Patents Assigned to Rice University
  • Publication number: 20120213994
    Abstract: Various embodiments of the present invention pertain to x-ray absorbing compositions that comprise a carbon material associated with an x-ray absorbing material. In some embodiments, the x-ray absorbing material is selected from the group consisting of lead-based compounds, bismuth-based compounds, and combinations thereof. In some embodiments, the carbon material is selected from the group consisting of carbon nanotubes, graphenes, carbon fibers, amorphous carbons, and combinations thereof. In further embodiments, the carbon materials of the present invention may also be treated with a surfactant, an acid, polymers or combinations thereof. In some embodiments, the carbon materials of the present invention may be further associated with a metal oxide. Additional embodiments of the present invention pertain to methods of making the aforementioned x-ray absorbing compositions. Such methods generally include associating a carbon material with an x-ray absorbing material.
    Type: Application
    Filed: January 17, 2012
    Publication date: August 23, 2012
    Applicant: William Marsh Rice University
    Inventors: Huma Rahim Jafry, Andrew Ross Barron
  • Publication number: 20120208008
    Abstract: In various embodiments, the present invention provides electrically conductive and radio frequency (RF) transparent films that include a graphene layer and a substrate associated with the graphene layer. In some embodiments, the graphene layer has a thickness of less than about 100 nm. In some embodiments, the graphene layer of the film is adhesively associated with the substrate. In more specific embodiments, the graphene layer includes graphene nanoribbons that are in a disordered network. Further embodiments of the present invention pertain to methods of making the aforementioned electrically conductive and RF transparent films. Such methods generally include associating a graphene composition with a substrate to form a graphene layer on a surface of the substrate.
    Type: Application
    Filed: January 20, 2012
    Publication date: August 16, 2012
    Applicants: Lockheed Martin Corporation, William Marsh Rice University
    Inventors: James M. Tour, Vladimir Volman, Yu Zhu
  • Patent number: 8236491
    Abstract: A protein fragment complementation assay for thermophiles is provided wherein a thermophilic bacteria having a temperature-sensitive adenylate kinase is transformed with one or more vectors having sequences encoding a first test peptide operatively fused to a first portion of a thermostable adenylate and a second test peptide operatively fused to a second portion of the thermostable adenylate kinase. Association of the first and second test peptides allows association of the first and second portions of the thermostable adenylate kinase and growth of the thermophilic bacteria at a temperature greater than 70° C.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: August 7, 2012
    Assignee: William Marsh Rice University
    Inventors: Jonathan Silberg, Peter Q. Nguyen
  • Patent number: 8236525
    Abstract: A method of producing biological products using bacteria with an inactivated ptsHI and wild type err and no added glucose transport activity and which consumes nearly all glucose in the media is described. The ?ptsHI bacteria produce large quantities of recombinant protein without producing significant amounts of acetate. The bacteria grow well on standard LB broth without additional supplementation.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: August 7, 2012
    Assignee: William Marsh Rice University
    Inventors: Ka-Yiu San, George N. Bennett, Thomas Bryce Causey, Matthew Sing Wong, Steven Wu
  • Publication number: 20120197051
    Abstract: In various embodiments, the present disclosure describes processes for preparing functionalized graphene nanoribbons from carbon nanotubes. In general, the processes include exposing a plurality of carbon nanotubes to an alkali metal source in the absence of a solvent and thereafter adding an electrophile to form functionalized graphene nanoribbons. Exposing the carbon nanotubes to an alkali metal source in the absence of a solvent, generally while being heated, results in opening of the carbon nanotubes substantially parallel to their longitudinal axis, which may occur in a spiralwise manner in an embodiment. The graphene nanoribbons of the present disclosure are functionalized on at least their edges and are substantially defect free. As a result, the functionalized graphene nanoribbons described herein display a very high electrical conductivity that is comparable to that of mechanically exfoliated graphene.
    Type: Application
    Filed: June 11, 2010
    Publication date: August 2, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: James M. Tour, Dmitry Kosynkin
  • Publication number: 20120189492
    Abstract: In various embodiments, the present disclosure describes fullerene derivatives that are capable of photocatalytically generating reactive oxygen species in the presence of ultraviolet and/or visible light. In some embodiments, the fullerene derivatives are aminofullerenes containing a plurality of amine-terminated moieties covalently bonded to the fullerene cage. The fullerene derivatives may optionally be covalently bonded to a substrate surface for use in photocatalytic disinfection systems for removing various contaminants including, for example, bacteria, viruses, protozoa and chemical pollutants. Methods using the present fullerene and aminofullerene derivatives in various purification processes are also described herein.
    Type: Application
    Filed: June 24, 2010
    Publication date: July 26, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Pedro J.J. Alvarez, Jaesang Lee, Lon J. Wilson, Yuri Mackeyev, Jaehong Kim
  • Patent number: 8223330
    Abstract: A method for producing planar extended electrodes with nanoscale spacings that exhibit very large SERS signals, with each nanoscale gap having one well-defined hot spot. The resulting highly sensitive substrate has extended metal electrodes separated by a nanoscale gap. The electrodes act as optical antennas to enhance dramatically the local electromagnetic field for purposes of spectroscopy or nonlinear optics. SERS response is consistent with a very small number of molecules in the hotspot, showing blinking and wandering of Raman lines. Sensitivity is sufficiently high that SERS from physisorbed atmospheric contaminants may be detected after minutes of exposure to ambient conditions.
