Patents Assigned to Shimadzu Corporation
  • Patent number: 9839932
    Abstract: A surface chemical treatment apparatus provided with: a first conduit having an opening at one end and communicating with a liquid supply means at the other end; a second conduit having at one end an opening that surrounds the opening of the first conduit and communicating with a liquid suction means at the other end; and a moving mechanism for moving the openings of the first and second conduits relative to the solid phase surface, so as to make a surface chemical treatment possible in a fine pattern by allowing the patterning solution to be dispensed through the opening of the first conduit while allowing the solution to be suctioned up together with the surrounding liquid phase or gas phase medium through the opening of the second conduit that surrounds the opening of the first conduit and, thus, preventing seepage of the solution in all directions.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: December 12, 2017
    Assignees: SHIMADZU CORPORATION, TOKYO METROPOLITAN UNIVERSITY, WASEDA UNIVERSITY
    Inventors: Katsumi Uchiyama, Hizuru Nakajima, Ming Yang, Hulie Zeng, Yoshiyuki Sugahara, Takahiro Nishimoto
  • Patent number: 9839401
    Abstract: Disclosed herein is a partially movable radiation tomography apparatus capable of superimposing an anatomical image and a functional image without causing misalignment. The apparatus of the disclosure includes a device associated with a CT gantry having a top board, and a device associated with a PET gantry. The latter device is attachable and removable to/from the former device. This apparatus can reduce positional misalignment between the images captured by these devices. The present disclosure involves making a correction for positioning the subject images captured by the devices associated with the respective gantries with respect to each other based on a calibration image on which markers m attached to those gantries are shot. Such a configuration allows for positioning the subject images with possible misalignment between the gantries taken into account, and eventually reducing positional misalignment between the subject images captured by the devices associated with the respective gantries.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: December 12, 2017
    Assignee: Shimadzu Corporation
    Inventor: Ayako Akazawa
  • Patent number: 9841407
    Abstract: A liquid chromatograph analysis method and a liquid chromatograph minimize analysis time when performing analyses by switching columns and mobile phases. Liquid chromatograph 100 for performing a plurality of analyses according to a schedule table includes: mobile phase switching sections 15, 16 for switching a plurality of mobile phases to select a mobile phase to be used in analysis; column switching sections 31, 33 for switching a plurality of columns 32a-32f to select a column to be used in analysis; and control section 60 including memory 61 for storing an equilibration time of each of the plurality of columns 32a to 32f and an equilibration controller 66 for controlling column equilibration. If used columns or used mobile phases are different between two consecutively executed analyses, equilibration controller 66 equilibrates a column used in the later of the two analyses over an equilibration time read out from memory 61.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: December 12, 2017
    Assignee: SHIMADZU CORPORATION
    Inventor: Hiroshi Ohashi
  • Publication number: 20170350920
    Abstract: The invention provides a scanning probe microscope capable of eliminating the influence of vibration noise and obtaining, accurately and with high resolution, surface information of a sample S. A scanning probe microscope 1 includes: a main body unit 10; a control unit 30; and a wireless stand 60 that is connected to the control unit 30 through a power supply signal cable 42 and includes a power supplying coil 63 and a transmission and reception unit 64. The main body unit 10 includes: a cantilever 21 with a probe 21a; a sensor 23 for detecting displacement of the cantilever 21; an XYZ drive mechanism 25 that is controlled by the control unit 30 to move the cantilever 21 or the sample S; a vibration isolation mechanism 12; a power receiving coil 13; and a transmission and reception unit 14 for communicating with the transmission and reception unit 64.
