Hawkins, Edgar William Parnell, Christopher John Pearson, David Alan Roberts
Abstract: Synergistic fungicidal composition comprising propamocarb and a derivative of phosphorous acid; and
process for the curative or preventative control of phytopathogenic fungi by use of such a composition.
Type:
Grant
Filed:
February 15, 2000
Date of Patent:
March 19, 2002
Assignee:
Rhone-Poulenc Agro
Inventors:
Joëlle Donnadieu, Patrice Duvert, Richard Mercer
Abstract: Recombinant adenoviruses comprising a heterologous DNA sequence coding for glial-derived neurotrophic factor (GDNF), preparation thereof, and use thereof for treating and/or preventing degenerative neurological diseases.
Type:
Application
Filed:
August 1, 1997
Publication date:
March 14, 2002
Applicant:
RHONE-POULENC RORER S.A.
Inventors:
PHILIPPE HORELLOU, JACQUES MALLET, MICHEL PERRICAUDET, FREDERIC REVAH, EMMANUELLE VIGNE
Abstract: Linoleic acid is converted into &ggr;-linolenic acid by the enzyme &Dgr;6-desaturase. The present invention is directed to isolated nucleic acids comprising the &Dgr;6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the &Dgr;6-desaturase gene. The present invention provides recombinant constructions comprising the &Dgr;6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.
Abstract: The invention relates to novel 1-arylpyrazole oxime derivatives, of general formula (I) or (I bis)
These compounds are found to be generally safe systemic insecticides for control of arthropod, nematode, helminth or protozoan pests including compositions and derivatives thereof.
Type:
Grant
Filed:
December 12, 1997
Date of Patent:
February 26, 2002
Assignee:
Rhone-Poulenc, Inc.
Inventors:
Tai-Teh Wu, Alain Chene, David Treadway Manning, Peter Wyatt Newsome, Nicholas Charles Ray, Jennifer Lantz Phillips, Patrick Doyle Lowder
Abstract: A fungicidal composition comprising a compound A having the formula:
wherein M is an oxygen or sulphur atom, n is 0 and 1, and Y is a fluorine or chlorine atom or a methyl radical; and at least one fungicidal compound B. A method for preventing or controlling phytopathogenic fungi on crops by applying an effective and non-plant-poisonous amount of said compound on the exposed parts of the plants is also disclosed.
Abstract: Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones, processes for their preparation, fungicidal compositions containing them, and methods of using them to treat or prevent fungal disease in crops.
Type:
Grant
Filed:
October 14, 1999
Date of Patent:
February 5, 2002
Assignee:
Rhone-Poulenc, Inc.
Inventors:
Guy Lacroix, Raymond Peignier, Regis Pepin, Jean-Philippe Bascou, Gilbert Emeric, Joseph Perez, Fabrice Pinard, Christian Schmitz, Alain Gadras
Abstract: The complete cDNA cloning of two human genes previously designated flg and bek is disclosed. These genes encode for two similar but distinct surface receptors comprised of an extracellular domain with three immunoglobulin-like regions, a single transmembrane domain, and a cytoplasmic portion containing a tyrosine kinase domain with a typical kinase insert. The expression of these two cDNAs in transfected NIH-3T3 cells led to the biosynthesis of proteins of 150 kDa and 135 kDa for flg and bek respectively. Direct binding experiments with radiolabeled acidic FGF (aFGF), basic FGF (bFGF), or kFGF inhibition of binding with native growth factors, and Scatchard analysis of the binding data indicated that bek and flg bind aFGF, bFGF, or kFGF with dissociation constants of (2-15)×10−11M. The high affinity binding of three distinct growth factors to each of two different receptors represents a unique double redundancy without precedence among polypeptide growth factor/receptor interactions.
Type:
Grant
Filed:
October 14, 1994
Date of Patent:
February 5, 2002
Assignee:
Rhone Poulenc Rorer Inc.
Inventors:
Craig A. Dionne, Gregg B. Crumley, Michael C. Jaye, Joseph Schlessinger
Abstract: The present invention is directed to isolated promoter sequences from seed-specific genes, such as KNAT411. When operably linked to either the coding sequence of a heterologous gene or a sequence complementary to a native plant gene, the subject promoters direct expression of the coding sequence or complementary sequence in a plant seed, including the early embryo. The promoter sequences are useful in expression cassettes and expression vectors for the transformation of plants. Also provided are methods of directing seed-specific expression of a gene or sequence complementary to a native plant gene by introducing into a plant cell an isolated nucleic acid comprising a subject promoter operably linked to said gene or complementary sequence. Methods for activating a site-specific recombination system in the early embryo of a seed by transforming a plant with an expression cassette comprising a subject promoter operably linked to a recombinase gene are also provided.
Abstract: The invention concerns human neural progenitor cells containing introduced genetic material encoding a product of interest, and their use for the treatment of neurodegenerative diseases.
Type:
Application
Filed:
February 28, 1997
Publication date:
January 17, 2002
Applicant:
Rhone-Poulenc Rorer, S.A.
Inventors:
OLIVIER SABATE, PHILIPPE HORELLOU, MARIE-HELENE BUC-CARON, JACQUES MALLET
Abstract: An isolated DNA sequence capable of serving as regulatory element in a chimeric gene which can be used for the transformation of plants is disclosed. A chimeric gene for the transformation of plants is also disclosed. The gene comprises at least, in the direction of transcription, a promoter sequence, a transgene and a regulatory element, characterized in that the regulatory element consists of at least one intron 1 in the noncoding 5′ region of a plant histone gene allowing the expression of the protein in the zones and undergoing rapid growth. The production of transgenic plants is also disclosed.
Type:
Grant
Filed:
May 29, 1998
Date of Patent:
January 15, 2002
Assignee:
Rhone-Poulenc Agrochimie
Inventors:
Richard DeRose, Nicole Chaubet, Claude Gigot