Abstract: Phenoxyacetic acid derivatives of the formula:
wherein R1, R2, Xn and A are as defined herein, and a process for preparing the derivatives. The derivatives are used as herbicides.
Abstract: 4-Benzoylisoxazole derivatives of the formula
wherein R is H or an ester; R1 is alkyl, haloalkyl or optionally substituted cycloalkyl; R2 is halogen, optionally halogenated alkyl, alkenyl or alkynyl; alkyl substituted with one or more —OR5; —NO2, —CN, —CO2R5, —S(O)pR6, —O(CH2)mOR5, —COR5, —NR5R6, —N(R8)SOqR7, —CONR9R10 or —OR51; or optionally substituted phenyl; R3 is —S(O)qR7; X is —N(R8)—; n is 0, 1, 2, 3, or 4; R5, R51 and R6 are independently H; optionally halogenated alkyl, alkenyl or alkynyl; optionally substituted phenyl; or cycloalkyl; R7 is optionally halogenated alkyl, alkenyl or alkynyl; cycloalkyl; optionally substituted phenyl; or optionally substituted amino; R8 is H; optionally halogenated alkyl, alkenyl or alkynyl; cycloalkyl; optionally substituted phenyl; or alkoxy; m is 1, 2 or 3; p is 0, 1 or 2; q is 0 or 2; and their use as herbicides are described.
Type:
Grant
Filed:
November 1, 1995
Date of Patent:
November 27, 2001
Assignee:
Rhone-Poulenc Agriculture Limited
Inventors:
Tibor Musil, Simon Neil Pettit, Philip Henry Gaunt Smith
Abstract: Fluorocarbon compounds are synthesized by reacting a substrate hydrocarbyl compound containing at least one sp3-hybridized halophoric carbon atom bearing at least two halogen atom substituents, at least one of which is a halogen atom having an atomic number greater than that of fluorine and the at least one halophoric carbon atom being bonded to at least one chalcogen, with at least one reactant which comprises a complex of a Bronstedt base with a defined amount n of hydrofluoric acid, n being at least 3 and not greater than 20.
Abstract: Novel adenovirus-derived viral vectors, the preparation thereof, and their use in gene therapy, are disclosed. In particular, recombinant adenoviruses including an adenovirus genome wherein (i) the E1 region is inactivated, (ii) the genomic organization is modified, and (iii) optional recombination with the producing line genome generates non-viable viral particles, are disclosed.
Type:
Application
Filed:
January 26, 2001
Publication date:
November 8, 2001
Applicant:
Rhone-Poulenc Rorer S.A.
Inventors:
Patrice Yeh, Michel Perricaudet, Cecile Orsini
Abstract: Isolated DNA sequence which can serve as terminator region in a chimeric gene capable of being used for the transformation of plants
1) Chimeric gene for the transformation of plants.
2) It comprises at least, in the direction of transcription, a promoter region, a transgene and a terminator region, characterized in that the terminator region consists of at least one terminator region from a plant histone gene permitting the expression of the protein in the regions of rapid growth.
3) Production of transgenic plants.
Type:
Grant
Filed:
July 18, 1997
Date of Patent:
November 6, 2001
Assignee:
Rhone-Poulenc Agrochimie
Inventors:
Rossitza Atanassova, Richard De Rose, Georges Freyssinet, Claude Gigot, Michel Lebrun
Abstract: Novel adenovirus-derived viral vectors, the preparation thereof, and their use in gene therapy, are disclosed. In particular, recombinant adenoviruses including an adenovirus genome wherein (i) the E1 region is inactivated, (ii) the genomic organization is modified, and (iii) optional recombination with the producing line genome generates non-viable viral particles, are disclosed.
Type:
Grant
Filed:
April 22, 1997
Date of Patent:
November 6, 2001
Assignee:
Rhone-Poulenc Rorer S.A.
Inventors:
Patrice Yeh, Michel Perricaudet, Cécile Orsini
Abstract: The invention relates to a composition, in pellet form, useful for the nutritional and/or medicinal supplementation of ruminants and a method for admixing the pellets with foodstuff. The pellet contains granules of one or more active ingredients/principles protected against degradation in toe rumen and one or more binding agents capable of being solubilized, crosslinked or melted. Optionally, the pellet may also contain an unprotected active ingredient for release in the rumen. The pellet may further contain a disintegrating agent and/or filler.
