Patents Assigned to Sciences
  • Patent number: 10431341
    Abstract: The invention provides a detection device, method, and program capable of highly accurately detecting a pre-disease state that indicates a precursor to a state transition from a healthy state to a disease state. The following processes are carried out: a process of obtaining measured data on genes, proteins, etc. related to a biological object as high-throughput data (s1), a process of selecting differential biological molecules (s2), a process of calculating the SNE of a local network (s3), a process of selecting a biomarker candidate (s4), a process of calculating an average SNE across the entire network (s5), and a process of determining and detecting whether or not the system is in a pre-disease state (s6).
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: October 1, 2019
    Assignee: Japan Science and Technology Agency
    Inventors: Kazuyuki Aihara, Luonan Chen, Rui Liu
  • Patent number: 10428062
    Abstract: The present invention relates to novel geminal substituted aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of ?7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: October 1, 2019
    Assignee: Axovant Sciences GmbH
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • Patent number: 10432311
    Abstract: This invention relates to methods and systems for optimizing network catchment areas, in particular based on completion times of the customer premises. Embodiments of the invention aggregate different customer premises to form demarcated catchment areas by minimizing the overall weighted cost function comprising the distance and completion time within each catchment area, while also considering practical constraints. Embodiments of the invention allow network planners to specify their preferences of distance against time to produce cost-effective network schemes for very large numbers of customer premises and form network catchment areas without any overlapping.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: October 1, 2019
    Assignees: Khalifa University of Science and Technology, British Telecommunications PLC, Emirates Telecommunications Corporation
    Inventors: Kin Fai Poon, Fabrice Saffre, Kaltham Saeed Khalfan Alromaithi, Anis Ouali, Beum Seuk Lee
  • Patent number: 10432144
    Abstract: A high-frequency phase-locked oscillation circuit having an extremely narrow peak width and a stable frequency so that a high-frequency wave that is oscillated by the MR element solves a problem of a large peak width of oscillation spectrum. The high-frequency phase-locked oscillation circuit includes a magnetoresistive element that oscillates a high-frequency wave with an oscillating frequency; a reference signal source that outputs a reference signal with a reference frequency; a phase-locked loop circuit having a phase comparator, a loop filter, and a frequency divider; an adder that adds a phase error signal output from the loop filter and a bias voltage for oscillating the high-frequency wave from the magnetoresistive element, and that inputs an added bias voltage to the magnetoresistive element; and a filter provided between the frequency divider and the magnetoresistive element.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: October 1, 2019
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Shingo Tamaru, Hitoshi Kubota, Akio Fukushima, Shinji Yuasa
  • Patent number: 10426642
    Abstract: A membrane for covering a peripheral surface of a stent is provided, the membrane including a plurality of line openings formed therein. Each line opening may be a straight line opening, for example in the form of a slit, a curved line opening, or any line opening of a suitable shape or curvature, e.g. U-shaped or V-shaped. Blood pressure opens the slits to allow blood to flow through the membrane, while curved line openings create a flap in the membrane that can open to allow blood to pass through. According to further embodiments of the present invention, a method of forming a membrane on a stent and a device for use in a blood vessel are provided.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: October 1, 2019
    Assignees: National University of Singapore, Agency for Science, Technology and Research
    Inventors: Pei Ho, Hwa Liang Leo, Sum Huan Ng, Fangsen Cui, Foad Kabinejadian
  • Patent number: 10426363
    Abstract: A magnetoencephalography (MEG) measuring apparatus and an MEG measuring method. The MEG measuring apparatus includes a superconducting helmet having an inward brim, a sensor-equipped helmet disposed inside the superconducting helmet, a pick-up coil disposed inside the sensor-equipped helmet, and a superconducting quantum interference device (SQUID) sensor mounted on the sensor-equipped helmet and connected to the pick-up coil.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: October 1, 2019
    Assignee: Korea Research Institute of Standards and Science
    Inventors: Kwon-Kyu Yu, Yong-Ho Lee, Kiwoong Kim, Jin-Mok Kim, Hyukchan Kwon, Sang-Kil Lee
  • Patent number: 10426605
    Abstract: A mitral valve replacement device is adapted to be deployed at a mitral valve position in a human heart. The device has an atrial flange defining an atrial end of the device, a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm, and an annulus support that is positioned between the atrial flange and the ventricular portion. The annulus support includes a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors. A plurality of leaflet holders positioned at the atrial end of the atrial flange, and a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange at a location above the native annulus.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: October 1, 2019
    Assignee: Sino Medical Sciences Technology, Inc.
