Patents Assigned to SCIENTIFIQUE (CNRS)
  • Publication number: 20250065296
    Abstract: A method for manufacturing a porous monolith includes: forming a sol including a sol-gel precursor in aqueous solution; at least partially filling with previously formed sol an enclosure and at least one mould contained in the enclosure, the mould including at least one opening into the sol after filling; forming a sol-gel matrix in the enclosure from the sol; removing the mould with the sol-gel matrix contained in the mould from the enclosure; and forming a porous monolith from the sol-gel matrix contained in the mould, wherein the formation of the sol, the sol-gel matrix, and the porous monolith is performed by a sol-gel process.
    Type: Application
    Filed: December 22, 2022
    Publication date: February 27, 2025
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Laurent MUGHERLI, Marc MALEVAL, Maartine MAYNE
  • Publication number: 20250066411
    Abstract: The present invention relates to new glycomimetic molecules which selectively bind to the L-SIGN receptor, finding application in the medical field and, in particular, in the prevention and treatment of viral infections, in the immunotherapy of liver tumors and in the treatment of immune diseases.
    Type: Application
    Filed: October 24, 2024
    Publication date: February 27, 2025
    Applicants: UNIVERSITA’ DEGLI STUDI DI MILANO, UNIVERSITÉ GRENOBLE ALPES, COMMISSARIAT A L’ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Anna BERNARDI, Sara POLLASTRI, Clara DELAUNAY, Michel THÉPAUT, Franck FIESCHI, Gianluca CAVAZZOLI
  • Publication number: 20250067597
    Abstract: The invention is a method for processing a calibration spectrum acquired by a spectrometric detector of X or gamma photons. The method comprises a taking into account of a parametric form of a calibration function, the calibration function linking the rank of an energy channel to an energy value. The method comprises a confrontation between the channels of the peaks of the calibration spectrum and emission energies of calibration isotopes. The confrontation makes it possible to define the values of the parameters of the calibration function.
    Type: Application
    Filed: December 29, 2022
    Publication date: February 27, 2025
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRALESUPELEC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SACLAY
    Inventors: Kélian THIS, Adrien FRIGERIO, Sébastien COLAS, Laurent LE BRUSQUET
  • Patent number: 12233041
    Abstract: Compounds of general formula: wherein R0A and R0B are independently selected from hydrogen and pharmaceutically acceptable cations; and RA and RB are identical and selected from amide, carbamate, sulphonamide, azido, cyano and halide. Also, a pharmaceutical composition including one of the compounds. The composition may also include another active ingredient, especially an antineoplastic agent. Further a compound or a composition for use as a medicament, especially a compound or a composition for use in the treatment of a proliferative disease such as for example cancer.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: February 25, 2025
    Assignees: UNIVERSITÉ DE NANTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DU MANS
    Inventors: Fabrice Fleury, Alexandre Demeyer, Pierre Weigel, Benoit Chenais, Monique Mathé, Jacques Lebreton
  • Patent number: 12235153
    Abstract: A system for controlling the activation/deactivation of an electromagnetic shielding screen of a porthole or a protective window of an optoelectronic equipment, which includes, a radiofrequency electromagnetic sensor, with a bandwidth adapted to a cut-off band of said shielding screen corresponding to a range of electromagnetic fields to be blocked, connected to a detector-rectifier with a sensitivity higher than a minimum value of the power of an electromagnetic field to be blocked by means of said shielding screen and a device for activating/deactivating said electromagnetic shielding screen, said detector-rectifier being configured, in the presence of the electromagnetic field with a power exceeding said minimum value, to activate said device for activating/deactivating the electromagnetic shielding screen by capturing the electromagnetic energy supplied by said electromagnetic fields with a power exceeding said minimum value.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: February 25, 2025
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES, SAFRAN ELECTRONICS & DEFENSE
    Inventors: Quentin Tricas, Patrice Foutrel, Philippe Besnier, Xavier Castel, Claire Le Paven
  • Patent number: 12234328
    Abstract: Polyethylene composition comprising at least 50 wt. % of polyethylene based on the total weight of the polyethylene composition, and having a density of at least 0.910 g/cm3; a melt index MI2 ranging from 3.0 to 60.0 g/10 min; an unsaturation index higher than 2,000 wherein the unsaturation index is the product of the Mn in Dalton and the vinyl unsaturation units per 1,000 carbon atoms as determined by ASTM D6248-98:2004; a complex viscosity at 0.1 rad/sec at 190° C. ranging from 200 to 20,000 Pa·s; and a ratio of complex viscosity at a frequency of 0.01 rad/sec to the complex viscosity at a frequency of 100 rad/sec of at most 8.0, said ratio being measured at 190° C.
