Patents Assigned to Sciences
  • Patent number: 10335757
    Abstract: A process for making a reduced size oxidant particle is provided. The process forms reduced sized oxidant particles by feeding a coating material and oxidant particles of an initial size into a mill. The coating material may be oleophilic, hydrophobic, siliphilic, hydrocarbon soluble, or a combination thereof. The oxidant particles are then milled, reducing the particle size of the oxidant particles. During the milling step, the coating coats a substantial portion of each reduced sized oxidant particle reducing reagglomeration during the milling step. Optionally, the oxidant particles produced by the process of the instant invention are encapsulated. Alternatively or additionally, the oxidant particles may be placed in suspension. An outermost encapsulant may be substantially non-reacting, impermeable and non-dissolving with water. The oxidant particles formed by the process of the present invention may be placed directly into or in the path of the contaminant(s) in the environmental media to be treated.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: July 2, 2019
    Assignee: Specialty Earth Sciences
    Inventors: Jason Swearingen, Lindsay Swearingen
  • Patent number: 10335048
    Abstract: Provided herein are methods and apparatuses for determining a level of cellular metabolic activity for a region of interest in order to detect and map on-going gliovascular unit metabolic activity using high-resolution 1H2O MRI. In one example approach, a computer-implemented method includes receiving a first set of DCE-MRI time-course data for a region, wherein a contrast agent is administered prior to imaging, identifying a region of interest from the first set of DCE-MRI time-course data for further analysis, performing shutter-speed pharmacokinetic analysis of the time-course data associated with the region of interest using computer-implemented software to obtain a finite and non-zero mean water molecule capillary lifetime in the region of interest, and indicating a level of cellular metabolic activity in the brain based on the mean water molecule capillary lifetime.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: July 2, 2019
    Assignee: Oregon Health & Science University
    Inventors: William Rooney, Charles Springer, Jr., Xin Li
  • Patent number: 10340551
    Abstract: A rocking-chair nonaqueous secondary battery, which uses an ion other than monatomic ions as a charge carrier, and in which the ion moves in and out of both the positive electrode and the negative electrode, can be provided by using a nonaqueous secondary battery electrolyte comprising a salt containing a charge carrier comprising a molecular ion. The nonaqueous secondary battery further comprises a positive electrode containing a positive electrode active material, and a negative electrode containing a negative electrode active material, wherein the positive electrode active material and the negative electrode active material are both materials that allow doping and dedoping of molecular anions (e.g., conductive polymers, organic radical polymers, polymers having a ferrocene skeleton, conductive carbon materials, or organic sulfur compounds), or the positive electrode active material and the negative electrode active material are both materials that allow doping and dedoping of molecular cations (e.g.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: July 2, 2019
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Masaru Yao, Hikaru Sano, Hisanori Ando, Tetsu Kiyobayashi
  • Patent number: 10340578
    Abstract: An electron-nuclear double resonance resonator, having a loop-gap resonator and an elongated lead; the loop-gap resonator comprises a plurality of arc-shaped conductive plates, and the elongated lead connects the arc-shaped conductive plates into a radio-frequency coil; the loop-gap resonator resonates at an electron resonance frequency, and the radio-frequency coil resonates at a nuclear resonance frequency; with the structure of the loop-gap resonator, the separation between an electric field and a magnetic field can be accelerated to ensure the maximization of the ratio of the magnetic field to the electric field inside a resonant resonator; and with the elongated lead, the impact of the lead to a resonance frequency and the mode of the loop-gap resonator is prevented as much as possible, and meanwhile the conductive plates of the loop-gap resonator can be connected into the radio-frequency coil.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: July 2, 2019
    Assignee: Wuhan Institute of Physics And Mathematics, Chinese Academy of Sciences
    Inventors: Chaoyang Liu, Quan Tao, Yugui He
  • Patent number: 10338078
    Abstract: The present invention provides an apparatus having a sample separation unit, a Raman spectroscopy unit, and a mass spectrometry unit. The present invention further provides a method for specifying a biomolecule and a method for identifying the binding site of the biomolecule and the low-molecular-weight compound, comprising a combination of Raman spectroscopy and mass spectrometry. The present invention further provides a surface-enhanced Raman spectroscopy method with improved sensitivity.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: July 2, 2019
