Abstract: A bone tissue regeneration product, a method for preparing the bone tissue regeneration product and, and a method for repairing a bone defect. The new use of IGSF10 of the present disclosure can reduce the effective concentration of BMP without obvious adverse reactions, thereby exploring a method to promote bone tissue regeneration and providing new ideas for the treatment of bone defects. The present disclosure is capable of promoting non-bone related cells to produce bones; the method of the present disclosure is also capable of inhibiting the bone loss in inflammatory environments.

Abstract: The present invention relates to a substrate-triggered single crystal superalloy directional solidification process, including: (1) preparing a single crystal substrate material having crystallographic characteristics that match crystallographic characteristics of the single crystal superalloy; (2) fabricating a single crystal substrate chilling plate using the obtained single crystal substrate material; and (3) applying the obtained single crystal substrate chilling plate in a directional solidification apparatus, and then preparing a single crystal alloy product by performing superalloy melting and directional solidification.

Abstract: A heterogeneous image registration method includes: performing edge detection on collected images, in combination with a curvature scale space strategy to extract contour curved segments in an edge image. Implementing a feature point detection strategy based on global and local curvature detecting feature points in the contour curved segments, and obtaining the nearest minimum local curvature of the feature points pointing to starting and end points of the contour, respectively. Calculating the number of neighborhood sampling points and neighborhood auxiliary feature points of neighborhoods on both edges of each of the feature points according to the nearest minimum local curvature. Using neighborhood auxiliary feature points and feature points to form a feature triangle, calculating an angle bisector vector and a main direction corresponding to the feature point in the feature triangle.

Abstract: The invention provides a colonic microbiota responsive polymer characterized in that it is prepared by the polymerization of a response monomer and a linking monomer, wherein the response monomer is a cellobiose with a B-(1,4)-glucoside bond or/and a lactose with a p-galactoside bond; the linking monomer is a monomer that reacts with the hydroxyl group of the response monomer to form an ester or ether directly or by a crosslinking agent. The invention also provides a method for preparation of a colonic microbiota responsive polymer, a degradable film based on the polymer and a preparation method thereof. By means of the characteristics that B-(1,4)-glucoside bond provided by cellobiose or/and p-galactoside bond provided by lactose monomer unit in the polymer can specifically respond to the high abundance of microbiotas (p-glucosidase or/and p-galactosidase) in the colon to specifically degrade in the colon, a colon-targeted delivery system for diagnosis and treatment of colon diseases is constructed.

Abstract: Provided is a media processing method. The method is used for uploading a function provided by a user or a third party and obtaining media processing parameters provided by the user. The method includes the following steps: receiving the description information of the media processing and determining whether a function that fulfills the requirement of the description information exists in a system; in a case where the function that fulfills the requirement of the description information exists, selecting the function that fulfills the requirement of the description information from the system; and in a case where the function that fulfills the requirement of the description information does not exist, selecting the function from the system according to the priority or selecting the function that fulfills the requirement of the description information from outside the system.

Abstract: The present invention provides an active distribution network physics-information fusion control method for a hybrid system model includes an initialization time being a starting time, predicting power output and load of a feeder intermittent distributed power supply within a control time period T, calculating a feeder exchange power deviation variation ?P(t) during the control time period, if being a fixed distribution coefficient, and establishing a hybrid system model for feeder power coordinated control; if being a rolling distribution coefficient, an exchange power P(t) of the control region at time t being obtained, generating a distribution coefficient matrix W(t), and establishing the hybrid system model of the said feeder power coordinated control; confirming a control objective function min J, converting it into a MIQP, obtaining a full period control quantity; selecting a first control quantity P of the optimized control sequence, sending the first control quantity P to the control device.

Abstract: A use of an intervertebral disc fibrosis-inducing substance in preparation of medication, where the medication is used for the treatment of degenerative spinal diseases. The inventors of the present disclosure make use of the pro-fibrotic effect of the intervertebral disc fibrosis-inducing substance and the auxiliary effect of the fibroblast to achieve further treatment of intervertebral disc degeneration. The simultaneous administration of the above two drugs can reasonably control the degeneration and achieve the purpose of stepped treatment, thereby having clinical transformation value. In addition, the therapy combining the intervertebral disc fibrosis-inducing substance with the cell in the present disclosure allows the treatment regimen more personalized.