Type:
Grant
Filed:
February 1, 1993
Date of Patent:
October 23, 2001
Assignee:
Rhone-Poulenc Nutrition Animale
Inventors:
Claude Annonier, Pierre Autant, Jacques Ruel, Hugues Porte, Jean-Claude Laffay, Alain Sabatier
Abstract: This invention is directed to certain physiologically active compounds of formula (I)
wherein
represents a bicyclic ring system, of about 10 to about 13 ring members, in which the ring
is an azaheterocycle, and the ring
represents an azaheteroaryl ring, or an optionally halo substituted benzene ring;
and N-oxides thereof, and their prodrugs, and pharmaceutically acceptable salts and solvates of the compounds of formula (I) and N-oxides thereof, and their prodrugs. Such compounds inhibit the production or physiological effects of TNF and inhibit cyclic AMP phosphodiesterase. The invention is also directed to pharmaceutical compositions comprising compounds of formula (I), their pharmaceutical use and methods for their preparation.
Type:
Grant
Filed:
December 18, 1998
Date of Patent:
October 16, 2001
Assignee:
Rhone-Poulenc Rorer Limited
Inventors:
Paul Joseph Cox, David John Aldous, Daniel Gerard McGarry, Christopher Hulme, John Robinson Regan, Fu-Chih Huang, Stevan Wakefield Djuric, Kevin Joseph Moriarty, Rose Mappilakunnel Mathew, Gregory Bernard Poli
Abstract: A detergent composition containing alkali-metal silicate with an average molar ratio of SiO2/M2O of 1-4.2, preferably 2.5-4.2, wherein M is an alkali metal, the composition being non-corrosive to glass, crystal, porcelain and decorative prints thereon upon repeated washing. The composition being such that when disposed in a washing medium at a normal working concentration, a protonated silicic monomer Si(OH)4 is produced in a concentration of at least 2.5×10−3 mol/liter of the washing medium.
Type:
Grant
Filed:
March 17, 1999
Date of Patent:
October 9, 2001
Assignee:
Rhone-Poulenc Chimie
Inventors:
Eric Aubay, Agnès Froute, Aude Guirauden, Daniel Joubert
Abstract: The present invention relates to mixtures which can be isolated from grains of Eugenis Jambolana Lamarck, the preparation of such mixtures, the medicaments containing said mixtures or constituents of said mixtures, and the use of these mixtures and constituents for the preparation of a medicament.
Type:
Grant
Filed:
December 12, 2000
Date of Patent:
October 9, 2001
Assignees:
Rhone-Poulenc Rorer SA, Institut Malgache DeRecherches Appliquees
Inventors:
Albert Rakoto Ratsimamanga, Suzanne Rakoto Ratsimamanga, Philippe Rasoanaivo, Jean Leboul, Jean Provost, Daniel Reisdorf
Abstract: The present invention resides in use of a recombinant adenovirus of animal origin containing a heterologous DNA sequence for the preparation of a pharmaceutical composition intended for the therapeutic and/or surgical treatment of the human body.
Type:
Grant
Filed:
November 17, 1995
Date of Patent:
September 25, 2001
Assignee:
Rhone-Poulenc Rorer SA
Inventors:
Hedi Haddada, Bernard Klonjkowski, Michel Perricaudet, Emmanuelle Vigne
Abstract: Essentially spherical precipitated silica beads, well adapted for the reinforcement of elastomeric matrices, have a mean particle size of at least 80 &mgr;m, a BET specific surface area ranging from 60 to 130 m2/g, a fill density in packed state ranging from 0.28 to 0.37, and a total pore volume ranging from 1.6 to 3.3 cm3/g.
Abstract: Compounds of formula (I):
their racemates, enantiomers, diastereoisomers and inorganic acid salts and organic acid salts thereof, processes for preparing them and the medicaments containing them are discussed.
Type:
Grant
Filed:
August 27, 1999
Date of Patent:
September 11, 2001
Assignee:
Rhone-Poulenc Rorer S.A.
Inventors:
Jean-Claude Hardy, Jean Bouquerel, Patrick Nemecek, Jean-Claude Aloup, Serge Mignani, Jean-François Peyronel
Abstract: Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix.
Type:
Grant
Filed:
June 9, 1997
Date of Patent:
September 11, 2001
Assignee:
Rhone-Poulenc Rorer S.A.
Inventors:
Joël Crouzet, Daniel Scherman, Pierre Wils
Abstract: Thermally/chemically stable and nontoxic inorganic pigments/colorants, characteristically green and well suited for the coloration of a wide variety of materials and substrates, for example, plastics, ceramics, etc., comprise at least one mixed oxide of the formula:
R2MxM′yO5
in which R is at least one element selected from among yttrium and a rare earth having an atomic number ranging from 62 to 71, inclusive, M and M′, which may be identical or different, are each at least one metallic element exhibiting at least one valence state of +2, and x and y are numbers, the sum x+y of which is equal to 2.
Abstract: A method for the stabilization of a phospholipidic composition as well as a method for the production of a stabilized phospholipidic composition comprising at least one phospholipide as well as a stabilizer are described, whereby in the claimed methods at least one phospholipide is mixed with a stabilizer on the basis of phytic acid, of a salt of the phytic acid and/or of a phytic acid derivative.