Patents Assigned to Shimadzu Corporation
  • Publication number: 20240068962
    Abstract: An X-ray imaging system is configured to acquire first and second images from a teacher X-ray image including an inspection target. Discrimination information to discriminate at least one of an area of the inspection target in the first and second images, and an area of a defect part is acquired. Machine learning for producing a learned model is performed by using input teacher data sets based on the first and second images, and output teacher data sets based on the discrimination information.
    Type: Application
    Filed: August 1, 2023
    Publication date: February 29, 2024
    Applicant: Shimadzu Corporation
    Inventors: Hiroaki TSUSHIMA, Ryuji SAWADA
  • Publication number: 20240069064
    Abstract: A method of assessing a probe by measuring a known sample whose shape is known with the probe in an electronic microscope, the known sample having a projection part on a surface thereof, and the projection part having a shape tapered toward a vertex thereof, the method comprising a step of measuring circle equivalent radius of the projection part, a step of comparing the circle equivalent radius with a first threshold value, and a step of determining that the probe is satisfactory when the width is less than the first threshold value, and a step of determining that the probe is unsatisfactory when the width is equal to or greater than the first threshold value.
    Type: Application
    Filed: June 9, 2021
    Publication date: February 29, 2024
    Applicant: SHIMADZU CORPORATION
    Inventors: Hiroshi ARAI, Hideo NAKAJIMA, Kenji YAMASAKI, Eiji IIDA, Akinori KOGURE
  • Patent number: 11915865
    Abstract: A movable-side magnet is provided to a movable portion in a vacuum chamber. A drive unit is provided outside the vacuum chamber, and drives the movable portion by exerting magnetic force on the movable-side magnet. The drive unit has a first magnet, a second magnet, and a moving mechanism (moving member). The first magnet exerts magnetic force of attracting the movable-side magnet. The second magnet is provided to be adjacent to the first magnet, and exerts magnetic force of repelling the movable-side magnet. The moving mechanism integrally moves the first magnet and the second magnet.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: February 27, 2024
    Assignee: SHIMADZU CORPORATION
    Inventors: Masaji Furuta, Kei Kodera, Kiyoshi Watanabe
  • Patent number: 11915919
    Abstract: A first spray unit (201) sprays a first sample into a first space (20) while charging the first sample. A second spray unit (202) sprays a second sample into the first space (20) or a second space (21) communicating with the first space (20) while charging the second sample. A determination unit (62) determines whether or not the second sample is sprayed from the second spray unit (202). A gas supply unit (74) supplies gas into the first space (20). A control unit (63) controls supply of the gas from the gas supply unit (74). In a case where the determination unit (62) determines that the second sample is sprayed from the second spray unit (202), the control unit (63) starts the supply of the gas from the gas supply unit (74) into the first space (20).
    Type: Grant
    Filed: May 27, 2019
    Date of Patent: February 27, 2024
    Assignee: SHIMADZU CORPORATION
    Inventor: Tomoya Kudo
  • Patent number: 11913917
    Abstract: An autosampler includes a retention path for injecting a sample into a mobile phase that flows through an analysis path to a column, the retention path including a needle at a downstream end and holding the sample, an injection path including a port at an upstream end for injecting into the analysis path, the sample injected from the needle into the port, a low-pressure path having an upstream end connected to a pump, and a valve that can switch between a first state in which an upstream analysis path and a downstream analysis path are connected and a downstream end of the low-pressure path and an upstream end of the retention path are connected and a second state in which the upstream analysis path and the upstream end of the retention path are connected and the downstream end of the injection path and the downstream analysis path are connected.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: February 27, 2024
    Assignee: SHIMADZU CORPORATION
    Inventors: Satoru Watanabe, Takashi Inoue
  • Publication number: 20240060987
    Abstract: Provided is a method of identifying a serovar of Salmonella bacteria including a step of subjecting a sample containing microorganisms to mass spectrometry to obtain a mass spectrum, a step of reading a mass-to-charge ratio m/z of a peak derived from a marker protein from the mass spectrum, and an identification step of identifying a serovar of Salmonella bacteria in the sample, based on the mass-to-charge ratio m/z, wherein the serovars of Salmonella bacteria are classified using cluster analysis using as an index the mass-to-charge ratio m/z derived from at least 12 types of ribosomal proteins S8, L15, L17, L21, L25, S7, SODa, peptidylprolyl isomerase, gns, YibT, YaiA and YciF as the marker proteins.