Abstract: A turbine blade includes a blade body, a division plate, a plurality of first protruding ridges, a plurality of second protruding ridges, a first jet hole group, and a second jet hole group. The blade body includes a suction-side wall surface and a pressure-side wall surface, which are provided with multiple film cooling holes. The stagnation region at the leading edge of the blade body is provided with multiple film cooling holes. The first and second jet hole groups are provided on the division plate. The first protruding ridges are provided on a suction-side inner wall surface, and the second ridges are provided on a pressure-side inner wall surface. An engine including the turbine blade is further provided.

Abstract: A robotic system includes a support structure, a motor mount assembly, first and second parallel chains, a serial translation assembly, a sensor and a control module. The motor mount assembly includes rotary motors, where the rotary motors include a first rotary motor and a second rotary motor. The first and second parallel chains are connected to the movable platform, the rotary motors and the motor mount assembly. The serial translation assembly is connected to the supporting structure and the motor mount assembly and includes a linear actuator and a third rotary motor. The sensor is connected to the movable platform and detects force applied by a human operator on the movable platform and generates a signal indicative of the force applied. The control module controls the rotary motors and the third rotary motor based on the signal to assist the human operator in moving the movable platform.

Abstract: The present invention provides a high-precision identification method and system for substations, including building a Mask RCNN objection recognition network model based on convolutional neural networks; inputting acquired image information of a object into the Mask RCNN object recognition network model for preliminary recognition and outputting a recognition result of the object; using an information entropy to create a semantic decision tree and correcting the recognition result of the object according to a principle of relative correlation between different objects and outputting a final recognition decision result; reading the recognition decision result to obtain a true type of the object to be recognized. The present invention greatly improves the accuracy of image recognition of substations, and has a positive role in the research and development of automatic inspection equipment for inspection robots.

Abstract: The present invention relates to the field of hemodialysis and peritoneal dialysis, in particular to a fat emulsion dialysate, and preparation method and the use thereof. Provided in the present invention is a fat emulsion dialysate, comprising a long-chain fat emulsion oil, a medium-chain triglyceride, an anti-oxidant, sodium oleate, glycerin, phospholipid, and a solvent. Compared with traditional dialysis, the fat emulsion dialysate provided by the present invention has a better advantage for protein-bound toxin removal. In addition, the fat emulsion dialysate not only has a simple preparation method and a low cost, but also has good stability and safety, and remains stable at room temperature for 14 days without obvious precipitation. Thus, the fat emulsion dialysate can become a hemodialysis dialysate or peritoneal dialysate with broad application prospects, and has good industrialization prospects.

Abstract: A method for fabricating a second generation high-temperature superconductor (2G-HTS) tape, including: (S1) depositing a superconducting thin film on a surface of a ductile metal substrate with a buffer layer; (S2) forming a micro-holes array pattern on a surface of the superconducting thin film by etching using a reel-to-reel dynamic femtosecond infrared laser etching system, where the micro-holes array pattern covers the superconducting thin film; (S3) depositing a superconducting thick film on the surface of the superconducting thin film; and (S4) depositing a silver protective layer and a copper stabilization layer on a surface of the superconducting thick film.

Abstract: A robotic system includes a support structure, a platform, a center serial chain, outer serial chains, motors, a sensor, and a control module. The center serial chain connects a center of the platform to the support structure and includes first joints connected to a linear sliding shaft. The outer serial chains are disposed radially outward of the center serial chain. Each of the outer serial chains includes second joints connecting a bar to the platform and the supporting structure. The motors are connected to the outer serial chains. The sensor is connected to the platform and detects at least one of force or torque applied by a human operator on the platform and generates a signal indicative thereof. The control module controls the motors based on the signal to assist the human operator in at least one of moving or rotating the platform.

