Patents Assigned to Science & Technology Corporation
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Patent number: 6590643Abstract: An apparatus is provided for measuring viewing angle characteristic of luminance and positional characteristic of a radiant object under measurement, by moving a condensing device and an imaging device relative to the object. The apparatus includes a first mechanism for moving the light receiving elements of the condensing device while keeping constant the solid angle subtended by the light receiving element at the radiant area. A second mechanism is provided for moving the imaging device in association with the condensing device, while maintaining thereon the image of the radiant area. A memory is provide. A circuit is provided for calculating viewing angle dependent and position dependent characteristics. A display device is provided for displaying radiance characteristic and distribution characteristic of the object and the result of evaluation of the calculated characteristic of luminance.Type: GrantFiled: March 27, 2001Date of Patent: July 8, 2003Assignees: Japan Science and Technology Corporation, Kumamoto Technopolis FoundationInventors: Hiroshi Kubota, Yoshiya Egashira, Tomoaki Furuse, Satoshi Hirose
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Patent number: 6589368Abstract: The present invention provides a refractory-metal-based alloy material having a remarkably enhanced toughness and strength, by internally nitriding a nitride-forming metal element incorporated as a solid solution into an alloy worked piece, which has a parent phase consisting of one element selecting from Mo, W and Cr, at a temperature equal to or lower than a recrystallization upper limit temperature of the worked piece to dispersedly yield ultra-fine nitride particles to the worked piece and thereby raise a recrystallization lower limit temperature of the worked piece, and then subjecting the internally nitrided worked piece to a second nitriding treatment at a temperature equal to or more than the raised recrystallization lower limit temperature, wherein at least in the surface region of the worked piece has a structure in which ultra-fine nitride precipitated particles are grown and stabilized with keeping the worked structure of the worked piece.Type: GrantFiled: November 21, 2001Date of Patent: July 8, 2003Assignee: Japan Science and Technology CorporationInventors: Jun Takada, Masahiro Nagae, Yutaka Hiraoka, Yoshito Takemoto
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Publication number: 20030126579Abstract: A digital integrated circuit chip is designed by identifying a logical structure to be implemented. This logical structure is represented in terms of a logical operations, at least 5% of which include selection operations. A determination is made of logic cells that correspond to an implementation of these logical operations.Type: ApplicationFiled: June 14, 2002Publication date: July 3, 2003Applicant: Science & Technology CorporationInventors: Sterling R. Whitaker, Lowell H. Miles, Eric G. Cameron
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Patent number: 6586554Abstract: This invention provides polyarylenes having a recurring unit shown by formula (I) or (II) below and a process for production thereof as well as these monomers: (wherein Ar1 and Ar2 are an arylene; R1 and R2 are C1-C20 hydrocarbon group, etc.; A1 and A2 are C1-C20 hydrocarbon group, etc.; and n is an integer of 2 or more); (wherein Ar1 and Ar2 are an arylene; R1 and R2 are C1-C20 hydrocarbon group, etc.; A1 and A2 are C1-C20 hydrocarbon group, etc.; and n is an integer of 2 or more) The polyarylenes of the invention find extensive applications as electrically conductive resins. The polyarylenes can be used also as resin compositions in a variety of formed shapes.Type: GrantFiled: January 15, 2002Date of Patent: July 1, 2003Assignee: Japan Science and Technology CorporationInventor: Tamotsu Takahashi
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Patent number: 6586555Abstract: This invention provides processes of the preparation of polyamides, polyimides, and polyamideimides, which are easy to purify after reactions, from polycarboxylic acids and polyamines in high yield without side reactions such as a change of color to black by direct polycondensation reaction with heat, especially processes of preparing aromatic polyamides (aramids), aromatic polyimides, and aromatic polyamideimides, which are difficult to synthesize in direct polycondensation reaction. Polyamides, polymides, and polyamideimides are prepared in high yield by the polycondensation of aromatic dicarboxylic acids, aromatic tetracarboxylic acids or aromatic tricarboxylic acids and aromatic diamines, using arylboric acids such as 3,4,5-trifluorophenylboric acids as polycondensation catalysts, in a mixed solvent of pentamethylbenzene and N-methylpyrrolidinone or a mixed solvent of m-terphenyl and N-butylpyrrolidinone.Type: GrantFiled: September 12, 2001Date of Patent: July 1, 2003Assignee: Japan Science and Technology CorporationInventors: Kazuaki Ishihara, Hisashi Yamamoto