    Type: Application
    Filed: July 13, 2023
    Publication date: February 22, 2024
    Applicants: SHIMADZU CORPORATION, MEIJO UNIVERSITY
    Inventors: Hiroto TAMURA, Naomi YAMAMOTO, Teruyo KATO, Keisuke SHIMA, Shinji FUNATSU
  • Patent number: 11905946
    Abstract: A backup ring is for contacting with and supporting a plunger seal which is for sealing a pump chamber provided in a pump head of a plunger type liquid feeding pump. The backup ring includes a maximum outer diameter portion of a cylindrical shape and a smaller outer diameter portion. The maximum outer diameter portion includes a maximum outer diameter in a plunger seal supporting surface side that makes contact with a rear surface of the plunger seal. The smaller outer diameter portion includes a smaller outer diameter than the maximum outer diameter portion in at least one part of a portion other than the maximum outer diameter portion.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: February 20, 2024
    Assignee: Shimadzu Corporation
    Inventors: Toshiki Sano, Shinya Imamura, Masataka Nikko
  • Patent number: 11906477
    Abstract: A tensile testing machine includes: a testing machine body that executes a tensile test; an instruction reception unit that receives an operation instruction for the testing machine body on the basis of an operation from a user; and an instruction storage unit that stores contents and an order of instruction information indicating the operation instruction, which is received by the instruction reception unit, for the testing machine body.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: February 20, 2024
    Assignee: SHIMADZU CORPORATION
    Inventor: Tohru Matsuura
  • Patent number: 11905527
    Abstract: A gel composition contains an amphiphilic block polymer having a hydrophilic block chain and a hydrophobic block chain. An organogel is obtained by mixing the amphiphilic block polymer with an organic solvent, and a xerogel is formed by removing the organic solvent from the organogel. A hydrogel is formed by mixing the xerogel with water or an aqueous solution. A hydrogel encapsulating cells to be cultured may be formed by mixing a xerogel with an aqueous solution containing the cells such as a cell culture solution.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: February 20, 2024
    Assignee: SHIMADZU CORPORATION
    Inventor: Hayato Matsui
  • Patent number: 11906522
    Abstract: Glycans having a branched structure are labeled with a labeling agent, such as 2-aminobenzoic acid, having one site that is easily negatively charged. At this time, reduction which is usually performed in labeling by reduction amination is not performed. A sample for mass spectrometry containing the labeled form of glycans thus obtained is prepared, and is subjected to MS/MS analysis in negative ion mode. In the MS/MS spectra obtained by the MS/MS analysis, peaks of E ions, D ions and the like which reflect the branched structure clearly appear. As a result, structural analysis of an entirety of the glycan including the branched structure can be easily performed.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: February 20, 2024
    Assignee: SHIMADZU CORPORATION
    Inventor: Takashi Nishikaze
  • Patent number: 11908671
    Abstract: An ion analyzer includes a reaction chamber into which precursor ions derived from a sample component are introduced, a radical irradiation unit that generates and emits a predetermined type of radicals, a standard substance supply unit that individually supplies kinds of standard substances to the reaction chamber, where activation energy of radical addition reaction is known for each of the kinds of standard substances, and the activation energies are different in magnitude, an ion measurement unit that measures an amount of predetermined product ions generated from precursor ions derived from the standard substance by irradiation with the radicals, and a radical temperature calculation unit that obtains an amount of radicals that caused the radical addition reaction from the amount of the predetermined product ions and obtains a radical temperature based on a relationship between the amount of the radicals obtained for each kind of standard substance and activation energy.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: February 20, 2024
    Assignees: SHIMADZU CORPORATION, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Hidenori Takahashi, Daiki Asakawa
  • Patent number: 11906475
    Abstract: In a case where control input is performed via a low-pass filter, a control gain more appropriate for both stability and responsiveness is set according to setting of the low-pass filter. A control unit (21) performs control input for a load mechanism (40) via a low-pass filter, discriminates a stability of a control system including the load mechanism (40) and the low-pass filter when setting of the low-pass filter is changed, sets an appropriate control gain based on a maximum control gain at which an excess amount of a measured value with respect to a target value is equal to or less than a predetermined value within a range where that the control system is stable, and controls an operation of the load mechanism (40) by using the appropriate control gain.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: February 20, 2024
    Assignee: SHIMADZU CORPORATION
    Inventor: Tohru Matsuura
  • Patent number: 11906449
    Abstract: A mass spectrometer (1) includes: an ionization section (201) configured to generate ions from a sample; a mass separation section (231, 235) configured to separate ions generated by the ionization section according to mass-to-charge ratio; an ion detector (237) configured to detect an ion separated by the mass separation section; an ion capture section (31) configured to capture ions separated by the mass separation section; and an electron beam detection section (32) configured to detect an electron beam diffracted by ions captured within the ion capture section (31). This mass spectrometer is capable of performing, in a single measurement operation, both a mass spectrometric analysis and an electron-beam diffraction measurement for distinguishing between isomers. The electron-beam diffraction measurement can be more efficiently performed than in a conventional device of this type.
