Patents Assigned to Rutgers, The State University of New Jersey
  • Publication number: 20220378840
    Abstract: Compositions, containers and kits for low temperature storage of a specified quantity of packed red blood cells (RBCs) include L-camitine, HES and blood plasma proteins. Methods of storing a packed RBC blood product, transfusing a packed RBC blood product into a subject, and treating anemia, ischemia, hypoxia, a hemoglobin disorder, or a hematopoietic disorder in a subject (e.g., a human) include the compositions, containers, kits and blood products.
    Type: Application
    Filed: November 25, 2020
    Publication date: December 1, 2022
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Wise Young, Dongming Sun, Iman Tadmori
  • Patent number: 11512208
    Abstract: A flame or heat flux protective coating composition, which includes a dispersion of fiberglass, hollow glass spheres, or a combination of both in silicone. A flame or heat flux protective sheet, which includes hollow glass spheres dispersed in silicone in a sheet form or fiberglass and silicone in a sheet form, wherein the fiberglass is dispersed in the silicone or the fiberglass is a woven cloth coated with the silicone is also presented. Articles incorporating the flame or heat flux protective coating or sheet form and methods for coating an article with the flame or heat flux protective coating composition are also presented.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: November 29, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Thomas J. Nosker, Jennifer K. Lynch-Branzoi, Mark Mazar, Patrick L. Nosker
  • Publication number: 20220369951
    Abstract: A probe generates location signals, and has an electrode at a distal end that acquires from heart chamber surface positions electrical signals due to a conduction wave traversing the surface. A processor derives LATs from the electrical signals, calculates a first time difference between LATs at a first pair of positions and a second time difference between LATs at a second pair of positions. The processor calculates first and second LAT-derived distances as products of the first and second time differences with a conduction wave velocity, identifies an arrhythmia origin at a surface location where a first difference in distances from the location to the first pair of the positions is equal to the first LAT-derived distance, and a second difference in distances from the location to the second pair of the positions is equal to the second LAT-derived distance, and marks the origin on a surface representation.
    Type: Application
    Filed: August 8, 2022
    Publication date: November 24, 2022
    Applicants: Biosense Webster (Israel) Ltd., Rutgers, The State University of New Jersey
    Inventors: Gal Hayam, Michael Timofeyev, Tal Haim Bar-On, Amardeep Saluja
  • Publication number: 20220370687
    Abstract: A three dimensional scaffold for generating cell or protein assemblies. This degradable scaffold can be applied to various types of cells. Also disclosed are methods of treating a condition by implanting the protein or cell assembly prepared according to the method described herein.
    Type: Application
    Filed: May 24, 2022
    Publication date: November 24, 2022
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Ki-Bum Lee, Letao Yang
  • Patent number: 11506592
    Abstract: This disclosure provides an impedance cytometer which includes a carrier that can be attached to a living being, with a biosensor mounted thereto. The bio sensor includes a microfluidic flow channel, formed in the carrier, and an impedance circuit. The microfluidic flow channel accommodates passage of a particle therethrough. The impedance circuit, connected to the microfluidic flow channel, includes a signal generator that produces a high-frequency drive signal applied to the flow channel to produce a biosensor output signal having high-frequency variation resulting from the drive signal and low-frequency variation resulting from impedance variation within the flow channel during the particle's passage. A lock-in amplifier is disposed to (i) amplify the bio sensor output signal, (ii) mix the amplified signal with the drive signal, and (iii) frequency-filter the mixed, amplified signal to output an impedance signal representing the low-frequency impedance variation resulting from the passage of the particle.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: November 22, 2022
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Mehdi Javanmard, Abbas Furniturewalla
  • Publication number: 20220364118
    Abstract: Compositions, non-viral vectors, recombinant viruses, and recombinant viral vectors for inhibiting ?FosB expression or activity in a cell and for treating dyskinesia in a subject (e.g., a human patient having Parkinson's disease and Levodopa-induced dyskinesia) include a nucleic acid sequence encoding a shRNA specific for ?FosB. Methods of using these compositions, non-viral vectors, recombinant viruses, and recombinant viral vectors are also described herein. These compositions, non-viral vectors, recombinant viruses, and recombinant viral vectors and methods of use provide novel therapies for dyskinesia based on the reduction of ?FosB expression and/or activity.
