Patents Assigned to Shanghai Jiaotong University
  • Patent number: 12196792
    Abstract: A non-destructive measurement method and apparatus for the turn-to-turn resistivity distribution (TTRD) in non-insulation (NI) superconducting coils. The method includes: during the discharging or charging process, obtaining experimental values of voltage varying over preset time at different positions of the test coil; dividing the test coil into a plurality of measurement units and obtaining basic circuit elements; then constructing a preset equivalent circuit model including the basic circuit elements; based on the constructed equivalent circuit model, obtaining the first simulated values of voltage varying over preset time at different positions of the test coil; finally, determining the TTRD of the test coil based on the fitness value between experimental values and the first simulated values. When there is high fitness value between the first simulated values and experimental values, the TTRD corresponding to the first simulated values is considered as the TTRD within the test coil.
    Type: Grant
    Filed: May 10, 2024
    Date of Patent: January 14, 2025
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Wei Wu, Li Lu, Jianghong Wan
  • Publication number: 20240390113
    Abstract: A dental braces includes at least one fixing element attached to surfaces of multiple abnormal teeth and provided with a first connector, and an orthodontic element provided with a second connector adapted to the first connector, where the second connector is engaged with the first connector to form an interference fit, such that the orthodontic element is detachably connected to the fixing element; and an elastic force of the orthodontic element acts on the abnormal teeth to control movement of the abnormal teeth.
    Type: Application
    Filed: September 2, 2022
    Publication date: November 28, 2024
    Applicant: SHANGHAI NINTH PEOPLE'S HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Chao LIU, Bing FANG, Qingling YOU
  • Patent number: 12138683
    Abstract: The present invention relates to a substrate-triggered single crystal superalloy directional solidification process, including: (1) preparing a single crystal substrate material having crystallographic characteristics that match crystallographic characteristics of the single crystal superalloy; (2) fabricating a single crystal substrate chilling plate using the obtained single crystal substrate material; and (3) applying the obtained single crystal substrate chilling plate in a directional solidification apparatus, and then preparing a single crystal alloy product by performing superalloy melting and directional solidification.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: November 12, 2024
    Assignee: Shanghai Jiaotong University
    Inventors: Long Zeng, Mingxu Xia, Jun Li, Binqiang Wang, Jianguo Li
  • Patent number: 12142752
    Abstract: Monodisperse microspheres are arranged in macropores of a substrate to form a photonic crystal structure; with the photonic crystal as a template, ordered microporous carbon is synthesized in gaps of the template, and then the photonic crystal template is removed to obtain a three-dimensional ordered hierarchical porous carbon photonic crystal, and thus a large-area thick-film controllable textured photonic crystal is formed and is composited with element sulphur to obtain a sulphur cathode, and the sulphur cathode and metal lithium serving as a counter electrode are assembled into a lithium-sulphur battery. According to the invention, the controllable thick film with an electrode thickness of 10 ?m to 650 ?m can be achieved by changing the thickness of the substrate and the concentration of a suspension liquid. In the meanwhile, large-area preparation with an electrode area of 0.1 cm sup.2 to 400 cm sup.2 can be achieved by changing the area of the substrate.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: November 12, 2024
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Xiaobin Hu, Shengxuan Lin, Zihe Cai, Jlajia Xiao, Yuhang Chen, Yifan Wang
  • Patent number: 12116345
    Abstract: A low-temperature continuous-flow preparation method of bedaquiline includes the following steps. (a) A first feed liquid and a second feed liquid are subjected to a first continuous flow reaction for 30-600 seconds to obtain a first reaction mixture. (b) The first reaction mixture and a third feed liquid are subjected to a second continuous flow reaction for 30-600 seconds to obtain a second reaction mixture. (c) The second reaction mixture was quenched to afford bedaquiline.
    Type: Grant
    Filed: May 21, 2024
    Date of Patent: October 15, 2024
    Assignees: SHANGHAI JIAOTONG UNIVERSITY, SPH NO.1 BIOCHEMICAL & PHARMACEUTICAL CO., LTD.
