Patents Assigned to Sciences
  • Patent number: 12302759
    Abstract: The present disclosure relates to a method for obtaining lead-free piezoelectric materials, including: Step S100, adjusting the T/O phase boundary of a first lead-free piezoelectric material: for the first lead-free piezoelectric material, adjusting the T/O phase boundary between the tetragonal phase T and the orthorhombic phase O to be near the room temperature by doping; Step S200, further adjusting the C/T phase boundary and the O/R phase boundary: further adjusting the C/T phase boundary between the cubic paraelectric phase C and the tetragonal phase T, and the O/R phase boundary between the orthorhombic phase O and the rhombohedral phase R by doping, so as to enable the C/T phase boundary and the O/R phase boundary to approach the T/O phase boundary; and Step S300, obtaining second lead-free piezoelectric materials: obtaining multiple second lead-free piezoelectric materials with different piezoelectric constants d33 and different Curie temperatures TC in the process.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: May 13, 2025
    Assignees: Xi'an Jiaotong University, National Institute for Materials Science
    Inventors: Xiaobing Ren, Shuai Ren, Yanshuang Hao, Minxia Fang
  • Patent number: 12295615
    Abstract: The present disclosure relates to laparoscopic surgery, and in particular to laparoscopic ports for facilitating the implant of medical systems such as a neuromodulation system into the body of a patient. Particularly, aspects are directed to a cannula assembly having a cannula housing and a cannula sleeve comprising a sleeve body extending from a distal end of the cannula housing. The cannula sleeve has a semi-rectangular cross section including: (i) a rounded rectangular portion configured to accommodate feeding the neuromodulation system through the cannula assembly, and (ii) a circular portion configured to accommodate insertion of the one or more surgical instruments through the cannula assembly.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: May 13, 2025
    Assignee: Verily Life Sciences LLC
    Inventors: Benjamin K. Yaffe, Shivkumar Sabesan, Eric Irwin
  • Patent number: 12297226
    Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
    Type: Grant
    Filed: January 11, 2024
    Date of Patent: May 13, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Elaine Bunyan, Byoung-Kwon Chun, Kassibla E. Dempah, Hon C Hui, Rao V. Kalla, Richard L. Mackman
  • Patent number: 12301015
    Abstract: The embodiments relate to a real-time approximation method and apparatus of a mutual inductance between transmitters and receivers for determining an optimal operating condition in a multiple-receiver wireless power transfer system, and it may be configured to approximate a mutual inductance in the multiple-receiver wireless power transfer system according to a configuration status of the receivers, and determine an operating condition of the multiple-receiver wireless power transfer system based on the mutual inductance. According to the various example embodiments, the inductance may comprise a mutual inductance between the transmitter and the receivers, and a mutual inductance between the receivers.
    Type: Grant
    Filed: May 24, 2022
    Date of Patent: May 13, 2025
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: In Gwun Jang, Mingi Kim, Minseok Kang
  • Patent number: 12295992
    Abstract: Disclosed is the use of ALDH1A and an agonist, a catalysate and an inhibitor thereof. In particular, disclosed is the use of ALDH1A or an agonist thereof, or a catalysate thereof in the preparation of a pharmaceutical composition or a formulation for the treatment and/or prevention of autism.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: May 13, 2025
    Assignee: Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences
    Inventors: Ronggui Hu, Xingxing Xu, Xiaobo Gao, Chuanyin Li, Zijian Hao
  • Patent number: 12297510
    Abstract: A method for detecting a methylated genomic locus is provided. In certain embodiments, the method comprises: a) treating a nucleic acid sample that contains both unmethylated and methylated copies of a genomic locus with an agent that modifies cytosine to uracil to produce a treated nucleic acid; b) amplifying a product from the treated nucleic acid using a first primer and a second primer, wherein the first primer hybridizes to a site in the locus that contain methylcytosines and the amplifying preferentially amplifies the methylated copies of the genomic locus, to produce an amplified sample; and c) detecting the presence of amplified methylated copies of the genomic locus in the amplified sample using a flap assay that employs an invasive oligonucleotide having a 3? terminal G or C nucleotide that corresponds to a site of methylation in the genomic locus.
    Type: Grant
    Filed: May 12, 2023
    Date of Patent: May 13, 2025
    Assignee: Exact Sciences Corporation
    Inventors: Graham P. Lidgard, Michael J. Domanico, Hatim Allawi, Hongzhi Zou
  • Patent number: 12299875
    Abstract: A computer-implemented method (530), system (100, 201) and computer readable medium for generating a slide-free histological image in the form of a reconstructed ultraviolet-based autofluorescence microscopy (UV-AutoM) image from a plurality of speckle-illuminated low-resolution images. A computer implemented method (1150), system (100, 201) and computer readable medium for generating a slide-free histological image in the form of a pseudo-hematoxylin and cosin (H&E) stained image (1120) from a grayscale input image such as a UV-AutoM image or a ultraviolet-based photoacoustic microscopy (UV-PAM) image (1110).
