Abstract: Methods are provided herein for measuring the mutational frequency of a DNA molecule in cells, for example stem cells or hematopoietic cells such as CD34+ cells or granulocytes. The method includes sequencing corresponding regions of mtDNA from a set of hematopoietic cells, or a set of clonal populations of hematopoietic cells, and comparing the sequence of the corresponding regions of mtDNA from the cells, or clonal populations of cells. The method also includes the comparison of mtDNA sequences with genomic DNA sequences. Also provided are methods for screening for an agent that has a mutagenic effect on a cell. The method includes contacting, or treating, clonal populations of cells with an agent and comparing the sequence of the mtDNA obtained from the treated clonal populations of cells, with the sequence of the corresponding region of mtDNA obtained from a control clonal populations of cells.

Abstract: Lightweight composite particulates and their use in subterranean applications such as production enhancement and completion are provided. In one embodiment a method of forming a lightweight particulate suitable for use as proppant or gravel in a subterranean operation comprising the steps of forming a substantially homogeneous mixture of PET and a filler material; forming the homogeneous mixture into particulates suitable for use in a subterranean environment is provided. Other embodiments provide methods of treating, fracturing, and gravel packing a chosen zone in a subterranean formation.

Abstract: A casket memorabilia compartment assembly adapted to couple to a casket to provide display and/or storage of pictures memorializing the deceased. The memorabilia compartment assembly comprises a panel mountable to the casket for swinging displacement between an inner hanging position within the casket and an outer hanging without the casket. The panel includes a display side exposed when in the outer hanging position. The display side includes a compartment for the display and/or storage of pictures. The outer surface of the compartment is transparent so as to view the pictures within the compartment. The memorabilia compartment assembly can be incorporated into a big body and/or throw used during viewing of the deceased.

Abstract: The present invention provides isolated polypeptides of human p53 that contain mutations. These mutations can be toxic mutations, supertransactivating mutations or tox-suppressor mutations. Further provided by the invention are methods of identifying toxic, supertransactivating, weak transactivating and tox-suppressor mutations as well as methods of identifying compounds that mimic the toxic, supertransactivating and tox-suppressor mutations in human p53. Also provided are methods of inducing toxicity in a cell by administering a polypeptide comprising a supertransactivating or a toxic mutation.

Abstract: Exemplary embodiments relate to cementing operations and, more particularly, to foamed cement compositions, foaming and stabilizing additives, and associated methods. A foaming and stabilizing additive, that comprises a mixture of an alkali salt of an alkyl ether sulfate surfactant, wherein the alkali salt of the alkyl ether sulfate surfactant comprises a mixture of an alkali salt of a C6-10 alkyl ether sulfate surfactant, and an alkali salt of a C2-4 alkyl ether sulfate surfactant, an alkyl or alkene amidopropyl betaine surfactant, an alkyl or alkene amidopropyl dimethylamine oxide surfactant, sodium chloride, and water, is provided. Also provided are foamed cement compositions that comprise the foaming and stabilizing additive, and associated methods.

Abstract: A software product is produced by defining a functional model of the overall software product, designing, based on this functional model, a plurality n of configurations and slices of the software product, wherein a configuration is the entirety or a part of the software product forming an independently testable unit and a slice is a set of functions of the software product constructed together and forming the entirety or part of a configuration. The n slices are independently constructed wherein the first slice forms the first configuration. The second to n-th configurations are formed by integrating the k-th configuration with the (k?1)-th slice, wherein k is 1, . . . n?1 Subsequently a first to n-th configuration are tested independently. This software development approach allows an integration of the overall systems in parts as early as possible and to gradually increase the number of integrated components in a controlled, but manageable fashion.

Abstract: A method and system for removing contaminants from contaminated soil at a site utilizes particle size segregation and particle density segregation to yield a plurality of fractions, whereby each of the fractions are tested and identified for the presence of unacceptable levels of contaminants, and the soil fractions from the contaminated soil at the site corresponding to the identified contaminated fractions are collected for subsequent disposal or treatment, while the remaining untainted soil fractions are homogenized and returned to the site.

Abstract: The present invention is a tire derimming device adapted to separate the rubber portion of a tire from its rim and ring. The derimming device generally comprises a power actuator that contacts and bends the rim until the bead pops from the rim and the rim falls out of the tire thereby separating the rim from the ring. The device further comprises a shearing assembly for cutting the rubber portion of the tire into multiple pieces after the rim has been removed from the tire.

