Patents Assigned to Science & Technology Corporation
  • Patent number: 6417368
    Abstract: The invention provides a resin-immobilized imine represented by the following formula: P—Q—N—═CH—R   I [in the formula, P represents the principal chain of a resin polymer; Q represents a substituted or unsubstituted hydrocarbon side chain or a substituted or unsubstituted hydrocarbon side chain with a heteroatom interposed therein; R represents a substituted or unsubstituted hydrocarbon group or heterocyclic group] and a resin-immobilized &bgr;-aminocarbonyl compound of the following formula: which can be released as &bgr;-aminocarbonyl compound from the solid phase; and the invention also provide a resin-immobilized amine of the following formula: —P—Q1—O—Q2—NH2   III [Q1 and Q2 independently represent a hydrocarbon chain such as arylene, alkylenearylene or arylenealkylene], which is essential for solid state synthesis; and the invention has enabled the solid state synthesis of &bgr;-am
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: July 9, 2002
    Assignee: Japan Science and Technology Corporation
    Inventors: Shu Kobayashi, Yoji Aoki
  • Patent number: 6418190
    Abstract: A space-efficient imaging-plate-type X-ray diffraction apparatus featuring an expanded 2&thgr; goniometry range, high speed, high resolution, and design for convenient use is provided. The imaging-plate-type X-ray diffraction apparatus includes an X-ray measurement device composed of an X-ray optical system (5) and a goniometer (1) and is adapted to cause a single-crystal sample (3) to diffract X-rays. A cylindrical imaging plate (21) is disposed vertically so as to record X-rays diffracted by the sample (3), and covering a 2&thgr; goniometry range of −60° to +144°. A drive motor (11) and a transmission mechanism (12) transfer the cylindrical imaging plate vertically; and a rotary reader (20) is disposed so as to be coaxial with the transferred cylindrical imaging plate (21) and is adapted to read data of diffracted X-rays from an inner cylindrical surface of the cylindrical imaging plate (21).
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: July 9, 2002
    Assignees: Japan Science and Technology Corporation, Rigaku Corporation
    Inventors: Yutaka Yokozawa, Yuji Ohashi, Katsunari Sasaki
  • Patent number: 6416761
    Abstract: The Hantavirinae encompass a large number of species which are distributed worldwide. Although hantaviruses generally reside in murine hosts, they are also the causative agents of a number of human diseases including hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). Tissue samples were obtained from hantavirus-infected rodents (e.g., Oligoryzomys microtis) and subjected to reverse transcription-polymerase chain reaction (RT-PCR) analysis to amplify hantaviral-specific nucleic acids. A molecular clone encoding the complete nucleocapsid (N) protein of the Rio Mamore Virus (RMV) was obtained and used to express high-levels of protein. The availability of the RMV N protein and its incorporation into immunodiagnostic assays will facilitate the detection of hantavirus-specific antibodies.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: July 9, 2002
    Assignee: Science & Technology Corporation @UNM
    Inventors: Brian L. Hjelle, Norah Torrez-Martinez
  • Publication number: 20020086377
    Abstract: The present invention relates to a polypeptide comprising the amino acid sequence of SEQ ID NO: 1 or a sequence where in said amino acid sequence, one or more amino acids are deleted, replaced or added, said polypeptide having polyester synthase activity; a polyester synthase gene comprising DNA coding for said polypeptide; a recombinant vector comprising the gene; and a transformant transformed with the recombinant vector.
