Abstract: A dosing unit for use in an ambulatory infusion system, the dosing unit including: a dosing cylinder and a piston arranged inside the dosing cylinder and in a sliding displaceable manner along a displacement axis. The piston is convertible from a storing configuration into an operational configuration, wherein a circumferential sealing member of the piston is mechanically relieved in the storing configuration and is in sealing and sliding engagement with a circumferential inner surface of the dosing cylinder in the operational configuration. The dosing unit includes a configuration switch member in operative mechanical coupling with the piston, the configuration switch member being movable relative to the piston from a storing position into an operational position, thereby switching the piston configuration from the storing configuration to the operational configuration.

Abstract: The invention concerns a method and an apparatus for determining the concentration of an analyte in a body fluid, where the following measures are proposed: providing a layered test element (12) including an enzyme-based chemistry layer which is responsive to the analyte by a color change, applying a sample of the body fluid onto the test element (12), detecting by means of a photometric reflectance measuring device (16) a reflectance value of the test element (12), correcting the measured reflectance value by a predetermined offset value attributed to the test element (12), determining a concentration value of the analyte using the offset-corrected reflectance value.

Abstract: Methods, devices and systems for detecting an analyte in a body fluid are described. A sample of body fluid is applied to a test element having a test field including a test material adapted to change a measurable property in the presence of the analyte. The test element includes a capillary to guide the sample across said test field. The measurable property is measured in a first measurement location providing a first measurement value, and in a second measurement location providing a second measurement value. The analyte is detected by using an evaluation algorithm having at least a first input variable including a difference between the first measurement value and the second measurement value, and at least a second input variable including information relating to an analyte-induced change of the measurable property of the test material in at least part of the test field.

Abstract: A resealable container including a housing, a lid coupled to the housing, and a basket received within the housing and including side walls defining an interior space, and a retainer extending over at least a portion of the interior space and configured to support at least one test element in at least one of a side-to-side direction and a front-to-back direction within the basket.

Abstract: An analyte test meter that detects contact between a user and an electrochemical test strip includes a test strip port, a capacitive sensor positioned proximate to the test strip port, and a controller connected to the test strip port and the capacitive sensor. The controller is configured to identify insertion of the electrochemical test strip into the test strip port, apply a drive signal to the capacitive sensor, measure a first response to the drive signal from the capacitive sensor, identify dosing of a fluid sample on the electrochemical test strip, apply the drive signal to the capacitive sensor after the dosing, measure a second response to the drive signal from the capacitive sensor, and detect contact between a body of a user and at least one electrode in the electrochemical test strip in response to a difference between the first and second responses exceeding a predetermined threshold.

Abstract: This disclosure concerns a method for removing gas and/or gas bubbles from a liquid medicament stored in a reservoir for an infusion pump device. The reservoir comprises a displacing member which is at least partly displaceable relative to the reservoir thereby enabling receiving mechanical oscillations in order to generate mechanical waves in the liquid medicament. The method comprises: providing the reservoir; and transmitting a mechanical oscillation to the displacing member of the reservoir thereby generating a mechanical wave in the liquid medicament for removing gas and/or gas bubbles from the liquid medicament.

Abstract: A portable liquid drug delivery device has a reservoir part and a driving part, and the driving part has a drive that produces a torque. The reservoir part has a reservoir that retains liquid drug and an outlet port is in fluid communication with the reservoir. An engagement member has an inner thread that engages the thread of a piston rod in an engaged position and is disengaged from the thread of the piston rod in a disengaged position. The engagement member is prestressed in the disengaged position to thereby bias the engagement member toward the engaged position. The engagement member only converts the torque of the drive into a linear movement of the piston rod when the engagement member is in the engaged position. The piston is configured, upon the linear movement of the piston rod, to deliver the liquid drug to the outlet port.

Abstract: Systems and methods are provided for improving nutritional element content estimates from one or more individuals and/or determining a therapy or treatment based on a nutritional element content estimate and improving diabetes management. The systems and methods include a therapy or treatment display based on at least one nutritional element content estimate and at least one proficiency index respectively assigned to an individual to improve accuracy and reliability when estimating nutritional element content in foods and/or therapy or treatment based therefrom.

Abstract: A control unit for an electronically controlled pump unit controls the pump unit to infuse insulin into a diabetic's body in a substantially continuous way according to a preset infusion schedule as a function of time. The control unit includes an intervention unit that continuously evaluates a blood-glucose indicative input for detecting an actual or expected hypoglycaemia and executes, in response to an actual or expected hypoglycaemia, a temporary hypoglycaemia intervention. The intervention includes, for an intervention time interval, overriding the preset infusion schedule by temporarily suspending insulin infusion or temporarily reducing insulin infusion below the preset infusion schedule. The intervention unit adapts its way of operation with respect to executing the hypoglycaemia intervention in accordance with a control signal that is separate from the blood-glucose indicative input. The control unit automatically generates the control signal as a function of time and/or based on sensor input.

Abstract: An inventive medical device includes an implantable device, such as an electrochemical sensor. The implantable device has an implantable portion configured for insertion into a patient, a contact portion configured for connection to another device, and an interconnecting portion connecting the implantable portion and the contact portion. A housing is provided that has a first part that is removably connectable with a second part to form a sterile packaging to seal the implantable portion against a surrounding environment. The first part comprises a first sealing surface and the second part comprises a second sealing surface and the first and second sealing surfaces interact to form a sealing area. The interconnecting portion of the implantable device extends through the sealing area. An inventive method of producing the medical device is also disclosed.