Abstract: The present disclosure provide a method for identifying power equipment targets based on human-level concept learning, including: creating a dataset of power equipment images, and annotating power equipment in power equipment images; training neural network and Bayesian network with the annotated dataset and respectively acquire identification results and conditional probabilities; calculating probabilities of unions with the conditional probabilities; and filtering the identification result corresponding to the highest probability of the union as identification result of the dataset of the power equipment images and complete the identification of the power equipment. The present disclosure combines Mask R-CNN and probabilistic graphical model. The bottom layer uses Mask R-CNN, and the top layer uses Bayesian network to train in identifying power equipment images, so that a small amount of data samples can achieve good recognition, which improved the performance of Mask R-CNN model.

Abstract: An intelligent mouth opening rehabilitation device is provided, including: a body, an end of the body is provided with an upper bite pad and a lower bite pad; a pressure sensor, for detecting pressure data on the upper bite pad and/or the lower bite pad; a stepping motor, for driving the upper bite pad and/or the lower bite pad to swing longitudinally; and a processor, for controlling the stepping motor to operate or stop according to the pressure data and/or a preset training instruction, thereby driving the upper bite pad and/or the lower bite pad to swing longitudinally or to stop. Compared with traditional mouth opening rehabilitation devices, the intelligent mouth opening rehabilitation device controls automatically the upper bite pad and/or the lower bite pad to swing longitudinally, so that a mouth opening training is more accurate, and more controllable. Therefore, a rehabilitation effect is greatly improved.

Abstract: An oral colon-targeted delivery system is described, which includes a bacterial flora sensitive layer which contains polysaccharides and covers the exterior of active ingredients, a pH sensitive layer which contains any polymer composition dissolved under the condition of pH?7 and covers the exterior of the bacterial flora sensitive layer. A preparation method and applications of the delivery system are also described. According to the oral colon-targeted delivery system combined with the pH sensitive and bacterial flora sensitive mechanisms, the selective dissolution and release of active ingredients in the colon site are effectively improved by using double-layer protection so that the therapeutic or diagnostic effect is enhanced, and the application prospect is broad.

Abstract: An injectable in situ pore-forming hydrogel system and its preparation method and use are provided. The injectable in situ pore-forming hydrogel system uses an injectable hydrogel as a continuous base phase, and isolated live cells and magnesium particles are distributed in the continuous base phase, where the injectable hydrogel is a precursor or prepolymer of hydrogel, which can form hydrogel by cross-linking. The injectable in situ pore-forming hydrogel system can be used to create pores while the gel encapsulates live cells, which makes use of both the injectability and porous structures of hydrogel, which is important for the repair of cavitary, surgically difficult and irregularly defective tissues; meanwhile, magnesium particles generate magnesium ions after the former undergoes gas production and degradation, which can improve the bioactivity of the gel and aid in tissue repair.

Abstract: This invention relates to a double-layer fibrous annulus patch, a patch clamp, a suture needle and a fishbone suture. The inner layer foldable patch and the outer layer foldable patch are arranged and connected by a pair of crossed flexible connectors. Both ends of the two patches are connected by auxiliary connectors. A pair of auxiliary connectors are further arranged on both sides of the outer foldable patch, which can be used with the patch clamp to unfold the patch and secure it in place. With both patches in a folded state, the patch clamp is used to push the inner foldable patch through the rupture in the intervertebral disc into the annulus fibrosus and the patch unfolds within the annulus fibrosus. The outer layer foldable patch is unfolded on the outside of the annulus fibrosus and is fixed by two auxiliary connectors and fishbone sutures.

Abstract: A method for catalytic asymmetric synthesis of a phosphorus-stereogenic (P-stereogenic) nucleoside derivative of formula (3) and a catalyst used therein. The P-stereogenic nucleoside derivative (3) can be hydrolyzed to obtain remdesivir.

Abstract: A robotic system includes a support structure, a motor mount assembly, first and second parallel chains, a serial translation assembly, a sensor and a control module. The motor mount assembly includes rotary motors, where the rotary motors include a first rotary motor and a second rotary motor. The first and second parallel chains are connected to the movable platform, the rotary motors and the motor mount assembly. The serial translation assembly is connected to the supporting structure and the motor mount assembly and includes a linear actuator and a third rotary motor. The sensor is connected to the movable platform and detects force applied by a human operator on the movable platform and generates a signal indicative of the force applied. The control module controls the rotary motors and the third rotary motor based on the signal to assist the human operator in moving the movable platform.