Abstract: High cost of biotherapy drug makes it unaffordable for patients to seek treatments. Further, access to information related to new low-cost alternatives like Biosimilars and Interchangeable may not be available with the physician at the time of consultation. Most of the conventional approaches aims to select an alternative biosimilar for a reference drug without considering patient's information. The present disclosure recommends a list of low-cost alternatives to high-cost reference drugs thereby enabling the physician to get timely and updated information on development of Biosimilars. The solution leverages Natural Language Processing (NLP) technology to extract known adverse events for a reference drug and a relative scoring based technique to identify and optimum alternative to prescribed biologics. The capability of the solution is further extended to identify secondary adverse events due to multiple drugs, thereby providing a clinical decision support system to help physicians take an informed decision.

Abstract: This disclosure provides a Kalman filter based predictive jitter buffer adaptation for smooth live video streaming. In the present disclosure, at receiver of a live video steaming system, reassembly of received data packets is performed to reconstruct different types of encoded frames transmitted by a transmitter. The different types of encoded frames are Full encoded frames in basic state and Delta encoded frames. To tackle data packet loss, the receiver is also equipped with a frugal yet efficient loss handling mechanism for both basic and delta frames. To achieve smooth rendering of the live video, the receiver employs a Kalman Filter based Jitter Buffer Adaptation mechanism. The Kalman Filter based Jitter Buffer Adaptation mechanism observes variability in arrival time of the open-loop best-effort traffic and adapts a jitter-buffer based on future end-to-end delay estimates. Thus, smoothness of streaming is preserved at the receiving end augmented with robust loss-resilience.

Abstract: A system can include a sensor assembly and a wellhead flange sized to receive the sensor assembly. The system can also include a seal that can be positioned between the sensor assembly and the wellhead flange for sealing the wellhead flange from an external environment. The system can also include an inner coil that can be positioned within the sensor assembly. The inner coil may be able to communicate wirelessly with an outer coil that can be positioned around the sensor assembly for transmitting data and power with respect to the wellhead flange. The system can also include a sensor positionable in a through bore of the wellhead flange. The sensor can be coupled with the inner coil for transmitting and receiving data and power with respect to the wellhead flange.

Abstract: An apparatus for interrogating a media to be analyzed, such as an avian egg, is provided. Such an apparatus includes an emitter assembly configured to emit light toward a media. The emitter assembly has a first emitter source configured to emit a first light signal and a second emitter source configured to emit a second light signal. The first and second light signals are transmitted through the media in phase quadrature. A detector assembly is configured to detect the first and second light signals transmitted through the media. The detector assembly is further configured to resolve a relative or absolute amplitude of each of the first and second light signals. A processor is configured to process the detected signal to identify a property of the media using at least one of the relative and absolute amplitudes of the first and second light signals. An associated method is also provided.

Abstract: Real-time monitored computed tomography (CT) reconstruction for reducing a radiation does. During helical CT scanning of a target object, projections may be acquired in either a full mode which subjects the target object to a full radiation dose, or a reduced mode which subjects the target object to a reduced radiation dose (e.g., by reducing the number of projections acquired, reducing the exposure time, etc.). After a sector is acquired in the full mode, a slice of the target object that is influenced by that sector is identified, and a CT image of that slice is reconstructed using projections that have been previously acquired for that slice. When a stopping rule is satisfied based on this partial reconstruction, the full mode is switched to the reduced mode, and at least one subsequent sector is acquired in the reduced mode.

Abstract: Implementations of the of the present stripping corner may include a first forward surface, a second forward surface, hingedly connected to the first forward surface, a first rearward surface, hingedly connected to the first forward surface, a second rearward surface hingedly connected to the second forward surface, and an extender coupling the first rearward surface to the second rearward surface. The extender may be configured to receive an input torque about a first axis and may be configured to provide an output force along a second axis. The first axis may be substantially perpendicular to the second axis.

Abstract: A computer-implemented method that includes receiving a user command including one or more criteria characteristics in association with an account and detecting an occurrence of a transaction from the account. The transaction is associated with one or more purchase characteristics. The method includes determining whether the one or more purchase characteristics of the transaction match the one or more criteria characteristics, and recording a modified version of the one or more purchase characteristics of the transaction on a ledger of the account in response to determining the one or more purchase characteristics match the one or more criteria characteristics. The method includes recording an unmodified version of the one or more purchase characteristics of the transaction on the ledger in response to determining the one or more purchase characteristics do not match the one or more criteria characteristics.

Abstract: Systems, methods, and other embodiments associated with associated with automatic two-way generation and synchronization of notebook and pipeline are described. In one embodiment, a computer-implemented method includes: identifying a difference between pipeline and notebook representations of application logic, wherein the difference is one of (i) a notebook paragraph without a corresponding pipeline node and (ii) a pipeline node without a corresponding notebook paragraph; synchronizing the pipeline representation and notebook representation by, for the notebook paragraph that does not have a corresponding pipeline node, automatically generating a new pipeline node in the pipeline representation, and for the pipeline node that does not have a corresponding notebook paragraph, automatically generating a new notebook paragraph in the notebook representation; and updating either a pipeline user interface to show the new pipeline node or a notebook user interface to show the new notebook paragraph.

Abstract: A system, process, and computer-readable medium for securely transferring user personal identification information (PII) across platforms, based on specific permissions, are described. One or more aspects provide greater control, to a user, of when that user's PII may be released from a secure storage in a first platform and securely provided to a second platform. The timing of those releases of the PII may be controlled by specific authorizations from the user via one or more processes. Also, in addition to improving the security associated with the PII transferred between platforms, one or more aspects improve users' experiences by permitting controlled reuse of users' PII to simplify how users provide their PII to separate processes being performed on separate platforms.

