Abstract: Methods are provided for treating or preventing human immunodeficiency virus-1 (HIV-1) or human immunodeficiency virus-2 (HIV-2) in a virologically suppressed patient in need thereof comprising switching the patient from an antiretroviral treatment regimen comprising at least three antiretroviral agents to a treatment regimen comprising only two antiretroviral agents. In one aspect the two treatment regimen consists of dolutegravir, rilpivirine and at least one pharmaceutically acceptable excipient, diluent or carrier. In another aspect of the invention, there is provided a multilayer tablet comprising dolutegravir or a pharmaceutically acceptable salt thereof and rilpivirine or a pharmaceutically acceptable salt thereof.

Abstract: According to one embodiment, a superconducting coil apparatus comprising at least one superconducting coil formed of a plurality of turns under a definition that one turn is a portion of a superconducting wire annularly wound for one round, wherein: the superconducting coil has a shape along an outer peripheral surface of a tubular structure having a tubular shape; each of the plurality of turns has a coil longitudinal portion extending along an axial direction of the tubular structure; arrangement form of the coil longitudinal portion is different between a main magnetic field generation region configured to generate a main magnetic field and a magnetic field correction region configured to generate a correction magnetic field.

Abstract: A method for selectively or preferentially reducing the amount of Fe ions available to cancer cells involves introducing to an area of the body which contains cancer cells an effective amount of an aqueous, pH buffered composition that includes dissociation products of a soluble weak acid and a salt of a weak acid. When the amount of arriving Fe ions falls below a first threshold, the cancer cell no longer can proliferate. When the amount of arriving Fe ions falls below a second threshold, the cancer cell dies.

Abstract: The present disclosure pertains to the field of health monitoring technologies, and discloses a life early warning system based on sensor acquisition, including a sign sensor, a camera, a location analysis module, an attachment location correction module, a sign detection module, an alarm feedback module, a detection optimizer, a medical comparison library, a medical platform, and a client, where the sign sensor is configured to attach to a specified location of a user body, and acquire user sign information in real time. In the present disclosure, a location of the sign sensor is analyzed by using a cascade network, which can ensure accuracy of an attachment location of each sensor, avoid reduction in precision of subsequent detection due to a sensor location abnormality, greatly improve detection accuracy, further prevent an abnormal sign report due to misusing by a child, and improve user experience.

Abstract: A disclosed polymer thin film includes a cationic polymer having a hydrolyzable side chain. The polymer thin film has a surface potential of 1 mV to 50 mV. A hydrolysis efficiency of the cationic polymer is 30% or more after reaction at 50° C. for one hour. The cationic polymer is dissolved to three-dimensionally capture nucleic acids, and releases the nucleic acids through hydrolysis. Thus, nucleic acid capturing-releasing efficiency can be improved.

Abstract: Provided is a memcapacitor. The memcapacitor includes: a first electrode having a metal-doped perovskite composition; a second electrode disposed on the first electrode; and a dielectric thin film having a perovskite composition, disposed between the first electrode and the second electrode, and having a variable dielectric constant depending on a voltage between the first electrode and the second electrode.

Abstract: Systems and methods are described herein to implement transverse momentum injection at low frequencies to directly modify large-scale eddies in a turbulent boundary layer on a surface of an object. A set of transverse momentum injection actuators may be positioned on the surface of the object to affect large-scale eddies in the turbulent boundary layer. The system may include a controller to selectively actuate the transverse momentum injection actuators with an actuation pattern to affect the large-scale eddies to modify the drag, fluid mixing, heat transfer, and/or other interactions of the fluid flow with the surface. In various embodiments, the transverse momentum injection actuators may be operated at frequencies less than 10,000 Hertz.

Abstract: Provided are a method and apparatus for processing map information, a device, and a storage medium which relate to the field of computer technology and, in particular, to the fields of intelligent transportation and computer vision technology. The specific implementation includes that an object in an image for query is recognized to obtain an object recognition result and that a target point of interest matching the image for query is selected from at least one candidate point of interest of an electronic map according to the object recognition result.

Abstract: A spatial position-dependent I/Q domain modulation method, dual domain modulation method and multiple access communication method are provided. The methods eliminate the dependence of physical layer secure communication on channel state information, and realize the function that a receiver at an expected position can communicate normally, while an eavesdropper at other positions cannot receive a signal or can only receive a wrong signal. The security capability of a wireless communication system is improved from the spatial dimension. The multiple access communication method can realize the distinguishing of multiple users according to precise spatial position points. Even if a plurality of users are located in the same sector in an angular domain, as long as the spatial positions of these users are different, the method can be used to perform multiple access communication, thereby further improving the spatial multiplexing rate of the system and increasing the system capacity.

Abstract: The present disclosure provides a method and system for processing an obstacle detection result of an ultrasonic sensor array. The method comprises: obtaining obstacle coordinates collected by ultrasonic sensors in an ultrasonic sensor array; inputting the obstacle coordinates collected by ultrasonic sensors in the ultrasonic sensor array into a pre-trained neural network model, to obtain true or false labels for the obstacle coordinates collected by the ultrasonic sensors output by the pre-trained neural network model; process the obstacle coordinates collected by the ultrasonic sensors in the ultrasonic sensor array according to the true or false labels. The present disclosure improves the accuracy in the obstacle detection of the ultrasonic sensor array, avoids detection error and omission and improves the driving safety.