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Patent number: 6582538Abstract: A molten alloy having an amorphous forming ability is pressure-solidified at a pressure exceeding one atmospheric pressure to eliminate casting defects. The cooling rate during the solidification is adjusted to disperse fine crystals having a mean crystal grain diameter of 1 nm to 50 &mgr;m and a volume percentage of 5 to 40% in an amorphous alloy ingot. In this way, a uniform residual compressive stress is imparted in the amorphous alloy ingot. Furthermore, the amorphous ingot produced by this method can be strengthened by heating it at a constant temperature rising rate to infiltrate at least one of boron, carbon, oxygen, nitrogen and fluorine from the surface of the amorphous alloy ingot in a supercooled liquid state before crystallization, to thereby precipitate a high melting point compound thereof with an element forming the amorphous alloy within the alloy ingot so as to strength the alloy.Type: GrantFiled: March 6, 2000Date of Patent: June 24, 2003Assignee: Japan Science and Technology CorporationInventors: Akihisa Inoue, Tao Zhang, Nobuyuki Nishiyama
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Patent number: 6583470Abstract: A CMOS circuit formed in a semiconductor substrate having improved immunity to total ionizing dose radiation, improved immunity to radiation induced latch up, and improved immunity to a single event upset. The architecture of the present invention can be utilized with the n-well, p-well, or dual-well processes. For example, a preferred embodiment of the present invention is described relative to a p-well process wherein the p-well is formed in an n-type substrate. A network of NMOS transistors is formed in the p-well, and a network of PMOS transistors is formed in the n-type substrate. A contact is electrically coupled to the p-well region and is coupled to first means for independently controlling the voltage in the p-well region. Another contact is electrically coupled to the n-type substrate and is coupled to second means for independently controlling the voltage in the n-type substrate.Type: GrantFiled: January 19, 2000Date of Patent: June 24, 2003Assignee: Science & Technology Corporation @ UNMInventors: Gary K. Maki, Jody W. Gambles, Kenneth J. Hass
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Patent number: 6580076Abstract: A micro-manipulation method enables micro-objects to be handled as desired with excellent repeatability when using microscopes that radiate electron beams and use secondary, reflected and transmitted electron signals to magnify objects for observation. For micro-manipulation of micro-objects with a micro-handling tool under electron beam irradiation of an electron microscope, there is a means to adjust the accelerating voltage of the electron beam, the potential of the micro-handling tool and the potential of the work substrate, thereby enabling the effective pick up and release of micro-objects with the micro-handling tool.Type: GrantFiled: May 21, 2001Date of Patent: June 17, 2003Assignee: Japan Science and Technology CorporationInventor: Hideki Miyazaki
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Patent number: 6579853Abstract: The present invention provides preparations for efficaciously administering ginsenoside Rb1 or its salt useful as cytoprotective agents. More particularly, the present invention provides pharmaceutical compositions comprising ginsenoside Rb1 or its salt for inhibiting apoptosis or apoptosis-like cell death or pharmaceutical compositions comprising ginsenoside Rb1 or its salt for promoting the expression of a cell death-inhibitory gene product Bcl-xL. Further, the present invention provides preparations for intravenous administration comprising ginsenoside Rb1 or its salt. The above pharmaceutical compositions contain ginsenoside Rb1 or its salt at low extracellular concentrations in lesion, preferably at 1 ng/ml or less and still preferably at 1 to 100 fg/ml. These compositions promote the expression of the cell death-inhibitory gene product Bcl-xL and inhibit apoptosis or apoptosis-like cell death.Type: GrantFiled: June 22, 2001Date of Patent: June 17, 2003Assignee: Japan Science and Technology CorporationInventors: Masahiro Sakanaka, Junya Tanaka, Kohji Sato
