Abstract: An irregular seismic data collection method is based on forward modeling. The method includes: fully collecting geological information of a work area to build a geological model, determining arrangement parameters of receiver points and shot points for regular high-density collection and irregular sparse collection, performing irregular optimization design on positions of the shot points based on forward modeling, performing irregular optimization design on positions of the receiver points based on forward modeling, and outputting a preferred irregular sparse observation system.
Type:
Grant
Filed:
March 23, 2023
Date of Patent:
March 19, 2024
Assignee:
Institute of Geology and Geophysics, Chinese Academy of Sciences
Abstract: The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.
Type:
Grant
Filed:
June 21, 2022
Date of Patent:
March 19, 2024
Assignee:
Gilead Sciences, Inc.
Inventors:
Michael Graupe, Juan A. Guerrero, Stephen D. Holmbo, Jesse M. Jacobsen, Tetsuya Kobayashi, Leena B. Patel, Heath A. Weaver, Jie Xu, Suet C. Yeung
Abstract: Disclosed herein are modified zeolites and methods for making modified zeolites. In one or more embodiments disclosed herein, a modified zeolite may include a microporous framework including a plurality of micropores having diameters of less than or equal to 2 nm. The microporous framework includes at least silicon atoms and oxygen atoms. The modified zeolite may further include organometallic moieties each bonded to bridging oxygen atoms. The organometallic moieties include a hafnium atom. The hafnium atom is bonded to a bridging oxygen atom, and bridging oxygen atom bridges the hafnium atom of the organometallic moiety and a silicon atom of the microporous framework.
Type:
Grant
Filed:
January 26, 2023
Date of Patent:
March 19, 2024
Assignees:
King Abdullah University of Science and Technology, Saudi Arabian Oil Company
Inventors:
Robert Peter Hodgkins, Omer Refa Koseoglu, Jean-Marie Maurice Basset, Kuo-Wei Huang, Anissa Bendjeriou Sedjerari, Manoj K. Gangwar, Sathiyamoorthy Murugesan
Abstract: A medical device is provided that can be held and operated with a single hand to cause a catheter to be placed at a selected location in a patient's body. The user's other hand is free to perform other tasks, such as operating an ultrasound probe, for example. The medical device may also include a valve that can be operated with the same hand that holds the medical device to open a port to cause a fluid, such as a nerve block agent, for example, to be injected into the patient's body at the selected location.
Abstract: Disclosed is a magnetic parameter value estimation method using deep learning, the magnetic parameter value estimation method including creating a simulated magnetic domain image corresponding to a spin configuration of a two-dimensional magnetic system created through computer simulation, modeling a deep neural network using the simulated magnetic domain image, and estimating a magnetic parameter value of an observed magnetic domain image using the modeled deep neural network.
Type:
Grant
Filed:
October 16, 2020
Date of Patent:
March 19, 2024
Assignee:
Korea Institute of Science and Technology
Abstract: The present invention belongs to the field of environment monitoring, particularly relates to a CO2 storage state networking monitoring device, system and method with multi-information fusion. The present invention comprises: obtaining orientation electrical signal data and real-time pressure signals, analyzing a fluid flowing state at a view of a pressure sensor through the real-time pressure signals, and obtaining a CO2 flowing state through the orientation electrical signal data; and obtaining a CO2 regional storage state by combining an orientation CO2 content, a CO2 flowing state and the fluid flowing condition at the view of the pressure sensor. By combining accurate short-range CO2 boundary monitoring of orientation electrodes with long-range monitoring of pressure sensors to achieve a wide range of CO2 flowing state monitoring, the present invention can observe more data with higher reliability and effectively aims at the problem of strong inter-well heterogeneity.
Type:
Grant
Filed:
August 1, 2022
Date of Patent:
March 19, 2024
Assignee:
Institute of Geology and Geophysics, Chinese Academy of Sciences
Inventors:
Wang Zhang, Fei Tian, Yongjian Zhou, Wenhao Zheng, Yongwen Yang
Abstract: The present disclosure generally relates to methods of treating or preventing cancer by administering an MCL-1 inhibitor and an antibody-drug conjugate, and optionally one or more additional anti-cancer agents. In particular, the MCL-1 inhibitor can be a compound of formula (I), (II) or (III), or compound A. The antibody-drug conjugate can comprises an anti-Trop-2 antibody and an anti-cancer agent (e.g., SN-38). The combination therapy for treating cancer can have synergistic effect.
Type:
Grant
Filed:
June 9, 2022
Date of Patent:
March 19, 2024
Assignee:
Gilead Sciences, Inc.
