Abstract: A lancet magazine for use in a lancing aid is described comprising a plurality of lancets each having a lancet body at the proximal end of the lancet and a lancet tip at the distal end of the lancet, where the proximal end of the lancet points in the direction of the proximal end of the housing of the lancet magazine and the distal end of the lancet is aligned in the direction of the distal end of the housing and the lancets in the unused state are completely surrounded by the housing. Furthermore, an extension unit is movably connected to the housing in such a manner that the housing can be extended by movement of the extension unit in the direction of the distal end of the housing such that the lancet is prevented from emerging from the lancet magazine.

Abstract: A method and system for determining a failsafe value for a biosensor having two perimeter electrodes, a distal electrode, and a proximal electrode are disclosed. A liquid measuring medium is applied to a capillary channel of the biosensor. The method includes applying an alternating voltage to the perimeter electrode and the proximal electrode, measuring conductivity to determine a first impedance between the perimeter electrode and the proximal electrode, applying the alternating voltage to the perimeter electrode and the distal electrode, measuring conductivity to determine a second impedance between the perimeter electrode and the distal electrode, determining a value using the first impedance and the second impedance, and providing an error message to the user if the value is out of tolerance. If the value is out of tolerance, then defects or breaks in the electrodes and/or reagent in a reaction area are present and the method disallows the test result.

Abstract: The present invention relates to improved variants of variants of the Glucose Dehydrogenases (GlucDH) derived from Bacillus subtilis having improved properties in the presence of cNAD as cofactor, to genes encoding such variant GlucDHs, to proteins of such GlucDH variants, and to different applications of these GlucDH variants, particularly for determining concentrations of sugars, especially of glucose, in samples such as bodily fluids, especially blood.

Abstract: An insertion device (110) for inserting an analyte sensor (114) into a body tissue is proposed. The insertion device (110) comprises an insertion needle holder (120) and a drive mechanism (124) for linearly driving the insertion needle holder (120) in a longitudinal direction (126). The drive mechanism (124) comprises at least one actuator (132) for actuating the drive mechanism (124). The actuator (132) comprises at least one actuator arm (136, 138) which is pivotable about at least one axle (140) in order to actuate the drive mechanism (124). The insertion device (110) further comprises at least one protection against reuse including at least one locking mechanism (178). The locking mechanism (178) is adapted to at least partially prevent a back-pivoting of the actuator arm (136, 138) in a direction reversing the actuation direction once the actuator arm (136, 138) has been pivoted by at least one threshold angle.

Abstract: The present disclosure refers to a computer-implemented method for analyzing glucose monitoring data indicative of a glucose level in a bodily fluid, comprising: receiving first glucose monitoring data representing a plurality of first glucose monitoring signals each indicative of a glucose level in a bodily fluid at a measurement time, the first glucose monitoring signals detected in one or more glucose measurement time periods over a first monitoring time period of a continuous glucose monitoring, the first monitoring time period being less than or equal to 24 hours; determining, from the first glucose monitoring data, first range events comprising at least one first range event selected from the following group: a normal glucose level event, a hyperglycaemia event, and a hypoglycaemia event; determining, for the at least one first range event, a number of first range events indicating how often the at least one first range event is determined for the first monitoring time period; providing a first minimum

Abstract: A method for analyzing physiological measurement values of a user is proposed. The method comprises at least one data acquisition step, wherein, during the data acquisition step, physiological measurement values of the user are acquired at different measurement times and stored in a measurement data record; at least one pattern selection step, wherein, during the pattern selection step, measurement values acquired during one comparison time interval are selected as at least one comparison pattern; and at least one pattern recognition step, wherein, during the pattern recognition step, patterns corresponding to the comparison pattern are sought after in the measurement data record.

Abstract: A patient diabetes monitoring system with an efficient unsupervised daily monitoring profile clustering algorithm, a method, and a computer product thereof are disclosed. The system may include a physiological data input device or sensor which receives a plurality of physiological measurements to generate a dataset, a memory which stores a clustering algorithm, and a processor. The clustering algorithm when executed by the processor, causes the processor to automatically pre-process the dataset to control an amount of bias/aggressiveness from the collected unsupervised daily monitoring profiles, thereby generating a pre-processed dataset, build a similarity matrix from the pre-processed dataset, and output an optimum number of similarity clusters found by the processor from the similarity matrix.

Abstract: A handheld diabetes management device for managing blood glucose test data and continuous glucose monitoring data includes a port configured to receive a test strip, a wireless transceiver, a communications processor, and a user interface processor. The communications processor communicates with the wireless transceiver to periodically collect glucose measurement data from a continuous glucose monitoring device and to store the glucose measurement data in a first data storage module. The communications processor is operable to consume electrical power at a first rate. The user interface processor communicates with the communication processor to receive the glucose measurement data and operable to display the glucose measurement data on the device. The communications processor operates asynchronously from operation of the user interface processor to collect the glucose measurement data and the user interface processor operates to consume electrical power at a second rate that is higher than the first rate.

Abstract: A method is described herein to detect and treat hypoglycemia. An example of this method involves the detection of hypoglycemia in a patient with a computing device, computation of a recommended carbohydrate amount to ingest by the patient with the computing device in response to said detecting the hypoglycemia, output of the recommended carbohydrate amount with the computing device, and the performance of a hypoglycemia surveillance with the computing device to determine whether the recommended carbohydrate amount remedied the hypoglycemia.

