Patents Assigned to Shimadzu Corporation
  • Publication number: 20220387298
    Abstract: The present invention chiefly aims to provide a novel composition for controlling indigenous bacterial flora in the skin which can enhance or improve the diversity of bacterial species in the indigenous bacterial flora in the skin relative to the condition before treatment. The present invention can include, for example, a composition (e.g., an ointment, a liquid) for controlling the diversity of bacterial species in indigenous bacterial flora in the skin, comprising an effective amount of earthworm lipids extracted from a raw earthworm (Lumbricus rubellus), and a base. The composition of the present invention is useful, for example, as a raw material for skin care products and cosmetics.
    Type: Application
    Filed: March 25, 2022
    Publication date: December 8, 2022
    Applicant: Shimadzu Corporation
    Inventors: Shigeaki SHIBAMOTO, Yasuko YONEDA, Ryogo TAKAI, Kohei YAMAMOTO
  • Patent number: 11519889
    Abstract: A display control unit (52) displays a screen for setting sample information on a display unit (8) for each sample placed in a sample placement section (20), and an input processing unit (53) receives information such as a culture name and seeding date and time information input by an operator via an operation unit (7), and stores the information in a storage unit (55). This file is transferred to a data processing unit (4) and stored in a sample information storage unit (40). After analyzing the respective samples in an LC-MS (3), a quantitative analysis unit (42) performs a quantitative analysis based on the obtained data, associates the analysis result with the sample information, and stores the data in an analysis result storage unit (43). As a result, the sample information and the analysis result of the respective samples in the preprocessing stage are associated with each other.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: December 6, 2022
    Assignee: Shimadzu Corporation
    Inventor: Kohei Yamamoto
  • Patent number: 11519936
    Abstract: A scanning probe microscope is provided with a cantilever having a probe at a tip end thereof, an optical system for emitting laser light onto the cantilever and detecting the laser light reflected by the cantilever, an imaging unit for imaging a range including a position of the tip end of the cantilever when adjusting an optical axis of the laser light, an image processing unit for detecting a position of the tip end of the probe and a position of a spot of the laser light from an image generated by the imaging unit, an optical axis adjustment unit for adjusting the optical axis of the laser light based on the detected positions, and a sample holder for holding a sample. The sample holder includes a mirror.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: December 6, 2022
    Assignee: Shimadzu Corporation
    Inventor: Masato Hirade
  • Patent number: 11521842
    Abstract: To improve the reliability of mutual diagnosis in a cancer determination by machine learning, m/z values of ions originating from tumor markers or similar substances used in other related tests are stored in a particular m/z-value database. A spectrum information filtering section deletes signal intensities at the m/z values stored in the particular m/z-value database from a large number of mass spectra classified by the presence or absence of cancer. Using the data which remain after the deletion as training data, a training processor obtains training-result information and stores it in a training result database. A judgment processor similarly deletes signal intensities at the predetermined m/z values from mass spectrum data obtained for a target sample to be judged. Then, based on the training-result information stored in the training-result database, the judgment processor determines whether the target sample should be classified into a cancerous group or non-cancerous group.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: December 6, 2022
    Assignee: SHIMADZU CORPORATION
    Inventors: Hideaki Izumi, Shigeki Kajihara
  • Patent number: 11519887
    Abstract: An analysis assistance method includes setting pressure in a first BPR to a value higher than a prescribed second set value with pressure in a second BPR set to a second set value, instructing a supercritical fluid chromatograph to supply a mobile phase to a supply flow path at a flow rate of the mobile phase that is to be theoretically supplied to a first flow path when the mobile phase is supplied to the supply flow path at a prescribed total flow rate and a prescribed sample introduction ratio, and gradually decreasing a set value of the pressure in the first BPR, and detecting a set value of the pressure in the first BPR at the time when supply of the mobile phase to a second flow path is stopped due to a decrease in set value of the pressure in the first BPR, as a first set value.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: December 6, 2022
