Patents Assigned to Rutgers, The State University of New Jersey
  • Patent number: 10295543
    Abstract: Therapeutic compositions for treating diseased cells such as cancer cells in a patient, formulated from a plurality of therapeutic agents selected from radiopharmaceuticals, chemotherapeutic agents and radionuclide labeled antibodies. Methods for predicting the response of an individual patient's cells to therapeutic intervention are also disclosed.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: May 21, 2019
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Roger W. Howell, John M. Akudugu, Jordan B. Pasternack, Venkata S. Neti
  • Publication number: 20190144608
    Abstract: The invention provides a polymer comprising two or more residues of formula III or IV or salts thereof: wherein dash line, X, Y, Q, L, M, n, R1, R2, Ra, Rb, Rc and Rd have any of the values defined in the specification, as well as synthetic intermediates and synthetic methods useful for preparing the compounds. The polymer is useful to treat contaminated water by chelating metal.
    Type: Application
    Filed: April 24, 2017
    Publication date: May 16, 2019
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Agostino Pietrangelo, Anshuman Mangalum
  • Patent number: 10286088
    Abstract: Disclosed is a method of non-invasive infrared imaging, comprising (a) administering a composition containing infrared-emitting particles which contain rare earth elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles; and (b) irradiating with infrared radiation, where both excitation and emission spectra of the encapsulated particles are in the infrared region. Analogous methods of image-guided biomedical intervention, and drug tracking and delivery are also disclosed. Also disclosed is a composition for biomedical applications, containing infrared-emitting particles which contain rare earth-elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: May 14, 2019
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Dominik J. Naczynski, Mei-Chee Tan, Richard E. Riman, Charles Roth, Prabhas V. Moghe
  • Publication number: 20190127361
    Abstract: Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.
    Type: Application
    Filed: June 16, 2017
    Publication date: May 2, 2019
    Applicants: Rutgers, The State University of New Jersey, The Curators of the University of Missouri
    Inventors: William J. Welsh, Raymond Birge, Vladyslav Kholodovych, Youyi Peng, Thomas Walter Comollo, Stanley G. Kimani, Kamlendra Singh
  • Publication number: 20190119199
    Abstract: The invention provides an antibacterial compound of formula I: or a salt thereof, as well as an antibacterial compound of formula II: or a salt thereof, wherein R1, R2, X, Y and n have any of the values defined in the specification.
    Type: Application
    Filed: October 18, 2018
    Publication date: April 25, 2019
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Kathryn E. Uhrich, Allison Faig
  • Patent number: 10266448
    Abstract: A bonding element, a bonding element matrix and composite materials with a wide range of attractive properties that may be optimized, including, but not limited to, mechanical properties, thermal properties, magnetic properties, optical properties and nuclear properties, as a result of a first layer and second layer structure or core, first layer, and second layer structure of the bonding elements, as well as methods for making the bonding elements and the corresponding ceramic and/or composite materials.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: April 23, 2019
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Richard E. Riman, Surojit Gupta, Vahit Atakan, Qinghua Li
  • Patent number: 10266647
    Abstract: Disclosed are monomeric compounds which may be polymerized to form novel biodegradable and bioresorbable polymers and co-polymers. These polymers and co-polymers, while not limited thereto, may be adapted for radiopacity and are useful for medical device applications and controlled release therapeutic formulations.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: April 23, 2019
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Durgadas Bolikal, Joachim B. Kohn
  • Patent number: 10258027
    Abstract: The described invention provides a gel formulation of a composition comprising at least one insecticide in an amount effective to control an insect larval population, an apparatus for autodissmenination of an insecticide for insect management containing (1) a reservoir (2) a transfer plate and cover, and (3) a mesh component, a method and a system for autodissemination for effectively controlling an insect larval population. Also disclosed is an improvided biphasic autodissemination station for control of undesirable insect populations.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: April 16, 2019
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Randy Gaugler, Devi Suman, Yi Wang
  • Patent number: 10253154
    Abstract: A method for forming a graphene-reinforced-polymer matrix composite by distributing graphite microparticles into a molten thermoplastic polymer phase comprising one or more molten thermoplastic polymers; and applying a succession of shear strain events to the molten polymer phase so that the molten polymer phase exfoliates the graphene successively with each event, until tearing of exfoliated multilayer graphene sheets occurs arid produces reactive edges on the multilayer sheets that react with and cross-link the one or more thermoplastic polymers; where the one or more thermoplastic polymers are selected from thermoplastic polymers subject to UV degradation.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: April 9, 2019
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Thomas Nosker, Jennifer Lynch, Bernard Kear, Justin Hendrix, Gordon Chiu
  • Publication number: 20190100803
    Abstract: The present invention is a method, comprising: obtaining a sample of an esophageal tissue from a subject, wherein the sample of the esophageal tissue comprises or is suspected of comprising a break of chromosome 2 (chr2), a break of chromosome 10 (chr10), a break of chromosome 16 (chr16), or any combination thereof, and detecting in the sample of esophageal tissue whether the break of chr2 is present, whether the break of chr10 is present, whether the break of chr16 is present, or any combination thereof, by contacting the sample of esophageal tissue with a first detectably labeled probe, a second detectably labeled probe, a third detectably labeled probe, or any combination thereof, and detecting binding between: the first detectably labeled probe and the break of chr2, the second detectably labeled probe and the break of chr10, the third detectably labeled probe and the break of chr16, or any combination thereof.