    Inventors: Wanbin Zhang, Yaohua Zhang, Feng Gao, Wei Yu, Jing Li, Ximing Jiang, Zhenfeng Zhang, Liang Wu, Yuanlin Wang, Yujia Fu
  • Patent number: 12067728
    Abstract: A heterogeneous image registration method includes: performing edge detection on collected images, in combination with a curvature scale space strategy to extract contour curved segments in an edge image. Implementing a feature point detection strategy based on global and local curvature detecting feature points in the contour curved segments, and obtaining the nearest minimum local curvature of the feature points pointing to starting and end points of the contour, respectively. Calculating the number of neighborhood sampling points and neighborhood auxiliary feature points of neighborhoods on both edges of each of the feature points according to the nearest minimum local curvature. Using neighborhood auxiliary feature points and feature points to form a feature triangle, calculating an angle bisector vector and a main direction corresponding to the feature point in the feature triangle.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: August 20, 2024
    Assignee: Shanghai Jiaotong University
    Inventors: Yadong Liu, Yingjie Yan, Qian Jiang, Ling Pei, Zhe Li, Peng Xu, Lei Su, Xiaofei Fu, Xiuchen Jiang
  • Publication number: 20240165037
    Abstract: The invention provides a colonic microbiota responsive polymer characterized in that it is prepared by the polymerization of a response monomer and a linking monomer, wherein the response monomer is a cellobiose with a B-(1,4)-glucoside bond or/and a lactose with a p-galactoside bond; the linking monomer is a monomer that reacts with the hydroxyl group of the response monomer to form an ester or ether directly or by a crosslinking agent. The invention also provides a method for preparation of a colonic microbiota responsive polymer, a degradable film based on the polymer and a preparation method thereof. By means of the characteristics that B-(1,4)-glucoside bond provided by cellobiose or/and p-galactoside bond provided by lactose monomer unit in the polymer can specifically respond to the high abundance of microbiotas (p-glucosidase or/and p-galactosidase) in the colon to specifically degrade in the colon, a colon-targeted delivery system for diagnosis and treatment of colon diseases is constructed.
    Type: Application
    Filed: September 26, 2023
    Publication date: May 23, 2024
    Applicant: Shanghai Jiaotong University School of Medicine
    Inventors: Zeyu Xiao, Gaoxian Chen, Kai Cui
  • Patent number: 11986575
    Abstract: A preparation method of drug-loaded micelles of an absorbable vascular stent coating for angiostenosis in an infant is provided, including the following steps: S1: dissolving a drug to be encapsulated in an appropriate amount of an emulsifying agent, adding a chitosan-poly(p-dioxohone) amphiphilic block copolymer (chitosan-b-PPDO copolymer), and thoroughly mixing to obtain a drug-copolymer solution; S2: adding the drug-copolymer solution obtained in S1 dropwise to an emulsifying agent aqueous solution prepared in advance, and continuously stirring to obtain a stable drug-loaded micellar solution; and S3: removing the emulsifying agent from the micellar solution obtained in S2 through vacuum evaporation, stirring a resulting concentrate, and centrifuging the concentrate to obtain a supernatant; and filtering the supernatant to obtain a filtrate, and subjecting the filtrate to dialysis to obtain the drug-loaded micelles.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: May 21, 2024
    Assignee: XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Kun Sun, Jing Sun, Sun Chen, Kai Bai, Yanan Lu, Lu Wang, Fujun Wang, Fan Zhao, Jihong Huang
  • Patent number: 11973994
    Abstract: Provided is a media processing method. The method is used for uploading a function provided by a user or a third party and obtaining media processing parameters provided by the user. The method includes the following steps: receiving the description information of the media processing and determining whether a function that fulfills the requirement of the description information exists in a system; in a case where the function that fulfills the requirement of the description information exists, selecting the function that fulfills the requirement of the description information from the system; and in a case where the function that fulfills the requirement of the description information does not exist, selecting the function from the system according to the priority or selecting the function that fulfills the requirement of the description information from outside the system.
    Type: Grant
    Filed: July 4, 2020
    Date of Patent: April 30, 2024
    Assignee: Shanghai JiaoTong University
    Inventors: Yiling Xu, Qi Yang, Yunfeng Guan
  • Patent number: 11962153
    Abstract: The present invention provides an active distribution network physics-information fusion control method for a hybrid system model includes an initialization time being a starting time, predicting power output and load of a feeder intermittent distributed power supply within a control time period T, calculating a feeder exchange power deviation variation ?P(t) during the control time period, if being a fixed distribution coefficient, and establishing a hybrid system model for feeder power coordinated control; if being a rolling distribution coefficient, an exchange power P(t) of the control region at time t being obtained, generating a distribution coefficient matrix W(t), and establishing the hybrid system model of the said feeder power coordinated control; confirming a control objective function min J, converting it into a MIQP, obtaining a full period control quantity; selecting a first control quantity P of the optimized control sequence, sending the first control quantity P to the control device.
