Patents Assigned to SCIENTIFIQUE (CNRS)
  • Patent number: 12249361
    Abstract: The present disclosure concerns a method for fabricating a magnetoresistive element comprising a magnetic tunnel junction including a tunnel barrier layer, a first ferromagnetic layer and a second ferromagnetic layer; a writing current layer; and an interconnect layer configured for supplying the writing current to the writing current layer. A gap is provided in the interconnect layer such that the latter comprises two discontinuous interconnect segments extending along a layer plane and connecting the writing current layer in series. The method comprises: depositing the interconnect layer, writing current layer, second ferromagnetic layer, tunnel barrier layer and first ferromagnetic layer; forming the gap in the interconnect layer; filling the gap with the gap material; and forming the pillar by performing a single etch step until the interconnect layer, acting as a stop layer, is reached.
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: March 11, 2025
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Sylvain Martin, Julien Louche, Marc Drouard
  • Patent number: 12247306
    Abstract: The present invention describes an electrochemical system (1) to electrochemically reduce carbon monoxide (CO) into liquid methanol and gaseous H2, comprising an electrochemical cell with an anodic compartment with an anode (2) with a current collector (2A), at least a catalyst to electrochemically oxidize H2O, and a cathodic compartment with a cathodic electrolyte solution comprising the solvent (3), and a cathodic supporting electrolyte, the solvent (3) being water at basic pH of between 10.5 and 13.5, the reagent CO; a cathode (4) which comprises, on a current collector (4A) which is electrochemically inert, at least a cobalt molecular catalyst (4B) to electrochemically reduce CO into liquid methanol and the gas H2, a power supply (5) providing the energy necessary to trigger the electrochemical reactions involving the reagent.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: March 11, 2025
    Assignees: UNIVERSITÉ PARIS CITÉ, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marc Robert, Etienne Boutin
  • Patent number: 12247131
    Abstract: The present invention concerns a process for preparing an aqueous gel ink with fixed color comprising the following steps: (i) preparing a gel-based matrix of aqueous ink; (ii) preparing an aqueous suspension of silver nanoparticles with a fixed color by mixing silver salts with: —water, —a mixture of at least an alkali metal or alkaline earth metal salt of citrate, —an oxidizing agent, preferably hydrogen peroxide H2O2, —and polyvinylpyrrolidone; (iii) adding under agitation the aqueous suspension of silver nanoparticles obtained in step (ii) to the gel-based matrix of aqueous ink obtained in step (i), to obtain an aqueous gel ink with fixed color with silver nanoparticles dispersed therein.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: March 11, 2025
    Assignees: SOCIETE BIC, UNIVERSITÉ DE HAUTE-ALSACE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Olivier Albenge, Romain Metillon, Karine Mougin, Feriel Ghellal, Arnaud Spangenberg
  • Patent number: 12247018
    Abstract: A compound of formula (Ic) wherein X2 represents a —CO—NRk— group, wherein Rk represents a hydrogen atom or a methyl group, a —NH—CO—NH— group, a —OCH2— group, a —CH(OH)— group, a —NH—CO— group, a —O— group, a —O—(CH2)s—O—, a —CO— group, a —SO2— group, a divalent 5-membered heteroaromatic ring comprising 1, 2, 3 or 4 heteroatoms, a —NH—SO2— or a —SO2—NH— group; Y2 represents a hydrogen atom, a halogen atom, a hydroxyl group, a (C1-C4)alkoxy group, a a group, a group, a morpholinyl group, optionally substituted by a (C1-C4)alkyl group, a piperazinyl group, a piperidinyl group, or a —CR1R2R3 group, or any of its pharmaceutically acceptable salt.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: March 11, 2025
    Assignees: ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, INSTITUT CURIE
    Inventors: Didier Scherrer, Jamal Tazi, Florence Mahuteau-Betzer, Romain Najman, Julien Santo, Cécile Apolit
  • Patent number: 12247785
    Abstract: A cold crucible having application in the field of making monocrystalline materials at high temperature. The cold crucible includes: a cold cage having sectors made of a good electrical conductor material and in which a charge is molten, and a cooling device with a heat-transfer fluid, configured so as to cool down, from inside, each segment of the cold cage. At least one sector of the cold crucible includes a housing and is removable, the housing being proper and intended to accommodate at least one so-called functionalising device of the cold crucible. Henceforth, it is possible to functionalise each sector independently of the others, by accommodating therein, a functionalising device configured, inter alia, so as to modify and/or analyse at least one property of the charge, in particular the molten charge, in the cold cage.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: March 11, 2025