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Publication number: 20030109462Abstract: The invention provides novel naturally occurring (plant) naringenin derivatives of the general formula (I): 1Type: ApplicationFiled: May 15, 2002Publication date: June 12, 2003Applicants: Japan Science and Technology Corporation, National Institute of Agrobiological Sciences, National Food Research InstituteInventors: Kouichi Kashiwaba, Norihiko Tomooka, Duncan A. Vaughan, Akito Kaga, Hiroshi Ono, Mayumi Kameyama, Mituru Yoshida
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Patent number: 6577005Abstract: A fine particle of metal is disposed on a semiconductor substrate. With the exception of a position of disposition of the fine particle of metal, a covering layer is formed on a surface of the semiconductor substrate. Thereafter, heat treatment is implemented at a temperature higher than that where constituent atoms of the semiconductor substrate and constituent atoms of the fine particle of metal dissolve at an interface thereof due to interdiffusion in a vacuum atmosphere. Thus, a fine projection structure that comprises a semiconductor substrate and a fine projection consisting of a solid solution of the semiconductor substrate and the metal is obtained. The fine projection is formed with part thereof precipitating in the semiconductor substrate. The fine projection structure as this largely contributes in realizing high integration semiconductor devices and quantum size devices.Type: GrantFiled: June 30, 2000Date of Patent: June 10, 2003Assignees: Kabushiki Kaishia Toshiba, Japan Science and Technology CorporationInventors: Shun-ichiro Tanaka, Yutaka Wakayama
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Patent number: 6576811Abstract: The present invention provides a human c-Ha-ras proto-oncogene transgenic rat and the methods of the screening of many carcinogens and the screenings of promoters of carcinogenesis and preventive and inhibitory agents of tumors, and additionally enables the analysis of the carcinogenesis mechanism of a number of tumors.Type: GrantFiled: August 26, 1998Date of Patent: June 10, 2003Assignees: National Cancer Center Research Institute, Japan Science and Technology CorporationInventors: Hiroyuki Tsuda, Makoto Asamoto, Hiroyasu Toriyama, Takahiro Ochiya, Takeo Sekiya
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Publication number: 20030104079Abstract: The present invention provides efficacious preparations for intravenous administration, preparations for external or topical application to skin, preparations for external or topical application to mucosa or cosmetics comprising ginsenosides, in particular, ginsenoside Rb1 or its derivatives which are useful as skin tissue regeneration/reconstruction promoters or wound healing promoters; and it provides fertilizer additives comprising ginsenosides, in particular, ginsenoside Rb1 or its derivatives which are useful as plant tissue regeneration/reconstruction promoters. These preparations for intravenous administration, preparations for external or topical application to skin, preparations for external or topical application to mucosa or cosmetics are useful particularly for promoting the tissue regeneration/reconstruction in cases of incised wounds, morsus, bite wounds and/or defect of skin or mucosa or for promoting would healing.Type: ApplicationFiled: November 27, 2002Publication date: June 5, 2003Applicant: Japan Science and Technology Corporation, JapanInventors: Masahiro Sakanaka, Koji Hashimoto, Junya Tanaka, Kimihiko Nakata
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Patent number: 6573526Abstract: A single electron tunneling transistor which has a multi-layer structure exhibiting a single electron tunneling effect even with processing accuracy of not greater than 0.1 &mgr;m. The multi-layer structure of the single electron tunneling transistor is characterized by alternately growing an electrically conductive layer and a tunneling barrier layer. The number of layers is 50 or more. The structure has a minute tunneling junction having an area on the order of 1 &mgr;m square.Type: GrantFiled: April 19, 2002Date of Patent: June 3, 2003Assignee: Japan Science and Technology CorporationInventors: Tsutomu Yamashita, Sang-Jae Kim
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Publication number: 20030099998Abstract: A method for screening the effect of a segment A (chemical species A) on a substance (for example, a cell) containing DNA or RNA by using artificial chemical species. Namely, a method of detecting or identifying the function of a chemical species A on a substance containing DNA or RNA by using one or more chemical species represented by the following general formula (I) which are capable of recognizing a DNA base sequence; a kit therefor; and a plate to be used therein: B-L-A (I) wherein B represents a chemical structure containing an non-natural base capable of recognizing a DNA base sequence; A represents a chemical structure having an interaction with DNA; and L represents a linker whereby the chemical structures A and B can be linked together.Type: ApplicationFiled: November 1, 2002Publication date: May 29, 2003Applicant: Japan Science and Technology CorporationInventors: Hiroshi Sugiyama, Isao Saito, Hirokazu Iida