    Type: Grant
    Filed: October 4, 2021
    Date of Patent: April 16, 2024
    Assignee: Shanghai Jiaotong University
    Inventors: Dong Liu, Fei Chen, Jiaming Weng
  • Publication number: 20240115658
    Abstract: A use of an intervertebral disc fibrosis-inducing substance in preparation of medication, where the medication is used for the treatment of degenerative spinal diseases. The inventors of the present disclosure make use of the pro-fibrotic effect of the intervertebral disc fibrosis-inducing substance and the auxiliary effect of the fibroblast to achieve further treatment of intervertebral disc degeneration. The simultaneous administration of the above two drugs can reasonably control the degeneration and achieve the purpose of stepped treatment, thereby having clinical transformation value. In addition, the therapy combining the intervertebral disc fibrosis-inducing substance with the cell in the present disclosure allows the treatment regimen more personalized.
    Type: Application
    Filed: June 11, 2021
    Publication date: April 11, 2024
    Applicant: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
    Inventors: Jie ZHAO, Chen CHEN, Xiao YANG, Tangjun ZHOU, An QIN, Zhiqian CHEN, Kai ZHANG, Yifan ZHOU
  • Patent number: 11952913
    Abstract: A turbine blade includes a blade body, a division plate, a plurality of first protruding ridges, a plurality of second protruding ridges, a first jet hole group, and a second jet hole group. The blade body includes a suction-side wall surface and a pressure-side wall surface, which are provided with multiple film cooling holes. The stagnation region at the leading edge of the blade body is provided with multiple film cooling holes. The first and second jet hole groups are provided on the division plate. The first protruding ridges are provided on a suction-side inner wall surface, and the second ridges are provided on a pressure-side inner wall surface. An engine including the turbine blade is further provided.
    Type: Grant
    Filed: April 21, 2023
    Date of Patent: April 9, 2024
    Assignee: Shanghai Jiaotong University
    Inventors: Yu Rao, Yong Luan, Yamin Xu
  • Patent number: 11931892
    Abstract: A robotic system includes a support structure, a motor mount assembly, first and second parallel chains, a serial translation assembly, a sensor and a control module. The motor mount assembly includes rotary motors, where the rotary motors include a first rotary motor and a second rotary motor. The first and second parallel chains are connected to the movable platform, the rotary motors and the motor mount assembly. The serial translation assembly is connected to the supporting structure and the motor mount assembly and includes a linear actuator and a third rotary motor. The sensor is connected to the movable platform and detects force applied by a human operator on the movable platform and generates a signal indicative of the force applied. The control module controls the rotary motors and the third rotary motor based on the signal to assist the human operator in moving the movable platform.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: March 19, 2024
    Assignees: GM GLOBAL TECHNOLOGY OPERATIONS LLC, Shanghai JiaoTong University
    Inventors: Qiao Sun, Xianbao Chen, Jing Sun, Feng Gao, Dalong Gao, Ningjian Huang
  • Publication number: 20240069027
    Abstract: A use of nitrogen-doped carbon fluorescent quantum dots in preparation of aerobic glycolysis detection products is provided. The carbon-nitrogen fluorescent quantum dots are selected from one or more of C3N4 quantum dots, C2N quantum dots, and C3N quantum dots. The aerobic glycolysis detection products are reagents, based on a final volume of the reagents, the reagents comprise the carbon-nitrogen fluorescent quantum dots with a final concentration of 1 ?g/mL-1 mg/mL. The present disclosure realizes fluorescent labeling of NAD+ in living cells using the carbon-nitrogen fluorescent quantum dots, thus achieving fluorescent labeling and imaging of cells having aerobic glycolysis, which has the advantages of low cost, high efficiency, rapidity, and high accuracy.
    Type: Application
    Filed: December 28, 2021
    Publication date: February 29, 2024
    Applicants: SHANGHAI NINTH PEOPLE'S HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE, SHANGHAI INSTITUTE OF MICROSYSTEM AND INFORMATION TECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: JIPENG LI, SIWEI YANG, GUQIAO DING, HUIFANG ZHOU, XIANQUN FAN
  • Patent number: 11913042
    Abstract: Methods of preparing and using a highly active blood coagulation factor XI mutant and a gene therapy/editing vector thereof and a recombinant/fusion protein thereof. The nucleotide sequence of the mutant is as shown in SEQ ID NOs: 1-6, and the amino acid sequence is as shown in SEQ ID NO: 7.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: February 27, 2024
    Assignees: RUIJIN HOSPITAL SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Xuefeng Wang, Wenman Wu, Qiulan Ding
  • Publication number: 20240042109
    Abstract: A preparation method of drug-loaded micelles of an absorbable vascular stent coating for angiostenosis in an infant is provided, including the following steps: Si: dissolving a drug to be encapsulated in an appropriate amount of an emulsifying agent, adding a chitosan-poly(p-dioxohone) amphiphilic block copolymer (chitosan-b-PPDO copolymer), and thoroughly mixing to obtain a drug-copolymer solution; S2: adding the drug-copolymer solution obtained in S1 dropwise to an emulsifying agent aqueous solution prepared in advance, and continuously stirring to obtain a stable drug-loaded micellar solution; and S3: removing the emulsifying agent from the micellar solution obtained in S2 through vacuum evaporation, stirring a resulting concentrate, and centrifuging the concentrate to obtain a supernatant; and filtering the supernatant to obtain a filtrate, and subjecting the filtrate to dialysis to obtain the drug-loaded micelles.