    Type: Grant
    Filed: February 12, 2008
    Date of Patent: July 17, 2012
    Assignee: William Marsh Rice University
    Inventors: Douglas Natelson, Daniel Robert Ward, Zachary Kyle Keane
  • Publication number: 20120178181
    Abstract: A device and method for detecting the hybridization of an unmodified target deoxyribonucleic acid (DNA) molecule including exposing a Raman substrate to the unmodified target DNA molecule, where the unmodified target DNA molecule is a complementary DNA molecule to a thiol-terminated probe DNA molecule covalently linked to the Raman substrate. Also, the thiol-terminated probe DNA molecule includes an adenine analog substituted for adenine. The hybridization of the unmodified target DNA molecule to the thiol-terminated probe DNA molecule is detected by measuring a Raman spectroscopic response of the Raman substrate.
    Type: Application
    Filed: August 16, 2010
    Publication date: July 12, 2012
    Applicant: William March Rice University
    Inventors: Aoune Barhoumi, Dongmao Zhang, Nancy J. Halas
  • Patent number: 8217137
    Abstract: The present invention is directed to a series of new compounds, combining the unique properties of fullerenes and bio-active amino acid residues, and to methods for making such compounds. The present invention is directed toward fullerene-based amino acids, and to amino acid residues, peptide chains, proteins, and polypeptides made from such fullerene-based amino acids. The present invention is further directed to amino acid residues, peptide chains, proteins, and polypeptides comprising such fullerene-based amino acids and into which such fullerene-based amino acids have been incorporated. Exemplary compounds have been prepared, and these compounds have been characterized and confirmed with infrared (IR) spectroscopy, nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), etc.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: July 10, 2012
    Assignee: William Marsh Rice University
    Inventors: Andrew R. Barron, Jianzhong Yang
  • Patent number: 8207313
    Abstract: New and useful compounds C. roseus cultured hairy roots are provided, by Isolating flavone glycosides together with a pharmaceutically acceptable carrier. This is accomplished by immersing powdered the hairy roots in methanol to produce an extract, concentrating the extract, resuspending the extract in water, extracting the compound with organic solvent, and isolating the compound from the organic solvent.
    Type: Grant
    Filed: February 18, 2008
    Date of Patent: June 26, 2012
    Assignee: William Marsh Rice University
    Inventors: Ka-Yiu San, Ill-Min Chung, Ateeque Ahmad
  • Publication number: 20120155841
    Abstract: A vessel including a concentrator configured to concentrate electromagnetic (EM) radiation received from an EM radiation source and a complex configured to absorb EM radiation to generate heat. The vessel is configured to receive a cool fluid from the cool fluid source, concentrate the EM radiation using the concentrator, apply the EM radiation to the complex, and transform, using the heat generated by the complex, the cool fluid to the heated fluid. The complex is at least one of consisting of copper nanoparticles, copper oxide nanoparticles, nanoshells, nanorods, carbon moieties, encapsulated nanoshells, encapsulated nanoparticles, and branched nanostructures. Further, the EM radiation is at least one of EM radiation in an ultraviolet region of an electromagnetic spectrum, in a visible region of the electromagnetic spectrum, and in an infrared region of the electromagnetic spectrum.
    Type: Application
    Filed: December 15, 2011
    Publication date: June 21, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Nancy J. Halas, Peter Nordlander, Oara Neumann
  • Publication number: 20120156102
    Abstract: A system including a steam generation system and a chamber. The steam generation system includes a complex and the steam generation system is configured to receive water, concentrate electromagnetic (EM) radiation received from an EM radiation source, apply the EM radiation to the complex, where the complex absorbs the EM radiation to generate heat, and transform, using the heat generated by the complex, the water to steam. The chamber is configured to receive the steam and an object, wherein the object is of medical waste, medical equipment, fabric, and fecal matter.
    Type: Application
    Filed: December 15, 2011
    Publication date: June 21, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Nancy J. Halas, Peter Nordlander, Oara Neumann
  • Publication number: 20120153621
    Abstract: A method for powering a cooling unit. The method including applying electromagnetic (EM) radiation to a complex, where the complex absorbs the EM radiation to generate heat, transforming, using the heat generated by the complex, a fluid to vapor, and sending the vapor from the vessel to a turbine coupled to a generator by a shaft, where the vapor causes the turbine to rotate, which turns the shaft and causes the generator to generate the electric power, wherein the electric powers supplements the power needed to power the cooling unit.