    Type: Application
    Filed: November 2, 2020
    Publication date: November 17, 2022
    Applicants: Rutgers, The State University of New Jersey, Emory University
    Inventors: Mary M. Mouradian, Stella Papa, Jie Zhang, Goichi Beck
  • Publication number: 20220367090
    Abstract: Various embodiments include an electrical device comprising an antiferromagnetic topological insulator having a surface comprising a bulk domain wall configured to support a first type of 1D chiral channel, a surface step configured to support a second 1D chiral channel and intersecting the bulk domain wall to form thereat a quantum point junction.
    Type: Application
    Filed: March 9, 2022
    Publication date: November 17, 2022
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Jedediah Pixley, Nicodemos Varnava, David Vanderbilt, Justin Wilson
  • Publication number: 20220355352
    Abstract: A binder composition for immobilizing a toxic-containing material. This composition has excellent strength developing properties at low temperature and is capable of solidifying soil to suppress the elution of toxic materials from the soil.
    Type: Application
    Filed: October 22, 2020
    Publication date: November 10, 2022
    Applicants: Rutgers, The State University of New Jersey, Taiheiyo Cement Corporation
    Inventors: Takahito Nozaki, Yasuhide Higo, Robert Miskewitz, Ali Maher
  • Patent number: 11479793
    Abstract: The present invention discloses a system for targeted gene editing and related uses.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: October 25, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Shengkan Jin, Juan-Carlos Collantes
  • Patent number: 11479653
    Abstract: A packaging material comprising a graphene-reinforced polymer matrix composite (G-PMC) is disclosed. The packaging material has improved barrier resistance to gas and liquid permeants. Also disclosed is a method of improving barrier resistance of a polymer to a permeant, the method comprising forming a graphene-reinforced polymer matrix composite within the polymer. The packaging material may be used for packaging food, drug, perfume, etc. and to make various containers.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: October 25, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Jennifer K. Lynch-Branzoi, Thomas J. Nosker, Bernard H. Kear, Charles T. Chang
  • Patent number: 11479652
    Abstract: A method for forming a graphene-reinforced polymer matrix composite is disclosed. The method includes distributing graphite microparticles into a molten thermoplastic polymer phase; and applying a succession of shear strain events to the molten polymer phase so that the molten polymer phase exfoliates the graphite successively with each event until at least 50% of the graphite is exfoliated to form a distribution in the molten polymer phase of single- and multi-layer graphene nanoparticles less than 50 nanometers thick along the c-axis direction.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: October 25, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Thomas J. Nosker, Jennifer K. Lynch-Branzoi, Justin W. Hendrix, Bernard H. Kear, Gordon Chiu, Stephen Tse
  • Publication number: 20220333183
    Abstract: This invention relates to methods for analyzing nucleic acids. The disclosure provides methods of a primer-dependent amplification and detection method that is capable of amplifying and detecting in a sample as few as ten copies of at least one rare intended target sequence in the presence of abundant closely related unintended target sequences. Also provided are reaction compositions and kits for performing the methods.