    Type: Grant
    Filed: February 1, 2023
    Date of Patent: February 25, 2025
    Assignees: TOTALENERGIES ONETECH, CENTRE NATIONAL DE LARECHERCHE SCIENTIFIQUE(CNRS), UNIVERSITÉ CLAUDE BERNARDLYON 1 (UCBL), UNIVERSITÉ JEAN MONNETSAINT-ETIENNE, INSTITUT NATIONAL DESSCIENCES APPLIQUÉES DE LYON(INSA LYON)
    Inventors: Olivier Lhost, Yves Trolez, Pascal Navez, Philippe Cassagnau, Karim Delage, Mohammad Abou-Taha
  • Patent number: 12232883
    Abstract: The method of modulating epileptogenicity in a brain of an epileptic patient includes: providing a virtual brain; providing a model of an epileptogenic and of a propagation zones and loading the models in the virtual brain to create a virtual epileptic brain; acquiring data of the brain of the epileptic patient; identifying, in the data, a location of at least one possible epileptogenic zone; fitting the virtual epileptic brain against the data acquired from the epileptic patient and parametrizing the at least one possible epileptogenic zone in the virtual epileptic brain as an epileptogenic zone; and simulating, within the virtual epileptic brain, the effect of a network modulation mimicking a clinical intervention of the brain of the patient.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: February 25, 2025
    Assignees: UNIVERSITE D'AIX MARSEILLE (AMU), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ASSISTANCE PUBLIQUE—HOPITAUX DE MARSEILLE (AP-HM), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Viktor Jirsa, Christophe Bernard, Fabrice Bartolomei, Maxime Guye
  • Publication number: 20250061585
    Abstract: The invention relates to a method for real-time tracking of the placement of a camera with respect to a 3D model comprising a keyframe base comprising a first thread of execution making it possible to estimate the current placement of the camera from a selected keyframe, characterized in that the method further comprises a step of analyzing the quality of the estimation of the placement of the camera from the image stored in a buffer memory, and a step of analyzing the sharpness of the image stored in the buffer memory from data representative of the movement of the camera, and if the quality of the estimation of the placement of the camera from the stored image and the sharpness of the stored image conform to predetermined criteria, a step of adding the image stored in the buffer memory to the keyframe base as a new keyframe.
    Type: Application
    Filed: December 14, 2022
    Publication date: February 20, 2025
    Applicants: SURGAR, UNIVERSITÉ CLERMONT AUVERGNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CLERMONT AUVERGNE INP
    Inventors: Adrien BARTOLI, Kilian CHANDELON
  • Publication number: 20250062342
    Abstract: A method for delithiating a lithium and transition metal nitride. The method involves mixing an oxidising agent with the lithium and transition metal nitride and recovering the material obtained. The transition metal may be Mn, Fe, Co, Ni, Cu, or a mixture thereof. The material obtained by the method may be used as a negative electrode material for a lithium-ion battery.
    Type: Application
    Filed: December 23, 2022
    Publication date: February 20, 2025
    Applicants: AMPERE S.A.S., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS EST CRETEIL VAL DE MARNE
    Inventors: Nicolas EMERY, Olivier NGUYEN, Jean-Pierre PEREIRA-RAMOS, Yanlong ZHOU
  • Patent number: 12227550
    Abstract: The present invention relates to a modified cytokine of the TNF superfamily, with reduced activity to its receptor, wherein said modified cytokine is specifically delivered to target cells. Preferably, said modified cytokine is a single chain variant of the TNF superfamily, even more preferably, one or more of the chains can-y one or more mutations, resulting in a low affinity to the receptor, wherein said mutant cytokine is specifically delivered to target cells. The targeting is realized by fusion of the modified cytokine of the TNF superfamily to a targeting moiety, preferably an antibody or antibody-like molecule. The invention relates further to the use of such targeted modified cytokine of the TNF superfamily to treat diseases.
