Abstract: This invention relates to dihydropyranopynmidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.

Abstract: A new and distinct Cynara cardunculus var. scolymus L. cultivar of artichoke plant named ‘PS-MSG0677’, characterized by its fleshiness of bracts; fleshiness of hearts; uniformity of head shapes; and male sterility which is demonstrated by the absence of pollen on all florets during anthesis.

Abstract: One example device for overcurrent protection for wireless power receivers includes a wireless power antenna comprising a wire coil; a conditioning circuit electrically coupled to the wireless power antenna to receive an electric power signal from the wireless power antenna; a temperature-sensitive fuse electrically coupled between the wireless power antenna and the conditioning circuit and configured to electrically decouple the wireless power antenna from the conditioning circuit in response to being blown; and a thermal energy source configured to generate thermal energy based on an electrical signal from an output of the conditioning circuit, the thermal energy source positioned proximate the temperature-sensitive fuse.

Abstract: Embodiments of the technology relate to a contact lens having a core that is covalently coated by a hydrogel layer, and to methods of making such a lens. In one aspect, embodiments provide for a coated contact lens comprising a lens core comprising an outer surface; and a hydrogel layer covalently attached to at least a portion of the outer surface, the hydrogel layer adapted to contact an ophthalmic surface, wherein the hydrogel layer comprises a hydrophilic polymer population having a first PEG species and a second PEG species, the first PEG species being at least partially cross-linked to the second PEG species.

Abstract: Various embodiments may provide a circuit arrangement. The circuit arrangement may include a first spin-orbit torque magnetic tunnel junction cell, a second spin-orbit torque magnetic tunnel junction cell, a first driver circuit arrangement, a second driver circuit arrangement, and a read circuit arrangement. The circuit arrangement allows for the operation of a non-volatile flip-flop based on spin-orbit torque effect.

Abstract: A flexible intraocular lens including a flexible, transparent conductor disposed on a sidewall is disclosed herein. An example flexible intraocular lens includes an annular body and a transparent and flexible conductor. The annular body having at least one inner surface, where the annular body is formed from a flexible biocompatible material amenable to implantation into an eye. The transparent and flexible conductor formed on the at least one inner surface, the transparent and flexible conductor being one of a conductive polymer or a conductive nanowire-based mesh.

Abstract: An implant including a housing having a peripheral frame including an inner edge defining central opening in a central portion of the implant. The implant may also include a blade located within the central opening, the blade having a retracted position in the housing and an extended position where the blade extends outwardly from the housing. In addition, the implant may include a blade actuating component comprising a driven shaft portion and a blade engaging portion. The blade actuating component may be configured to be translated to move the blade between the retracted position and the extended position. Also, the inner edge of the peripheral frame may include a posterior edge configured to support the blade in two locations.

Abstract: The present invention relates to a glass having a surface with improved water-repellency or hydrophobicity and low reflectance, and a fabrication method thereof. A technology is employed, in which a thin film containing silicon or silicon oxide is formed on the glass surface, the nano-structures are formed by selective etching treatment using a reactive gas such as CF4 or the like to provide superhydrophobicity and low reflectance properties, and a material with low surface energy is coated onto the nano-structures. The fabrication method of the low-reflective and superhydrophobic or super water-repellent glass may execute deposition and etching processes for the glass having the superhydrophobicity and the low reflectance, and provide excellent superhydrophobicity and low reflectance to the surface of the glass which was difficult to be treated. Also, the method is sustainable due to non-use of a toxic etching solution during these processes.

Abstract: Provided are a platelet-derived growth factor B derivative, the encoding nucleic acid molecule thereof, and a vector and host cell having the nucleic acid molecule. Also provided are a preparation method for the mutant, and the use of the mutant in preparing medications for promoting cell division, cell proliferation, wound healing, skin regeneration, bone and tooth defect regeneration, and joint repair.

Abstract: A muon detector system capable of determining muon direction and flight trajectory or path is disclosed. The muon detector system includes scintillators for determining muon direction, and an array of muon detectors arranged in orthogonal layers for determining flight trajectory. The system can be used for tomographic and telescopic mode imaging, and may be used for imaging concealed and/or subterranean objects.

Abstract: A multi-standard transmitter architecture with digitally upconverted intermediate frequency (IF) outphased signals is disclosed. The transmitter architecture includes a Gallium Nitride (GaN) power amplifier (PA) circuit having a Current Mode Class-D (CMCD) configuration. The GaN PA circuit includes a lower switching device electrically coupled to an input to receive an input RF signal and an upper switching device to switchably electrically couple the first switching device to a power supply to drive an antenna circuit based on the input RF signal. Thus, a reconfigurable transmitter architecture is disclosed that utilizes a high-speed Gallium Nitride (GaN) driver to achieve a peak drain efficiency of at least 85% while delivering output power of 10 W at 1 GHz frequency, for example.