Abstract: A method and apparatus for use in a subterranean well is described. The apparatus typically includes a mandrel and a packing element. The mandrel may have an outer surface and a non-circular cross-section and a the packing element may be arranged about the mandrel, the packing element having a non-circular inner surface matching the mandrel outer surface such that concentric rotation between the mandrel and the packing element is precluded. The apparatus may include slips having cavities to facilitate removal of the apparatus. The apparatus also may include a valve for controlling fluid flow through a hollow mandrel. The valve may include a flapper having at least one tab to engage at least one recession in the mandrel such that rotation between the mandrel and the valve is precluded when the valve is in a closed position. The apparatus may further include a central member which is releaseably attached to the mandrel by a release mechanism.

Abstract: The invention is directed towards mouse-human chimeric variants of CC49 monoclonal antibodies with minimal murine content. A first aspect of the invention provides CDR variants of humanized monoclonal antibody (HuCC49) in which less than all six (three heavy chain and three light chain) Complementarity Determining Regions (CDRs) of CC49 are present. A second aspect of the invention provides SDR variants of humanized monoclonal antibody (HuCC49) in which only Specificity Determining Regions (SDRs) of at least one CDR from CC49 are present. The invention is also directed towards biotechnological methods of making the variants and therapeutic methods of using the variants.

Abstract: The present invention is directed to an apparatus, system and method for collecting, storing and time-stamping telematics data. A programmable logic control unit is described that is connected to one or more sensors mounted on a vehicle to capture, time-stamp and store telematics data. And, upon the happening of a triggering event, time-stamped telematics data is transferred from the control until to an external device via wireless or other communications methods.

Abstract: A method, program and system for administering tests in a distributed data processing network are provided by the present invention. The invention includes combining predetermined test content and multimedia support material into a single encrypted test file. The multimedia support may include visual and audio files for presenting test questions. The invention then exports the encrypted test file to at least one remote test location. The test locations import and decrypt the encrypted test file and load the test content and multimedia support material into a local database. The test is administered on a plurality of client workstations at the testing location, wherein the test may include audio questions and verbal responses by participants. During the course of testing biometric data about test participants is recorded and associated with the test files and participant identification.

Abstract: This invention provides cement compositions that comprise a high alumina cement, vitrified shale, a soluble phosphate, and water sufficient to form a slurry. This invention also presents methods of enhancing the corrosion resistance of a cement composition that comprise the step of adding vitrified shale to the cement composition.

Abstract: A fluid recovery system 10 for collecting formation fluid at the surface of a well 12 includes a downhole jet pump 20 and a surface diaphragm pump 40 having a plurality of diaphragms 42. The jet pump includes a fluid nozzle 22, an intake 24 directing the formation fluid into a jet 26, a mixing tube 28 for mixing the power fluid and the formation fluid, and a diffuser 30 for converting the velocity of the mixed fluid to pressure. A flow meter 50 and a pressure sensor 52 monitor the quantity and pressure of the power fluid to the jet pump.

Abstract: A system for supporting patient care equipment alongside a patient support is provided. In one embodiment, the system includes a plurality of arms supported by a support structure. The arms may be pivoted to either side of the patient support. The arms may be stored in a console. At least one of the arms may carry service conduits that provide medical air, oxygen, vacuum, nitrogen, nitrous oxide, or electricity.

Abstract: The gap sub assembly comprises a pair of electrically conductive subs. Each sub has a threaded pin and box. A pin and box are threaded together to form a connection. An electrically insulating, woven fabric overlies and conforms with the threads of the connection pin. An electrically insulating, annular washer separates the seal faces of the connection. The assembly functions to provide an electrical discontinuity when incorporated into a conductive drill string.

Abstract: An automated banking machine system and method includes ATMs which accept checks and dispense cash to users. The ATMs are operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the ATM in exchange for the deposited check. The ATMs dispense cash responsive to communications with a transaction host.

Abstract: An automated banking machine system and method includes ATMs which accept checks and dispense cash to users. The ATMs are operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the ATM in exchange for the deposited check. The ATMs dispense cash responsive to communications with a transaction host.

Abstract: A system for facilitating a check-cashing transaction in accordance with the present invention comprises a check-cashing apparatus and a host system in communication with the check-cashing apparatus. The check-cashing apparatus has input devices for receiving check data and identification data from a user. The host system includes one or more processors configured to receive check data, identification data, check image and membership data input by the user at the check-cashing apparatus. The host system can authenticate the identification data by applying a validation algorithm to the identification data or by cross-referencing the data against one or more databases containing validated identification data. If the check cashing apparatus includes a device for capturing biometric information, the identification data can also be authenticated by comparing the biometric information captured at the time of the transaction with stored biometric information relating to the user.