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: February 18, 2025
    Assignees: VIB VZW, UNIVERSITEIT GENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE MONTPELLIER, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE MONTPELLIER
    Inventors: Jan Tavernier, Jennyfer Bultinck, Frank Peelman, Gilles Uze
  • Patent number: 12228340
    Abstract: A cold crucible usable in the field of high-temperature production of monocrystalline materials. The cold crucible includes: a cold cage which has sectors made of a material having good electrical conductivity and in which a charge is melted, and a cooling device with heat transfer fluid, configured to cool each segment of the cold cage from the inside. The cold crucible is essentially such that it further includes at least one device for generating a static magnetic field, each generating device being housed inside one of the sectors of the cold crucible. Each static magnetic field thus generated having the effect of slowing down the electromagnetic stirring of the molten charge, such that it is possible to produce monocrystalline ingots of significantly larger diameter than the diameter of the seed initiating their growth.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: February 18, 2025
    Assignees: INSTITUT POLYTECHNIQUE DE GRENOBLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPES
    Inventors: Kader Zaidat, Christian Garnier, Ghatfan Hasan
  • Patent number: 12227612
    Abstract: The present invention relates to compositions (self-thermally) curable on demand under the triggering action of UV-visible to near-infrared irradiation of moderate intensity, method of using same for accelerated photopolyaddition of cyclic ether-amine resins or ultrafast dark curing of cyclic ether-amine resins, and articles obtained by such method. The invention also relates to a resin casting, film or coated substrate, and an adhesive layeror bonding agent, comprising acyclic ether-amine resin obtained by an accelerated curing process according to the invention. The invention additionally relates to the use of a composition of the invention for increasing the delamination strength of laminated composite materials.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: February 18, 2025
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE HAUTE-ALSACE
    Inventors: Patxi Garra, Jacques Lalevée, Fabrice Morlet-Savary, Céline Dietlin, Aurore Caron
  • Patent number: 12230240
    Abstract: A method and a device for controlling the propagation of acoustic waves in the vicinity of a wall, the method and device implementing a master device for controlling a set Nc of cells primarily made up of a speaker, a set of Nm microphones connected to the speaker, and a control unit, by means of control laws that determine the intensity of the electrical signal that must be sent to each speaker so as to obtain a target determined generalized acoustic impedance for each speaker, such that a fraction of the acoustic waves is absorbed by the membrane of each speaker.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: February 18, 2025
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET DES MICROTECHNIQUES (ENSMM), UNIVERSITE DE FRANCHE-COMTE
    Inventors: Morvan Ouisse, Manuel Collet, Gaël Matten
  • Patent number: 12228498
    Abstract: The invention is a device and method for detecting an analyte in a medium. An exciting light source produces an exciting light wave, which propagates to the medium and heats the latter. The device comprises a transducer for detecting the heating of the medium. According to one embodiment, the transducer is a thermal transducer, configured to detect a variation in the temperature of the medium. According to another embodiment, the transducer is an acoustic transducer, configured to detect a photoacoustic wave propagating from the medium. Whatever the embodiment, the transducer employs a membrane, on which a waveguide is placed. The waveguide comprises a resonant optical cavity. Transduction is achieved by analyzing a variation in a resonant wavelength of the optical cavity.
    Type: Grant
    Filed: December 24, 2020
    Date of Patent: February 18, 2025
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT POLYTECHNIQUE DE GRENOBLE
    Inventors: Thomas Lauwers, Skandar Basrour, Jean-Guillaume Coutard, Alain Gliere, Guillaume Laffont
  • Publication number: 20250052866
    Abstract: A lidar system based on measuring a time-of-flight, including: an emission device configured to emit light pulses towards a scene at an angle greater than or equal to 5°; a reception device including: o a photodetector configured to receive pulses reflected or backscattered by at least one element of the scene and to convert the pulses into an electrical signal, an amplification circuit configured to amplify the electrical signal, a processing unit for processing the amplified electrical signal, configured to digitize the amplified electrical signal and determine a distance from the at least one element based on the digitized amplified electrical signal, the amplification circuit including a transimpedance amplifier, a transformer including a primary and a secondary, a capacitor and an inductor arranged in series with the capacitor.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 13, 2025
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SACLAY
    Inventor: Jean-Paul CROMIERES
  • Publication number: 20250051403