    Type: Application
    Filed: March 8, 2017
    Publication date: April 4, 2019
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Kiron Das, Manisha Bajpai, Hana Aviv
  • Publication number: 20190093640
    Abstract: An actuator comprising a flexible substrate having a surface comprising one or more active regions, each of the active regions having disposed thereon an electrochemically active film comprising a plurality of 1T phase 2D MoS2 nanosheets which impart a first force upon the flexible substrate in response to electrochemical charging of ions in the 2D MoS2 nanosheets and impart a second force upon the flexible substrate in response to electrochemical discharging of ions in the 2D MoS2 nanosheets, wherein the first and second forces imparted to the flexible substrate each being sufficient to displace the flexible substrate. The flexible substrate may comprise a polymer substrate and the electrochemically active film may comprise a conductive layer having disposed thereon the plurality of 1T phase 2D MoS2 nanosheets.
    Type: Application
    Filed: August 29, 2018
    Publication date: March 28, 2019
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Manish Chhowalla, Muharrem Acerce, E. Koray Akdogan
  • Patent number: 10244356
    Abstract: A method of tracking a service queue using a single-point signal monitor in which at least one customer carries a wireless device may include: receiving a received signal strength from the wireless device as a trace; identify first segments of the trace containing mostly positive sloped received signal strength; identify second segments of the trace containing mostly negative sloped received signal; extract attributes from the first and second segments as child variables for two parent nodes in a Bayesian Network in which the two parent nodes respectively model a beginning of service and a leaving period for a service queue; and inputting the extracted attributes into Bayesian Network; and determining a beginning of service and leaving period using the Bayesian Network. The method may also include determining critical time points in a trace using a K-L divergence technique.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: March 26, 2019
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, STEVENS INSTITUTE OF TECHNOLOGY
    Inventors: Yan Wang, Jie Yang, Yingying Chen, Richard P. Martin, Marco Gruteser
  • Patent number: 10241116
    Abstract: The invention relates to novel luminescent compositions of matter containing two fluorophores (sensitizers), synthetic methods for making the compositions, macromolecular conjugates of the compositions, and the use of the compositions and their conjugates in various methods of detection. The invention also provides kits containing the compositions and their conjugates for use in the methods of detection.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: March 26, 2019
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Arkady Mustaev, Salvatore A. E. Marras
  • Publication number: 20190084919
    Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
    Type: Application
    Filed: February 23, 2017
    Publication date: March 21, 2019
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit Parhi, Malvika Kaul, Daniel S. Pilch
  • Publication number: 20190088152
    Abstract: A rehabilitation system is disclosed herein. In some embodiments, the rehabilitation system comprises a first computer terminal accessible by a first user, the first computer terminal having a memory for storing instructions including a game for rehabilitation of at least one of the first user's shoulder, elbow, wrist, or fingers; a sensor for detecting motion of the first user's hand as the first user is playing the game; a second computer terminal that displays the game in real-time on the second computer terminal as the first user is playing the game on the first computer terminal, and wherein a difficulty level of the game can be remotely adjusted from the second computer terminal; and a server that acquires rehabilitation data from the first computer terminal as the first user plays the game, and wherein the server permits access, on the second computer terminal, to the rehabilitation data collected.
    Type: Application
    Filed: September 19, 2018
    Publication date: March 21, 2019
    Applicants: New Jersey Institute of Technology, Rutgers, The State University of New Jersey
    Inventors: Sergei Adamovich, Amanda Cronce, Qinyin Qiu, Jigna Patel, Gerard Fluet, Alma Merians
  • Patent number: 10226506
    Abstract: This invention concerns compositions and methods of treating or diagnosing inflammatory disorders and other disorders, as well as compositions and methods of treating HIV.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: March 12, 2019
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, ACTINOBAC BIOMED, INC.
    Inventors: Scott C. Kachlany, Benjamin Belinka
  • Patent number: 10227315
    Abstract: The present disclosure relates to benzamide compounds, prodrugs of the compounds, pharmaceutical compositions containing the compounds and/or the prodrugs and methods of using the compounds, prodrugs and pharmaceutical compositions in the treatment of diseases related to lipid metabolism including diabetes, Non-Alcholic Fatty Liver Disease (NAFLD), Non-Alcholic Steathohepatitis (NASH), diseases caused by abnormal cell proliferation including cancer, psoriasis, and infectious diseases.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: March 12, 2019
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Shengkan Jin, David J. Augeri, Bin Cao, Hanlin Tao
  • Patent number: 10221133
    Abstract: The invention provides organic complexes of Zn2+ of formula (I) that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: March 5, 2019
    Assignees: Rutgers, The State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • Publication number: 20190060210
    Abstract: Described herein are oral care compositions comprising amphiphilic macromolecules, along with methods of making and using same.
    Type: Application
    Filed: August 22, 2018
    Publication date: February 28, 2019
    Applicants: Colgate-Palmolive Company, Rutgers, the State University of New Jersey
    Inventors: Carl MYERS, Guillaume PICQUET, Kathryn E. UHRICH, Jennifer CHAN WOO, Jeannette Elizabeth MARINE
  • Patent number: 10217457
    Abstract: In one embodiment, a semantic classifier input and a corresponding label attributed to the semantic classifier input may be obtained. A determination may be made whether the corresponding label is correct based on logged interaction data. An entry of an adaptation corpus may be generated based on a result of the determination. Operation of the semantic classifier may be adapted based on the adaptation corpus.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: February 26, 2019
    Assignees: AT&T INTELLECTUAL PROPERTY II, L.P., RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Mazin Gilbert, Esther Levin, Michael Lederman Littman, Robert E. Schapire