    Type: Application
    Filed: December 15, 2011
    Publication date: June 21, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Nancy J. Halas, Peter Nordlander, Oara Neumann
  • Patent number: 8201517
    Abstract: The present invention involves a method and apparatus for depositing a silicon oxide onto a substrate from solution at low temperatures in a manner that produces homogeneous growth of the silicon oxide. The method generally comprises the following steps: (a) Chemically treating a substrate to activate it for growth of the silicon oxide. (b) Immersing the treated substrate into a bath with a reactive solution. (c) Regenerating the reactive solution to allow for continued growth of the silicon oxide. In another embodiment of the present invention, the apparatus includes a first container holding a reactive solution, a substrate on which the silicon oxide is deposited, a second container holding silica, and a means for adding silica to the reactive solution.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: June 19, 2012
    Assignee: William Marsh Rice University
    Inventors: Andrew R. Barron, Elizabeth Anne Whitsitt
  • Publication number: 20120145997
    Abstract: A hot filament chemical vapor deposition method has been developed to grow at least one vertical single-walled carbon nanotube (SWNT). In general, various embodiments of the present invention disclose novel processes for growing and/or producing enhanced nanotube carpets with decreased diameters as compared to the prior art.
    Type: Application
    Filed: February 6, 2007
    Publication date: June 14, 2012
    Applicant: William Marsh Rice University
    Inventors: Robert H. Hauge, Ya-Qiong Xu
  • Patent number: 8199244
    Abstract: A new digital image/video camera that directly acquires random projections of the incident light field without first collecting the pixels/voxels. In one preferred embodiment, the camera employs a digital micromirror array to perform optical calculations of linear projections of an image onto pseudorandom binary patterns. Its hallmarks include the ability to obtain an image with only a single detection element while measuring the image/video fewer times than the number of pixels or voxels—this can significantly reduce the computation required for image/video acquisition/encoding. Since the system features a single photon detector, it can also be adapted to image at wavelengths that are currently impossible with conventional CCD and CMOS imagers.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: June 12, 2012
    Assignee: William Marsh Rice University
    Inventors: Richard G. Baraniuk, Dror Z. Baron, Marco F. Duarte, Kevin F. Kelly, Courtney C. Lane, Jason N. Laska, Dharmpal Takhar, Michael B. Wakin
  • Patent number: 8187703
    Abstract: The present invention is directed to methods of integrating carbon nanotubes into epoxy polymer composites via chemical functionalization of carbon nanotubes, and to the carbon nanotube-epoxy polymer composites produced by such methods. Integration is enhanced through improved dispersion and/or covalent bonding with the epoxy matrix during the curing process. In general, such methods involve the attachment of chemical moieties (i.e., functional groups) to the sidewall and/or end-cap of carbon nanotubes such that the chemical moieties react with either the epoxy precursor(s) or the curing agent(s) (or both) during the curing process. Additionally, in some embodiments, these or additional chemical moieties can function to facilitate dispersion of the carbon nanotubes by decreasing the van der Waals attractive forces between the nanotubes.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: May 29, 2012
    Assignee: William Marsh Rice University
    Inventors: Jiang Zhu, Valery N. Khabashesku, Haiqing Peng, Enrique V. Barrera, John L. Margrave, Mary Lou Margrave, legal representative
  • Patent number: 8187608
    Abstract: The present invention relates to the ability of SAP to suppress fibrocytes. It also relates to the ability of IL-12, laminin-1, cross-linked IgG and IgG aggregates to suppress fibrocytes. Methods and compositions for suppressing fibrocytes using these proteins are provided. These methods are useful in a variety of applications including treatment and prevention of fibrosing diseases such as scleroderma, pulmonary fibrosis and asthma. Finally, the invention includes assays for detecting the ability of various agents to modulate differentiation into fibrocytes. Such assays may also be used to diagnose scleroderma, pulmonary fibrosis, or other fibrosing diseases.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: May 29, 2012
    Assignee: William Marsh Rice University
    Inventors: Richard Gomer, Darrell Pilling
  • Patent number: 8187599
    Abstract: The present invention relates to the ability of anti-Fc?R antibodies to suppress fibrocytes. Methods and compositions for suppressing fibrocytes are provided. These methods are useful in a variety of applications including treatment and prevention of conditions resulting from fibrosis in the liver, kidney, lung, heart and pericardium, eye, skin, mouth, pancreas, gastrointestinal tract, brain, breast, bone marrow, bone, genitourinary system, a tumor, or a wound.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: May 29, 2012
    Assignee: William Marsh Rice University
    Inventors: Richard Gomer, Darrell Pilling
  • Publication number: 20120129736
    Abstract: A highly oxidized form of graphene oxide and methods for production thereof are described in various embodiments of the present disclosure. In general, the methods include mixing a graphite source with a solution containing at least one oxidant and at least one protecting agent and then oxidizing the graphite source with the at least one oxidant in the presence of the at least one protecting agent to form the graphene oxide. Graphene oxide synthesized by the presently described methods is of a high structural quality that is more oxidized and maintains a higher proportion of aromatic rings and aromatic domains than does graphene oxide prepared in the absence of at least one protecting agent. Methods for reduction of graphene oxide into chemically converted graphene are also disclosed herein. The chemically converted graphene of the present disclosure is significantly more electrically conductive than is chemically converted graphene prepared from other sources of graphene oxide.
    Type: Application
    Filed: May 14, 2010
    Publication date: May 24, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: James M. Tour, Dmitriy V. Kosynkin