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: February 20, 2024
    Assignee: SHIMADZU CORPORATION
    Inventors: Osamu Furuhashi, Junichi Taniguchi
  • Publication number: 20240053357
    Abstract: An analysis method includes a humidity measurement step of measuring humidity; a binding step of bringing a sample containing an analyte into contact with a carrier to bind the analyte to the carrier; an elution step of bringing the carrier to which the analyte is bound into contact with an eluate containing a volatile organic solvent to elute the analyte into the eluate; a disposition step of disposing the eluate into which the analyte has been eluted on a measurement plate for mass spectrometry; and a detection step of detecting the analyte by mass spectrometry, in which in the elution step, a use amount of the eluate is determined according to the humidity.
    Type: Application
    Filed: December 1, 2021
    Publication date: February 15, 2024
    Applicant: SHIMADZU CORPORATION
    Inventor: Naoki KANEKO
  • Publication number: 20240053306
    Abstract: Provided is a quantitative determination method for sulfur compounds in a target group selected from a plurality of groups, e.g., a group including cysteine and related reactive sulfurs, including the steps of: performing an LC/MS/MS measurement of a standard substance having a known concentration of a base compound, e.g.
    Type: Application
    Filed: August 4, 2023
    Publication date: February 15, 2024
    Applicants: SHIMADZU CORPORATION, Shimadzu Techno-Research, Inc.
    Inventors: Akihiro KUNISAWA, Atsuhiko TOYAMA, Takaaki AKAIKE, Tsubasa IBUSHI
  • Patent number: 11898949
    Abstract: By irradiating target liquid L containing fine bubbles with ultrasonic waves from an ultrasonic irradiation device 102, the fine bubbles in the target liquid L is reduced. By irradiating the target liquid L with ultrasonic waves, fine bubbles in the target liquid L can be reduced effectively. By using ultrasonic waves, bubbles with small diameters, particularly fine bubbles, can be effectively reduced, so that fine bubbles in the target liquid L can be efficiently reduced.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: February 13, 2024
    Assignees: Shimadzu Corporation, National Institute of Technology and Evaluation, Fine Bubble Industries Association
    Inventors: Seika Ohuchi, Mitsuru Tanaka, Haruo Shimaoka
  • Patent number: 11899030
    Abstract: A plate changer includes a casing that stores a sample plate and one or a plurality of first rack plates that each support the sample plate. One or a plurality of plate supporters that respectively support the one or plurality of first rack plates at different heights are provided in the casing. Each first rack plate is configured to be supportable on and removable from any of the one or plurality of plate supporters. The plate changer further includes a detector that detects whether the first rack plate is supported on each plate supporter.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: February 13, 2024
    Assignee: SHIMADZU CORPORATION
    Inventors: Kodai Imaeda, Takuya Sawada
  • Publication number: 20240044800
    Abstract: Provided is a microscopic Raman device including: a first laser light source that generates a first laser light; a second laser light source that generates a second laser light having a wavelength different from a wavelength of the first laser light; a first optical element; a second optical element; a third optical element; a fourth optical element; and a spectrometer. When the first laser light is reflected by the first optical element and passes through the third optical element to irradiate a sample, a first Raman scattered light is generated from the sample. When the second laser light is sequentially reflected by the second optical element, the fourth optical element, and the third optical element to irradiate the sample, a second Raman scattered light is generated from the sample. The first Raman scattered light passes through the third optical element and the first optical element to enter the spectrometer.
    Type: Application
    Filed: July 27, 2023
    Publication date: February 8, 2024
    Applicant: SHIMADZU CORPORATION
    Inventor: Tomoyo TAO
  • Publication number: 20240044810
    Abstract: In an X-ray imaging, first and second images of X-ray images corresponding to different emission angles are generated. In the X-ray imaging system, based on positions of a target part included in an inspection target in the first and second images, and an angle difference between the emission angles of X-rays that are emitted to generate the first and second images, a three-dimensional position of the target part is calculated by using triangulation.
    Type: Application
    Filed: August 3, 2023
    Publication date: February 8, 2024
    Applicant: Shimadzu Corporation
    Inventors: Ryuji SAWADA, Hitomi YOSHIYAMA, Hiroaki TSUSHIMA
  • Patent number: D1014759
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: February 13, 2024
    Assignee: SHIMADZU CORPORATION
    Inventor: Ryo Takegawa