    Assignees: INSTITUT POLYTECHNIQUE DE GRENOBLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPES
    Inventors: Kader Zaidat, Christian Garnier, Ghatfan Hasan
  • Patent number: 12249882
    Abstract: An electrical machine for use in an aircraft, including a rotor. The rotor includes a plurality of rotor poles, and a stator including a plurality of phases. Each respective phase occupies at least one elementary block and the at least one elementary block of each phase includes a set of conductors of the respective phase wound around a plurality of slots of the respective elementary block in a concentrated winding configuration. A mechanical shift angle between the respective concentrated windings of each pair of adjacent elementary blocks is greater than a rotor pole pitch. The rotor pole pitch is an angle between adjacent poles of the rotor.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: March 11, 2025
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SAFRAN ELECTRICAL & POWER, SAFRAN LANDING SYSTEMS
    Inventors: Nadhem Boubaker, Daniel Matt, Florent Nierlich
  • Patent number: 12249468
    Abstract: A radio frequency micro-electromechanical switch (RF MEMS switch) is described. Also described is a method of producing such an RF MEMS switch. The method can include depositing on a substrate a first sacrificial layer and producing a pattern. A first layer of metal is deposited on the first sacrificial layer and on the substrate. A pattern is produced to form a first RF line and a first MEMS membrane. A second sacrificial layer is deposited on the first RF line and a pattern is produced. A dielectric layer is deposited on the second sacrificial layer and then a pattern is produced to form a dome. The first and second sacrificial layers are removed through a dome opening. A second metal layer is deposited on the dome and on the substrate, and then a pattern is produced to plug the dome opening(s) and to form a second RF line.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: March 11, 2025
    Assignees: UNIVERSITE DE LIMOGES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, AIRMEMS
    Inventors: Romain Stefanini, Ling Yan Zhang, Pierre Blondy, Fabien Roubeau, Kevin Nadaud
  • Patent number: 12247075
    Abstract: It is disclosed anti-BTN3A activating antibody fragments that specifically bind to BTN3A and activate the cytolytic function of V?9/V?2 T cells. The disclosure more specifically relates to specific anti-BTN3A binding proteins comprising such activating antibody fragments and their use in the manufacturing of novel drugs for use in treating cancer disorders, in particular cancers susceptible to be treated with activated ?? T cells.
    Type: Grant
    Filed: December 26, 2019
    Date of Patent: March 11, 2025
    Assignees: IMCHECK THERAPEUTICS SAS, INSTITUT JEAN PAOLI & IRENE CALMETTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE D'AIX-MARSEILLE
    Inventors: Alemseged Truneh, Christine Pasero, René Hoet, Magali Colazet, Daniel Olive
  • Patent number: 12250473
    Abstract: A method and a system for imaging a dynamic scene, by time-spectrum mapping when a single chirped pulse probes the dynamic scene, storing temporal information at different wavelengths, spectral shearing, spatial encoding and reverse spectral shearing; spatiotemporal integration; and image reconstruction from a resulting captured snapshot, using a laser source configured to emit a linearly chirped laser probe pulse; an imaging unit; a shearing and reversing shearing unit; an encoder; a detector; and a computer; wherein the imaging unit is configured to record the linearly chirped laser probe pulse transmitted by the dynamic scene in a snapshot; the shearing and reversing shearing unit is configured to spectrally shears the linearly chirped laser pulses received from the imaging unit to the encoder, the detector records a compressed snapshot of a temporal information of the dynamic scene read out by the probe pulse; and the computer processes the snapshot and yields a(x,y,t) datacube of the dynamic scene.
    Type: Grant
    Filed: February 17, 2023
    Date of Patent: March 11, 2025
    Assignee: INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jinyang Liang, François Légaré, Jingdan Liu, Heide Ibrahim, Xianglei Liu, Yingming Lai
  • Publication number: 20250081706
    Abstract: The invention refers to an electronic component, in particular an organic electrochemical transistor (OECT) which comprises at least one gate electrode, a source electrode, a drain electrode, a channel and an electrolyte. The electrolyte is a solid electrolyte comprising a polymer, and the channel comprises an organic semiconductor as channel material. The electrolyte has a low water content and/or a low C1-C3-alcohol content as well as a low maximum halogen alkaline salt or alkaline earth or acetate salt content. The invention further refers to the use of this electronic component as a Schmitt-Trigger or a Muller-C-element or a flip-flop or a 1-bit memory. Further, the invention provides a method for forming such an electronic component.