    Assignee: SHIMADZU CORPORATION
    Inventor: Yuka Fujito
  • Patent number: 11519206
    Abstract: The present utility model relates to a graphite furnace locking device, comprising: a stationary part which is provided with a locking unit, a movable part which is arranged along a first direction facing the stationary part, the movable part being provided with a latch bolt unit; wherein, the movable part may move towards the stationary part along the first direction until the latch bolt unit and the locking unit are connected and then the locking device is in a locked state; the latch bolt unit provides a first elastic force for the movable part towards the direction of the stationary part; the locking unit is used to disconnect from the latch bolt unit, and then the locking device is in an unlocked state; the latch bolt unit provides a second elastic force for the movable part in a direction away from the stationary part, and the movable part can move away from the stationary part in the first direction under the action of the second elastic force to its initial position.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: December 6, 2022
    Assignee: Shimadzu Corporation
    Inventor: Shengsheng Sun
  • Patent number: 11519886
    Abstract: An autosampler is switched selectively between an injecting mode where a sampling flow path is incorporated into an analysis flow path of a liquid chromatograph and a loading mode where the sampling flow path is not incorporated into the analysis flow path and injects a sample into the analysis flow path at a position farther upstream than a separation column by being switched to the injecting mode with the sample held in the sampling flow path, and includes a clog determiner configured to acquire a sending liquid pressure of a liquid sending pump that sends a mobile phase in the analysis flow path, obtain a variation value of the liquid sending pressure when the injecting mode and the loading mode are switched and determine presence or absence of a clog in a system incorporated into the analysis flow path in the injecting mode based on the obtained variation value.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: December 6, 2022
    Assignee: Shimadzu Corporation
    Inventors: Yusuke Yokoi, Takaaki Fujita, Takashi Inoue, Kenichi Yasunaga
  • Publication number: 20220381736
    Abstract: A device for performing field asymmetric waveform ion mobility spectrometry, “FAIMS”, including a power supply that applies voltage waveforms to first and second segmented planar electrodes to produce an asymmetric time dependent electric field in an analytical gap for FAIMS analysis of ions . The voltage waveforms are configured such that the asymmetric time dependent electric field has curved contours of equal field strength when viewed in a plane perpendicular to the analytical axis so as to focus ions having different differential mobilities towards different spatial domains, each spatial domain extending along a respective curved contour of equal field strength when viewed in a plane perpendicular to the analytical axis. A focus controller is configured to allow a user to change the curvature of the contours of equal field strength so as to change the strength of focussing provided by the asymmetric time dependent electric field.
    Type: Application
    Filed: June 2, 2022
    Publication date: December 1, 2022
    Applicant: SHIMADZU CORPORATION
    Inventors: Roger GILES, Roch ANDRZEJEWSKI
  • Publication number: 20220381613
    Abstract: An infrared light source device includes: a heater portion which emits infrared light by being heated; and a cover member arranged to cover an entire circumference of the heater portion without contacting the heater portion, and having a hole formed therein for emitting the infrared light from the heater portion to outside. A material for the cover member is a pure aluminum (an aluminum alloy with a purity of 99% or more), which has a high heat reflectivity and is less likely to be denatured by heat dissipation from the heater portion.
    Type: Application
    Filed: April 26, 2022
    Publication date: December 1, 2022
    Applicant: SHIMADZU CORPORATION
    Inventor: Tadafumi KAMIKAKE
  • Publication number: 20220381604
    Abstract: [Object] To provide an electronic balance configured to uses a non-contact sensor to perform a predetermined operation, in which a greater number of operations than the number of non-contact sensors can be performed. [Means for solving problem] An electronic balance (1) includes: a non-contact sensor (31; 32) configured to detect an object; a state identifier (306) configured to identify a time pattern of a detection signal of the non-contact sensor (31; 32) as one of a plurality of previously defined time patterns; and an operation controller (30; 303; 304; 305) configured to control an operation of a predetermined section of the electronic balance (1) related to the time pattern identified by the state identifier.