Inventors:
Thomas F. Kenney, Clinton K. Matson, Chandrasekar Venkataramani
Abstract: A high-dimensional non-orthogonal transmission method is provided. In the method, signals of various users are mapped to form high-dimensional signals, and the high-dimensional signals are pre-coded, such that non-orthogonal transmission is realized in a higher dimension. Moreover, different users perform matched receiving on respective signals, and non-orthogonal transmission signals can be recovered merely by means of a receiver with a linear complexity. By means of the method, multi-user data non-orthogonal transmission can be realized without depending on conditions such as user pairing and collaboration, and various users do not need to perform iterative feedback, such that the detection complexity of non-orthogonal multi-user signals is significantly reduced.
Type:
Grant
Filed:
April 29, 2021
Date of Patent:
March 19, 2024
Assignee:
University of Electronic Science and Technology of China
Abstract: The invention relates to a method for computationally designing a number of re-usable two-pieced molds for the reproduction of an object, wherein each mold is fillable with filling material, in particular resin, to form the object or a part of the object to be reproduced, wherein each mold consists of rigid material.
Type:
Grant
Filed:
June 21, 2019
Date of Patent:
March 19, 2024
Assignee:
Institute of Science and Technology Austria
Inventors:
Bernd Bickel, Thomas Auzinger, Kazutaka Nakashima, Takeo Igarashi
Abstract: A handheld luminometer system and assembly are shown and described. In one embodiment, an assembly includes a portable luminometer and a front end platform having a microcontroller circuit to communicate with a host device. Typically, the portable luminometer includes a sample port to accept a test sample holder, a photomultiplier assembly with at least one photomultiplier tube, and a base. The result is a luminometer assembly for use with a single-use test sample holder in communication with a host device.
Abstract: A method of detecting Factor VIII level in a subject, particularly in a subject in need of treatment with at least one Factor Xa inhibitor. The method comprises (a) selecting at least one subject in need of treatment with at least one Factor Xa inhibitor; and (b) detecting Factor VIII level in a sample obtained from the at least one subject with the aim to determine an appropriate dosage of the at least one Factor Xa inhibitor. Preferably, the method comprises a further step of administering at least one Factor Xa inhibitor to the subject.
Abstract: Disclosed is a self-powered formaldehyde sensing device, comprising: a triboelectric material electrode layer including a first substrate and a first electrode layer formed on the first substrate; a triboelectric material dielectric layer including a second substrate, a second electrode layer formed on the second substrate, a dielectric reacting layer formed on the second electrode layer, and a reaction modification layer formed on the dielectric reacting layer to surface-modify the dielectric reacting layer, the reaction modification layer being a phosphomolybdic acid complex (cPMA) layer, the phosphomolybdic acid complex of the phosphomolybdic acid complex layer being obtained by dissolving 4,4?-bipyridine (BPY) in isopropanol (IPA) and then mixing with phosphomolybdic acid (PMA) solution; an elastic spacer; and an external circuit.
Type:
Application
Filed:
December 21, 2022
Publication date:
March 14, 2024
Applicant:
National Taiwan University of Science and Technology
Abstract: The present disclosure provides a method and device for intelligent control of heating furnace combustion based on a big data cloud platform, which relates to the technical field of artificial intelligence control. The method includes: construction of big data cloud platform based on production and operation parameters of the heating furnace; identification of key factors in the production process of the heating furnace by using big data mining technology; independent deployment of traditional heating furnace combustion control systems based on the mechanism model; and integration of cloud platform big data expert knowledge base and the heating furnace combustion intelligent control system.
Type:
Application
Filed:
September 7, 2023
Publication date:
March 14, 2024
Applicant:
University of Science and Technology Beijing
Inventors:
Qing LI, Fengqin LIN, Hui LI, Li WANG, Chengyong XIAO, Xu YANG, Jiarui CUI, Chunqiu WAN, Qun YAN, Yan LIU, Lei MIAO, Jin GUO, Boyu ZHANG, Chen HUANG, Yaming XI, Yuxuan LIN
Abstract: Provided herein are chassis for use in injection systems configured to penetrate a plant and distribute a liquid formulation to the plant, and the method of using the chassis.
Type:
Application
Filed:
January 28, 2022
Publication date:
March 14, 2024
Applicant:
Invaio Sciences International GmbH
Inventors:
Antony Mathai CHETTOOR, Michael Christian OEHL, Urs WIDMER
Abstract: A method for detecting adsorption performance of microplastics for heavy metals using low-field NMR relaxation method, including: establishing a reference line reflecting a relationship between a target heavy metal ion concentration and a transverse relaxation time; conducting a heavy metal adsorption experiment on microplastics and obtaining samples at different time points; detecting transverse relaxation times of the multiple samples obtained; determining a heavy metal ion concentration of each sample based on the reference line of the target heavy metal ion concentration and the transverse relaxation time; analyzing data and implementing a model fitting process. The method according to the present disclosure does not require cumbersome and complicated sample pre-processing, it can be measured immediately after sampling, it is simple, fast and low-cost, the method has a wide detection limit, the detection is faster, non-destructive testing can be achieved.