    Type: Application
    Filed: August 28, 2024
    Publication date: March 6, 2025
    Applicants: TECHNISCHE UNIVERSITÄT DRESDEN, UNIVERSITÉ PARIS-SACLAY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Hans KLEEMANN, Jann KRAUSSE, Lukas BONGARTZ, Karl LEO, Laurie CALVET, Zonglong LI
  • Publication number: 20250075247
    Abstract: The present invention relates to a method for determining the methicillin-resistance properties of a Staphylococcus aureus strain present in a biological sample, the method comprising the following steps: •a) incubating the biological sample containing the Staphylococcus aureus strain for at least 15 minutes in the presence of an antibiotic from the class of beta-lactams selected from the following group: cefoxitin and 6-APA (6-aminopenicillanic acid); •b) isolating the bacteria present in the biological sample; •c) lysing the bacteria and hydrolysing the bacterial proteins in order to obtain a mixture of peptides; and •d) analysing this mixture of peptides by targeted mass spectrometry, the detection of at least one peptide originating from the protein PBP2a (SEQ ID NO. 1) or PBP2c (SEQ ID NO. 2) during this analysis step being indicative of the methicillin resistance of the Staphylococcus aureus strain present in the biological sample.
    Type: Application
    Filed: January 11, 2023
    Publication date: March 6, 2025
    Applicants: UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE NORMALE SUPERIEURE DE LYON, HOSPICES CIVILS DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (Institut National de la Santé et de la Recherche Médicale), WEEZION
    Inventors: Jérôme LEMOINE, Francis DEFORET, François VANDENESCH, Olivier DAUWALDER
  • Patent number: 12241151
    Abstract: The invention concerns a method for manufacturing an aircraft part, the part comprising a monocrystalline nickel-based superalloy substrate, the method consecutively implementing the steps of moulding the part at a moulding temperature greater than the melting temperature of the superalloy, and cooling the part, such that the monocrystalline superalloy has a ? phase and a ? phase, solution heat treatment of the part at a first temperature between the solves temperature of the ?? phase and the melting temperature of the superalloy, homogenising the crystalline structure or the part, cooling the part to ambient temperature, first tempering and second tempering.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: March 4, 2025
    Assignees: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET D'AEROTECHNIQUE DE POITIERS, UNIVERSITE DE POITIERS
    Inventors: Satoshi Utada, Joël Delautre, Sarah Hamadi, Jonathan Cormier, Patrick Villechaise, Jérémy Rame
  • Patent number: 12240984
    Abstract: The invention relates a process for preparing an aqueous gel ink with fixed color comprising the following steps: (i) preparing a gel-based matrix of aqueous ink; (ii) preparing an aqueous suspension of gold or silver nanoparticles with a fixed color; (iii) adding the aqueous suspension of gold or silver nanoparticles obtained in step (ii) to the gel-based matrix of aqueous ink obtained in step (i).