    Assignee: Japan Science and Technology Agency
    Inventors: Mikiko Sodeoka, Jun Ando, Miwako Asanuma, Kosuke Dodo, Katsumasa Fujita
  • Patent number: 10334853
    Abstract: Compositions suitable for topical use to treat ectoparasite infestations are described. The compositions are suitable for use on the hair of humans or animals, without the need for pharmaceuticals or medicaments. The compositions are essentially nonaqueous and non-Newtonian, such that the compositions can be controllably delivered either manually or through use of a dispensing means. One such exemplary dispenser/applicator is described. Although the compositions are otherwise substantially free of water, they exhibit good risibility characteristics and pseudoplastic rheology. Methods for the use of the nonaqueous compositions and kits containing the compositions are also presented.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: July 2, 2019
    Assignee: Larada Sciences
    Inventors: Gregory van Buskirk, Kelly J. Brodbeck
  • Patent number: 10340831
    Abstract: A vibration suppression method and device of a wind power generator is provided. The method includes: calculating a specified value of a flux-weakening control parameter of the generator according to a preset value of an electromagnetic active power of the generator and a frequency of the generator; and controlling the generator according to the specified value of the flux-weakening control parameter of the generator. The method and device reduce the magnetic load of the generator by the flux-weakening control, thereby suppress vibration and noise of the generator.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: July 2, 2019
    Assignee: Beijing Goldwind Science & Creation Windpower Equipment Co., Ltd.
    Inventors: Yong Liu, Xiaohe Zhang, Xiang Zhao
  • Patent number: 10335417
    Abstract: The invention belongs to the technical field of medicines. In particular, the invention relates to a thiazideamide derivative compound or a pharmaceutically acceptable salt or solvate thereof, a pharmaceutical composition comprising the compound or a pharmaceutically acceptable salt or solvate thereof, a method for preparing the compound or a pharmaceutically acceptable salt or solvate thereof, and a use of the compound or a pharmaceutically acceptable salt or solvate thereof. For example, the compound or a pharmaceutically acceptable salt or solvate thereof according to the invention can be used to prevent and/or treat a neurodegenerative disease or a neuropathic disease caused by a physical trauma or a related disease.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: July 2, 2019
    Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
    Inventors: Song Li, Junhai Xiao, Boqun Lyu, Hongqiang Wang, Wu Zhong, Lili Wang, Zhibing Zheng, Yunde Xie, Xinbo Zhou, Xingzhou Li, Xiaokui Wang
  • Patent number: 10339224
    Abstract: A terminal equipment comprising: a voice input unit to accept an input of a voice; a speech recognition command unit to command a speech recognition unit to convert voices of joined voice data acquired by the voice input unit joining the voice data of the voice to the voice data of the voice accepted previously into character information of a first language at an interval; a character transmission unit to transmit first character information of the first language toward another terminal equipment whenever receiving the first character information of the first language converted; a translation command unit to command a translation unit to translate second character information of a second language into the first language whenever receiving the second character information of the second language; and a display unit to display the second character information of the first language together with the second character information of the second language.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: July 2, 2019
    Assignee: Fujitsu Social Science Laboratory Limited
    Inventor: Toshikazu Fukuoka
  • Patent number: 10339472
    Abstract: Systems and methods include: collecting digital threat scores of an incumbent digital threat machine learning model; identifying incumbent and successor digital threat score distributions; identifying quantiles data of the incumbent digital threat score distribution; collecting digital threat scores of a successor digital threat machine learning model; calibrating the digital threat scores of the successor digital threat score distribution based on the quantiles data of the incumbent digital threat score distribution and the incumbent digital threat score distribution; and in response to remapping the digital threat scores of the successor digital threat score distribution, publishing the successor digital scores in lieu of the incumbent digital threat scores based on requests for digital threat scores.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: July 2, 2019
    Assignee: Sift Science, Inc.
