Patents Assigned to Shanghai Jiaotong University
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Publication number: 20230398071Abstract: The present invention relates to the field of hemodialysis and peritoneal dialysis, in particular to a fat emulsion dialysate, and preparation method and the use thereof. Provided in the present invention is a fat emulsion dialysate, comprising a long-chain fat emulsion oil, a medium-chain triglyceride, an anti-oxidant, sodium oleate, glycerin, phospholipid, and a solvent. Compared with traditional dialysis, the fat emulsion dialysate provided by the present invention has a better advantage for protein-bound toxin removal. In addition, the fat emulsion dialysate not only has a simple preparation method and a low cost, but also has good stability and safety, and remains stable at room temperature for 14 days without obvious precipitation. Thus, the fat emulsion dialysate can become a hemodialysis dialysate or peritoneal dialysate with broad application prospects, and has good industrialization prospects.Type: ApplicationFiled: July 5, 2023Publication date: December 14, 2023Applicant: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of MedicineInventors: Feng DING, Yifeng WANG, Yuqi SHEN, Jiaolun LI
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Patent number: 11844289Abstract: A method for fabricating a second generation high-temperature superconductor (2G-HTS) tape, including: (S1) depositing a superconducting thin film on a surface of a ductile metal substrate with a buffer layer; (S2) forming a micro-holes array pattern on a surface of the superconducting thin film by etching using a reel-to-reel dynamic femtosecond infrared laser etching system, where the micro-holes array pattern covers the superconducting thin film; (S3) depositing a superconducting thick film on the surface of the superconducting thin film; and (S4) depositing a silver protective layer and a copper stabilization layer on a surface of the superconducting thick film.Type: GrantFiled: January 14, 2023Date of Patent: December 12, 2023Assignee: Shanghai Jiaotong UniversityInventors: Yue Zhao, Chunjiang Guo, Yue Wu, Sikan Chen, Jiamin Zhu, Wei Wu, Zhijian Jin
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Patent number: 11813743Abstract: A robotic system includes a support structure, a platform, a center serial chain, outer serial chains, motors, a sensor, and a control module. The center serial chain connects a center of the platform to the support structure and includes first joints connected to a linear sliding shaft. The outer serial chains are disposed radially outward of the center serial chain. Each of the outer serial chains includes second joints connecting a bar to the platform and the supporting structure. The motors are connected to the outer serial chains. The sensor is connected to the platform and detects at least one of force or torque applied by a human operator on the platform and generates a signal indicative thereof. The control module controls the motors based on the signal to assist the human operator in at least one of moving or rotating the platform.Type: GrantFiled: December 17, 2021Date of Patent: November 14, 2023Assignees: GM GLOBAL TECHNOLOGY OPERATIONS LLC, Shanghai JiaoTong UniversityInventors: Qiao Sun, Xianbao Chen, Jing Sun, Dalong Gao, Feng Gao, Ningjian Huang
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Patent number: 11810348Abstract: The present disclosure provide a method for identifying power equipment targets based on human-level concept learning, including: creating a dataset of power equipment images, and annotating power equipment in power equipment images; training neural network and Bayesian network with the annotated dataset and respectively acquire identification results and conditional probabilities; calculating probabilities of unions with the conditional probabilities; and filtering the identification result corresponding to the highest probability of the union as identification result of the dataset of the power equipment images and complete the identification of the power equipment. The present disclosure combines Mask R-CNN and probabilistic graphical model. The bottom layer uses Mask R-CNN, and the top layer uses Bayesian network to train in identifying power equipment images, so that a small amount of data samples can achieve good recognition, which improved the performance of Mask R-CNN model.Type: GrantFiled: March 24, 2021Date of Patent: November 7, 2023Assignee: Shanghai Jiaotong UniversityInventors: Yadong Liu, Yingjie Yan, Siheng Xiong, Ling Pei, Zhe Li, Peng Xu, Lei Su, Xiaofei Fu, Xiuchen Jiang
