Patents Assigned to Shanghai Jiaotong University
  • Patent number: 11440793
    Abstract: Described herein is a hydrogen sensor on medium or low temperature solid micro heating platform, comprising: a substrate; a thermal-insulating layer disposed above the substrate; a heating structure disposed above the thermal-insulating layer, and thermally and electrically isolated from the substrate by the thermal-insulating layer; a thermal-conducting layer covering the heating structure; and a sensitive layer disposed on the thermal-conducting layer. The sensitive layer can be heated to a set temperature by the heating structure to improve sensitivity and reduce the response time.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: September 13, 2022
    Assignee: Shanghai Jiaotong University
    Inventors: Guifu Ding, Qi Liu, Yan Wang, Yunna Sun
  • Patent number: 11415494
    Abstract: A method of rapidly and completely rendering a tissue (11) rich in lipid droplets (12) transparent. The method comprises the following steps: providing a tissue sample (11) rich in lipid droplets (12) and immobilized with a hydrogel; performing a pre-transparency-rendering process on the tissue sample (11) to obtain a pre-processed sample; performing a transparency-rendering process on the pre-processed sample to obtain a transparency-rendered sample; and performing a post-transparency-rendering process on the transparency-rendered sample to obtain a final transparency-rendered sample (31). The method does not damage the fine structure of a biological tissue (11) and can significantly increase a depth of an optical image of the biological tissue (11). The method does not damage the fine structure of a biological tissue (11) and can significantly increase a depth of an optical image of the biological tissue (11).
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: August 16, 2022
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Xiaowei Li, Zhifeng Shao, Mengjie Lai, Jun Li, Daniel Czajkowsky
  • Publication number: 20220233358
    Abstract: The present invention relates to the field of medical devices, and relates to an electrophysiological test method for an auditory brainstem implant (ABI) and a recording electrode used therein. According to the method of the present invention, there is no need to subcutaneously place an additional recording electrode for a patient, which simplifies preoperative preparation. Moreover, the method has advantages of a high signal-to-noise ratio, a fast response speed, a short recording time, and a large anti-interference ability, thus can effectively improve efficiency of intraoperative electrode test. The method is suitable for use in an auditory brainstem implantation surgery. Besides, the present invention enables the auditory brainstem implantation to be located more accurately, thereby expanding a scope of application.
    Type: Application
    Filed: June 12, 2020
    Publication date: July 28, 2022
    Applicant: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
    Inventors: Hao WU, Huan JIA, Ying CHEN
  • Publication number: 20220220069
    Abstract: Disclosed by the present invention are an SIRT6 small-molecule allosteric activator and the application thereof and provided is an SIRT6 small-molecule allosteric activator that contains a derivative as shown in formula (1) or a pharmacologically acceptable salt thereof as the active ingredient. The SIRT6 small-molecule allosteric activator designed and synthesized in the present invention has high efficacy and low toxicity, may significantly activate SIRT6 activity during in vitro experiments, and has great importance in the development of pharmaceuticals for relevant diseases.
