Patents Assigned to Saitama University
  • Patent number: 11160877
    Abstract: The present invention relates to a targeting-type capsule for drug delivery systems. The present invention addresses the problem of providing a capsule for drug delivery systems by utilizing the reactivity of a thiol with an alkyl halide, wherein the capsule comprises a silole-containing carbosilane dendrimer and a labeling protein containing a target recognition site (e.g., green fluorescent protein), can include a biological polymer or another molecule therein, and can deliver the biological polymer or the like selectively into a target cell.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: November 2, 2021
    Assignees: Saitama University, QUARRYMEN & Co. Inc.
    Inventors: Miho Suzuki, Ken Hatano, Shojiro Yoshida, Yasuhiro Yamashita
  • Patent number: 10971358
    Abstract: A substrate manufacturing method capable of easily obtaining a thin magnesium oxide single crystal substrate is provided. A first step is performed which disposes a condenser for condensing a laser beam on an irradiated surface of a magnesium oxide single crystal member in a non-contact manner. A second step is performed which forms processing mark lines in parallel by irradiating the laser beam to the surface of the single crystal substrate under designated irradiation conditions to condense the laser beam into an inner portion of the single crystal substrate while moving the condenser and the single crystal substrate relative to each other in a two-dimensional manner.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: April 6, 2021
    Assignees: SHIN-ETSU POLYMER CO., LTD., SHIN-ETSU CHEMICAL CO., LTD., NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Junichi Ikeno, Yohei Yamada, Hideki Suzuki, Hitoshi Noguchi
  • Patent number: 10918726
    Abstract: The object of the present invention is to provide an aggregatable carrier material for drug delivery system and a micelle formed thereof. The present invention provides an aggregatable carrier material for drug delivery system, which is formed by utilizing the reaction between thiol group and alkyl halide. It is formed by using carbosilane dendrimers containing silole and labeled proteins such as green fluorescent protein in aqueous solvent or in mixed solvent of the aqueous solvent and organic solvent. The micelle composed of the material may incorporate compounds having a variety of molecular weight and biopolymers in the aqueous solvent.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: February 16, 2021
    Assignees: QUARRYMEN & Co. Inc., Saitama University
    Inventors: Miho Suzuki, Ken Hatano, Shojiro Yoshida, Yasuhiro Yamashita
  • Patent number: 10923354
    Abstract: An etching method in which: molten sodium hydroxide in a prescribed temperature range is used as a molten alkali, whereby an Si surface of an etching surface of an SiC substrate, in which the substrate surface is configured from the Si surface and a C surface, is removed at a higher speed than is the C surface while an oxide film is formed on the etching surface in a high-temperature environment containing oxygen.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: February 16, 2021
    Assignee: NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Junichi Ikeno, Yohei Yamada, Hideki Suzuki
  • Patent number: 10876588
    Abstract: In the spring mechanism, the negative spring mechanism biasing the loading plate to the positive side in the z-direction has the spring shaft and interspring. The spring shaft is rotatably connected to the fixed part and is connected through the slider with respect to the loading plate so that it can rotate and can move in the x-direction. The connection part with the loading plate is positioned on the positive side in the z-direction and on the positive side in the x-direction relative to the connection part with the fixed part. An elastic force countering the compression is generated by the spring shaft. The interspring is connected to the loading plate and is connected through the slider to the spring shaft. It generates an elastic force countering the displacement to the positive side in the x-direction of the connection part of the spring shaft with the loading plate.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: December 29, 2020
    Assignee: NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventor: Masato Saitoh
  • Patent number: 10772973
    Abstract: The present invention is related to a targeted type shell for drug delivery system. The object of the present invention is to provide the targeted type shell for DDS, which comprises a carbosilane dendrimer containing a silole produced by which is formed by utilizing the reaction between thiol group and alkyl halide, and a targeted protein containing a labeled proteins such as green fluorescent protein with a target recognition site. The shell may incorporate compounds having a variety of molecular weight and biopolymers, and selectively deliver them into targeted cells.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: September 15, 2020
    Assignees: QUARRYMEN & Co. Inc., Saitama University
    Inventors: Miho Suzuki, Ken Hatano, Shojiro Yoshida, Yasuhiro Yamashita
  • Patent number: 10727129
    Abstract: A substrate manufacturing method includes: a first step of disposing a condenser for condensing a laser beam in a non-contact manner on a surface 20r of a magnesium oxide single crystal substrate 20 to be irradiated; and a second step of irradiating a laser beam to a surface of the magnesium oxide single crystal substrate 20 and condensing the laser beam into an inner portion of the single crystal member under designated irradiation conditions using the condenser, and at a same time, two-dimensionally moving the condenser and the magnesium oxide single crystal substrate 20 relatively to each other, and sequentially forming processing marks to sequentially allow planar peeling.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: July 28, 2020