    Type: Application
    Filed: May 16, 2022
    Publication date: December 1, 2022
    Applicant: SHIMADZU CORPORATION
    Inventors: Masahiro KATOH, Atsushi IIZUKA, Hiroshi HAMAMOTO
  • Patent number: 11513243
    Abstract: In the scatter estimation method of the present invention, Step S1 (first TOF projection data generation) and Step S4 (non-TOF scatter estimation algorithm) are performed, and Step S2 (second TOF projection data generation) and Step S3 (calculation of TOF direction distribution ratio) are performed, and Step S5 (calculation of TOF scatter projection data) is performed. A distribution ratio is obtained from the second TOF projection data measured in a scattered radiation energy window (low energy window). Since the target of distribution is non-TOF scatter projection data in a reconstruction data energy window (standard energy window), post-distribution TOF scatter projection data is obtained as approximate TOF scatter projection data in the reconstruction data energy window (standard energy window), and scatter estimation can be accurately performed.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: November 29, 2022
    Assignee: Shimadzu Corporation
    Inventor: Tetsuya Kobayashi
  • Publication number: 20220373540
    Abstract: A reagent kit comprising a first polypeptide including a part in any one of amino acid sequences (A) to (C), and a second polypeptide including a part in any one of amino acid sequences (A) to (C), which are consistent of different sequences from a sequence of the first polypeptide; (A) an amino acid sequence in SEQ ID NO: 1 with deletion of an amino acid sequence from position 1 to 69 and an amino acid sequence from position 204 to 221, (B) an amino acid sequence in SEQ ID NO: 1 with deletion of an amino acid sequence from position 1 to 69 and deletion or substitution of at least one of amino acid residues at positions 146 to 156, (C) the amino acid sequence (A) or (B) with further deletion of at least one of amino acid residues at positions 70 to 74.
    Type: Application
    Filed: May 19, 2022
    Publication date: November 24, 2022
    Applicant: SHIMADZU CORPORATION
    Inventor: Yuki OHMURO
  • Publication number: 20220373511
    Abstract: An analysis method of performing an analysis on a sample containing a first substance and a second substance that has an influence on an analysis of the first substance in regard to a concentration of the first substance, includes performing an analysis on the sample in regard to the concentration of the first substance to obtain sample analysis data, and deriving a result of analysis in regard to a concentration of the first substance based on the sample analysis data and adjustment information that is set based on the influence.
    Type: Application
    Filed: November 12, 2019
    Publication date: November 24, 2022
    Applicant: SHIMADZU CORPORATION
    Inventor: Yukihiko KUDO
  • Publication number: 20220373520
    Abstract: In a quantitative determination device 10 for brominated flame-retardant compounds, a storage section 41 holds a relative response factor 411 representing a relationship of a measured intensity of a compared compound to that of a reference compound selected from target compounds. A standard-sample measurer 43 acquires the intensity of the reference compound by measuring a standard sample, using an analyzer 10, 20. A target-sample measurer 45 acquires the intensities of the reference and compared compounds by measuring a target sample, using the analyzer. A reference-compound quantity determiner 46 determines a quantitative value of the reference compound in the target sample.
    Type: Application
    Filed: March 17, 2022
    Publication date: November 24, 2022
    Applicant: SHIMADZU CORPORATION
    Inventor: Yukihiko KUDO
  • Publication number: 20220376796
    Abstract: This optical communication device (1) is provided with: a plurality of light-receiving elements (11) configured to receive communication light, the plurality of light-receiving elements being provided so as to correspond to a plurality of channels; and a controller (15) configured to perform control to invalidate output from a light-receiving element that has received high-intensity light higher in light intensity than a predetermined value among the plurality of light-receiving elements.