    Type: Application
    Filed: May 14, 2018
    Publication date: July 14, 2022
    Applicant: SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Jian ZHANG, Yinyi CHEN, Cong RUAN, Xiuyan YANG, Chengxiang WANG, Qiufen ZHANG, Jialin SHANG, Xinyuan XU
  • Patent number: 11366185
    Abstract: An online automatic measurement system for a claw-pole overall magnetic property comprising: a feeding part, a claw-pole overall magnetic property measurement unit, and a discharging part disposed in sequence, and a robotic arm disposed there among. The robotic arm receives an operation instruction output by a control unit to grab claw poles to be measured in sequence and removes measured claw poles on the claw-pole overall magnetic property measurement unit. The claw-pole overall magnetic property measurement unit outputs a control power supply to the claw-pole overall magnetic property measurement unit according to the instruction of the control unit, receives an induction current of the measured claw poles, and output a measurement result to the control unit.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: June 21, 2022
    Assignees: JIANGSU LONGCHENG PRECISION FORGING GROUP CO., LTD., SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Xiaofeng Tang, Chengliang Hu, Minjun Tang, Li Zhu, Jinsheng Cheng, Zhen Zhao
  • Patent number: 11368114
    Abstract: The invention provides an adaptive inertial control method based on IIDG (Inverter Interfaced Distributed Generator) of a virtual synchronous motor. By building an adaptive virtual inertia and IIDG output frequency model, the adaptive control sensitive factor is selected from a model according to the virtual synchronous motor dynamic response features; the adaptive inertial upper and lower limits are selected from a model according to the energy storage configuration constraint; the IIDG optimization control strategy is obtained. The control on the grid-connected inverter distributive power supply can be realized, so that the IIDG output is more stable; the interference on the system can be well handled; meanwhile, the characteristics of small overshoot and fast response are realized; the ultra-high dynamic features are realized.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: June 21, 2022
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Wentao Huang, Meiyi Li, Nengling Tai, Xiaodong Zheng
  • Publication number: 20220088202
    Abstract: Disclosed are a nucleic acid-drug conjugate based on a phosphorothioate-modified nucleic acid, a drug delivery system, and a preparation method therefor. The nucleic acid-drug conjugate is formed by reacting and conjugating a phosphorothioate group in a phosphorothioate-modified nucleic acid with a group that is modified on a drug molecule and able to undergo electrophilic reaction with the phosphorothioate groups; in addition, by selecting different nucleic acid sequences including functional nucleic acids, the nucleic acid-drug conjugate is able to be self-assembled into various forms of drug-containing nano-carriers for drug delivery.
    Type: Application
    Filed: January 23, 2019
    Publication date: March 24, 2022
    Applicant: Shanghai Jiaotong University
    Inventors: Chuan Zhang, Jiao Zhang, Yuanyuan Guo
  • Publication number: 20210322137
    Abstract: Disclosed is a dental implant distractor, comprising an implant module and a traction module. The implant module comprises an implant, a sealing screw, and a base body. The traction module comprises a connecting screw rod, a traction screw rod, an inner sleeve, and an outer sleeve; the connecting screw rod is threadedly connected to the base body; the traction screw rod is located below the connecting screw rod; the inner sleeve is provided below the base body. This apparatus can automatically complete the installation of the base body and the sealing of the connecting screw rod after traction is completed; since the installation of the base body and the sealing do not need to be performed again, operation steps are simplified, the clinical operation difficulty is reduced, and the problem of slippage of an upper bone section to the original position is avoided.
    Type: Application
    Filed: December 27, 2017
    Publication date: October 21, 2021
    Applicants: SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE, SHANGHAI JINGTANG MEDICAL APPARATUS AND INSTRUMENTS LIMITED
    Inventors: Chenping ZHANG, Jiannan LIU, Fuming XU, Xingzhou QU, Jizhuang MA
  • Patent number: 11137353
    Abstract: Provided are a metallic micro/nano-structure and an optical fiber having it on the end-facet. The metallic micro/nano-structure comprises of a metallic film and a micro/nano pattern in the metallic film. The micro/nano pattern divides the metallic film into a periodic structure and an embedded defect structure; the defect structure locally breaks the periodicity of the periodic structure; in at least one dimension, the periodic structure has a period T satisfying 0.75?<T<1.25?, ? is a wavelength of a surface plasmon at an interface between the metallic film and a medium; and the surface plasmon resonates within the defect structure and its surrounding area. The optical fiber end-facet device takes the advantages of single-mode optical fiber systems, including stable optical transmission, compact systems and flexible configurations.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: October 5, 2021
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Tian Yang, Zeyu Lei
  • Patent number: 11132815
    Abstract: A system and method for retrieving a blood vessel corresponding positional relation under multi-angle angiography. The system includes an angiography machine, an angiographic image receiving module, a center point calibration module, a corresponding feature point detection module, and a feature point corresponding blood vessel module. The angiography machine is used for performing angiography and collecting angiographic images of multiple projection body positions. The angiographic image receiving module is used for receiving an angiographic image and transmitting the angiographic image to the center point calibration module. The center point calibration module is used for calibrating a center point offset caused by the multi-angle angiography system and transmitting the result to the feature point detection module.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: September 28, 2021
    Assignee: Shanghai Jiaotong University
    Inventors: Shengxian Tu, Lulu Yang, Junqing Yang, Su Zhang
  • Publication number: 20210207115
    Abstract: Methods of preparing and using a highly active blood coagulation factor XI mutant and a gene therapy/editing vector thereof and a recombinant/fusion protein thereof. The nucleotide sequence of the mutant is as shown in SEQ ID NOs: 1-6, and the amino acid sequence is as shown in SEQ ID NO: 7.