Abstract: The present disclosure refers to a method of dynamically saving metadata in a process of operating a medical system, comprising: running a software application for operating a medical device; storing metadata in a transient memory by a controller, wherein the metadata are assigned to one or more operation events while the software application is running; detecting an error operation event by the controller; in response to the detecting the error operation event, transmitting present metadata currently stored in the transient memory and assigned to one or more operation events before the error operation event was detected from the transient memory to a log data memory; storing the present metadata in the log data memory; and storing metadata different from the present metadata and assigned to the error operation event in the log data memory. Further, a medical system, and a computer program product are provided.

Abstract: The present invention relates to a method for guiding a user in interaction with an insulin pump comprising providing in response to a user interaction at least one of (i) a first acoustic signal comprising at least five descending halftones, wherein the duration of each tone is independently selected from a range of from 0.025 s to 5 s; (ii) a second acoustic signal comprising at least five ascending halftones, wherein the duration of each tone is independently selected from a range of from 0.025 s to 5 s; (iii) a third acoustic signal comprising at least seven ascending halftones, wherein the duration of each tone is independently selected from a range of from 0.025 s to 5 s; (iv) a fourth acoustic signal comprising at least two alternating tritones, wherein the duration of each tone is independently selected from a range of from 0.025 s to 5 s; (v) a fifth acoustic signal of four tones with a duration of from 0.025 s to 0.

Abstract: Disclosed is a method for manufacturing a cannula unit with a cannula housing and a cannula, in which a cannula is injection molded onto a molding core pin having an outer diameter d1 to produce a cannula having a distal end with a larger outer diameter than the outer diameter of the remaining cannula, a first distal section adjoining the distal end, a second proximal section adjoining the first distal section, and a proximal end. A cannula housing is injection molded onto the distal end and the first distal section of the cannula and the molding core pin is removed from the cannula. A piercing needle with an outer diameter d4 is threaded into the cannula, wherein the diameter d4 of the piercing needle is chosen such that it is smaller than the diameter d1 of the molding core pin.

Abstract: A valve clutch that has a central member extending along a central axis and includes a drive coupler that receives a driving torque. A coupling member is provided that includes coupling pins extending parallel to the central axis. A valve is rotatably disposed around the central axis between inlet and outlet positions. A sleeve is configured to rotationally engage the valve, the sleeve including at least one clamping member. The valve clutch is reversibly changeable between (1) an unengaged configuration wherein a driving torque received by the central member is not transmitted to the sleeve member, and (2) an engaged configuration wherein the at least one coupling pin is clamped between the central member and the at least one clamping member, thereby transmitting the driving torque that is received by the central member via the sleeve member to the valve member.

Abstract: Embodiments related to a system and method managing the implementation, execution, data collection, and data analysis of a structured collection procedure running on a portable, hand-held collection device are disclosed. The collection device performing the structured collection procedure has program instructions that when executed by a processor causes the processor to initiate automatically a schedule of events of the structured collection procedure upon one or more entry criterions being met at some unknown time, store in memory patient data collected in accordance to the schedule of events, end automatically the structured collection procedure upon one or more exit criterions being met at some unknown time, and mark/indicate the structured collection procedure as completed if no exception occurred during performance of an event in the schedule of events.

Abstract: Methods for detecting an analyte in a body fluid are described as well as devices and systems adapted for performing such methods. In embodiments of the method, a sample of body fluid is applied to a test element having at least one test field including at least one test material that is adapted to change at least one measurable property in the presence of the analyte. The test element further includes a capillary to guide the sample across said test field in a flow direction. The test element also includes first and second measurement locations offset from each other in the flow direction. The measurable property is measured in at least one first measurement location, providing at least one first measurement value, and it is measured in at least one second measurement location, providing at least one second measurement value.

Abstract: An adapter for use with an appliance for administering an injectable product, the adapter serving to create a product connection between a catheter and a product container that can be inserted into the appliance, and including a thread for screwing the adapter to the appliance, a stop for fixing the container in the longitudinal direction of the thread, an attachment piece to which the catheter may be connected, and a product channel that extends through the attachment piece and the thread.

Abstract: A method is provided for evaluating a set of measurement data from an oral glucose tolerance test. The method may include calculating a similarity measure that quantifies the similarity between a time profile of the series of measured data of the glucose concentration and a corresponding glucose reference profile. The method may include calculating a further similarity measure that quantifies the similarity between the profile of the series of measured values of the further analyte concentration and the corresponding analyte sample profile, wherein the data set is represented by a point in a vector space that comprises coordinate axes that are formed by the similarity measures, whereby the coordinates of said point contain the calculated values of the similarity measures.

Abstract: A BLUETOOTH® enabled computing device is configured to use a “pseudo” device identifier to prevent undesired device interference during BLUETOOTH® pairing.

Abstract: A system and method for analyzing measured blood glucose values is disclosed, wherein the system includes a display device, a memory device, and a processor having program instructions which when executed cause the processor to provide blood glucose measurement information including a plurality of measured blood glucose values collected within a measurement time frame, perform a pre-analysis of the blood glucose measurement information, provide analysis data representing statistical blood glucose level information for the plurality of measured blood glucose values by performing an analysis of the plurality of measured blood glucose values, and provide output analysis data representing the analysis data, wherein the provision of analysis data and/or the provision of output analysis data are performed if, in the step of performing the pre-analysis, at least one of the following control checks is positive a fidelity check, and an adherence check.