Abstract: A medical system, an analyte measurement device, a medication device and a method for transcutaneously inserting an insertable element into a body tissue are disclosed. The medical system comprises: at least one electronics unit having at least one electronics component; at least one adhesive surface for attachment of the electronics unit to a skin site of a host; at least one first subsystem configured for being at least partially inserted into the host; at least one second subsystem, wherein the second subsystem comprises at least one secondary sensor, wherein the first subsystem and the second subsystem are operably connectable to the electronics unit, wherein the second subsystem is physically attachable to the medical system.

Abstract: A production method for producing a transport and transfer receptacle for at least one fluid medium, for example, for at least one sterile liquid is proposed. The method comprises supplying at least one container for receiving the fluid medium. At least one energy unit is supplied. The energy unit effects—for example, complete—emptying of the fluid medium from the container when the transport and transfer receptacle is used. The fluid medium is introduced into the container and the container is closed. The fluid medium is charged with positive pressure, for example, using the energy unit. The positive pressure is maintained until the fluid medium is removed. Furthermore, a transport and transfer receptacle which can be produced according to the production method and which has at least one packaging is proposed.

Abstract: A structured testing method for diagnostic or therapy support of a patient with a chronic disease and devices thereof are disclosed which implement a structured collection procedure based on a medical use case and/or question which provides at least one or more parameters defining entry criterion, a schedule of events, adherence criterion, and exit criterion. The entry criterion establish conditions needed to be met prior to obtaining biomarker data from the patient. Each event can include one or more of a performance time, patient guidance to perform the event, a request for information from the patient a request for patient action, and a request for collection of biomarker data from the patient. The adherence criterion can be used to assess whether an event performed is acceptable to addressing the medical use case and/or question, and the exit criterion establishes conditions needed to be met prior to exiting the collection procedure.

Abstract: Micro-fluidic chambers for use in a liquid medicament delivery system, include a bottom substrate and a top cover, the top cover being spaced from the bottom substrate so as to define a height of the chamber, wherein, one or more walls or fillings are positioned in the chamber, the walls or fillings defining a fluid channel there between such that the fluid channel extends from an inlet conduit to an inlet of the chamber to an outlet conduit connected to an outlet of the chamber, wherein, each of the walls or fillings has a height less than the height of the chamber so as to define a fluid gap between a top surface of each wall or filling and the top cover; and wherein, the dimensions of the walls or fillings and the chamber are such that the fluid gap will be filled with liquid by capillary forces via the fluid channel when liquid is introduced into the fluid chamber.

Abstract: The invention relates to a carrier system for an object worn on the body, comprising a flexible carrier plaster, which has a flat carrier layer and an adhesive layer, applied to the lower face of said carrier layer, which adhesive layer adheres to the skin of a body part when pressed thereon, the adhesive layer consisting of a pressure-sensitive adhesive, and further comprising, on the upper face of the carrier layer facing away from the skin, a rigid mounting platform. According to this disclosure, a joining region of the mounting platform is permanently joined to the upper face of the carrier layer via a structural adhesive connection that consists of a structural adhesive.

Abstract: A device for positioning a probe in living tissue, the device including a casing having an underside for positioning on the tissue, the probe, which can be moved relative to the casing beyond the underside in an insertion direction to be inserted into the tissue, and a signal means carried by the casing such that it can be moved in the insertion direction to an end position, wherein the signal means slaves the probe when moving in the insertion direction.

Abstract: An insertion device including an insertion needle holder and a drive mechanism for linearly moving the insertion needle holder in a puncturing direction. The insertion needle holder also includes at least one actuating element for actuating a drive mechanism. The drive mechanism converts a driving motion of the actuating element, which extends transversely or opposite to the puncturing direction, into a puncturing motion of the insertion needle holder.

Abstract: Embodiments related to a self-administered, behavior modification program facilitated through a structured tailoring method and system thereof which accelerates and enhances the internalization process of the individual, and which provides help when the individual begins to fail in adhering or continuing with the behavior modification are disclosed. Program instructions that when executed by a processor causes a processor to initiate automatically a schedule of events of a structured tailoring procedure upon entry criteria being met at some unknown time, provide intervention according to the intervention preferences when the adherence criteria for one of the events has not been met, and end automatically the structured collection procedure upon exit criteria being met at some unknown time.

Abstract: The test elements are provided that are adapted to detect at least one analyte in a sample. At least some of the test elements are provided with a defect marking which contains information about defectiveness of the test elements. The test elements include at least one radiation-sensitive material. The test elements are exposed to at least one radiation, the radiation being adapted to induce marking in the form of at least one optically detectable change in the radiation-sensitive material.

Abstract: The present disclosure refers to an implant needle (1) for introducing an implant into a body of a patient, comprising a receiving portion configured to receive an implant and provided in a hollow needle main body (2), and a taper-shaped tip portion (3). The taper-shaped tip portion (3) is further comprising: a first slant surface (14a) contiguous to a first outer peripheral surface (15) of the hollow needle main body (2), wherein the first slant surface (14a) is provided as a first non-cutting edge; a second slant surface (16a) contiguous to a second outer peripheral surface (17) of the hollow needle main body (2), wherein the second slant surface (16a) is provided as a second non-cutting edge; and a pair of sharpened surfaces (9a, 9b) symmetric with respect to an edge point (10) and a longitudinal axis (13) of the needle main body (2), wherein the sharpened surfaces (9a, 9b) are both provided with a cutting edge.

Abstract: A system and method is provided for analyzing a glucose state. A method may include identifying a target glucose state and an initial glucose state. The method may include calculating a target return path for a transition from the initial glucose state to the target glucose state. The target return path may comprise at least one intermediate glucose state associated with the transition from the initial glucose state to the target glucose state. The target return path may be calculated based on a hazard associated with the at least one intermediate glucose state of the target return path.