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: May 13, 2025
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Tsz Wai Wong, Yan Zhang, Lei Kang, Xiufeng Li, Hei Man Wong
  • Patent number: 12300251
    Abstract: The present invention relates to a speaker diarization technology, and more specifically to, end-to-end speaker diarization system and method through transformer learning having an auxiliary loss-based residual connection to separate speakers by dividing the speakers for time interval, wherein the end-to-end speaker diarization system and method using an auxiliary loss can differentiate and separate speakers through speaker labeling based on the transformer learning using an auxiliary loss even if speaker speeches overlap in a multi-speaker environment.
    Type: Grant
    Filed: November 29, 2022
    Date of Patent: May 13, 2025
    Assignee: Gwangju Institute of Science and Technology
    Inventors: Dong Keon Park, Hong Kook Kim, Ye Chan Yu
  • Patent number: 12296318
    Abstract: A COF@hydromagnesite composite material and its preparation method and application are disclosed. The preparation method of the composite material includes the following steps. Firstly, diisocyanate organic matters are used as a modifier to carry out chemical reaction with the hydromagnesite powder to obtain modified hydromagnesite powder particles. Secondly, tris(4-aminophenyl)amine and 2,5-dihydroxyterephthalaldehyde are adopted as reaction monomers for reacting to obtain the Covalent Organic Framework (COF) material. And finally, taking modified hydromagnesite powder particle as a core and COF as a shell, the COF@hydromagnesite composite material is prepared. The COF@hydromagnesite composite material synthesized by the method disclosed by the disclosure is simple in preparation process, high in stability and good in selectivity, which can be used for adsorption treatment of lead ions in water.
    Type: Grant
    Filed: December 26, 2024
    Date of Patent: May 13, 2025
    Assignee: Hunan Institute of Science and Technology
    Inventors: Yongbing Yuan, Hao Ma, Junkang Shi, Congshan Zhou, An Li, Lijun Li, Jundong Xu
  • Patent number: 12299976
    Abstract: Introduced here are health management platforms able to monitor changes in the health state of a subject based on the context of digital activities performed by, or involving, the subject. Initially, a health management platform can identify a physiological response by examining physiological data associated with a subject. Then, the health management platform can identify a stimulus presented by an electronic device that provoked the physiological response by examining contextual data associated with the subject. The contextual data may be in the form of a screenshot of a computer program in use by the subject during the physiological response. In some embodiments, the health management platform prompts the subject to specify whether the physiological response is a positive physiological response that resulted in an upward shift in health or a negative physiological response that resulted in a downward shift in health.
    Type: Grant
    Filed: January 30, 2023
    Date of Patent: May 13, 2025
    Assignee: Verily Life Sciences LLC
    Inventor: Erin Rainaldi
  • Patent number: 12298208
    Abstract: The present application disclose a device for preparing rock samples with different moisture contents, which comprises a sample container, wherein two ends of the rock sample are respectively connected with a first steam inlet and a first steam outlet of the sample container; the first steam outlet, a pump and a gas-liquid separator are connected in sequence, a gas outlet end of the gas-liquid separator, a steam compressor and the first steam inlet are connected in sequence, and a liquid outlet end of the gas-liquid separator, a steam generator and the steam compressor are connected in sequence. The water vapor in the sample container is pumped into the gas-liquid separator by the pump to separate low-temperature water vapor and condensate, and the low-temperature water vapor and condensate form high-temperature and high-pressure steam again and return to the inside of the sample container. The water in the steam generator always circulates inside the preparation device.
    Type: Grant
    Filed: May 22, 2024
    Date of Patent: May 13, 2025
    Assignee: Institute of Geology and Geophysics, Chinese Academy of Sciences
    Inventors: Hang Bian, Zhaobin Zhang, Shouding Li, Xiao Li, Jianming He, Bo Zheng, Tianqiao Mao, Guanfang Li, Peng Guo
  • Patent number: 12297101
    Abstract: Provided is a method of manufacturing a stretchable substrate according to various embodiments of the present disclosure in order to implement the above-described objects. The method may include forming an auxetic including a plurality of unit structures and forming one or more microstructures.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: May 13, 2025
    Assignee: Korea Institute of Science and Technology
    Inventors: Seungjun Chung, Phillip Lee, Jeong Gon Son, Heesuk Kim, Jai Kyeong Kim, Seunghyun Lee, Byeongmoon Lee
  • Patent number: 12298266
    Abstract: Systems and methods include a computer-implemented method for determining a concentration of hydrocarbon fuel in a fluid sample. A thin Cyclic Olefin Copolymer (COC) film of a COC layer having a honeycomb mesh-pattern forming a conductive metal trace is sputtered. The thin COC film is configured to dissolve upon contact with alkyl aromatic compounds present in hydrocarbon fuels. A fluid sample of a hydrocarbon fuel is positioned in an open area on the thin COC film. A resistivity of the conductive metal trace is monitored. A determination is made in response to the monitoring that a change in resistivity of the conductive metal trace has occurred resulting from dissolution of the thin COC film. A time duration is measured from the positioning of the fluid sample to the resistivity change. A concentration of the hydrocarbon fuel in the fluid sample is determined based on the time duration.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: May 13, 2025
