Abstract: The present invention relates to a composition for preventing or treating a neuroinflammatory disease, which can inhibit the expression of neuroinflammatory cytokines, promote the degradation of amyloid beta, and improve a cognitive function in an animal model of Alzheimer's disease. More specifically, the present invention relates to a composition for preventing or treating a neuroinflammatory disease comprising didanosine or a pharmaceutically acceptable salt thereof, and the composition may be used for the development of drugs and quasi-drug materials.

Abstract: The present disclosure is directed towards systems and methods that leverage machine-learned models to decrease the rate at which abnormal sites are missed during a gastroenterological procedure. In particular, the system and methods of the present disclosure can use machine-learning techniques to determine the coverage rate achieved during a gastroenterological procedure. Measuring the coverage rate of the gastroenterological procedure can allow medical professionals to be alerted when the coverage output is deficient and thus allow an additional coverage to be achieved and as a result increase in the detection rate for abnormal sites (e.g., adenoma, polyp, lesion, tumor, etc.) during the gastroenterological procedure.

Abstract: The disclosure relates to a method for simulating intraplate volcanism. A technical solution is: mixing 47-60 wt % of calcium oxide powder, 35 wt % of alumina powder and 5-18 wt % of silica powder uniformly to obtain a mixed powder; putting the mixed powder in a corundum crucible, placing the crucible in a high-temperature furnace provided with an observation window outside which an industrial camera with a depression angle of 30-45° is provided, heating to 1,500-1,900° C. at a rate of 1-30° C./min under an air atmosphere at a normal pressure, holding for 0.5-5 h; recording intraplate volcanism formed by upwelling of a melt of the mixed powder along an inner wall of the crucible during the holding with the industrial camera to obtain a simulated process of the intraplate volcanism.

Abstract: A technique for generating and presenting context-aware recommendations to assist a patient in managing a chronic health condition. A health management platform provides various services that are accessible to a patient via a graphical user interface (GUI). Input data are received from various services and processed to generate contextual data associated with the patient such as a health state of the patient. Using the contextual data, a recommendation to access a particular service is generated and presented to the patient via the GUI. For example, in response to determining a health state of a patient, a recommendation to access a service to improve the health state of the patient can be automatically presented via the GUI to encourage the patient to access the service.

Abstract: A transient blockchain proxy server consolidates many individual requests to add data to a blockchain by aggregating hashed data from these requests and sending the aggregated hashed data to the blockchain network as a single request. The blockchain network adds a new block to the blockchain with the aggregated hashed data and returns a transaction identifier for the new block to the transient blockchain proxy server, which passes the transaction identifier back to all the requestors who then can directly use the blockchain network to verify the hashed data using the transaction identifier. The transient blockchain proxy server buffers all incoming requests until one of the pending requests reaches a send timepoint that is the blockchain network delay plus a buffer time before a guaranteed time of verification. All incoming requests are then consolidated and sent as a single transaction to the blockchain network. Tiered verification-time services are enabled.

Abstract: The present invention relates to novel combinations, which are useful in the treatment of tuberculosis.

Abstract: The present invention relates to an antiviral application of nucleoside analogs. Specifically, the present invention relates to uses of nucleoside analogs and a pharmaceutical composition thereof as: (a) inhibitors for inhibiting the replication of coronaviruses, influenza viruses, respiratory syncytial viruses, flaviviridae viruses, filoviridae viruses and/or porcine epidemic diarrhea virus (PEDV); and/or (b) medicines for treating and/or preventing and mitigating diseases caused by coronavirus, influenza virus, respiratory syncytial virus, flaviviridae virus, filoviridae virus and/or porcine epidemic diarrhea virus (PEDV) infections. The nucleoside analogs according to the invention may treat and/or prevent and mitigate respiratory infection, pneumonia (COVID-19) and other related diseases caused by 2019 novel coronavirus infection.