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Patent number: 11808980Abstract: A compact silicon waveguide mode converter, a dielectric meta-surface structure based on periodical oblique subwavelength perturbations, including a top silicon structure with oblique subwavelength perturbations etched in certain periods with period length of ?, a duty cycle and an oblique angle ? on the SOI substrate. The invention adopts an all-dielectric meta-surface structure with oblique subwavelength perturbation, which can achieve a compact mode conversion from fundamental mode to arbitrary high-order mode of silicon waveguide, and can improve the optical communication capacity greatly.Type: GrantFiled: June 25, 2019Date of Patent: November 7, 2023Assignee: SHANGHAI JIAOTONG UNIVERSITYInventors: Hongwei Wang, Yong Zhang, Yu He, Lu Sun, Yikai Su
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Publication number: 20230338479Abstract: A high-activity blood coagulation factor XI mutant Ala570Thr (A570T), having nucleotide sequences as shown in SEQ ID NOs: 1-4 and an amino acid sequence as shown in SEQ ID NO: 5, is provided. The mutant is resistant to a physiological inhibitor thereof after being activated from a zymogen state to an active enzyme. Therefore, the mutant has a very high blood coagulation activity and a stronger catalytic ability for a non-physiological substrate; and the mutant is applied to the treatment of hemorrhagic diseases, and has good prospects in terms of gene therapy, gene editing and recombinant protein replacement treatments.Type: ApplicationFiled: April 13, 2021Publication date: October 26, 2023Applicants: RUIJIN HOSPITAL SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINEInventors: Wenman WU, Xuefeng WANG, Qiulan DING
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Publication number: 20230338219Abstract: An intelligent mouth opening rehabilitation device is provided, including: a body, an end of the body is provided with an upper bite pad and a lower bite pad; a pressure sensor, for detecting pressure data on the upper bite pad and/or the lower bite pad; a stepping motor, for driving the upper bite pad and/or the lower bite pad to swing longitudinally; and a processor, for controlling the stepping motor to operate or stop according to the pressure data and/or a preset training instruction, thereby driving the upper bite pad and/or the lower bite pad to swing longitudinally or to stop. Compared with traditional mouth opening rehabilitation devices, the intelligent mouth opening rehabilitation device controls automatically the upper bite pad and/or the lower bite pad to swing longitudinally, so that a mouth opening training is more accurate, and more controllable. Therefore, a rehabilitation effect is greatly improved.Type: ApplicationFiled: July 27, 2021Publication date: October 26, 2023Applicant: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of MedicineInventors: Jiannan LIU, Guangtao ZHAI, Chenping ZHANG, Zhiyuan ZHANG
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Patent number: 11784685Abstract: A THz UM-MIMO channel estimation method based on the DCNN comprises the steps: the hybrid spherical and planar-wave modeling (HSPM), by taking a sub-array in the antenna array as a unit, employing the PWM within the sub-array, and employing the SWM among the sub-arrays; estimating the channel parameters between the reference sub-arrays at Tx and Rx through a DCNN, including the angles of departure and arrival, the propagation distance and the path gain; deducing the channel parameters between the reference sub-array and other sub-arrays by utilizing the obtained channel parameters and the geometrical relationships among sub-arrays, and recovering the channel matrix; wherein accurate three-dimensional channel modeling is achieved by the HSPM, which possesses high modeling accuracy and low complexity.Type: GrantFiled: June 16, 2022Date of Patent: October 10, 2023Assignee: SHANGHAI JIAOTONG UNIVERSITYInventors: Chong Han, Yuhang Chen, Longfei Yan
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Patent number: 11771805Abstract: An injectable in situ pore-forming hydrogel system and its preparation method and use are provided. The injectable in situ pore-forming hydrogel system uses an injectable hydrogel as a continuous base phase, and isolated live cells and magnesium particles are distributed in the continuous base phase, where the injectable hydrogel is a precursor or prepolymer of hydrogel, which can form hydrogel by cross-linking. The injectable in situ pore-forming hydrogel system can be used to create pores while the gel encapsulates live cells, which makes use of both the injectability and porous structures of hydrogel, which is important for the repair of cavitary, surgically difficult and irregularly defective tissues; meanwhile, magnesium particles generate magnesium ions after the former undergoes gas production and degradation, which can improve the bioactivity of the gel and aid in tissue repair.Type: GrantFiled: July 7, 2020Date of Patent: October 3, 2023Assignee: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of MedicineInventors: Xinquan Jiang, Wenjie Zhang, Yanmei Tang, Sihan Lin