    Assignees: Saudi Arabian Oil Company, King Abdullah University of Science and Technology
    Inventors: Maha Nour, Ayman Amer, Abdullah Hassan Bukhamsin, Esraa Fakeih, Sumana Bhattacharjee, Khaled Nabil Salama
  • Patent number: 12301086
    Abstract: A magnetic levitation rotor sail is proposed. The rotor sail may include a coil unit provided at a lower portion of a body of the rotor sail, and an electromagnet configured to levitate the coil unit. The rotor sail may also include a support member supporting the electromagnet, and a gap sensor provided at the support member and configured to measure a gap between the coil unit and the electromagnet.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: May 13, 2025
    Assignee: Korea Institute of Ocean Science & Technology
    Inventors: Hee Jin Kang, Yunho Kim
  • Patent number: 12299853
    Abstract: Systems and methods for de-smoking images of a surgical scene are described. Methods include receiving a video of a surgical scene including an image frame. Methods include determining that the image frame includes a smoke occlusion. Methods include determining an estimated un-occluded color of one or more pixels of the image frame using a lookup table, the lookup table mapping between a color space and a set of color bins including the estimated un-occluded color. Methods include determining a respective estimated true color for the one or more pixels of the subset using the imaged color, the estimated un-occluded color, and the smoke color. Methods also include generating a de-smoked image frame using the respective estimated true colors of the one or more pixels, the de-smoked image exhibiting a reduction of the smoke occlusion relative to the image frame.
    Type: Grant
    Filed: October 14, 2022
    Date of Patent: May 13, 2025
    Assignee: Verily Life Sciences LLC
    Inventors: Ravish Malhotra, Kirk Gossage
  • Patent number: 12297041
    Abstract: A diaper pail is disclosed. The diaper pail includes a scale configured to determine a weight of an absorbent article. The diaper pail further includes a light source positioned to transmit light at an excitation wavelength of a biological substance. The diaper pail further includes a photodetector positioned to detect a measurement of light intensity within the range of emission wavelengths of the biological substance. The diaper pail includes a processor that is configured to execute processor-executable instructions to receive the weight of the absorbent article and the measurement of light intensity and to detect a presence of the biological substance on the absorbent article.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: May 13, 2025
    Assignee: Verily Life Sciences LLC
    Inventor: Brian Schiffer
  • Patent number: 12297483
    Abstract: Provided are molecules and methods for detecting enzymatic activity of various lysosomal storage enzymes. The molecules may be used as internal standards that may be combined with substrates that have improved solubility.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: May 13, 2025
    Assignees: Revvity Health Sciences, Inc., University of Washington through its Center for Commercialization
    Inventors: Alexander Cherkassky, Jason Cournoyer, Michael Gelb
  • Patent number: 12301528
    Abstract: Methods, systems, and media for providing automated review of incoming messages in a group messaging service are provided.
    Type: Grant
    Filed: September 8, 2023
    Date of Patent: May 13, 2025
    Assignee: Integral Ad Science, Inc.
    Inventors: Vikram Gupta, Prashant Jawale, Bhavinkumar Jatinkumar Shah
  • Patent number: 12298366
    Abstract: Embodiments include methods (and related systems, devices, and apparatuses) for determining a sorption separation factor for a binary gas mixture by applying a magnetic field to at least a portion of a sorbent (604) disposed in a chamber of a magnetic susceptibility device; directing a first gas stream including a first gas compound into the chamber at a first pressure and temperature to obtain a first magnetic susceptibility measurement; directing a second gas stream including a second gas compound into the chamber at a second pressure and temperature to obtain a second magnetic susceptibility measurement; directing a binary gas mixture including the first gas compound and the second gas compound into the chamber at a third pressure and temperature to obtain a third magnetic susceptibility measurement; and determining a sorption separation factor based on the first, the second, and the third magnetic susceptibility measurements.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: May 13, 2025
    Assignee: Khalifa University of Science and Technology
    Inventors: Dionysios Karousos, Andreas Sapalidis, Georgios Karanikolos, Evangelos Favvas
  • Patent number: 12298469
    Abstract: Systems and methods which provide single nanostructure-integrated metalens configurations implementing projector and light shaper functionality are described. A single nanostructure-integrated metalens may comprise an optical substrate having a preconfigured mapping of integrated nanostructures providing metasurfaces for modulating the behaviors of electromagnetic waves to implement a thin, flat lens. A period distance for the nanostructures, a height of the nanostructures, and a quantization for lateral sizes of the nanostructures may be selected for a particular single nanostructure-integrated metalens configuration. A first phase map may be computed with respect to structured light generation and a second phase map may be computed with respect to light collimation, wherein fusion of these phase maps may be used to define a preconfigured mapping for the nanostructures of a single nanostructure-integrated metalens implementation.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: May 13, 2025
    Assignee: Hong Kong Applied Science and Technology Research Institute Co., Ltd.
    Inventors: Yunhe Lai, Haoyuan Bai, Qingyi Yang, Jinbo Jiang