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: March 4, 2025
    Assignees: SOCIETE BIC, UNIVERSITÉ DE HAUTE-ALSACE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Olivier Albenge, Romain Metillon, Karine Mougin, Feriel Ghellal, Arnaud Spangenberg
  • Patent number: 12242184
    Abstract: The present invention pertains to the field of nanoimprint lithography (NIL) processes and more specifically to a soft NIL process used for providing a sol-gel patterned layer on a substrate. Specifically, this process comprises a step of adjusting the solvent uptake of the sol-gel film to 10 to 50% vol., preferably between 15 and 40% vol., by varying the relative pressure of the solvent while a soft mould is applied onto the substrate coated with the sol-gel film.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: March 4, 2025
    Assignees: UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, UNIVERSITE PARIS-SACLAY
    Inventors: David Grosso, Marco Faustini, Olivier Dalstein, Andréa Cattoni, Thomas Bottein
  • Patent number: 12239759
    Abstract: A composition for the adhesion of biological tissues to one another, for the adhesion of a material to a biological tissue, for the adhesion of an adhesive or of a substance to the surface of a biological tissue, for blocking an orifice in a biological tissue, for reinforcing a biological tissue and/or for fixing and stabilising a biological tissue. A monomer that is polymerisable under the effect of ultraviolet (UV) radiation and in that the viscosity of said composition is less than 10 mPa·s at 20° C.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: March 4, 2025
    Assignees: COHESIVES, UNIVERSITE DE PAU ET DU PAYS DE L'ADOUR, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Bertrand Perrin, Christophe Derail, Laetitia Badie, Eric Papon
  • Patent number: 12244952
    Abstract: A system and a method for single-shot compressed optical-streaking ultra-high-speed imaging, the system comprising a spatial encoding module spatially encoding the transient event with a binary pseudo-random pattern into spatially encoded frames; a galvanometer scanner temporally shearing the spatially encoded frames; and a CMOS camera receiving the temporally sheared spatially encoded frames, during one exposure time of the camera, for reconstructing the transient event. The method comprises spatial encoding a transient event; temporal shearing resulting spatially encoded frames of the event, spatio-temporal integration, and reconstruction.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: March 4, 2025
    Assignee: INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jinyang Liang, Xianglei Liu, Fiorenzo Vetrone
  • Patent number: 12242112
    Abstract: An electro-optical conversion system including an opto-mechanical conversion device which includes a ring cavity formed by an optical waveguide which extends along an annular closed curve, a micromechanical resonator that comprises at least one microbeam, and a zipper type element integrated into the ring cavity, the zipper type element including a first arm made on a portion of the ring waveguide and a second arm made on the microbeam. The conversion system also includes a capacitor with first and second electrodes separated by a gap which varies when the microbeam oscillates.
    Type: Grant
    Filed: April 19, 2022
    Date of Patent: March 4, 2025
    Assignees: COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE PARIS
    Inventors: Sébastien Hentz, Ivan Favero, Guillaume Jourdan, Julien Renard, Nicolas Roch
  • Publication number: 20250069633
    Abstract: A magneto resistive memory device including a memory array with at least one bit line (BL) and at least one source line (SL, SLB), the bit line (BL) and the at least one source line (SL, SLB) associated with a plurality of memory cells each presenting a magnetic tunnel junction and each presenting at least one selection transistor (RT) to selectively connect the bit line (BL). The memory array also includes a peripheral block configured to apply a first voltage (Vread) greater than ground voltage (Vss) on the bit line (BL) and applying a second voltage (VSL) greater than the first voltage (Vread) on the at least one source line (SL, SLB). The state stored in the selected cell is detected by using a sense amplifier (SA) of the peripheral block associated with the at least one bit line (BL) to sense the current flowing in the bit line (BL).
    Type: Application
    Filed: December 28, 2022
    Publication date: February 27, 2025
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Victorien BRECTE, Julien LOUCHE, Fabien LEROY
  • Publication number: 20250066700
    Abstract: A method for preparing a fermented grape marc, which includes the following steps: preparing a grape marc infusion by placing grape marc in contact with water and optionally with a source of sugar chosen among sucrose, glucose syrup, or concentrated grape must; placing the grape marc infusion in contact with a scoby (also called “kombucha microbial consortium”) and optionally with kombucha; fermenting the grape marc infusion for a period ranging from 5 to 35 days, and preferably from 7 to 12 days. Also, fermented grape marc obtainable according to the method, as well as to the use thereof in dietary, nutraceutical, or nutricosmetic supplements, or in dermocosmetic products.
    Type: Application
    Filed: December 15, 2022
    Publication date: February 27, 2025
    Applicants: INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, UNIVERSITE TOULOUSE III – PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Patricia TAILLANDIER, Sandra BEAUFORT, Jalloul BOUAJILA, Agathe JUPPEAU, Isaura CACERES
  • Publication number: 20250064993
    Abstract: Novel bispidine-based compounds including at least an optionally substituted ethanoic acid moiety at the N7-position of the bispidine scaffold, these bispidine-based compounds representing metal chelating ligands able to form metallic complexes having good properties in terms of relaxivity and stability, to complexes including a metal ion complexed with these bispidine-based compounds, and to the use of these bispidine-based compounds in the field of medical imaging or therapy, and more specifically MRI (magnetic resonance imaging) contrast agents and/or nuclear imaging agents for PET (positron emission tomography) and/or SPECT (single photon emission tomography).
    Type: Application
    Filed: December 23, 2022
    Publication date: February 27, 2025
    Applicants: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Loïc CHARBONNIERE, Maryame SY, Eva JAKAB TÓTH, Aline NONAT