    Type: Application
    Filed: November 8, 2019
    Publication date: November 24, 2022
    Applicants: SHIMADZU CORPORATION, JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY
    Inventors: Naoki NISHIMURA, Takao SAWA
  • Publication number: 20220375739
    Abstract: In order to improve the ionization efficiency and ion collection efficiency in an ESI ion source to achieve a higher level of analysis sensitivity while improving the throughput of the analysis, one mode of the present invention provides an ion analyzer equipped with an ion source employing an electrospray ionization method, where the ion source (2) includes: a plurality of capillaries (211-218) configured to spray a supplied liquid sample in the same direction; one or more auxiliary electrodes (23, 231-328) arranged so as to be surrounded by the plurality of capillaries; and a voltage supplier (24) configured to apply, to the plurality of capillaries, a DC high voltage for which the potential of the one or more auxiliary electrodes is used as a reference.
    Type: Application
    Filed: March 17, 2022
    Publication date: November 24, 2022
    Applicant: SHIMADZU CORPORATION
    Inventors: Masaru NISHIGUCHI, Akiko IMAZU, Osamu FURUHASHI
  • Patent number: 11506640
    Abstract: Obtaining sufficient suppression effect of channel diffusion and stably transferring solution are made possible even in a piping having an extremely small inner diameter used for an analysis apparatus such as an HPLC. A piping device for an analysis apparatus includes a piping equipped with a folded shape that suppresses inner channel diffusion, and a member directly or indirectly in contact with the piping from at least one side to support the piping to suppress deformation of the folded shape.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: November 22, 2022
    Assignee: SHIMADZU CORPORATION
    Inventors: Kengo Aoki, Masahide Gunji
  • Patent number: 11508565
    Abstract: An ion guide device includes a plurality of ring electrodes disposed in parallel, wherein each ring electrode includes at least 4 electrode units separated from each other, a channel for ion transmission is formed inside the plurality of ring electrodes, and an arrangement direction of the plurality of ring electrodes defines an axial direction of ion transmission; an radio-frequency voltage source, for applying out-of-phase radio-frequency voltages on the neighboring electrode units belonging to the same ring electrode, and applying in-phase radio frequency voltages on a neighboring electrode units along the axial direction, thereby forming an radio-frequency multipole field that confine ions in the ion guide device; and a direct-current voltage source, wherein the ions are transmitted off-axis and focused to a position closer to an inner surface of the ring electrode under a combined action of the radio-frequency voltage and the direct-current voltage.
    Type: Grant
    Filed: August 4, 2021
    Date of Patent: November 22, 2022
    Assignee: SHIMADZU CORPORATION
    Inventors: Keke Wang, Xiaoqiang Zhang, Wenjian Sun
  • Patent number: 11506645
    Abstract: The device is provided with a lamp lighting unit configured to perform an operation for lighting a deuterium lamp by controlling a lamp drive unit and a heater drive unit, an abnormality determination unit configured to determine, in a prescribed sequence, whether or not a voltage or a current detected by a lamp voltage detection unit, a lamp current detection unit, a heater voltage detection unit, and a heater current detection unit is abnormal, and an abnormality cause identification unit configured to identify, in a case the voltage or the current is determined to be abnormal by the abnormality determination, the cause of the abnormality, based on the timing at which the abnormality determination unit determines that the voltage or the current is abnormal.
    Type: Grant
    Filed: December 9, 2018
    Date of Patent: November 22, 2022
    Assignee: Shimadzu Corporation
    Inventors: Takuya Yonekura, Yugo Ishihara
  • Publication number: 20220365095
    Abstract: A mass spectrometry method includes detecting, in a first mass spectrometry of a sample containing a glycan having a plurality of sialic acids each modified differently, a plurality of oxonium ions derived from each of the plurality of sialic acids, and calculating relative values of intensities of the plurality of oxonium ions based on data obtained by the detection.
    Type: Application
    Filed: July 6, 2020
    Publication date: November 17, 2022
    Applicants: SHIMADZU CORPORATION, TOKYO METROPOLITAN GERIATERIC HOSPITAL AND INSTITUTE OF GERONTOLOGY
    Inventors: Takashi NISHIKAZE, Hiroki TSUMOTO