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Patent number: 11771656Abstract: An oral colon-targeted delivery system is described, which includes a bacterial flora sensitive layer which contains polysaccharides and covers the exterior of active ingredients, a pH sensitive layer which contains any polymer composition dissolved under the condition of pH?7 and covers the exterior of the bacterial flora sensitive layer. A preparation method and applications of the delivery system are also described. According to the oral colon-targeted delivery system combined with the pH sensitive and bacterial flora sensitive mechanisms, the selective dissolution and release of active ingredients in the colon site are effectively improved by using double-layer protection so that the therapeutic or diagnostic effect is enhanced, and the application prospect is broad.Type: GrantFiled: November 17, 2016Date of Patent: October 3, 2023Assignee: Shanghai Jiaotong University School of MedicineInventors: Zeyu Xiao, Lei Lu, Gaoxian Chen, Miao Lin
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Patent number: 11759347Abstract: An apparatus used for increasing the level of CD4+T cells in a mammal. The mammal has a cancerous tissue. The apparatus comprises a cold treatment unit and a heat treatment unit. The cold treatment unit is used for cooling the cancerous tissue. The heat treatment unit is used for heating the cancerous tissue. A method for increasing the level of CD4+ T cells in the body of a cancer patient, comprising steps for cold treatment of the cancerous tissue and for heat treatment of the cancerous tissue.Type: GrantFiled: July 6, 2015Date of Patent: September 19, 2023Assignee: SHANGHAI JIAOTONG UNIVERSITYInventors: Xuemin Xu, Aili Zhang, Ping Liu, Jingfeng Bai, Jianqi Sun
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Patent number: 11707778Abstract: A method and apparatus for manufacturing an equiaxed crystal aluminum alloy cast ingot by using additive manufacturing and rapid solidification techniques are provided. The apparatus comprises: a metal heating mechanism and a negative pressure cooling mechanism. The metal heating mechanism is located above the negative pressure cooling mechanism and is connected thereto by a nozzle. The negative pressure cooling mechanism comprises a vacuum chamber having an air inlet hole and an air outlet hole, and a three-dimensional moving ingot mechanism disposed inside the vacuum chamber. The three-dimensional moving ingot mechanism comprises a moving ingot and a two-dimensional moving platform vertically connected to the moving ingot. A water cooling mechanism is disposed outside the moving ingot, and the moving ingot is driven by a precision motor to precisely move up and down.Type: GrantFiled: November 7, 2018Date of Patent: July 25, 2023Assignee: SHANGHAI JIAOTONG UNIVERSITYInventors: Jiao Zhang, Baode Sun, Qing Dong
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Publication number: 20230210672Abstract: This invention relates to a double-layer fibrous annulus patch, a patch clamp, a suture needle and a fishbone suture. The inner layer foldable patch and the outer layer foldable patch are arranged and connected by a pair of crossed flexible connectors. Both ends of the two patches are connected by auxiliary connectors. A pair of auxiliary connectors are further arranged on both sides of the outer foldable patch, which can be used with the patch clamp to unfold the patch and secure it in place. With both patches in a folded state, the patch clamp is used to push the inner foldable patch through the rupture in the intervertebral disc into the annulus fibrosus and the patch unfolds within the annulus fibrosus. The outer layer foldable patch is unfolded on the outside of the annulus fibrosus and is fixed by two auxiliary connectors and fishbone sutures.Type: ApplicationFiled: September 23, 2022Publication date: July 6, 2023Applicant: Shanghai Jiaotong UniversityInventors: Maodan NIE, Chengkung CHENG
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Patent number: 11671300Abstract: A discrete Fourier transform spread orthogonal time frequency space modulation method comprises the steps of performing DFT preceding processing and delay-Doppler domain mapping processing on the transmit data symbols, OTFS modulator, and performing delay-Doppler domain demapping processing and IDFT decoding processing on a received signal to realize demodulation; compared with the existing waveforms, including OFDM and DFT-s-OFDM, the proposed DFT-s-OTFS can reduce the bit error rate under high Doppler spread and the peak-to-average power ratio of the transmitted signal at the same time.Type: GrantFiled: June 16, 2022Date of Patent: June 6, 2023Assignee: SHANGHAI JIAOTONG UNIVERSITYInventors: Chong Han, Yongzhi Wu