    Type: Application
    Filed: October 24, 2014
    Publication date: December 7, 2017
    Applicant: SHIMADZU CORPORATION
    Inventor: Yuichiro IKEDA
  • Publication number: 20170350690
    Abstract: A defect detection apparatus is provided that can inspect a measurement region of a target object at one time and without inconsistencies arising within the measurement region. A defect detection apparatus 10 includes: a generation unit (signal generator 11 and vibrator 12) for generating an elastic wave in a target object S; an illumination unit (pulsed laser light source 13 and illumination light lens 14) for performing stroboscopic illumination onto a measurement region of a surface of the target object S; and a displacement measurement unit (speckle shearing interferometer 15) for collectively measuring displacements in a normal direction at each point of the measurement region with respect to at least three mutually-different phases of the elastic wave by controlling a phase of the elastic wave and a timing of the stroboscopic illumination.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 7, 2017
    Applicant: SHIMADZU CORPORATION
    Inventors: Takahide HATAHORI, Kenji TAKUBO
  • Publication number: 20170352525
    Abstract: When conducting imaging mass analysis for a region to be measured on a sample, an individual reference value calculating part obtains a maximum value in Pi/Ii of respective measuring points, and stores the value together with measured data as an individual reference value. When performing comparison analysis for a plurality of the data obtained from different samples, a common reference value determining part reads out corresponding a plurality of the individual reference values and determines a minimum value as a common reference value Fmin. A normalization calculation processing part normalizes the respective intensity values by multiplying the intensity values read out from an external memory device by a normalization coefficient long_MaxĂ—(Fmin/Pi) obtained from the common reference value Fmin, TIC values Pi at the respective measuring points, and a maximum allowable value long_Max of a variable storing the intensity values at the time of operation.
    Type: Application
    Filed: December 22, 2014
    Publication date: December 7, 2017
    Applicant: Shimadzu Corporation
    Inventors: Masahiro IKEGAMI, Shigeki KAJIHARA
  • Patent number: 9835571
    Abstract: The detection surface of each of a plurality of detection elements is arranged on an arc along a diffractometer circle (reference circle). This allows each detection element to detect X-rays diffracted by a specimen at the focal position. Because this prevents errors in the X-ray intensity detected by each detection element, more accurate diffraction information can be obtained. As a result, a more accurate analysis can be performed in less time by detecting X-rays diffracted by the specimen using a plurality of detection elements.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: December 5, 2017
    Assignee: SHIMADZU CORPORATION
    Inventors: Tetsuya Yoneda, Takao Marui, Masashi Matsuo
  • Patent number: 9835598
    Abstract: A heat insulating member 13 is provided on the outer circumference of a connection pipe 11. The heat insulating member 13 includes: a tube 12; and an air layer 15 between the connection pipe 11 and the tube 12. Accordingly, it is possible to always keep the temperature of a sample component at the time of detection by a detector constant and thus prevent an influence of the temperature on an output result of the detector, in a low flow rate analysis using a modularized column unit and a modularized detection unit.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: December 5, 2017
    Assignee: SHIMADZU CORPORATION
    Inventors: Masato Watanabe, Masahide Gunji
  • Patent number: 9833208
    Abstract: There are provided a gantry with an opening having a central axis inclined so that the opening is directed obliquely downward, a chair disposed obliquely below the gantry, and having an inclined surface for supporting a patient M so that the central axis of the opening and a body axis A of the patient M become parallel, and a chair moving mechanism for driving at least one of the gantry and the chair to insert the patient M into the opening parallel to the central axis of the opening of the gantry. Thus, images can be picked up of the patient M in a comfortable position safely and efficiently.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: December 5, 2017
    Assignee: Shimadzu Corporation
    Inventor: Masaharu Amano
  • Patent number: 9835483
    Abstract: A hydraulic pressure source includes an oil tank for storing hydraulic oil, a hydraulic pump, a motor for driving this hydraulic pump, and an inverter for changing a rotational frequency of the motor. A pipe line for drawing the hydraulic oil from the oil tank by operation of the hydraulic pump branches to a supply pipe line for supplying the hydraulic oil to the hydraulic cylinder, and a release pipe line for releasing superfluous hydraulic oil into the oil tank. The release pipe line has arranged thereon a pressure regulating mechanism and a flowmeter which measures a flow rate of the hydraulic oil flowing into the release pipe line. Based on a measurement value of the flowmeter, the inverter is operable to change the rotational frequency of the motor to become a necessary minimum rotational frequency.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: December 5, 2017
    Assignee: SHIMADZU CORPORATION
    Inventor: Motofumi Kimura
  • Publication number: 20170343519
    Abstract: A liquid chromatograph includes: a concentration column for capturing a target component; an analysis column for separating the target component from other components; first passage-switching units for switching between the state of forming a passage through which a sample-introduction mobile phase containing the liquid sample is fed to the concentration column, and the state of forming a passage through which an eluant for eluting the target component captured in the concentration column is fed to the concentration column; a storage unit for storing the eluant; and a second passage-switching unit for switching between the state of forming a passage through which an analysis mobile phase is fed to the analysis column and a passage through which the eluant from the concentration column is fed to the storage unit, and the state of forming a passage through which analysis mobile phase is fed to the analysis column via the storage unit.