Type:
Application
Filed:
October 19, 2023
Publication date:
March 14, 2024
Applicant:
Institute of Geology and Geophysics, Chinese Academy of Sciences
Abstract: A Software-as-a-Service infrastructure is provided to perform data analytics, wherein a given analytic is defined in a spreadsheet according to a formula, and wherein the formula is associated with an Environmental, Social and Governance (ESG) impact. The infrastructure comprises program code configured to receive a request, determine whether the request is associated with data of a first type and, if so, to clone the spreadsheet. The code is further configured to receive results from execution of the spreadsheet with respect to given data, and to provide the results for display in response to the request. The spreadsheet executes independently of execution of the computer program code.
Abstract: Embodiments of the present disclosure relate to zeolites and method for making such zeolites. According to embodiments disclosed herein, a zeolite may have a microporous framework including a plurality of micropores having diameters of less than or equal to 2 nm and a plurality of mesopores having diameters of greater than 2 nm and less than or equal to 50 nm. The microporous framework may include an MFI framework type. The microporous framework may include silicon atoms, aluminum atoms, oxygen atoms, and transition metal atoms. The transition metal atoms may be dispersed throughout the entire microporous framework.
Type:
Application
Filed:
October 25, 2023
Publication date:
March 14, 2024
Applicants:
Saudi Arabian Oil Company, King Abdullah University of Science and Technology
Inventors:
Robert Peter Hodgkins, Omer Refa Koseoglu, Kuo-Wei Huang, Jean-Marie Maurice Basset, Yu Han, Rajesh Parsapur, Anissa Bendjeriou Sedjerari, Sathiyamoorthy Murugesan
Abstract: Provided are photoacoustic imaging contrast agents that include at least one radiation-absorbing component comprising a copper-complexed and/or manganese-complexed chlorin and/or bacteriochlorin and/or a derivative thereof, or a combination thereof. Also provided are methods for using the disclosed photoacoustic imaging contrast agents either singly or in combination for generating an image of a volume, optionally a subject or a body part, cell, tissue, or organ thereof. Further provided are compositions and methods for multiplex photoacoustic imaging of a volume, optionally a subject or a body part, cell, tissue, or organ thereof using photoacoustic imaging contrast agents that include a plurality of the presently disclosed copper-complexed and/or manganese-complexed chlorins and/or bacteriochlorins and/or derivatives thereof simultaneously.
Type:
Application
Filed:
January 4, 2022
Publication date:
March 14, 2024
Applicant:
NIRvana Sciences, Inc.
Inventors:
James Bruce Pitner, Russell D. Thomas, Joshua O. Akhigbe
Abstract: The present invention provides a compound represented by the following formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein: R1 and R2 are each separately selected from the group consisting of hydrogen, alkyl, alkenyl, acyl, and hydroxyalkyl; R3 is hydrogen or halogen; ring A is a benzene ring or a pyridine ring; ring B is selected from the group consisting of the following formulas (i), (ii), (iii), and (iv): in the formula (ii), Ra is alkyl; R4 and R5 are each separately selected from the group consisting of hydrogen, hydroxy, alkoxy, haloalkoxy, halohydroxyalkoxy, and aminoalkyl; and represents a double bond or a triple bond. The above compound can be used as a molecular probe for imaging tau proteins that accumulate in the brain.
Type:
Application
Filed:
May 8, 2023
Publication date:
March 14, 2024
Applicant:
National Institutes for Quantum and Radiological Science and Technology
Abstract: A method for determining tobacco-specific nitrosamines (TSNAs) in tobacco using one-step clean-up coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) is provided, including the following steps: destemming flue-cured tobacco or sun-cured tobacco, drying, milling, and passing through a sieve; mixing the resulting tobacco, an internal standards solution and water in a plastic centrifuge tube, and vortexing the resulting mixture at room temperature to allow extraction; transferring an extraction solution after filtration to a new centrifuge tube, adding dichloromethane, and vortexing the resulting mixture; centrifuging to collect a dichloromethane extraction solution in a lower layer to another centrifuge tube, and placing the centrifuge tube in a water bath to remove dichloromethane; dissolving the resulting extraction solution in water, and transferring the resulting solution to an autosampler vial for LC-MS/MS analysis.
Type:
Application
Filed:
November 17, 2023
Publication date:
March 14, 2024
Applicant:
Yunnan Academy Of Tobacco Agricultural Sciences
Inventors:
Yong LI, Tao PANG, Junli SHI, Zhongbang SONG, Ge BAI, He XIE, Xingxiang WU, Niannian HU, Suxing TUO, Yunhui DAI