Abstract: The present disclosure relates to a fine particle-trapping sensor including: a plasmonic hotspot layer formed of a first metal; and a trapping layer formed of a second material. The inventors of the present disclosure have made extensive research efforts to develop a more effective and novel sensor for the real-time and high-sensitivity detection of droplets emitted from the oral cavity. As a result, the inventors have developed an alloy composite nanostructure including a Raman sensor layer, formed of a metal, and a trapping layer formed of a dielectric material, and have found that, when the ratio between the two layers is adjusted, the alloy composite nanostructure effectively traps respiratory droplets rapidly emitted from the oral cavity and detects coronavirus (SARS-CoV-2 lysate) in the respiratory droplets at a concentration of 10 pfu/ml, indicating that the composite nanostructure may be very advantageously used in the field of fine particle trapping.

Abstract: One example method for improving the efficiency of robotic surgical procedures by integrating applications into the surgeon console user interface is presented. The method includes generating and displaying a first graphical user interface at a surgeon console associated with a robotic surgical device during a robotic surgical procedure, and detecting a combination of user actions through control devices of the surgeon console. The method further includes responsive to detecting the combination of the user actions, causing surgical tools of the robotic surgical device to be locked and generating and displaying a second graphical user interface at the surgeon console which includes user interfaces of applications and is configured to be interactive through the control devices. The method further includes detecting a user action to exit the application mode, causing the surgical tools to be unlocked, and updating and displaying the first graphical user interface at the surgeon console.

Abstract: This disclosure relates to method and system for validating an Autonomous Vehicle (AV) stack. The method may include receiving an Operational Design Domain (ODD) and real-world data for evaluating at least one of an Advanced Driver Assistance System (ADAS) and the AV. The ODD is based on at least one feature of at least one of the ADAS and the AV. For each of a plurality of iterations, the method may further include generating a driving scenario based on the ODD of the AV and the real-world data through a Quality of Ride Experience (QoRE)-aware cognitive engine, plugging and running at least one of the ADAS and the AV algorithm based on the driving scenario, and determining a set of performance metrics corresponding to the at least one feature of at least one of the ADAS and the AV in the driving scenario based on the simulating.

Abstract: A method for vacuum heat treating Nb, such as is used in superconducting radio frequency cavities, to engineer the interstitial oxygen profile with depth into the surface to conveniently optimize the low-temperature rf surface resistance of the material. An example application is heating of 1.3 GHz accelerating structures between 250-400° C. to achieve a very high quality factor of 5×1010 at 2.0 K. With data supplied by secondary ion mass spectrometry measurements, application of oxide decomposition and oxygen diffusion theory was applied to quantify previously unknown parameters crucial in achieving the oxygen alloy concentration profiles required to optimize the rf surface resistance. RF measurements of vacuum heat treated Nb superconducting radio frequency cavities confirmed the minimized surface resistance (higher Q0) previously expected only from 800° C. diffusive alloying with nitrogen.

Abstract: Provided are a method for fabricating a highly elastic porous polymer membrane, a method for manufacturing a cell culture system using a porous polymer membrane fabricated by the fabrication method, and a cell culture system manufactured by the manufacturing method. The porous polymer membrane can be fabricated by spin coating a mixture solution containing a biodegradable elastomeric polymer and a water-soluble moisture absorbent in an optimum ratio while maintaining a high relative humidity. The porous polymer membrane has a uniform thickness and a uniform pore size and is highly elastic. In addition, the thickness and pore size of the porous polymer membrane can be controlled. The porous polymer membrane can induce active cell-cell interaction during cell co-culture due to its high porosity. The porous polymer membrane enables control over cell alignment or array due to its high biocompatibility and elasticity.

Abstract: An imaging system includes a light source to emit a plurality of wavelengths of light, and a camera coupled to receive the light reflected back from tissue in a body. Also included are a database with reflectance data for a plurality of tissue types, and a controller coupled to the light source, the database, and the camera. The controller causes the imaging system to perform operations, including: generating image data with the camera; receiving the image data from the camera with the controller; comparing, with the controller, the image data to the reflectance data in the database; and determining a tissue type in the image data in response to comparing the image data to the reflectance data.