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Patent number: 6570893Abstract: Continuously tunable and precisely wavelength-switchable fiber lasers combine fiber Bragg gratings and the transmissive filtering properties of high finesse fiber Fabry-Perot filters. This laser arrangement adapts to multiple wavelength ranges based on the selections of fiber Bragg grating and gain medium and their arrangement to create a wavelength-modulatable and simultaneously rapidly wavelength-switchable narrow linewidth all-fiber laser design. This laser arrangement further results in narrow-linewidth outputs with fast switching speeds between the selected wavelengths.Type: GrantFiled: November 24, 1999Date of Patent: May 27, 2003Assignee: Science & Technology Corporation @ UNMInventors: Nathaniel C. Libatique, Ravinder K. Jain
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Patent number: 6571263Abstract: A random number generating apparatus which is suitable for miniaturization and which can easily generate binary random numbers that are cryptographically secure is provided. The apparatus comprises: a semiconductor device having a junction; reverse bias applying circuit for applying a reverse bias voltage of a degree so as to cause a breakdown current in the junction; and a binarizing circuit for binarizing a noise signal created in a current path including said junction for generating random numbers from the binarized signal.Type: GrantFiled: August 19, 1999Date of Patent: May 27, 2003Assignees: System Industrial Laboratory Do., LTD, Japan Science and Technology CorporationInventor: Gouichiro Nagai
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Publication number: 20030096947Abstract: A novel organic anion transporter gene participating in organic anion transport in the placenta; and an organic anion transporter which is a polypeptide encoded by the gene. A placental organic anion transporter OAT4, more particularly, a placental organic anion transporter OAT4 having the amino acid sequence represented by SEQ ID NO:2 or an amino acid sequence derived therefrom by deletion, substitution or addition of a part of the amino acids thereof. A nucleic acid (preferably DNA) having a base sequence encoding the placental organic anion transporter OAT4 or a base sequence hybridizable therewith under stringent conditions.Type: ApplicationFiled: January 9, 2003Publication date: May 22, 2003Applicant: Japan Science and Technology Corporation, JapanInventors: Hitoshi Endou, Takashi Sekine, Seok Ho Cha
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Patent number: 6565965Abstract: A metal-organic polymer composite structure comprising a microphase-separated structure from a block copolymer composed of two or more polymer chains which are incompatible with each other bonded in an end-to-end manner, wherein one of the polymer phases of said microphase-separated structure selectively contains ultrafine metal particles arranged in a row or rows. A process for producing said metal-organic polymer composite structure, which comprises (i) the step of dissolving “metal ions” and “a block copolymer comprising one or more polymer chains having an affinity for the metal and, bonded thereto in an end-to-end manner, one or more polymer chains having no or little affinity for the metal” in a mixed solvent of “a high-boiling solvent having the ability to reduce the metal ion and having a boiling point of 80 to 200° C.” and “a low-boiling solvent having a boiling point of 10 to 80° C.Type: GrantFiled: April 21, 2000Date of Patent: May 20, 2003Assignee: Japan Science and Technology CorporationInventors: Masafumi Harada, Takeji Hashimoto
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Patent number: 6566336Abstract: The invention provides a compound recognizing the minor group of hydrogen bonds between base pairs and being capable of forming a covalent bond with bases. The inventive compound can recognize a specific nucleotide sequence and can strongly bind to adjacent bases via covalent bonding, to regulate the expression of a DNA with the nucleotide sequence. The invention provides a DNA alkylating agent comprising a compound represented by the general formula I: wherein R represents a lower amyl group or a polyamide group; and X represents nitrogen or CH.Type: GrantFiled: May 30, 2000Date of Patent: May 20, 2003Assignee: Japan Science and Technology CorporationInventors: Hiroshi Sugiyama, Zhi Fu Tao, Isao Saito