Abstract: Embodiments of the invention are directed to systems and methods for validating transactions using a cryptogram. One embodiment of the invention is directed to a method of processing a remote transaction initiated by a communication device provisioned with a token. The method comprises receiving, by a service provider computer, from an application on the communication device, a request for a token authentication cryptogram, wherein the token authentication cryptogram includes encrypted user exclusive data. The service provider computer may generate the token authentication cryptogram to include the user exclusive data. The service provider computer may send the token authentication cryptogram to the application, where the token authentication cryptogram can be used to validate the transaction, and the user exclusive data is extracted from the token authentication cryptogram during validation.

Abstract: Systems and methods for fault tolerant digital payments are disclosed. The system comprises a computing system that can automatically determine if payments should be processed using a digital payment processing system, or using a blockchain. When the system detects that communication with the digital payment processing system has been interrupted, the system may facilitate transactions through the blockchain. In particular, the system may receive private keys from mobile devices of customers, which can be used to make payments on the blockchain.

Abstract: Methods and systems for locational visualization of financial statements are described. In an example, a method may receive, in a financial institution system, a request to display a record associated with a financial transaction, determine a location of a merchant associated with the financial transaction using merchant information, request, from an online mapping service, a customizable map interface associated with the location of the merchant, receive the customizable map interface, and display the customizable map interface integrated into the record associated with the financial transaction.

Abstract: Systems and methods for controlling a vertical pumping unit are provided. The method includes a self-learning phase and a running phase, wherein the self-learning phase includes obtaining a self-learning result and the running phase includes controlling a motor of the vertical pumping unit to run according to the self-learning result and preset running parameters. The method enables the vertical pumping unit to adjust running parameters of the running phase according to the self-learning results, avoid the accumulation of errors effectively so that changes in stroke length and stroke frequency caused by the motor V-belt, load belt extension and retraction and other elastic links are limited to a minimum range so as to ensure the running accuracy of the vertical pumping unit.

Abstract: The invention features modified alphavirus or flavivirus virus-like particles (VLPs). The invention provides methods, compositions, and kits featuring the modified VLPs. The invention also features methods for enhancing production of modified VLPs for use in the prevention or treatment of alphavirus and flavivirus-mediated diseases. The invention also provides methods for delivering agents to a cell using the modified VLPs.

Abstract: The present disclosure is directed to systems and processes for adaptively optimizing query execution. To improve efficiency and reduce costs of executing queries, machine learning may be utilized to automatically choose or adjust the processing blocks used to execute or process queries based on the nature of the cloud processing outputs and client preferences, among other considerations. A machine learning engine may group queries together into topics based on characteristics of the queries. The machine learning engine may receive execution statistics for the topics and, using the execution statistics, identify which topics enhance or optimize query execution. The machine learning engine may determine which topics may be executed by which processing blocks, at which times of day, and on which platforms, among other considerations in order to enhance or optimize cost or processing efficiency according to client-specified parameters.

Abstract: A system and method for handling slag in a slag pit includes an equilibrium or balance crane equipped with a quick connect coupling. A drop-ball fixture and drop-ball reduces the size of the slag, as needed, then the boom assembly of the crane releases the drop-ball fixture and engages an excavating tool, such as a clamshell bucket, a bucket, or a grapple. An elevated control station provides an operator with improved line-of-sight visibility.

Abstract: Disclosed herein are methods of diagnosing, and treating and/or preventing CD55-deficiency, hyperactivation of complement, angiopathic thrombosis and protein-losing enteropathy (CHAPLE). The method of diagnosing includes: providing a sample from a patient; performing an assay detecting at least one of at least one mutation in a DNA sequence of a CD55 gene, at least one mutation in a RNA sequence of a CD55 transcript, at least one mutation in a DNA sequence of a CD55 complementary-DNA (cDNA), CD55 protein, CD55 protein binding, complement deposition or combination thereof, and diagnosing the patient with CHAPLE. The method of treating and/or preventing at least one symptom of CHAPLE includes: administering an effective amount of a composition comprising at least one complement inhibitor to a subject in need thereof, wherein the composition is effective in treating or preventing at least on symptom of CHAPLE. The disclosure further relates to compositions effective at treating and/or preventing CHAPLE.

Abstract: A system and method are provided which include receiving, from a first application on a user device, an indication that a user has been authenticated and receiving, from a second application on the user device, an indication that the user is detected. The user device receives the indication that the user is detected from a wearable device on the user. Based on receiving the two indications within a time period, a trust token is generated or maintained for the user.

Abstract: Described herein is a network apparatus with secure element and related systems, methods, and apparatuses. A described method includes receiving a request to perform a transaction. The method also includes obtaining confirmation that a network address associated with the request corresponds to a registered physical address. The method further includes obtaining account data and conducting a transaction using the account data.

Abstract: A plurality of flow control nodes are spaced along a production conduit for controlling a flow of formation fluids into the production conduit at different locations in the well. Each flow control node defines a flow path for entry of the formation fluids into the production conduit. A closure is operable to adjust the flow of the formation fluids into the production conduit. A generator at each zone generates electrical power in response to a portion of the flow directed through the generator. An electrical power grid interconnects the plurality of flow control nodes to collectively supply electrical power to the power grid. Each closure and other device components are operable with the electrical power from the power grid.