Abstract: To provide an active-energy-ray-curable composition including a compound represented by General Formula (I) below: where in the General Formula (I), R is hydrogen or a methyl group; A is a structure expressed by one selected from the group consisting of Structural Formulas (II) to (VII) below, each of which may have a substituent such as an alkyl group or an alkoxy group, or both; j and k in the Structural Formulas (VI) and (VII) are an integer of 0 or more; X denotes a substituent including a heteroatom; n is an integer of 0 or more, m is an integer of 1 or more, and n+m is 3 or more, or n is an integer of 0 and m is an integer of 2; and wavy lines in the Structural Formulas (II) to (VII) each independently denote a bond with X or a (meth)acryloyl group (H2C?CR—C(?O)—):

Abstract: The exemplary embodiments described herein are related to techniques for automatically generating narratives about data based on communication goal data structures that are associated with configurable content blocks. The use of such communication goal data structures facilitates modes of operation whereby narratives can be generated in real-time and/or interactive manners.

Abstract: A soil conditioner spreader and an operation method thereof are provided. The soil conditioner spreader includes a spreader body, a ridger, a solid tank, two spiral drills, a rotary tillage wheel and a mulching device, where the spreader body is provided with a hopper in a front part. The hopper stores a conditioner. The solid tank is arranged above the spiral drills. The spreader body is connected to the solid tank through a feeding track. The ridger, the spiral rills, the rotary tillage wheel and the mulching device are successively arranged at the bottom of the spreader body from the rear to the front. The ridger ridges first, and then the spiral drills perform deep plowing, rotary tillage and scarification and apply the conditioner to a ridge. The rotary tillage wheel performs rotary tillage, and a nozzle sprays a nutrient solution or an herbicide/insecticide. Finally, the mulching device mulches.

Abstract: Provided is a steam jet multifunctional aircraft deicing vehicle with steam jet, includes a vehicle body, where a steam generating assembly is arranged in the vehicle body, and the steam generating assembly is connected with a steam conveying assembly. A moving assembly is rotatably connected above the vehicle body, and the moving assembly is rotatably connected with an execution assembly. The execution assembly includes a first spray head assembly and a second spray head assembly. The steam conveying assembly includes a first supercharger and a second supercharger arranged side by side, where an air outlet end of the first supercharger is communicated with one end of a first air outlet pipe, and an other end of the first air outlet pipe is communicated with spray heads of the second spray head assembly through a first air pipeline.

Abstract: Disclosed is a method for measuring gas pressure of a close-distance seam group simultaneously, including the following steps: constructing a pressure-measuring drill hole inclined downwards; lowering a first seam piezometer tube, lowering a baffle and a polyurethane blocking material after a tube head reaching a lowermost seam; and installing a gas pressure gauge; lowering a second seam piezometer tube, lowering the baffle and the polyurethane blocking material after the tube head reaching a second layer of seam; and installing the gas pressure gauge; lowering a nth seam piezometer tube, lowering the baffle and the polyurethane blocking material after the tube head reaching a nth layer of seam; and installing the gas pressure gauge; injecting a high-water and quick-solidifying material into the drill hole; and connecting the gas pressure gauges through optical fibers, and connecting the gas pressure gauges with a ground control system.

Abstract: A spin state readout device of a quantum sensor. The quantum sensor has spin-manipulable electrons. The spin state readout device includes: a pumping unit configured to emit a first laser to the quantum sensor to polarize the electron spin state of the quantum sensor; a probing unit configured to emit a second laser to the quantum sensor to make the spin-polarized quantum sensor in an excited state; a signal receiving unit configured to receive fluorescence photons emitted from the quantum sensor and convert optical signals into electrical signals; and a timing unit coupled to the probing unit and the signal receiving unit and configured to time an excited state lifetime of the quantum sensor. The spin state readout device of the quantum sensor provided can reduce spin state reading errors caused by laser power drifts, system signal collection efficiency drifts and the like.

Abstract: An exhaust system for an industrial washer is proposed. The exhaust system comprises a conduit that can be coupled to an exhaust air outlet of a washer. A condenser is coupled to the conduit and configured to cool and to extract humidity from the exhaust air. A filter housing with removable filter is connected to the condenser and configured to filter said exhaust air. A fan with an exhaust outlet is connected to the filter housing. A controller is configured to control at least the fan to extract the exhaust air from the washer outlet through the conduit, condenser and filter housing and to eject dried and cooled exhaust air from said exhaust outlet. By reducing the humidity and temperature of the exhaust air, the condenser improves the efficacy and lifetime of the filter. The effective and reliable removal of contamination is thus ensured while the need to further process the waste air is obviated.