    Type: Application
    Filed: December 15, 2014
    Publication date: November 30, 2017
    Applicant: SHIMADZU CORPORATION
    Inventors: Tairo OGURA, Mikael LEVI
  • Publication number: 20170343823
    Abstract: This dynamic image processing device (20) for a head mounted display includes an attitude detection means (30) capable of detecting the attitude of an imaging device affixed to the head of a user, a first image deviation amount calculation means (41) that calculates a first image deviation amount (G1) in the yawing and pitching directions of the imaging device based on the detection result of the attitude detection means, a second image deviation amount calculation means (42) that calculates a second image deviation amount (G2) between a past image (52) and a current frame image (51) based on the first image deviation amount, the current frame image captured by the imaging device, and the past image, and an image synthesis means (43) that corrects the past image based on the second image deviation amount and synthesizes the past image and the current frame image.
    Type: Application
    Filed: December 2, 2015
    Publication date: November 30, 2017
    Applicant: SHIMADZU CORPORATION
    Inventors: Yusuke TAGAWA, Kaname HASEBE, Kazuho TAWADA
  • Patent number: 9829498
    Abstract: A piercer washing port is provided at a position on the trajectory of a piercer differing from the sampling position. The piercer washing port is cylindrically shaped and has an opening for inserting the piercer in the upper surface and a washing space for housing the piercer inserted from the opening. Air injection ports for injecting air and washing liquid expelling ports for expelling water serving as a washing liquid are provided on the inside wall surface of the piercer washing port. The air injection ports are provided at four locations equally spaced on the periphery along the inside wall surface of the washing space. The washing liquid expelling ports 44 are provided at four locations equally spaced on the periphery along the inside wall surface of the washing space at different positions than those of the air injection ports.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: November 28, 2017
    Assignee: SHIMADZU CORPORATION
    Inventors: Takanori Onoki, Akiko Bamba, Hiroyuki Otsuki, Shoji Ide
  • Publication number: 20170336254
    Abstract: A photodetector includes a plurality of photoelectric conversion elements arranged within a photosensitive-element area constituting one photosensitive element; the plurality of detection circuits each of which is provided for one of the plurality of photoelectric conversion elements, each of the detection circuits including a capacitor; and a signal processing section for totaling output signals produced by the plurality of detection circuits.
    Type: Application
    Filed: July 8, 2015
    Publication date: November 23, 2017
    Applicant: SHIMADZU CORPORATION
    Inventors: Ryuta HIROSE, Tomohiro KARASAWA, Hideki TOMINAGA
  • Publication number: 20170336370
    Abstract: The EM algorithm for a Gaussian mixture model is applied to the separation of peaks that overlap one another on a chromatogram. However, the number of overlapping components is unknown. Thus, a suitable number of models is set, and the fitting of model parameters is performed while an actually measured signal is appropriately divided for each model by the EM algorithm. Then, when a solution converges, a determination is made as to whether a peak-like waveform is present in a residue signal that is not divided. When the peak-like waveform is present, a peak model is added. The EM algorithm is executed again. In the M step, optimization is performed using, not only a simple Gaussian function, but also a modified Gaussian function assuming a tailing. In the M step, the estimation of a spectrum assuming a chromatogram and the estimation of a chromatogram assuming a spectrum are repeatedly performed.