    Inventors: Jianlu Ma, Yong Huo, Tianzhu Li, Jinhong Zhao, Jianxiang Ma, Lei Meng
  • Patent number: 10427784
    Abstract: A system and method enabled to increase efficiency during a VTOL aircraft's transition. A VTOL aircraft enabled to operate multiple lift fans arranged into separately controllable groups, wherein the VTOL aircraft initially has vertical flight but transitions to horizontal flight. A first group of lift fans may be kept at full throttle, a second group of lift fans may be throttled to balance thrust and/or weight, and a third group of lift fans may be shut off.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: October 1, 2019
    Assignee: Aurora Flight Sciences Corporation
    Inventor: Robert Parks
  • Patent number: 10431901
    Abstract: A surface scattering antenna with a tightly-coupled or tightly-connected array of radiators provides an adjustable antenna with broadband instantaneous bandwidth.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: October 1, 2019
    Assignee: The Invention Science Fund, LLC
    Inventors: Eric J. Black, Brian Mark Deutsch, Alexander Remley Katko, Melroy Machado, Jay Howard McCandless, Yaroslav A. Urzhumov
  • Patent number: 10426393
    Abstract: Pilot health monitoring systems, methods, and apparatuses are provided. A pilot health monitoring system is configured to collect information regarding the pilot's physiological and/or physical characteristics, and information regarding a state of the aircraft; analyze the information; determine a health condition of the pilot and/or a state of the aircraft; and/or provide warnings and/or commands as a function of the information.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: October 1, 2019
    Assignee: Aurora Flight Sciences Corporation
    Inventors: William Robert Bosworth, Zarrin Khiang-Huey Chua, Jessica Edmonds Duda, Eugene H. Nahm
  • Patent number: 10427045
    Abstract: A multi-view display quest system includes a multi-view (MV) display including one or more MV pixels, wherein each MV pixel is configured to emit beamlets in different directions in a beamlet coordinate system; an input node configured to receive a first attribute of a first quest player or of a first viewing zone and, optionally, a second attribute of a second quest player or of a second viewing zone; and a system controller.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: October 1, 2019
    Assignee: Misapplied Sciences, Inc.
    Inventors: David Steven Thompson, Albert Han Ng, Paul Henry Dietz
  • Patent number: 10433027
    Abstract: Disclosed is a method and apparatus for IP-based hybrid 3DTV content transmission and reception. According to one aspect of the present disclosure, an IP-based hybrid 3DTV content reception apparatus includes: a receiving unit receiving multiplexed 3DTV content information; an additional data obtaining unit obtaining service layer signaling information from the received 3DTV content information, and obtaining additional data based on the obtained service layer signaling information; a decoding unit decoding the received 3DTV content information by using the obtained additional data; and a playing back unit playing back the decoded 3DTV content.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: October 1, 2019
    Assignees: Electronics and Telecommunications Research Institute, Foundation for Research and Business, Seoul National University of Science and Technology
    Inventors: Sung Hoon Kim, Hui Yong Kim, Jin Soo Choi, Dong Ho Kim, Dong Ho You, Jung Yup Jang
  • Publication number: 20190296760
    Abstract: An analog-to-digital converter (ADC) is provided. The ADC comprises an input terminal configured to receive input signals, a digital-to-analog converter (DAC), a first switch configured to control a connection between the DAC and the input terminal, a comparator, a second switch configured to control a connection between the DAC and the comparator, and a controller configured to control the first switch, the second switch, the DAC and the comparator.
    Type: Application
    Filed: March 13, 2019
    Publication date: September 26, 2019
    Applicants: SAMSUNG ELECTRONICS CO., LTD., Korea Advanced Institute of Science and Technology
    Inventors: JongPal KIM, Ye Dam KIM, Seung Tak RYU, Min Jae SEO, Dong Hwan JIN
  • Publication number: 20190295168
    Abstract: A method and a system for strategy-based digital asset trading are disclosed. The method includes: 1) generating an ownership identifier for a digital asset; 2) setting, in a transaction server, a transaction strategy for a digital asset owner associated with each ownership identifier; and 3) performing, by the transaction server, transaction matching and pricing according to a transaction strategy of a digital asset purchaser and the transaction strategy set for the ownership identifier. The method removes a bottleneck of human dealmaking in digital asset transactions, by performing direct matching of a supplier and a buyer of a fragmented transaction, thereby solving a low-efficiency problem in digital asset transactions in the Internet era.
