Abstract: A terminal apparatus, a base station apparatus, a communication method, an integrated circuit, and a radio communication system are provided that enable a base station apparatus and a terminal apparatus to determine parameters relating to an uplink reference signal and efficiently communicate with each other.
Abstract: Avoided is falsely detecting a hand of a usual user being in contact with a contact sensor, instead of detecting an object, such as water, having a high dielectric constant being in contact with the contact sensor. A smartphone (1) includes a contact determination section (101) which determines that (i) a hand is in contact with a contact sensor (11) in a case where an output value outputted by the contact sensor (11) is not lower than TH1 and lower than TH3 and (ii) an object, such as water, having a high dielectric constant is in contact with the contact sensor (11) in a case where the output value is not lower than TH3.
Abstract: A driving device is used in an image reading apparatus, and reciprocates a scanning unit for reading an image on an original. The driving device comprises a pull member, a driving pulley which transmits driving force to the pull member, a following pulley which applies tension to the pull member and a pulley holder having a pulley axis which holds the following pulley rotatably. Then, the pulley axis has a lock pawl capable of locking an upper end portion of the following pulley and canceling engagement with the following pulley by being tilted toward a side of an axial center by elastic deformation. Furthermore, the lock pawl is arranged at a side of a tension acting direction from the pull member to the following pulley except the farthest position from the driving pulley among positions in a circumferential direction of the pulley axis. It is possible to attach and detach the following pulley easily at a time of maintenance or the like.
Abstract: This invention relates to indo line compounds of the structural formula I, or their pharmaceutically acceptable salts, wherein the variables are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
Abstract: Provided is a liquid crystal display device in which both a vertical electric field and a horizontal electric field are used and flickering is hardly recognized. The liquid crystal display device includes a liquid crystal panel and a control unit. The control unit includes a horizontal electric field control unit and a vertical electric field control unit. The horizontal electric field control unit controls the potentials of pairs of drive electrodes included in the liquid crystal panel, and thereby controls a horizontal electric field that is generated between each pair of drive electrodes. The vertical electric field control unit controls the potentials of a common electrode and an opposite electrode included in the liquid crystal panel, and thereby controls a vertical electric field that is generated between the common electrode and the opposite electrode.
Abstract: The present invention is directed to 4-fluoropiperidine compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Type:
Grant
Filed:
January 13, 2014
Date of Patent:
January 24, 2017
Assignee:
MERCK SHARP & DOHME CORP.
Inventors:
Andrew Cooke, Scott D. Kuduk, Craig Stump, Peter Williams
Abstract: An image display device is capable of displaying an image, in which occurrence of color unevenness is suppressed. A method of driving the image display device is also disclosed. In an area above the dotted line, red light is transmitted in a first sub-frame period. In second and third sub-frame periods, light blocking data are respectively supplied as green data and blue data. Therefore, green light and blue light cannot be transmitted through the area. Hence, a red image with no color unevenness is displayed in the area. In contrast, in an area under the dotted line, the red light is transmitted in the first sub-frame period, and the green light is transmitted in the second sub-frame period. As a result, in a viewed image of the area, there is color unevenness where green is mixed to red.
Abstract: A process is described for purifying insulin and insulin analogs that comprises high-pressure liquid chromatography with an acidic cation exchange medium performed in the presence of a water miscible organic modifier and at an elevated temperature followed by reverse phase chromatography performed in the presence of a water miscible organic modifier and at an elevated temperature.
Type:
Application
Filed:
March 11, 2015
Publication date:
January 19, 2017
Applicant:
Merck Sharp & Dohme Corp.
Inventors:
Allison D. Ortigosa, Michael P. Coleman, Shibu T. George, Michael A. Rauscher, Mark C. Sleevi, Kartoa Chow
Abstract: Radio transmission is performed even to a communication party whose bandwidth that can be used for transmission and reception is limited without having an influence of an offset of a DC component. A radio transmitter applied to an OFDMA communication system in which a plurality of different terminals performs communication using OFDM signals at the same time that includes a mapping part that allocates transmission power to each subcarrier, and also selects a subcarrier to which minimum power of the transmission power to be allocated is allocated and modulates transmission data in units of communication slots to output the modulated data; and a transmission part for transmitting radio signals including the modulated data using each of the subcarriers.
Abstract: Disclosed are pyrimidine carboxamide compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2), pharmaceutical compositions and uses thereof.