    Type: Application
    Filed: September 3, 2014
    Publication date: November 23, 2017
    Applicant: SHIMADZU CORPORATION
    Inventor: Akira NODA
  • Patent number: 9826613
    Abstract: An X-ray tube assembly for generating an X-ray, comprises: a filament including a plurality of electric flow paths; and an adjustor configured to adjust at least one of values of current flowing through the plurality of electric flow paths to adjust an electron emission area of the filament.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: November 21, 2017
    Assignee: Shimadzu Corporation
    Inventor: Sadamu Tomita
  • Patent number: 9820710
    Abstract: Provided is a preview image generating section configured to generate preview image during radiography for the purpose of providing a radiation tomography apparatus that allows suppression of unnecessary imaging time by displaying a condition of an image during the radiography in the process of diagnosis. An operator can recognize from the preview image how a subject appears in the image in a radiation tomography apparatus also during the radiography. This allows stopping the radiography before a diagnostic image having a suitable level of clearness for diagnosis is generated. As a result, a shorter imaging time is achieved, and burden to the subject can be suppressed.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: November 21, 2017
    Assignee: Shimadzu Corporation
    Inventor: Junichi Ohi
  • Patent number: 9822783
    Abstract: A vacuum pump comprises a cylindrical rotor; a cylindrical stator which discharges gas in cooperation with the rotor; a base housing at least a part of the stator and having a through hole formed at a position facing an outer periphery of the stator; a heating member passing through the through hole from an atmosphere side to a vacuum side to have thermal contact with an outer peripheral surface of the stator to heat the stator; and an axial seal member which vacuum-seals a gap between the through hole and the heating member.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: November 21, 2017
    Assignee: SHIMADZU CORPORATION
    Inventor: Tetsuya Tsubokawa
  • Patent number: 9821250
    Abstract: In a preparative separation-purification system for passing a solution containing a target component through a trap column to capture the target component in the column, and for subsequently passing an eluting solvent through the column to elute the captured component and collect it in a container, a dilution passage is merged with a collection passage for sending an eluate from the outlet end of the trap column to the collection container, and a diluting liquid is intermittently introduced through the dilution passage into the collection passage. The diluting liquid lowers the concentration of the target component in the eluate and impedes the deposition of the target component. Thus, clogging of the passage due to the deposition of the target component eluted from the trap column is effectively prevented.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: November 21, 2017
    Assignee: Shimadzu Corporation
    Inventors: Tomoyuki Yamazaki, Przemyslaw Stasica, Bob Boughtflower
  • Patent number: 9821078
    Abstract: Provided is a polymeric micelle pharmaceutical preparation that can increase the ratio of contrast at tumor site to background contrast in a short period of time after administration of a lactosome and can suppress the ABC phenomenon so that the lactosome can be administered more than once within a short span. A branched-type amphiphilic block polymer comprising: a multi-branched hydrophilic block comprising sarcosine; and a hydrophobic block comprising polylactic acid. The branched-type amphiphilic block polymer, wherein the number of branches of the hydrophilic block is 3. A molecular assembly comprising the branched-type amphiphilic block polymer. The molecular assembly further comprising a linear type amphiphilic block polymer.
    Type: Grant
    Filed: February 27, 2016
    Date of Patent: November 21, 2017
    Assignees: SHIMADZU CORPORATION, KYOTO UNIVERSITY
    Inventors: Eiichi Ozeki, Shunsaku Kimura, Akira Makino