    Type: Application
    Filed: March 23, 2017
    Publication date: September 26, 2019
    Applicant: Suzhou Superblock Chain Information Science & Technology Co., Ltd.
    Inventors: Xingguo SHI, Guangyu CHEN
  • Publication number: 20190292545
    Abstract: Disclosed herein are synthetic oligoribonucleotides that form hairpin loop structures. The oligoribonucleotides can be used in the treatment of viral infection including prophylactic treatments. The oligoribonucleotides can also be used as adjuvants.
    Type: Application
    Filed: December 12, 2018
    Publication date: September 26, 2019
    Applicant: Oregon Health & Science University
    Inventor: John Hiscott
  • Publication number: 20190292343
    Abstract: A method of preparation of a cardo polyetherketone structural foam material, including the following steps: 1) performing a mould pressing on a cardo polyetherketone resin by a high-temperature vulcanizing machine to prepare a foaming billet; 2) placing the foaming billet in a foaming cavity of a mould-pressing machine, performing a penetration and a swelling by introducing a supercritical fluid to achieve diffusion equilibrium, forming a polymer-supercritical fluid homogeneous solution, and 3) making the polymer-supercritical fluid homogeneous solution supersaturated through a sudden release of the inner pressure of the system, thereby inducing nucleation and foaming, and finally forming a structural foam having a closed pore structure with a uniform pore size and an adjustable pore density. The production process of the present invention is clean, environmentally friendly, and has relatively high efficiency. The obtained structural foam has good mechanical properties.
    Type: Application
    Filed: December 2, 2016
    Publication date: September 26, 2019
    Applicants: Changzhou Tiansheng New Materials Research Institute Co., Ltd., Chang Chun Institute of Applied Chemistry Chinese Academy of Sciences
    Inventors: Guangyuan ZHOU, Honghua WANG, Wei LI
  • Publication number: 20190291141
    Abstract: An LIBS-type object sorting device includes a three-dimensional-shape measurement means that acquires a space-coordinate group of a top face of an object to be sorted in top view on a conveyor, an LIBS analyzing means that performs chemical composition analysis on the object to be sorted while irradiating the object to be sorted with laser light, and a conveying-path switching means that switches a conveying path of the object to be sorted, in this order. The device includes a computing means that determines an analyzing section on which the LIBS analysis is to be performed, and a control means that causes a beam position to move and causes, when detecting that the analyzing section has reached from a movement amount of the conveyor, based on the movement amount, a beam-focus position to move along the analyzing section while irradiating the laser light.
    Type: Application
    Filed: July 4, 2017
    Publication date: September 26, 2019
    Applicant: National Institute of Advanced Industrial Science and Technology
    Inventors: Shigeki Koyanaka, Kenichirou Kobayashi
  • Publication number: 20190292519
    Abstract: Methods are provided of generating functional human oocytes following nuclear transfer of first polar body (PB1) genomes from metaphase II (MII) oocytes into enucleated donor MII cytoplasm (PBNT) and using mitochondrial replacement techniques to circumvent mother-to-child mtDNA disease transmission.
    Type: Application
    Filed: November 8, 2017
    Publication date: September 26, 2019
    Applicant: Oregon Health & Science University
    Inventors: Shoukhrat Mitalipov, Nuria Marti-Gutierrez, Dmitry Temiakov
  • Publication number: 20190292137
    Abstract: Disclosed are a compound represented by Formula I or a pharmaceutically acceptable salt thereof, a preparation method therefor, the Formula I, and an application thereof in preparing drugs for regulating blood lipids.
    Type: Application
    Filed: March 15, 2018
    Publication date: September 26, 2019
    Applicant: Shanghai Bioenergy Medicine Science & Technology Co., Ltd.
    Inventors: Yuqiong DONG, Quanhai LIU, Yu SHEN, Wentao CAI
  • Patent number: D861670
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: October 1, 2019
    Assignee: Chunzhixiao (Shenzhen) Science & Technology Co., Ltd.
    Inventor: Enmin Li