Type:
Application
Filed:
December 17, 2014
Publication date:
January 19, 2017
Applicants:
Merck Sharp & Dohme Corp., MSD R & D (China) Co. LTD.
Inventors:
Dong Ming Shen, Melissa Egbertson, Richard Berger, XiaoXia Qian, Yimin Qian, Bart Harper, Meng Yang, Zack Zhi Qiang Guo, Vanessa L. Rada, Deping Wang, Timothy A. Cernak, Christopher Sinz, Ming Wang, Jonathan E. Wilson, Shimin Xu
Abstract: A state information acquisition unit acquires state information indicating a state of a body, an information search unit searches for information on the state information from a content information storage unit that stores text information regarding broadcast content, and an output unit outputs information searched for by the information search unit.
Abstract: A terminal apparatus and a base station apparatus are provided that make it possible to efficiently report reception quality information in transmitting the reception quality information. The terminal apparatus includes a transmitting unit that transmits channel state information report feedback constituted by a given number of channel state information values corresponding to information pertaining to a network assisted interference cancellation function and a channel state information request. Channel state information values corresponding to a mode configuration in which channel state information is periodically reported are channel state information values that are suitable in a case of reception of a downlink signal without application of the network assisted interference cancellation function.
Abstract: In order to provide a substrate for light emitting devices having high heat radiating properties, dielectric strength voltage properties, light reflectivity, and excellent mass productivity, a substrate (5) includes an intermediate layer (11) containing ceramic which is formed on the surface of the aluminum base (10) by using an aerosol deposition method.
Abstract: A system for encoding and/or decoding a video bitstream that includes a base bitstream and enhancement bitstreams representative of a video sequence. The receiver receives a parameter set with constraints for parameters.
Abstract: An embodiment of the present invention provides an image display device capable of performing transmittance of a background and black display, while relaxing restriction of an installation position of a light source unit. The image display device includes a CF liquid crystal panel, a PDLC panel, and a first PDLC light source unit. The PDLC panel is positioned on the rear surface of the CF liquid crystal panel. At an image displaying time, the PDLC panel becomes in a spreading state. At this time, light source light of the first PDLC light source unit is spread by the PDLC panel and is emitted to the CF liquid crystal panel, and background light is spread by the PDLC panel. At an image non-displaying time, the PDLC panel becomes in a transmittance state. At this time, the background light is transmitted through the PDLC panel, and reaches the CF liquid crystal panel.
Abstract: A method is provided for synthesizing iron hexacyanoferrate (FeHCF). The method forms a first solution of a ferrocyanide source [A4Fe(CN)6.PH2O] material dissolved in a first solvent, where “A” is an alkali metal ion. A second solution is formed of a Fe(II) source dissolved in a second solvent. A reducing agent is added and, optionally, an alkali metal salt. The first and second solutions may be purged with an inert gas. The second solution is combined with the first solution to form a third solution in a low oxygen environment. The third solution is agitated in a low oxygen environment, and AX+1Fe2(CN)6.ZH2O is formed, where X is in the range of 0 to 1. The method isolates the AX+1Fe2(CN)6.ZH2O from the third solution, and dries the AX+1Fe2(CN)6.ZH2O under vacuum at a temperature greater than 60 degrees C.
Abstract: The present invention relates to methods of inducing an immune response to cytomegalovirus (CMV) using a genetically modified CMV that is conditionally replication defective. The methods of the invention can be used to treat and/or prevent primary CMV infection, infection due to reactivation of a latent CMV and a super-infection of a different strain of CMV that had been previously encountered. The present invention also relates to a replication defective CMV which has been recombinantly altered to allow for external control of viral replication. Compositions comprising the replication defective CMV are also encompassed by the present invention.
Type:
Grant
Filed:
September 4, 2012
Date of Patent:
January 17, 2017
Assignee:
Merck Sharp & Dohme Corp.
Inventors:
Tong-Ming Fu, Dai Wang, Muneeswara Babu Medi
Abstract: The present invention is directed to 2-pyridyloxy-3-substituted-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-substituted-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Abstract: Disclosed are the ERK inhibitors of formula (1.0) and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0). This invention provides compounds that are ERK inhibitors (i.e., ERK2 inhibitors). This invention also provides a pharmaceutical composition comprising an effective amount of at least one (e.g., 1) compound of formula (1.0) and a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
December 12, 2014
Date of Patent:
January 17, 2017
Assignee:
Merck Sharp & Dohme Corp.
Inventors:
Kathryn Lipford, Danielle Falcone, David L. Sloman, David J. Witter