Abstract: Disclosed are a separator for fuel cells capable of minimizing the volume of a system and the use of sealants, and a stack for fuel cells, more particularly, a stack for solid oxide fuel cells, including the same. Specifically, by adding a metal sheet having a specific shape, position and size to the separator, the stress applied to the sealant can be uniformized, and thus the oxidizing agent and fuel can be separated and electrically isolated using only a piece of sealant. Therefore, the stack for fuel cells is characterized in that there is no variation in temperature, reactant concentration, power, or the like between respective unit cells, so delamination and microcracks do not occur, the volume is minimized, and the power density per unit volume is very high.

Abstract: One example method for improving the efficiency of robotic surgical procedures by integrating applications into the surgeon console user interface is presented. The method includes generating a surgeon console user interface for displaying at a surgeon console associated with a robotic surgical device during a robotic surgical procedure. The surgeon console user interface includes a main region configured for displaying a video signal of the robotic surgical procedure, a left side region for displaying data related to the surgical tools controlled by a left hand controller; and a right side region for displaying data related to the surgical tools controlled by a right hand controller. The method further includes displaying the graphical user interface on a display device of the surgeon console and integrating applications into the surgeon console user interface in response to determining that the surgeon console switches to an application mode.

Abstract: The present disclosure provides an ultrasonic radar array, an obstacle detection method and system. The method includes: obtaining obstacle information collected by ultrasonic radars in an ultrasonic radar array in an obstacle scenario; judging false detection and missed detection for the obstacle information collected by ultrasonic radars according a preset rule; processing the obstacle information collected by the ultrasonic radars according to the judgement result; determining a position of the obstacle according to the processed obstacle information collected by the ultrasonic radars.

Abstract: Individual-specific changes in health conditions are detected using a latent space mapping generated from baseline physiological data collected in a longitudinal study of the individual. Historical baseline data in an n-dimensional input space is modeled into a k-dimensional latent space, where k<n. The mapping for the model is then used to convert new physiological data into a latent space point, which can be used to determine if the associated newly collected physiological data is anomalous and thus indicative of a change in health condition. Anomalies can be inferred from poor fit between the point and baseline data within the latent space, or form large error between data reconstructed into the input space from the point and the original new physiological data.

Abstract: A data storage medium is disclosed comprising a solid support matrix including an optional stabilising reagent or reagents in a dry form, for use as a support for artificially synthesised oligonucleotide sequences encoded with data. Preferably the matrix is fibrous (for example cellulose, or glass, fibres) formed into a support of sufficient strength to hold the oligonucleotide sequences. The stabilising reagents are preferably a combination of a weak base, and a chelating agent, optionally, uric acid or a urate salt, and optionally an anionic surfactant.

Abstract: The present invention relates to a quantum computing unit comprising a superconducting substrate or other superconducting component, at least three outer Majorana modes, and at least one inner Majorana mode, wherein the at least three outer Majorana modes are located along an outer perimeter, and wherein the at least one inner Majorana mode is located within the outer perimeter. This spatial configuration of the four participating Majorana modes allows to control the time-dependent coupling between the respective Majorana modes. The related quantum gates can be performed perfectly in a finite time, preferably with a frequency of up to several GHz. These include the braiding gate, the ?/8 magic phase gate, the ?/12 phase gate, and, for multi-qubit systems, the CNOT gate. The robustness of the mechanism guarantees that for special times the quantum gate is conducted the quantum gate is perfectly realized. This property is independent of material specific parameters.

Abstract: The present disclosure is concerned with 2-pyrimidone compounds that are capable of inhibiting a viral infection and methods of treating alphavirus viral infections such as, for example, chikungunya, Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), and Venezuelan equine encephalitis using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Provided herein is a compound of formula I: and the use thereof for detecting the presence of hydrogen sulfide in cells or tissues in vitro or in vivo. The detecting may be useful, for example, in diagnosing cancer or other diseases related to imbalanced hydrogen sulfide (H2S) production such as neurodegenerative diseases.

Abstract: A method, apparatus and a system for thermally-assisted pulsed electromagnetic field stimulation for treatment of osteoarthritis in the knee are disclosed. A multi-coil applicator is adapted for positioning around the knee. A first coil is positioned on the top of the knee and provides electric field stimulation in the plane of the patella to stimulate the patella cartilage. Second and third coils are rectangular coils wrapped up below and above the knee respectively. The coils in the wrapped position generate a magnetic field along the knee axis and provide high amplitude of the electric field stimulation of the femoral and tibial cartilages in the plane of tibial plateau. Resistive heaters and free wheel diodes can be provided to the applicator to supply uniform thermal stimulation around the knee joint.

Abstract: The present disclosure relates to a magnon spin valve device, a magnon sensor, a magnon field effect transistor, a magnon tunnel junction and a magnon memory. A magnon spin valve device may comprise a first ferromagnetic insulation layer, a non-magnetic conductive layer disposed on the first ferromagnetic insulation layer, and a second ferromagnetic insulation layer disposed on the non-magnetic conductive layer.