Abstract: This invention relates to imidazopyridyl compounds of the structural formula: I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Abstract: An air conditioner includes: an air passage extending from a suction port to a blowout port, a heat exchanger at the upstream side of the air passage, a cross flow fan in the air passage on the downstream side of the heat exchanger, and an air passage wall provided in a downstream area of the cross flow fan to reach the blowout port. A restricting section that restricts an air passage sectional area is provided at a corner section of the side wall of the air passage wall. The restricting section has a shape by which the air passage sectional area has a rectangular cross section expanding from the upstream side to the downstream side and is restricted to reduce an enlargement ratio of the air passage sectional area. Further, the restricting section has a smooth restricting surface crossing the corner section of the cross section of the air passage.

Abstract: When no light enters a photodiode, a second current mirror circuit operates. Consequently, a current that decreases a potential difference between two terminals of a light-receiving element flows into a transistor of the second current mirror circuit and an output of an optical sensor becomes low. Meanwhile, when light enters the photodiode, a transistor of the light-receiving element is turned on and the second current mirror circuit stops operating. Consequently, the current that decreases the potential difference between the two terminals of the light-receiving element is stopped in the transistor of the second current mirror circuit and the output of the optical sensor becomes high. This makes it possible to provide an optical sensor that has a circuit in which an output of a light-receiving element does not depend on a photocurrent and that is capable of operating at a high speed.

Abstract: It is to provide a reflection sheet, light source device and display device, not only for uniforming the luminance of light emitted from a light source, but also for utilizing a single sheet material to form the reflection sheet having a frame portion that continues to all rims of a flat portion. The reflection sheet is provided with a flat portion that is formed in a substantially square shape, and a frame portion that is folded at a first fold formed on a rim of the flat portion. It is formed in a case shape. It is provided with three second folds divergent from a corner of the flat portion to a rim of a corner on the frame portion, between each corner of the flat portion and the rim of the corner on the frame portion. No gap and step are generated on the corner.

Abstract: Elements of the present invention relate to systems and methods for filtering a display source light illumination level with an adaptive filter based on the presence of a scene cut proximate to the current frame.

Abstract: An electronic device of the present invention includes a shift register SR provided integrally with a substrate, a first line 11 connected with a connection terminal 101 electrically connectable with an outside device provided independently of the shift registers SR, second lines 12a through 12c via which output waveforms of the shift register SR are extracted, and switching sections 13a through 13c by which the first line 11 and the second lines 12a through 12c are switched between an electrically connected condition and an electrically disconnected condition. With this, even in a case where the electronic device of the present invention is a liquid crystal display device having a driver monolithic structure, output waveforms of a drive circuit (electronic circuit) can be inspected.

Abstract: An image display apparatus operates in field sequence mode which effectively reduces the generation of color break. A color break strength calculating unit determines a color break strength that indicates the noticeability of the generation of the color break. A light-source signal generating unit controls each light source so that as the color break strength of a color mixed component having the highest color break strength is higher, the color mixed component is contained more in light output from a light-source unit during the extension subframe period. If there is present a first pixel region as an area including one or more pixel formation regions where an image containing the component of interest is displayed, the color break strength of the component of interest increases more as a magnitude of the component of interest is larger in the first pixel region.

Abstract: A light-emitting apparatus including: a substrate; an LED chip mounted on a first surface of the substrate; a fluorescent material-containing layer containing a first fluorescent material, which fluorescent material-containing layer is provided above the first surface of the substrate so as to cover the LED chip; and a color-adjusting fluorescent layer that contains a second fluorescent material, which color-adjusting fluorescent material layer is formed in a layer provided on an outer side of the fluorescent material-containing layer in an emission direction, the color-adjusting fluorescent layer being formed in dots. Thus, the present invention provides a light-emitting apparatus and a method for manufacturing the same, each making it possible to carry out fine color adjustment so as to prevent a subtle color shift that occurs due to a factor such as a difference in concentration of a fluorescent material or the like.

Abstract: Provided is an air conditioner for performing heating operation through supply of a current to a heating portion including a plurality of positive temperature coefficient (PTC) heaters to be connected to a power supply section, the air conditioner including: a heater output control section for controlling an output of the heating portion; and a plurality of pulse signal generating sections provided correspondingly to the plurality of PTC heaters, each for generating a predetermined pulse signal when a corresponding one of the plurality of PTC heaters is supplied with the current, in which the plurality of PTC heaters are subjected to detection as to whether each of the PTC heaters is in a connected state or in a non-connected state based on presence/absence of the predetermined pulse signal, and the heater output control section subjects the heating portion to output control which is adjusted according to the number of the PTC heaters in the connected state.