    Assignees: SHIN-ETSU POLYMER CO., LTD., NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY, SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Junichi Ikeno, Yohei Yamada, Hideki Suzuki, Hitoshi Noguchi
  • Patent number: 10669613
    Abstract: A titanium alloy includes 15 to 27 atomic % (at %) of tantalum (Ta) and 0 to 8 at % of tin (Sn), the balance being titanium (Ti) and unavoidable impurities, when the entire 5 amount of the titanium alloy is taken as 100 at %. Therefore, the titanium alloy provided has characteristics suitable for medical device materials, biocompatible materials, etc.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: June 2, 2020
    Assignees: NIPPON PISTON RING CO., LTD., NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Shunsuke Takeguchi, Yoshiki Ishikawa, Takasumi Kubo, Shin Ishida, Hiroki Takahashi, Masafumi Morita, Masahito Miki
  • Patent number: 10644618
    Abstract: A magnetic levitation device includes a pair of magnets, a displacement detection means, and a control means. The pair of magnets generate magnetic force for supporting a ferromagnet in a noncontact manner. The displacement detection means detect the displacement of the ferromagnet in a lateral shift direction. The control means suppresses the vibration of the ferromagnet in a lateral shift direction. The control means controls the pair of magnets so that a stronger magnetic force acts on the ferromagnet that is displaced in a direction departing from the center of the vibration than when the ferromagnet is displaced in a direction returning to the center of the vibration.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: May 5, 2020
    Assignee: NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventor: Takeshi Mizuno
  • Publication number: 20200002249
    Abstract: A method for producing an unsaturated hydrocarbon, comprising: a step of contacting a raw material gas containing an alkane with a dehydrogenation catalyst to obtain a product gas containing at least one unsaturated hydrocarbon selected from a group consisting of olefins and conjugated dienes, wherein the dehydrogenation catalyst contains at least one additive element selected from the group consisting of Na, K, and Ca, Al, Mg, a group 14 metal element, and Pt, and a content of the additive element is 0.05% by mass or more and 0.70% by mass or less based on a total mass of the dehydrogenation catalyst.
    Type: Application
    Filed: December 27, 2017
    Publication date: January 2, 2020
    Applicants: JXTG Nippon Oil & Energy Corporation, National University Corporation Saitama University
    Inventors: Hideki KUROKAWA, Tatsuya ICHIJO, Nobuhiro KIMURA
  • Patent number: 10494318
    Abstract: A method for producing a conjugated diene according to one aspect of the present invention comprises a step of contacting a raw material gas containing an alkane with a first catalyst and a second catalyst in this order to obtain a product gas containing a conjugated diene. In the production method, the first catalyst contains Sn and Pt, and a content of Sn in the first catalyst is less than 12% by mass based on the total mass of the first catalyst; and the second catalyst contains Sn and Pt, and a content of Sn in the second catalyst is 12% by mass or more based on the total mass of the second catalyst.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: December 3, 2019
    Assignees: JXTG NIPPON OIL & ENERGY CORPORATION, NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Hideki Kurokawa, Tatsuya Ichijo, Nobuhiro Kimura
  • Patent number: 10483422
    Abstract: Provided is a photovoltaic device prepared with a semiconductor including a localized level or an intermediate band in a forbidden band and capable of improving the performance than before. The photovoltaic device includes a plurality of first layers made of a first semiconducting material and a plurality of second layers made of a second semiconducting material that is different from the first semiconducting material, wherein the second semiconducting material includes a localized level or intermediate band in a forbidden band, the first layers and the second layers are alternately laminated one by one, at least two of the second layers are each disposed between a pair of the first layers, and a thickness of each of the second layers is thinner than a thickness of four molecular layers of the first semiconducting material.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: November 19, 2019
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Daisuke Sato, Hiroyuki Yaguchi, Shuhei Yagi
  • Publication number: 20190276735
    Abstract: It is an object of the present invention to provide a fine fluorescent particle, which does not cause concentration quenching and has low ecotoxicity. Specifically, the present invention relates to a fine fluorescent particle containing an AIE-active compound, the particle consisting of a network polymer, wherein the fine fluorescent particle is characterized in that the AIE-active compound is, for example, a compound represented by the following formula (1): wherein E represents silicon or germanium; R1 and R2, which are the same or different, each represent a hydrocarbon group containing 1 to 6 carbon atoms, or a substituted or unsubstituted phenyl group; and R3, R4, R5 and R6, which are the same or different, each represent a substituted or unsubstituted phenyl group.