    Type: Application
    Filed: August 30, 2018
    Publication date: July 8, 2021
    Applicants: RUIJIN HOSPITAL SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Xuefeng WANG, Wenman WU, Qiulan DING
  • Patent number: 10995142
    Abstract: Provided in the present invention are a monoclonal antibody FnAb8 and application thereof.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: May 4, 2021
    Assignee: Shanghai Jiaotong University
    Inventors: Yuhong Xu, Yangsheng Qiu
  • Patent number: 10989587
    Abstract: A distributed fibre sensing system and a vibration detection and positioning method therefor are disclosed. The system comprises: a signal generating module, a light source module, an optical frequency comb generating module, a frequency sweeping and pulse generating module, an optical circulator, a sensing fibre, an interference module, a photoelectric conversion module and a detection and position module. The method comprises: obtaining a plurality of Rayleigh backscattering signals of the sensing fibre; performing a fading elimination processing on the Rayleigh backscattering signals, thereby obtaining a plurality of averaged Rayleigh backscattering signals of non-interference fading and polarization fading; performing a phase processing on the averaged Rayleigh backscattering signals, thereby obtaining phase variance curves; and determining a vibration point according to variances in the phase variance curves, and finally obtaining a position and a vibration waveform of the vibration point.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: April 27, 2021
    Assignees: SHANGHAI JIAOTONG UNIVERSITY, NEUBREX CO., LTD.
    Inventors: Zuyuan He, Qingwen Liu, Dian Chen, Xinyu Fan
  • Patent number: 10975356
    Abstract: Provided is a method for obtaining female germline stem cells from follicular aspirates.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: April 13, 2021
    Assignee: Shanghai Jiaotong University
    Inventor: Ji Wu
  • Patent number: 10922140
    Abstract: Physical Graphics Processing Unit (GPU) resource scheduling system and method between virtual machines are provided. An agent is inserted between a physical GPU instruction dispatch and a physical GPU interface through a hooking method, for delaying sending instructions and data in the physical GPU instruction dispatch to the physical GPU interface, monitoring a set of GPU conditions of a guest application executing in the virtual machine and a use condition of physical GPU hardware resources, and then providing a feedback to a GPU resource scheduling algorithm based on time or a time sequence. With the agent, it is unneeded for the method to make any modification to the guest application of the virtual machine, a host operating system, a virtual machine operating system, a GPU driver and a virtual machine manager.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: February 16, 2021
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Miao Yu, Zhengwei Qi, Haibing Guan, Yin Wang
  • Patent number: 10913657
    Abstract: The present invention belongs to the field of new materials technology and discloses a green method for preparing functionalized carbon materials. The present invention can use potassium ferrate(VI) as an oxidant and mechanical milling as a reaction technique for oxidizing carbon materials in a preparation of functionalized carbon materials having oxygen-containing functional groups. Compared with the prior art, the present invention provides a method that combines an environmentally friendly oxidant with an environmentally friendly reaction process. The oxidant potassium ferrate(VI) is a green oxidant without producing any toxic byproducts. The reaction process is solvent-free, facilitated by milling the solid mixture of carbon materials and the oxidant. Thus, the present invention provides an environmentally friendly method for preparing oxidatively functionalized carbon materials, which is of promotion value.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: February 9, 2021
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Tao Li, Zhaoyang Zhang, Ying Zhou
  • Publication number: 20200367971
    Abstract: The present application relates to computer-based preoperative planning technology, and discloses a preoperative planning method for multimodal ablation treatment and apparatus thereof, which can automatically provide objective, scientific, and quantitative multimodal ablation planning information. In this method, acquiring parameters of an volume to be ablated; calculating property changes of the tissue caused by performing freezing on the volume according to the parameters of the volume to be ablated, and acquiring a first planning data required for the property changes of the tissue to satisfy a first predetermined condition; further calculating property changes of the tissue caused by performing heating on the volume to acquire a second planning data required for the property changes of the tissue to satisfy a second predetermined condition based on the properties satisfying the first predetermined condition; outputting the first planning data and the second planning data.