    Type: Application
    Filed: October 1, 2020
    Publication date: October 20, 2022
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Fred R. Kramer, Diana Vargas-Gold
  • Patent number: 11472918
    Abstract: The present invention provides new classes of phenol compounds, including those derived from tyrosol and analogues, useful as monomers for preparation of biocompatible polymers, and biocompatible polymers prepared from these monomeric phenol compounds, including novel biodegradable and/or bioresorbable polymers. These biocompatible polymers or polymer compositions with enhanced bioresorbabilty and processibility are useful in a variety of medical applications, such as in medical devices and controlled-release therapeutic formulations. The invention also provides methods for preparing these monomeric phenol compounds and biocompatible polymers.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: October 18, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Joachim B. Kohn, Durgadas Bolikal, Julian Chesterman, Jarrod Cohen
  • Patent number: 11474127
    Abstract: An apparatus, including: a scanning probe microscope head with a frame configured to fit within an insert of a cryostat, and a scanner, a probe and a sample holder all disposed within the frame; and a coarse motor assembly disposed within the frame and comprising: a positionable component; and coarse motors. The coarse motors are configured to move the positionable component relative to the frame along an X axis, a Y axis, and a Z axis. The apparatus further includes a universal electrical base connection with half of a plug/socket arrangement. The plug/socket arrangement is configured to provide electrical communication between the scanning probe microscope head and a base which has a second half of the plug/socket arrangement when the scanning probe microscope head is lowered onto the base.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: October 18, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Angela Coe, Guohong Li, Eva Y. Andrei
  • Patent number: 11470820
    Abstract: An artificial feeding system for maintenance and growth of hematophagous insects is disclosed to comprise a blood-free diet formulation and a feeding device. The blood-free diet formulation comprises effective amounts of a protein source and a carbohydrate source, wherein the blood-free diet formulation is suitable for egg production and colony maintenance of hematophagous insects. The feeding device comprises a diet reservoir for receiving the blood-free diet formulation and a feeding platform for hematophagous insects to feed the blood-free diet formation from the diet reservoir.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: October 18, 2022
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Randy Gaugler, Devi S. Suman, Kshitij Chandel, Yi Wang
  • Patent number: 11468322
    Abstract: A method of generating a set of examples for explaining decisions made by a machine learning program, involving receiving a set of training data for training the program, and for given subsets of the training data, determining each of (a) a probability of a user correctly inferring a future decision of the program after observing the respective decisions of the program for the given subset of the training data, (b) a suitability of a size of the given subset, and (c) an average probability of the user correctly inferring a future decision of the program after observing the respective decisions of the program for an unspecified subset of the training data. The determinations (a), (b) and (c) are used to score each of the given subsets of training data, and a subset of training data is selected as the generated set of examples based on the scores.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: October 11, 2022
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Patrick Shafto, Scott Cheng-Hsin Yang, Wai Keen Vong, Ravi Sojitra
  • Patent number: 11465996
    Abstract: The present disclosure provides compounds which are useful for a number of catalytic transformations of organic molecules, non-limiting examples including dehydrogenation of alkanes. The present disclosure further relates to methods of preparing the compounds of the present disclosure.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: October 11, 2022
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Alan S. Goldman, Thomas R. Dugan
  • Patent number: 11458121
    Abstract: Disclosed herein are compounds of formula I: or a salt thereof and compositions comprising a compound of formula I or a pharmaceutically acceptable salt thereof. Also disclosed herein are methods for treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I or a pharmaceutically acceptable salt thereof, alone or in combination with a bacterial efflux pump inhibitor.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: October 4, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Edmond J. LaVoie, Ajit Parhi, Hye Yeon Sagong
  • Patent number: 11459603
    Abstract: The present invention relates to the detection of nucleic acids sequences in situ using hybridization probes and generation of amplified hybridization signals, wherein background signal is reduced and sensitivity is increased.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: October 4, 2022
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sanjay Tyagi, Salvatore A. E. Marras
  • Patent number: 11461442
    Abstract: A user input system comprising a vibration motor, a sensor and a processor in communication with the sensor. The vibration motor is in contact with a surface and generates vibrations in the surface. The vibrations can be altered by a user touching the surface to create altered vibrations. The sensor is in contact with the surface and detects the altered vibrations. The processor receives and analyzes data corresponding to the altered vibrations. The processor determines, based on the analyzed data, whether a user's touch on the surface matches a stored vibration profile of the user.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: October 4, 2022
    Assignees: Rutgers, The State University of New Jersey, The UAB Research Foundation
    Inventors: Yingying Chen, Jian Liu, Chen Wang, Nitesh Saxena