    Inventors: Fred Sadaghiani, Aaron Beppu, Jacob Burnim, Alex Paino
  • Patent number: 10335133
    Abstract: A positioning device is configured to selectively position or otherwise manipulate one or more organs within the body of a subject. The positioning device includes a shaped expandable element that is configured to be selectively transitioned between an unexpanded, or collapsed, state and an expanded state. While in the expanded state, the expandable element repositions or otherwise manipulates an organ. Systems that include positioning devices are also disclosed, as are methods for positioning or otherwise manipulating organs.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: July 2, 2019
    Assignee: Manual Surgical Sciences L.L.C.
    Inventor: Shawn P. Fojtik
  • Patent number: 10337498
    Abstract: A method and device for detecting equivalent load of wind turbine are provided. The method includes: detecting environment data of each wind turbine of multiple wind turbines in wind farm in each detection period; and in each detection period, detecting load of one or more calibration wind turbines in the multiple wind turbines, calculating equivalent load of the calibration wind turbines based on detected load, and determining equivalent load of each wind turbine based on detected environment data of each wind turbine with load estimation model, where load estimation model represents relation between environment data and equivalent load of wind turbine, and before load estimation model is applied in each detection period, parameter of load estimation model is calibrated based on the equivalent load calculated in current detection period and the equivalent load of the calibration wind turbines determined with load estimation model in previous detection period.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: July 2, 2019
    Assignee: Beijing Goldwind Science & Creation Windpower Equipment Co., Ltd.
    Inventors: Minghui Wang, Bo Juul Pedersen, Jian Li
  • Patent number: 10341374
    Abstract: Systems and methods include implementing a remote machine learning service that collects digital event data; collecting incumbent digital threat scores generated by an incumbent machine learning model and successor digital threat scores generated by a successor digital threat machine learning (ML) model; implementing anomalous-shift-detection that detects whether the successor digital threat scores of the successor digital threat ML model produces an anomalous shift; if the anomalous shift is detected by the machine learning model validation system, blocking a deployment of the successor digital threat model to a live ensemble of digital threat scoring models; or if the anomalous shift is not detected by the machine learning model validation system, deploying the successor digital threat ML model by replacing the incumbent digital threat ML model in a live ensemble of digital threat scoring models with the successor digital threat ML model.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: July 2, 2019
    Assignee: Sift Science, Inc.
    Inventors: Fred Sadaghiani, Keren Gu, Vera Dadok, Alex Paino, Jacob Burnim
  • Publication number: 20190196999
    Abstract: An FPGA-based square-wave generator and a square-wave generation method.
    Type: Application
    Filed: January 18, 2016
    Publication date: June 27, 2019
    Applicant: University of Science and Technology of China
    Inventors: Xi QIN, Yijin XIE, Xing RONG, Yu HE, Lin WANG, Zhifu SHI, Jiangfeng DU
  • Publication number: 20190194185
    Abstract: The present invention relates to phenyl [a]indole[2,3-g]quinolizine compounds represented by formula (I), a preparation method therefor, a pharmaceutical composition, and applications thereof. Specific applications are applications in the preparation of drugs for treating diseases related to a proprotein convertase subtilisin Kexin-9 (PCSK9), comprising the applications in the preparation of drugs for treating hyperlipemia, hypercholesterolemia, hypertriglyceridemia, fatty liver deformation, atherosclerosis, obesity and other metabolic diseases.