    Abstract: The present invention relates to antimicrobial peptides, variants and chemical analogues thereof; in particular, a peptide of 20 amino acids, named Michelicin, having the sequence RVCVRICRNGRCYRRCWNT, derived from a longer precursor with a BRICHOS domain from the marine worm Capitella. The peptide has several cysteines which form disulfide bridges and provide stability in salt conditions. Several derivatives and analogues were produced. The peptide and the derivatives show antimicrobial activity against a wide range of bacteria. The application also concerns nucleic acid sequences encoding these, pharmaceutical composition and to their use as a drug, preservative and disinfectant.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 13, 2025
    Applicants: UNIVERSITE DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX MARSEILLE, SORBONNE UNIVERSITE, ECOLE CENTRALE DE MARSEILLE
    Inventors: Aurélie TASIEMSKI, Céline WICHLACZ, Marc MARESCA, Stéphane CANAAN, Jean-François CAVALIER, Kamel MABROUK, Stéphane HOURDEZ
  • Publication number: 20250055418
    Abstract: A process for maximum power point tracking of a photovoltaic module, which includes monitoring the module's degradation by: for a periodicity n1?t0 with n1>1 constant or variable, steps of measuring parameters I and V of the module for points offset in voltage voltage VMPP+? and VMPP?? over the curve I(V) relative to the maximum power point MPP, calculating the slope dI/dV+ at the point VMPP+? and the slope dI/dV? at the point and VMPP?? and recording of the data with the MPP; for a periodicity n2?t0 with n2?n1 of > of steps of measuring values I and V by sweeping the curve I(V) and calculating and storing the module's parameters and values; one or several steps of calculating, tracing and displaying of (p/2) curves of data pairs based on p measured and calculated parameters; and one or more steps of detecting degradation from the measured and calculated parameters.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 13, 2025
    Applicants: ELECTRICITE DE FRANCE, INSTITUT PHOTOVOLTAIQUE D'ILE DE FRANCE (IPVF), TOTALENERGIES ONETECH, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -, ECOLE POLYTECHNIQUE
    Inventors: Jean-Baptiste PUEL, Arthur JULIEN, Jean-François GUILLEMOLES
  • Publication number: 20250049985
    Abstract: An adhesive composition including a calcium phosphate ceramic selected from tetracalcium phosphate and alpha-tricalcium phosphate, phosphorylated serine, polydopamine, and an aqueous solvent. Also, a kit for preparing the adhesive composition, which includes the calcium phosphate ceramic, phosphorylated serine, and polydopamine and a method for preparing the adhesive composition, as well as the uses thereof.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 13, 2025
    Applicants: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE, UNIVERSITE DE LILLE, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRALE LILLE INSTITUT
    Inventors: Mathias SCHLUND, Feng CHAI, Joël LYSKAWA, Joël FERRI
  • Patent number: 12220743
    Abstract: Equipment for selectively depositing, by shockwave-induced spraying, at least one particle on a deposition surface of a receiver substrate. The equipment including at least one laser source that emits a laser beam, a substrate carrier to which the substrate is fastened, a shockwave-generating layer having a first surface oriented toward the laser beam and a second surface oriented toward the deposition surface of the substrate, an optical system for directing and focusing the laser beam toward a focal region of the first surface. The second surface including a plurality of cavities, each cavity housing at least one particle. The laser beam generates a plasma in the focal region on the first surface and a shockwave that propagates within the generating layer from the first surface to the second surface in order to spray at least one particle in the direction of the deposition surface of the substrate.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: February 11, 2025
    Assignees: UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, ECOLE NATIONALE SUPERIEURE D'ARTS ET METIERS, INSTITUT POLYTECHNIQUE DE BORDEAUX
    Inventor: Robin Kromer
  • Patent number: 12220723
    Abstract: The invention relates to a method for producing, applying and fixing a multilayer surface coating (2a, 3a) on at least one surface (1a) to be coated of a host substrate (1) in order to produce a host substrate assembly. Starting with a fixative product (2) and a functional product (3) based on single-walled or multi-walled graphene, the method consists in successively applying: a layer (2a) of fixative product to the or to each surface (1a) to be coated of the host substrate (1); and a layer of the functional product to said fixative layer (2a). The assembly can be finished with a protective layer deposited directly onto the layer (3a) that contains the functional product. The invention also relates to a host substrate assembly which can be obtained by said method, a heating element, an anti-corrosion and/or anti-fouling/dirt-repelling element and a hydrophobic element each comprising such an assembly.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: February 11, 2025
    Assignees: BLACKLEAF, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE STRASBOURG
    Inventors: Housseinou Ba, Armel Bahouka, Yannick Lafue, Cuong Pham-Huu