Abstract: An electronic circuit includes a reference ADC, a delay circuit, and a main ADC. The reference ADC converts an input signal to an upper bit string of output data, in response to a reference clock. The delay circuit delays a source clock by a delay time to output a main clock. The main ADC converts the input signal to a lower bit string of the output data, in response to the main clock. When a value of the most significant bit included in the lower bit string is identical to a value of the bit which is adjacent to the most significant bit and lower than the most significant bit, the delay time is adjusted based on a direction in which a level of the input signal is changed and the value of the most significant bit of the lower bit string.

Abstract: Disclosed herein are systems and methods for specifying treatment criteria and treatment planning parameters for patient specific radiation therapy planning. According to an aspect, a method includes receiving data about a patient, computing geometric characterization of one or more organs at risk proximate to a target volume of a patient or vice versa, and selecting relevant treatment knowledge and experience. The method also includes generating, based on the received data, computed geometric characterization, and available knowledge and experience, a first set of radiation treatment planning parameters that will lead to a high quality plan for the patient. Further, the method includes model-based prediction, based on the data, a second set or more of radiation treatment planning parameters that will lead to alternative achievable plans with different organ sparing objectives for treating the patient. The multiple sets for parameters can be used separately or in conjunction to generate treatment plans.

Abstract: Inhibitors of HBV replication of Formula (IA) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X and R1 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.

Abstract: The invention provides a solid state dye laser and methods for preparing the solid state dye laser. The solid state dye laser includes a porous copolymer membrane of poly(vinylidenefloride-cohexafluoroproplyne (PVDF-HFP) and a laser dye. The laser dye is incorporated in pores of the copolymer membrane. The solid state dye laser is prepared using one of a phase inversion technique, a phase separation technique, and a breath figure technique.

Abstract: Provided are methods and compositions for cartilage repair. The method involves performing a surgical procedure at the site of a cartilage defect and administering a composition comprising a receptor for hyaluronan mediated motility (RHAMM)-mimetic peptide, and a high molecular weight hyaluronan.

Abstract: Apparatuses and methods for an interposer for integration of multiple image sensors are disclosed herein. An example apparatus includes an interposer including laterally spaced first and second windows, and first and second image sensors disposed on the interposer over the first and second windows, respectively. The interposer including conductive conduits formed in or on to provide electrically conductive paths there through with the first and second image sensors coupled to the conductive conduits. The first and second image sensors laterally spaced by a gap, and an active area of the first and second image sensors to receive incident light through the respective first and second windows, where a perspective of the first image is different than a perspective of the second image sensor based at least in part on the gap.

Abstract: There is provided a microfluidic device comprising: a plurality of wells, each well having an inlet and an outlet, wherein the inlets are in fluid communication with one or more entry channels and the outlets are in fluid communication with one or more exit channels, wherein said outlet is connected to the exit channel via an outlet connecting channel and said inlet is connected to the entry channel via an inlet connecting channel wherein the dimension of the outlet connecting channel is configured such that the surface tension of a liquid comprised in the well prevents the release of the liquid through the outlet connecting channel. There is also provided a system, method and use of the device.

Abstract: The present invention relates to composite hydrogels comprising at least one non-peptidic polymer and at least one peptide having the general formula: Z—(X)m—(Y)n—Z?p, wherein Z is an N-terminal protecting group; X is, at each occurrence, independently selected from an aliphatic amino acid, an aliphatic amino acid derivative and a glycine; Y is, at each occurrence, independently selected from a polar amino acid and a polar amino acid derivative; Z? is a C-terminal protecting group; m is an integer selected from 2 to 6; n is selected from 1 or 2; and p is selected from 0 or 1. The present invention further relates to methods of producing the composite hydrogels, to uses of the composite hydrogels for the delivery of drugs and other bioactive agents/moieties, as an implant or injectable agent that facilitates tissue regeneration, and as a topical agent for wound healing.

Abstract: A Quadrature-In, Quadrature-Out (QIQO) clock divider divides by an odd divisor, such as three. An IQ input clock has in-phase and quadrature differential signals. Four stages of dynamic logic are arranged into a loop, with each stage output being one of four IQ output signals that have 90-degree phase separations. Each stage output drives the gates of a p-channel charging transistor and an n-channel discharging transistor of a next stage. Two p-channel charging logic transistors are in series between the next stage output and the p-channel charging transistor, and two n-channel evaluation transistors are in series between the next stage output and the n-channel discharging transistor. Different pairs of the four IQ input clock signals are applied to their gates. When the prior stage output is low, the stage output is charged. When the prior stage output is high, the stage output discharge timing is determined by the IQ signals.