Abstract: This invention relates to methods and compositions for the attenuation of HIV-1 replication in human cells, and especially in human macrophages. The invention particularly concerns the use of inhibitors of P21 (CDKNIA) expression to attenuate such replication. The invention particularly concerns the use of antisense P21 oligonucleotides, siRNA and/or 2-cyano-3,12-dioxooleana-1,9-dien28-oic (CDDO) to attenuate such replication.
Type:
Application
Filed:
October 12, 2012
Publication date:
May 9, 2013
Applicant:
The United States of America, as represented by Secretary, Department of Health & Human Services
Inventor:
The United States Of America, as Represented By The Secretary, Department Of Health & Human Services
Abstract: The present invention relates to encapsulated breakers and the use of encapsulated breakers for breaking viscosified treatment fluids. One embodiment of the present invention provides a method of providing a viscosified treatment fluid having a first viscosity having a gelling agent, a crosslinking agent, a proppant, an aqueous-base fluid, and an encapsulated breaker composition having an encapsulant that has a poly(meth)acrylate blend; introducing the viscosified treatment fluid in the subterranean formation; creating or enhancing a fracture in a subterranean formation; and allowing the encapsulated breaker composition to release the breaker so as to reduce the viscosity of the viscosified treatment fluid to a second viscosity.
Type:
Application
Filed:
November 9, 2011
Publication date:
May 9, 2013
Applicant:
Halliburton Energy Services, Inc.
Inventors:
Ramesh Muthusamy, Prajakta R. Patil, Nisha A. Pandya
Abstract: Projects of any type require sophisticated management software programs. In reality, these management software programs are provided by various vendors and for different professional fields. For example, scheduling programs for construction professionals, blue print programs for drafting professionals, accounting programs for cost-control professionals. In addition, there are numerous other unofficial and official documents generated by managers of different levels for reporting or track-record-keeping purposes using popular word processing programs and spread-sheet programs. Documents generated by different software programs can only be viewed under the programs they are generated under or compatible programs. This poses a problem in that there is a lack of organized control resulting in difficulty in locating and viewing documents in a timely manner.
Abstract: A server receives a customer service request and customer identification information associated with the customer service request. A home location of the customer is identified based, at least in part, on the customer identification information. An interactive voice response application is selected based, at least in part, on the home location. The selected interactive voice response application is provided to a voice portal, wherein the voice portal services the customer service request.
Type:
Grant
Filed:
January 12, 2010
Date of Patent:
May 7, 2013
Assignee:
American Express Travel Related Services Company, Inc.
Abstract: A system is described for assembling a behavior model of a technology component. The system may include a memory, and a processor. The memory may store a behavior model of a technology component. The processor may to monitor the technology component over a period of time to determine a plurality of parameter values associated with each state of a plurality of states of the technology component. The processor may process the plurality of parameter values associated with each state to determine a baseline parameter value for each state. The processor may assemble the behavior model for the technology component. The behavior model may include each state, the baseline parameter value for each state, and an association between each state and the baseline parameter value for each state. The processor may store the behavior model of the technology component in the memory.
Type:
Grant
Filed:
April 1, 2009
Date of Patent:
May 7, 2013
Assignee:
Acenture Global Services Limited
Inventors:
Teresa S. Tung, Nikki Ann G. Guevarra, Fausto A. Inestroza
Abstract: An online experience of a user is dynamically configured at the micro-regional level based to achieve an objective associated with sales of a product. A catchment zone is determined, which identifies the geographic region associated with the objective and the product. The online user experience for users in the catchment zone is modified to achieve the objective.
Abstract: Systems, methods, and instructions encoded in a computer-readable medium can perform operations related to generating probabilistic information on characteristics of natural fractures of a subterranean formation. Fitted fracture models are generated based on microseismic event data for a subterranean region. The fitted fracture models represent estimated locations of fractures in the subterranean region. A distribution of fracture parameter values is generated based on the fitted fracture models. The distribution includes fracture parameter values and a probability associated with each fracture parameter value. Generating the fitted fracture models may include, for example, fitting a plane, a line or another type of equation to the measured locations of microseismic events. In some implementations, an injection treatment may be simulated and/or designed based on the probability distribution.
Abstract: A downhole fluid analysis tool has a tool housing and a fluid analysis device. The tool housing is deployable downhole and has at least one flow passage for a fluid sample. The fluid analysis device is disposed in the tool housing relative to the flow passage. Inside the device, one or more sources generate a combined input electromagnetic signal across a spectrum of wavelengths, and a routing assembly routes generated signals into the reference and measurement signals. At least one wheel having a plurality of filters is rotated to selectively interpose one or more of the filters in the paths of the reference and measurement signals.
Type:
Grant
Filed:
November 6, 2009
Date of Patent:
May 7, 2013
Assignee:
Precision Energy Services, Inc.
Inventors:
Jess V. Ford, Sean M. Christian, Dennis Roessler, Bryan W. Kasperski, Margaret C. Waid
Abstract: A plurality of affiliated websites are configured to log user interactions. The logs comprise user identification information that allows a profile aggregation service to correlate user interactions across the affiliated websites and to generate respective user profiles. The user profiles may be used to configure the websites. A context aware platform (CAP) website may be configured to provide web services for entities in a business hierarchy. The CAP website may capable of presenting content in one of a plurality of operational modes associated with a geographical granularity of the business hierarchy. In addition, the CAP website may be configurable according to a user profile generated by a profile aggregation service.