    Type: Application
    Filed: March 29, 2022
    Publication date: February 8, 2024
    Applicant: XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Kun SUN, Jing SUN, Sun CHEN, Kai BAI, Yanan LU, Lu WANG, Fujun WANG, Fan ZHAO, Jihong HUANG
  • Patent number: 11886647
    Abstract: An in-air gesture control method based on visible light signals, which transmits light signals through a display device and collects its light signals reflected by hand, and after analysis, realizes gesture recognition; the transmitted light signals are in the visible light band; which can realize the gesture recognition and control on mobile devices without modifying hardware and a visible light-based gesture recognition system on commercial mobile devices; compared with the existing gesture recognition methods on commercial mobile devices, the invention avoids special hardware modification, that is, it does not require any additional components on the mobile device, such as a depth camera, and protects the user's privacy well.
    Type: Grant
    Filed: September 21, 2022
    Date of Patent: January 30, 2024
    Assignee: SHANGHAI JIAOTONG UNIVERSITY
    Inventors: Fan Wu, Zimo Liao, Guihai Chen
  • Patent number: 11881015
    Abstract: The present invention provides a high-precision identification method and system for substations, including building a Mask RCNN objection recognition network model based on convolutional neural networks; inputting acquired image information of a object into the Mask RCNN object recognition network model for preliminary recognition and outputting a recognition result of the object; using an information entropy to create a semantic decision tree and correcting the recognition result of the object according to a principle of relative correlation between different objects and outputting a final recognition decision result; reading the recognition decision result to obtain a true type of the object to be recognized. The present invention greatly improves the accuracy of image recognition of substations, and has a positive role in the research and development of automatic inspection equipment for inspection robots.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: January 23, 2024
    Assignee: Shanghai Jiaotong University
    Inventors: Yadong Liu, Yingjie Yan, Siheng Xiong, Ling Pei, Zhe Li, Peng Xu, Lei Su, Xiaofei Fu, Xiuchen Jiang
  • Publication number: 20230404763
    Abstract: A muscle function preservation type total temporomandibular joint prosthesis includes an articular fossa member (1) and an articular head member (2) abutting against the articular fossa member (1). The articular head member (2) includes a mandibular trailing edge fixing plate (21), a sigmoid notch fixing plate (22) and an articular head portion (23). The mandibular trailing edge fixing plate (21) is connected to a bottom end of the articular head portion (23) and extends downwards, and has a plate-shaped structure and includes a mandibular-trailing-edge-surface attaching surface. The sigmoid notch fixing plate (22) protrudes from one side of the mandibular trailing edge fixing plate (21) and extends in a direction away from the mandibular trailing edge fixing plate (21), and has a plate-shaped structure and includes a mandibular-ramus-proximal-sigmoid-notch-portion attaching surface.
    Type: Application
    Filed: November 18, 2020
    Publication date: December 21, 2023
    Applicant: SHANGHAI NINTH PEOPLE'S HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: CHI YANG, JISI ZHENG, ZIXIAN JIAO, MINJIE CHEN, WENBO JIANG
  • Publication number: 20230398071
    Abstract: The present invention relates to the field of hemodialysis and peritoneal dialysis, in particular to a fat emulsion dialysate, and preparation method and the use thereof. Provided in the present invention is a fat emulsion dialysate, comprising a long-chain fat emulsion oil, a medium-chain triglyceride, an anti-oxidant, sodium oleate, glycerin, phospholipid, and a solvent. Compared with traditional dialysis, the fat emulsion dialysate provided by the present invention has a better advantage for protein-bound toxin removal. In addition, the fat emulsion dialysate not only has a simple preparation method and a low cost, but also has good stability and safety, and remains stable at room temperature for 14 days without obvious precipitation. Thus, the fat emulsion dialysate can become a hemodialysis dialysate or peritoneal dialysate with broad application prospects, and has good industrialization prospects.
    Type: Application
    Filed: July 5, 2023
    Publication date: December 14, 2023
    Applicant: Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
    Inventors: Feng DING, Yifeng WANG, Yuqi SHEN, Jiaolun LI