Abstract: An active matrix substrate includes a plurality of pixels arranged in a matrix, a plurality of capacitor lines (11b) extending in one of directions in which the pixels are aligned and in parallel to each other, a plurality of TFTs (5), one for each of the pixels, a protective film (16a) covering the TFTs (5), a plurality of pixel electrodes (18a) arranged in a matrix on the protective film (16a) and connected to the respective corresponding TFTs (5), and a plurality of auxiliary capacitors (6), one for each of the pixels. Each of the auxiliary capacitors (6) includes the corresponding capacitor line (11b), the corresponding pixel electrode (18a), and the protective film (16a) between the corresponding capacitor line (11b) and the corresponding pixel electrode (18a).

Abstract: A water level sensor (91) is provided in an auxiliary tank (39) whose bottom portion communicates to a bottom portion of a pot (41) for generating steam and which is opened to the atmosphere. When water in the pot (41) keeps boiling and the stop time of a pump (35) reaches a predetermined time (e.g., 60 sec.), the pump (35) is driven for a predetermined time (e.g., 6 sec.) to supply water to the pot (41). This temporarily suppresses the boiling of water in the pot (41), lowering a steam pressure in a space formed by an external circulation passage (60), a heating chamber, and the pot (41). The water level in the auxiliary tank (39) then returns to a normal one, making it possible to correctly detect the water level in the pot (41).

Abstract: This invention relates to tricyclic triazole compounds or their pharmaceutically acceptable salts. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the above-cited compounds or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.

Abstract: A display device equipped with a touch panel capable of correcting, with high precision, a line drawn upon the touch panel with an inclined touch pen or input member. A display device equipped with a touch panel includes a touch panel unit, a touch panel control unit, a pen incline information acquiring unit, a coordinate correction unit, and a display panel unit. The touch panel control unit detects a touch upon a touch panel surface, and acquires touch point coordinate information which is information for specifying a location which is touched on the touch panel surface. The pen incline information acquiring unit acquires pen or input member incline information, which is information relating to an angle which is formed by the touch pen and the touch panel surface when the touch pen and the touch panel face are in contact.

Abstract: A light-projecting device according to the present invention includes a plurality of light source units including (i) a light emitting section that emits light upon receiving a laser beam and (ii) a reflector. Each of the light source units project light to a corresponding one of light-projected spots which is a region to which light is projected in an illuminated region in a partitioning manner, and the illuminated region is formed by combining a plurality of the light-projected spot.

Abstract: Disclosed herein are compounds of Formula (I), wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing the compound of Formula (I) and use of the compound in the treatment of neurodegenerative diseases or conditions such as Alzheimer's disease.

Abstract: The present invention relates to a cytomegalovirus (CMV) which has been recombinantly altered to express a heterologous polypeptide and to allow for external control of viral replication. The heterologous polypeptide may be a polypeptide of interest such as an antigen, antibody or immune modulator. The CMV vectors of the invention are replication defective, or chemically controllable replication capable, or replication competent. The present invention also relates to uses of the CMV vectors such as inducing an immune response to an antigen or expressing an antibody or immune modulator in vivo. Compositions comprising the CMV expressing the heterologous polypeptide are also encompassed by the present invention.

Abstract: The present invention is directed to substituted cyclopropyl imidazopyridine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

Abstract: A light source device includes: a substrate having a front surface on which a light-emitting diode is mounted; and a case having a bottom plate that holds the substrate, wherein a driver circuit for driving the light-emitting diode is mounted on a rear surface of the substrate that is opposite to the front surface thereof, wherein an opening corresponding to a size of the light-emitting diode is formed in the bottom plate of the case, wherein the front surface of the substrate is fixed to a rear surface of the bottom plate of the case from outside of the case with the light-emitting diode fitted in the opening, and wherein a coating material with an emissivity of equal to or higher than 0.9 and equal to or lower than 1.0 is applied to an outer surface of four side walls of the case.

Abstract: Provided are methods of refolding and purifying lipoproteins on a chromatography column. In particular methods of refolding ApoL1 polypeptides using a hydrophobic interaction column (HIC). The present invention provides methods for the purification of an active form of a human lipoprotein, such as ApoL1. More particularly, the present invention relates to a method for renaturing an inclusion body of proteins expressed in a large quantity in E. coli into an active form using a hydrophobic interaction column and removal of impurities, e.g., endotoxins.

Abstract: A light projecting device of the present invention includes: a light source unit including (i) a laser element for emitting light, (ii) a light converging lens for converging the light emitted from the laser element, and (iii) a light emitting section for emitting light upon receipt of the light converged by the light converging lens; and a reflector for projecting light emitted from the light source unit. The light source unit is provided so as to be attached to or detached from a fixed part to which the light source unit is to be fixed.