Type:
Grant
Filed:
October 1, 2008
Date of Patent:
May 7, 2013
Assignee:
ADP Dealer Services, Inc.
Inventors:
Matt Muilenburg, Stefan Piesche, Keith D. Zackrone
Abstract: A disconnectable mooring assembly for a vessel comprises a mooring buoy and a swivel positioned above the mooring buoy. The mooring buoy is provided with a central member for being anchored to the seabed and comprises a number of passages each adapted for receiving a riser. The mooring buoy further comprises an outer member surrounding the central member and capable of a rotation relative thereto. Said outer member is adapted to be housed in and locked to a corresponding receiving opening of the vessel. The swivel is located above the mooring buoy in such a manner that an interspace is defined between the mooring buoy and the swivel.
Abstract: A process for testing a composition as containing an artemisinin derivative is provided that includes contacting the composition with a reagent made up of a hydrogen bonding polar organic solvent and an acid having a pK value of less than 3.8 at 25° Celsius and capable of acid catalyzing a decomposition reaction of the artemisinin derivative so as to provide a reaction mixture. The reaction mixture is allowed sufficient time at a reaction temperature for the artemisinin derivative to decompose to yield a colored decomposition product discerned by a normal unaided human eye. A kit for testing a composition for an artemisinin derivative according to the process is provided together with instructions for contacting the solvent and the acid with the composition to decompose the artemisinin derivative to yield the colored decomposition.
Type:
Grant
Filed:
November 5, 2008
Date of Patent:
May 7, 2013
Assignee:
The United States of America, as Represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention
Abstract: A temperature and/or wear sensor for brake or clutch devices is designed as a thermocouple in which the conductors (20, 22) that are electrically insulated from each other are arranged inside a friction lining (14) and can be connected to each other so as to be electrically conductive by means of a rotatably mounted brake element (12), clutch element or the like, with which the friction lining can be engaged in order to brake or to depress the clutch (FIG. 1). The conductors can be coupled to an electric oscillating circuit.
Abstract: An embodiment of the present invention comprises a method of cementing comprising: placing a settable composition into a well bore, the settable composition comprising unexpanded perlite, cement kiln dust, and water; and allowing the settable composition to set. Another embodiment of the present invention comprises a method of cementing comprising: placing a settable composition into a well bore, the settable composition comprising ground unexpanded perlite, Portland cement interground with pumicite, and water; and allowing the settable composition to set. Yet another embodiment of the present invention comprises a settable composition comprising: ground unexpanded perlite; cement kiln dust; and water.
Type:
Grant
Filed:
September 7, 2012
Date of Patent:
May 7, 2013
Assignee:
Halliburton Energy Services, Inc.
Inventors:
Chad Brenneis, Jeffery Karcher, Craig W. Roddy
Abstract: Methods, systems and computer readable instructions to provide unbiased real property information to an end-user based on the location of the end-user when the end-user initiates a request for the real property information. The real property information is unbiased because the provider of the real property information searches for information that may adversely affect a potential transaction and provides the information found in the search regardless of the potential effect on a transaction.
Type:
Grant
Filed:
March 31, 2008
Date of Patent:
May 7, 2013
Assignee:
United Services Automobile Association (USAA)
Inventors:
Bradly Jay Billman, Charles Lee Oakes, III, Rickey Dale Burks, Michael Patrick Bueche, Jr.
Abstract: Share of Wallet (“SOW”) is a modeling approach that utilizes various data sources to provide outputs that describe a consumers spending capability, tradeline history including balance transfers, and balance information. These outputs can be appended to data profiles of customers and prospects and can be utilized to support decisions involving prospecting, new applicant evaluation, and customer management across the lifecycle. A SOW score focusing on a consumer's spending capability can be used in the same manner as a credit bureau score.
Type:
Grant
Filed:
May 25, 2012
Date of Patent:
May 7, 2013
Assignee:
American Express Travel Related Services Company, Inc.
Inventors:
Kathleen Haggerty, Benedict O. Okoh, Peter L. Williamson, Chao M. Yuan
Abstract: A portable consumer device having a substrate layer, a protective layer and a diamond-based brittle material layer having an intentionally created unique fissure or cracked patterns or crystal zone boundaries and systems and methods for making and using same are disclosed. The diamond-based brittle material layer includes a diamond material. The unique random fissure or cracked pattern and crystal zone boundaries, or the electromagnetic signature based thereon, of the brittle material layer are detected and used to authenticate the portable consumer device.
Abstract: A system for controlling a speed of each of N variable speed motors with a drive voltage is disclosed, where N is an integer equal to or greater than 1. The system includes (N+1) generators and a switching arrangement configured to directly couple, in a one-to-one relation, the N variable speed motors to the (N+1) generators so that any one of the N variable speed motors is capable of operating in at least a first mode and a second mode. In the first mode the any one of the N variable speed motors is driven with the drive voltage generated by a first generator of at least two of the (N+1) generators, and in the second mode the any one of the N variable speed motors is driven with the drive voltage generated by a second generator of the at least two of the (N+1) generators.
Type:
Grant
Filed:
March 1, 2010
Date of Patent:
May 7, 2013
Assignee:
Bluewater Energy Services B.V.
Inventors:
Jeroen Giesselbach, Clemens Van Der Nat, Pieter Cornelis Burger