    Type: Application
    Filed: January 29, 2019
    Publication date: November 26, 2020
    Applicant: Shanghai Jiaotong University
    Inventors: Xuemin XU, Aili ZHANG, Jianqi SUN, Ping LIU, Wentao LI
  • Publication number: 20200239300
    Abstract: Described herein is a hydrogen sensor on medium or low temperature solid micro heating platform, comprising: a substrate; a thermal-insulating layer disposed above the substrate; a heating structure disposed above the thermal-insulating layer, and thermally and electrically isolated from the substrate by the thermal-insulating layer; a thermal-conducting layer covering the heating structure; and a sensitive layer disposed on the thermal-conducting layer. The sensitive layer can be heated to a set temperature by the heating structure to improve sensitivity and reduce the response time.
    Type: Application
    Filed: December 24, 2019
    Publication date: July 30, 2020
    Applicant: Shanghai Jiaotong University
    Inventors: Guifu Ding, Qi Liu, Yan Wang, Yunna Sun
  • Publication number: 20200238614
    Abstract: The present disclosure relates to an apparatus and a method for high-precision three-dimensional printing using a salt solution. The apparatus includes a receiving platform system and a printing device. The receiving platform system includes a conductivity cell, a high-voltage electrostatic generation system, a printing platform, and a printing platform driver. The conductivity cell contains salt solution. The high-voltage electrostatic generating system is connected with the conductivity cell. The printing platform is disposed in the salt solution in the conductivity cell. The printing platform driver is connected with the printing platform to drive the printing platform to move along a Z?-axis perpendicular to a horizontal direction. The printing device prints a product on the printing platform. The apparatus is convenient to operate, and solves the problems of low resolution of biological 3D printing, limited product height, and difficulty in using multiple printing methods in combination.
    Type: Application
    Filed: January 21, 2020
    Publication date: July 30, 2020
    Applicant: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
    Inventors: Zhiguang QIAO, Xing ZHANG, Yongqiang HAO, Yu HAN, Binbin SUN, Chunbin LI, Meifei LIAN, Wenbo JIANG, Kerong DAI
  • Patent number: 10695821
    Abstract: A rivet rotational feeding method for friction self-piercing riveting (F-SPR) system, comprising: a semi-hollow rivet, a driving spindle and a die. The bottom surface of the rivet head is connected to the semi-hollow rivet shank. The semi-hollow rivet shank has a wedge-shaped end. The rivet head has rotation driving structures and positioning structure on the top end. The rotation driving structures are central symmetric concave or convex surfaces. The positioning structure is a central symmetric and mirror symmetric concave or convex surface. The matching between the driving spindle and the rivet can improve the rotation reliability and positioning accuracy of the riveting at a high rotational speed during F-SPR process, which is beneficial to solve the problems of poor stability and non-coincidence between the geometry axis and the rotation axis of the rivet.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: June 30, 2020
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Yongbing Li, Yunwu Ma, Ming Lou, Zhongqin Lin