    Type: Application
    Filed: March 29, 2017
    Publication date: June 27, 2019
    Applicant: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Hong Liu, Yiping Wang, Fei Zhao, Jing Zhao, Jiang Wang, Cong Xi, Chenglin Wu, Hao Shen, Xu Han, Hualiang Jiang, Kaixian Chen
  • Publication number: 20190196046
    Abstract: A WEM-based method for deep resource detection using sky waves refers to the technical field of deep resource detection. The proposed method of deep detection using sky waves improves the traditional “atmospheric-lithosphere” half-space propagation theory into a full-space “sky wave” theory of “ionosphere-atmosphere-rock layer”, that is, the influence of the ionosphere and the displacement current in the air are taken into consideration to obtain a new precise expression of “sky wave” response, which is suitable for full space, slow attenuation and long distance propagation. A receiving device for sky wave signal has been developed. Through theoretical model calculation and actual data measurement, it is known that it is possible to use the sky wave for detection within the scope of China's national territory to realize the high-precision electrical structural exploration within a depth of 10 kilometers and open a new era of artificial source electromagnetic detection.
    Type: Application
    Filed: December 22, 2017
    Publication date: June 27, 2019
    Applicant: Institute of Geology and Geophysics, Chinese Academy of Sciences
    Inventors: Qingyun DI, Guoqiang XUE, Ruo WANG, Zhiguo AN, Changmin FU, Da LEI, Xianjun ZHUO, Zhongxing WANG
  • Publication number: 20190194374
    Abstract: Oligomers of certain glyceride compounds are generally disclosed herein. In some embodiments, the glyceride compounds include natural oil glycerides, such as glycerides derived from natural oils, such as palm oil, soybean oil, canola oil, and the like. Compositions containing such glyceride oligomers are also disclosed herein. Processes for making such glyceride oligomers are also disclosed herein. In some embodiments, the processes for making such compounds include reacting a plurality of unsaturated glyceride compounds in the presence of a metathesis catalyst.
    Type: Application
    Filed: November 19, 2018
    Publication date: June 27, 2019
    Applicant: Elevance Renewable Sciences, Inc.
    Inventors: Steven A. Cohen, Thomas E. Snead
  • Publication number: 20190192701
    Abstract: Provided are a conjugate including an EGFR inhibitor that enables treatment and diagnosis of epidermal growth factor receptor (EGFR)-overexpressing tumors including resistant tumors, a method that enables drug delivery treatment and diagnosis of EGFR-overexpressing tumors using the conjugate, and a method of preparing the conjugate.
    Type: Application
    Filed: December 26, 2018
    Publication date: June 27, 2019
    Applicant: Korea Institute of Radiological & Medical Sciences
    Inventors: Tae Sup Lee, Ik Joon Choi, Joo Hyun Kang
  • Publication number: 20190192125
    Abstract: An anatomical sensing system-guided prostate procedure device that includes a housing having a proximal end and a distal end. The housing may be divided into a distal housing section, a mid housing section, and a proximal housing section, wherein the distal housing section is configured for insertion into the anus and retention in the rectum of a subject. The device further includes an instrument convergence point disposed between the proximal end and the distal end, the convergence point configured to allow an instrument pass though the instrument convergence point at a variable angle; and an instrument angle orienting system at the proximal end of the housing, the angle orienting system directing an orientation of the variable angle about the convergence point. Methods of the using an anatomical sensing system-guided prostate procedure device and system including the same.
    Type: Application
    Filed: September 1, 2017
    Publication date: June 27, 2019
    Applicant: Oregon Health & Science University
    Inventors: Fergus Coakley, Stevan Wittenbrock, Forrest Seitz, Christopher J. Jensen, Daniel R. Baker
  • Publication number: 20190192060
    Abstract: Disclosed are a method, device and system for determining total circulating blood volume (BV) using a minimally invasive technique.
    Type: Application
    Filed: December 27, 2018
    Publication date: June 27, 2019
    Applicant: Oregon Health & Science University
    Inventors: Theodore Hobbs, Ravikant Samatham, Steven L. Jacques