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Patent number: 11655255Abstract: A method for catalytic asymmetric synthesis of a phosphorus-stereogenic (P-stereogenic) nucleoside derivative of formula (3) and a catalyst used therein. The P-stereogenic nucleoside derivative (3) can be hydrolyzed to obtain remdesivir.Type: GrantFiled: October 17, 2022Date of Patent: May 23, 2023Assignees: SPH NO.1 BIOCHEMICAL & PHARMACEUTICAL CO., LTD., Shanghai Jiaotong UniversityInventors: Wanbin Zhang, Mo Wang, Lu Zhang, Xiaohong Huo, Zhenfeng Zhang, Qianjia Yuan, Jianzhong Chen
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Publication number: 20230150118Abstract: A robotic system includes a support structure, a motor mount assembly, first and second parallel chains, a serial translation assembly, a sensor and a control module. The motor mount assembly includes rotary motors, where the rotary motors include a first rotary motor and a second rotary motor. The first and second parallel chains are connected to the movable platform, the rotary motors and the motor mount assembly. The serial translation assembly is connected to the supporting structure and the motor mount assembly and includes a linear actuator and a third rotary motor. The sensor is connected to the movable platform and detects force applied by a human operator on the movable platform and generates a signal indicative of the force applied. The control module controls the rotary motors and the third rotary motor based on the signal to assist the human operator in moving the movable platform.Type: ApplicationFiled: December 17, 2021Publication date: May 18, 2023Applicant: Shanghai JiaoTong UniversityInventors: Qiao SUN, Xianbao CHEN, Jing SUN, Feng GAO, Dalong GAO, Ningjian HUANG
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Patent number: 11635799Abstract: The invention relates to a nanosecond-scale power resource allocation method and system for microservices. In order to eliminate the macro-control delays, it uses an auto power budgeting module to distribute the limited power resource to each microservice according to its unique power-performance model. On the other side, it deploys an agile power regulation module to bypass the slow power control procedures at the server system layer. By directly invoking the voltage regulation circuit on the processor, this can remove the micro-execution delays. It also leverages a transparent mapping mechanism to coordinate the work of the auto power budgeting module and the agile power regulation module to achieve the optimal allocation of power resources. The present invention can exploit the intra-application variability brought by microservices, thus further break the energy-saving limitation of traditional data centers.Type: GrantFiled: May 19, 2020Date of Patent: April 25, 2023Assignee: SHANGHAI JIAOTONG UNIVERSITYInventors: Chao Li, Xiaofeng Hou, Minyi Guo
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Patent number: 11634808Abstract: The disclosure provides an anti-corrosion conductive film and methods of making and using thereof. The anti-corrosion conductive film is formed by sequentially forming an anti-corrosion protective layer, a stress transition layer and a conducting layer on the surface of a substrate by deposition through a high-low pulse bias alternation method. The anti-corrosion conductive film is a nano-multilayer anti-corrosion conductive film exhibiting excellent corrosion resistance and conductivity. The anti-corrosion conductive film has great application prospects in the fields of metal polar plates of fuel cells, ground grid equipment of power transmission lines, and the like.Type: GrantFiled: January 21, 2019Date of Patent: April 25, 2023Assignee: SHANGHAI JIAOTONG UNIVERSITYInventors: Peiyun Yi, Weixin Zhang, Linfa Peng, Xinmin Lai
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Publication number: 20230031980Abstract: The present disclosure provides methods and kits for diagnosing and assessing SAGE1-positive disorders, and compositions and methods for treating SAGE1-positive disorders. The present disclosure further provides SAGE1 complexes and methods and composition for inhibiting SAGE1 complexes and treating SAGE1-positive disorders.Type: ApplicationFiled: December 14, 2020Publication date: February 2, 2023Applicants: SHANGHAI NINTH PEOPLE'S HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINEInventors: Ming LEI, Wei DENG, Yanjie ZHANG, Yang SONG, Chao ZHENG
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Patent number: 11564755Abstract: The present application provides an automatic knife stop device and a system for fibula cutting, a computer equipment, and a medium. The device includes: an acquisition module; a threshold module; and a judgment module. The present application can avoid the destruction of blood vessels during shaping and greatly improve the success rate of surgery, while greatly improve the robustness of the control system by increasing the strength of the force feedback signal.Type: GrantFiled: July 11, 2022Date of Patent: January 31, 2023Assignee: SHANGHAI NINTH PEOPLE'S HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINEInventors: Jiannan Liu, Junlei Hu, Jing Han, Chenping Zhang, Zilin Wang, Zhiyong Guo, Yige Liu