    Type: Application
    Filed: September 26, 2017
    Publication date: September 12, 2019
    Applicant: National University Corporation SAITAMA UNIVERSITY
    Inventors: Ken Hatano, Takahiko Matsushita, Daisuke Fujikawa, Koji Matsuoka
  • Patent number: 10287612
    Abstract: Provided is a cyanobacterium improved in fatty acid productivity. A method for producing a modified cyanobacterium, comprising causing loss of function of a LexA transcriptional regulator and acyl-ACP synthetase in a cyanobacterium.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: May 14, 2019
    Assignees: Kao Corporation, Saitama University
    Inventors: Akihito Kawahara, Yukako Sonoike, Ayumi Kizawa
  • Patent number: 10280126
    Abstract: A method for producing a conjugated diene according to one aspect of the present invention comprises a step of contacting a raw material gas containing an olefin with a dehydrogenation catalyst to obtain a product gas containing a conjugated diene. In the production method, the dehydrogenation catalyst contains Al, a group 14 metal element, and Pt, and a content of the group 14 metal element in terms of oxide in the dehydrogenation catalyst is 9% by mass or more and 50% by mass or less based on the total mass of the dehydrogenation catalyst.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: May 7, 2019
    Assignees: JXTG NIPPON OIL & ENERGY CORPORATION, NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Hideki Kurokawa, Tatsuya Ichijo, Nobuhiro Kimura
  • Publication number: 20190024746
    Abstract: In the spring mechanism, the negative spring mechanism biasing the loading plate to the positive side in the z-direction has the spring shaft and interspring. The spring shaft is rotatably connected to the fixed part and is connected through the slider with respect to the loading plate so that it can rotate and can move in the x-direction. The connection part with the loading plate is positioned on the positive side in the z-direction and on the positive side in the x-direction relative to the connection part with the fixed part. An elastic force countering the compression is generated by the spring shaft. The interspring is connected to the loading plate and is connected through the slider to the spring shaft. It generates an elastic force countering the displacement to the positive side in the x-direction of the connection part of the spring shaft with the loading plate.
    Type: Application
    Filed: August 5, 2016
    Publication date: January 24, 2019
    Applicant: NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventor: Masato Saitoh
  • Publication number: 20180339953
    Abstract: A method for producing a conjugated diene according to one aspect of the present invention comprises a step of contacting a raw material gas containing an alkane with a first catalyst and a second catalyst in this order to obtain a product gas containing a conjugated diene. In the production method, the first catalyst contains Sn and Pt, and a content of Sn in the first catalyst is less than 12% by mass based on the total mass of the first catalyst; and the second catalyst contains Sn and Pt, and a content of Sn in the second catalyst is 12% by mass or more based on the total mass of the second catalyst.
    Type: Application
    Filed: March 18, 2016
    Publication date: November 29, 2018
    Applicants: JXTG NIPPON OIL & ENERGY CORPORATION, NATIONAL UNIVERSITY CORPORATION SAITAMA UNIVERSITY
    Inventors: Hideki KUROKAWA, Tatsuya ICHIJO, Nobuhiro KIMURA
  • Publication number: 20180333466
    Abstract: To provide a therapeutic agent for gastrointestinal disorder such as diabetic gastroparesis. A postprandial gastrokinetic agent containing (A) ghrelin or a ghrelin agonist and (B) motilin or a motilin agonist as active ingredients, in which both the ingredients (A) and (B) are administered so as to act on the stomach after food intake.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 22, 2018
    Applicants: ZERIA PHARMACEUTICAL CO., LTD., SAITAMA UNIVERSITY
    Inventors: Takafumi SAKAI, Ichiro Sakata, Kayuri Kuroda, Makoto Yoshimura
  • Patent number: 10006066
    Abstract: Provided is a cyanobacterium with improved productivity of fatty acid. A method for producing a modified cyanobacterium, comprising causing loss of functions of an AbrB-like transcriptional regulator and acyl-ACP synthetase in a cyanobacterium.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: June 26, 2018
    Assignees: Kao Corporation, Saitama University
    Inventors: Akihito Kawahara, Yukako Sonoike
  • Publication number: 20180163237
    Abstract: Provided is a cyanobacterium improved in fatty acid productivity. A method for producing a modified cyanobacterium, comprising causing loss of function of a LexA transcriptional regulator and acyl-ACP synthetase in a cyanobacterium.
    Type: Application
    Filed: December 21, 2015
    Publication date: June 14, 2018
    Applicants: Kao Corporation, Saitama University
    Inventors: Akihito KAWAHARA, Yukako SONOIKE, Ayumi KIZAWA