    Type: Application
    Filed: November 19, 2001
    Publication date: July 4, 2002
    Applicant: Japan Science and Technology Corporation
    Inventors: Yoshiharu Doi, Toshiaki Fukui, Hiromi Matsusaki
  • Patent number: 6414089
    Abstract: A method of manufacturing a polymer film having second order non-linear optical properties which has excellent stability of orientated molecules and does not become disorientated, and a polymer film and a non-linear optical element are provided. A polymer solution is placed between two substrates, which are disposed substantially perpendicular with respect to a rotating stand and substantially symmetrical with respect to a rotation axis of the rotating stand, and the rotating stand is rotated. A polymer film having second order non-linear optical properties is formed by the centrifugal force generated at the polymer solution.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: July 2, 2002
    Assignees: Riken, Japan Science and Technology Corporation
    Inventors: Hiromi Kimura-Suda, Hiroyuki Sasabe, Tatsuo Wada
  • Patent number: 6413241
    Abstract: The present invention provides a syringe comprising a syringe barrel having a plurality of non-volumetric measuring indicia thereon. The present invention also provides a container comprising: at least one chamber; a plurality of non-volumetric measuring indicia on the at least one chamber; and an opening control device in the at least one chamber for allowing liquid contained in the at least one chamber to be withdrawn from the at least one chamber.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: July 2, 2002
    Assignee: Science & Technology Corporation @UNM
    Inventor: Samuel Slishman
  • Patent number: 6407384
    Abstract: There is disclosed an energy filter capable of reducing the Boersch effect. Also, an electron microscope using this energy filter is disclosed. This energy filter is composed of a first-stage energy filter and a second-stage energy filter arranged along the optical axis of an electron beam. The length L1 of the first-stage filter is selected to be greater than the length L2 of the second-stage filter. An energy-selecting slit is positioned in the electron beam path within the free space between the first- and second-stage filters. Each of these two stages of filters is a Wien filter having mutually perpendicular electric and magnetic fields.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: June 18, 2002
    Assignees: Jeol Ltd., Japan Science and Technology Corporation, Michiyoshi Tanaka
    Inventors: Michiyoshi Tanaka, Masami Terauchi, Katsushige Tsuno, Toshikazu Honda
  • Patent number: 6403841
    Abstract: An object of the present invention is to provide a catalyst for a lower alcohol oxidation reaction which makes possible to manufacture a partial oxide of a lower alcohol such as dimethoxymethane or the like selectively and efficiently by direct oxidation of a lower alcohol such as methanol or the like, and to provide a method for manufacturing a partial oxide of a lower alcohol such as dimethoxymethane or the like selectively and efficiently from a lower alcohol such as methanol or the like by using this catalyst for a lower alcohol oxidation reaction. A partial oxide of a lower alcohol such as dimethoxymethane or the like is manufactured by subjecting a lower alcohol to vapor phase contact oxidation with a molecular oxygen-containing gas in the presence of an oxidation reaction catalyst for a lower alcohol composed of a rhenium-antimony compound oxide such as SbRe2O6 or the like. When the vapor phase contact oxidation is conducted, in particular, at a temperature of 300 to 400° C.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: June 11, 2002
    Assignee: Japan Science and Technology Corporation
    Inventors: Yasuhiro Iwasawa, Youzhu Yuan, Takafumi Shido, Nobuhiro Tamura
  • Patent number: 6395773
    Abstract: In order to provide antibacterial agents for drug-resistant bacteria and anti-Chlamydia agents, the furanonaphthoquinone derivative represented by the following formula (1): wherein each R may be the same or different, representing any one of the following (a) to (e): (wherein R′ is a hydrogen atom, alkyl group, hydroxyalkyl group, or alkoxyalkyl group), or two mutually adjacent Rs may be bonded via an oxygen atom to form a heterocyclic ring is used as the effective component.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: May 28, 2002
    Assignee: Japan Science and Technology Corporation
    Inventors: Keiichi Hirai, Kumiko Nagata, Junko Koyama, Toshio Kishimoto
  • Patent number: 6394972
    Abstract: The present invention provides a splint that may be telescopically extendable, coarsely and finely adjustable, and providing a mechanical advantage while being readily transportable. The splint may have two to three telescoping members that nest inside one another when not in use, and may be triangular, rectangular, or circular in cross section. The present invention also provides a single member adjustable splint.
    Type: Grant
    Filed: November 30, 1999
    Date of Patent: May 28, 2002
    Assignee: Science and Technology Corporation @ UNM
    Inventor: Samuel Slishman
  • Patent number: 6391611
    Abstract: The present invention relates to a polypeptide comprising the amino acid sequence of SEQ ID NO:1 or a sequence of SEQ ID NO:1 where in one or more amino acids are deleted, replaced or added, and the polypeptide having polyester synthase activity; a polyester synthase gene comprising DNA coding for the above polypeptide; a recombinant vector comprising the gene; and a transformant transformed with the recombinant vector is also provided.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: May 21, 2002
    Assignees: Japan Science and Technology Corporation, The Institute of Physical and Chemical Research
    Inventors: Yoshiharu Doi, Toshiaki Fukui, Hiromi Matsusaki
  • Patent number: 6391216
    Abstract: The invention provides a method for reactive-ion etching a magnetic material with a plasma of a mixed gas of carbon monoxide and a nitrogen-containing compound, the method comprising a step, in which a multilayered film comprising a magnetic material thin film having thereon a resist film formed on a substrate is exposed to an electron beam and then developed, to form a pattern on the resist film, a step, in which a mask material is vacuum deposited, a step, in which the resist is dissolved, to form a mask, and a step, in which a part of the magnetic material thin film that is not covered with the mask is removed by reactive ion etching with a plasma of a mixed gas of carbon monoxide and a nitrogen-containing compound, to form a pattern on the magnetic material thin film, and thus obtaining the magnetic material thin film finely worked.
    Type: Grant
    Filed: September 21, 1998
    Date of Patent: May 21, 2002
    Assignees: National Research Institute for Metals, Japan Science and Technology Corporation
    Inventor: Isao Nakatani
  • Patent number: 6389210
    Abstract: To provide a probe having an optical waveguide which is robust and highly reliable, and a method of manufacturing the same. A probe having an optical waveguide includes an optical waveguide portion having a double hetero structure and comprising an In1−x′−y′Gax′Aly′N layer (5), an In1−x−yGaxAlyN layer (4), and an In1−x″−y″Gax″Aly″N layer (3); and an AlxGa1−xN probe portion (8) grown in a conical shape on the In1−x−yGaxAlyN layer (4) of the optical waveguide portion.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: May 14, 2002
    Assignee: Japan Science and Technology Corporation
    Inventors: Koichi Mukasa, Kazuhisa Sueoka
  • Patent number: 6385479
    Abstract: The present invention provides a method for determining whether an individual has a central nervous system disease or injury comprising: obtaining a T2 measurement for at least one brain tissue sample from an individual; determining if the T2 measurement indicates the presence of a central nervous system disease or injury in the individual. The present invention also provides a method for determining whether an individual has a central nervous system disease or injury comprising: obtaining a first T2 measurement using an MRI technique for a brain tissue sample from an individual at a first time; obtaining a second T2 measurement using an MRI technique for the brain tissue sample from the individual at a second time; and comparing the second T2 measurement to the first T2 measurement.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: May 7, 2002
    Assignee: Science & Technology Corporation @ UNM
    Inventors: Wilmer L. Sibbitt, William M. Brooks, Helen Petropoulos
  • Patent number: 6383356
    Abstract: A drain joint of a pump block is opened, a piston (19a) is pushed while a piston (13a) is fixed, for charging a passage between a Luer-Lok joint (17) and an intersection part as well as a passage between the intersection part and the drain joint with a buffer. Thereafter the piston (13a) is pushed while the piston (19a) is fixed, to charge a passage (7a) with a polymer. Then, the drain joint is closed, the piston (13a) is pushed and the piston (19a) is pulled in response to the amount of pushing, for charging the passage between the intersection point and the Luer-Lok joint (17) with the polymer. Thereafter, the piston (13a) is pushed while the piston (19a) is fixed, to charge a capillary column with the polymer.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: May 7, 2002
    Assignee: Japan Science and Technology Corporation
    Inventors: Yoshihide Hayashizaki, Shin Nakamura
  • Patent number: 6380127
    Abstract: A novel metal composite is provided which is useful as a catalyst or the like by the control of a structure of an apohost and the modification thereof and in which an organic apohost capable of forming a porous structure by a hydrogen bond is compounded with at least one type of transition metallic elements or compounds thereof.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: April 30, 2002
    Assignee: Japan Science and Technology Corporation
    Inventors: Yasuhiro Aoyama, Takehisa Dewa, Tomoya Sawaki
  • Patent number: 6368889
    Abstract: An object is to provide a variable-wavelength light-emitting element which employs a direct gap semiconductor having a magnetic moment for a semiconductor layer serving as an active layer, so that the semiconductor has reduced crystal distortion and stable characteristics as the active layer of the light-emitting element, as well as a method of fabricating the variable-wavelength light-emitting element. A semiconductor silicide or a semiconductor silicide doped with transition metal is used to form an active layer (&bgr;-FeSi2 transformed into spheres) (2″) of a semiconductor light-emitting element, and the active layer is sandwiched between p-type and n-type semiconductor layers forming a pn junction, the p-type and n-type semiconductor layers having a forbidden bandwidth greater than that of the semiconductor silicide.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: April 9, 2002
    Assignee: Japan Science and Technology Corporation
    Inventor: Takashi Suemasu
  • Patent number: 6368713
    Abstract: Hollow carbon microcoils are provided having a pitch that is substantially zero. Also provided are ceramic microcoils comprising a metal nitride, a metal carbide or a metal carbonitride. The invention also includes methods for producing such microcoils.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: April 9, 2002
    Assignee: Japan Science and Technology Corporation
    Inventor: Seiji Motojima
  • Patent number: 6365744
    Abstract: A process for producing a pyridine derivative, which comprises reacting an azametallacyclopentadiene represented by formula (1) with an alkyne in an organic solvent containing a complex of a transition metal such as Ni(II). (In formula (1), M represents an early transition metal, e.g., Zr, Ti or Hf; L represents cyclopentadienyl, indenyl, fluorenyl, hydrocarbon-oxy, amide, acetylacetonato, or carboxy group, a phosphine ligand, an amine ligand, an ether ligand, or a ligand comprising two or more these bonded to each other through appropriate crosslinking group; n is an integer of 1 to 4; and R1, R2, R3, R4 and R5 each represents C1-20 (substituted) alkyl, alkenyl, an aromatic group, silyl, alkoxy, or an ester group.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: April 2, 2002
    Assignee: Japan Science & Technology Corporation
    Inventor: Tamotsu Takahashi
  • Patent number: D458186
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: June 4, 2002
    Assignee: Japan Science and Technology Corporation
    Inventor: Hiroshi Shimizu