Patents Assigned to Shimadzu Corporation
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Publication number: 20240060987Abstract: Provided is a method of identifying a serovar of Salmonella bacteria including a step of subjecting a sample containing microorganisms to mass spectrometry to obtain a mass spectrum, a step of reading a mass-to-charge ratio m/z of a peak derived from a marker protein from the mass spectrum, and an identification step of identifying a serovar of Salmonella bacteria in the sample, based on the mass-to-charge ratio m/z, wherein the serovars of Salmonella bacteria are classified using cluster analysis using as an index the mass-to-charge ratio m/z derived from at least 12 types of ribosomal proteins S8, L15, L17, L21, L25, S7, SODa, peptidylprolyl isomerase, gns, YibT, YaiA and YciF as the marker proteins.Type: ApplicationFiled: July 13, 2023Publication date: February 22, 2024Applicants: SHIMADZU CORPORATION, MEIJO UNIVERSITYInventors: Hiroto TAMURA, Naomi YAMAMOTO, Teruyo KATO, Keisuke SHIMA, Shinji FUNATSU
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Patent number: 11905946Abstract: A backup ring is for contacting with and supporting a plunger seal which is for sealing a pump chamber provided in a pump head of a plunger type liquid feeding pump. The backup ring includes a maximum outer diameter portion of a cylindrical shape and a smaller outer diameter portion. The maximum outer diameter portion includes a maximum outer diameter in a plunger seal supporting surface side that makes contact with a rear surface of the plunger seal. The smaller outer diameter portion includes a smaller outer diameter than the maximum outer diameter portion in at least one part of a portion other than the maximum outer diameter portion.Type: GrantFiled: November 8, 2018Date of Patent: February 20, 2024Assignee: Shimadzu CorporationInventors: Toshiki Sano, Shinya Imamura, Masataka Nikko
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Patent number: 11906522Abstract: Glycans having a branched structure are labeled with a labeling agent, such as 2-aminobenzoic acid, having one site that is easily negatively charged. At this time, reduction which is usually performed in labeling by reduction amination is not performed. A sample for mass spectrometry containing the labeled form of glycans thus obtained is prepared, and is subjected to MS/MS analysis in negative ion mode. In the MS/MS spectra obtained by the MS/MS analysis, peaks of E ions, D ions and the like which reflect the branched structure clearly appear. As a result, structural analysis of an entirety of the glycan including the branched structure can be easily performed.Type: GrantFiled: November 7, 2016Date of Patent: February 20, 2024Assignee: SHIMADZU CORPORATIONInventor: Takashi Nishikaze
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Patent number: 11906477Abstract: A tensile testing machine includes: a testing machine body that executes a tensile test; an instruction reception unit that receives an operation instruction for the testing machine body on the basis of an operation from a user; and an instruction storage unit that stores contents and an order of instruction information indicating the operation instruction, which is received by the instruction reception unit, for the testing machine body.Type: GrantFiled: October 26, 2021Date of Patent: February 20, 2024Assignee: SHIMADZU CORPORATIONInventor: Tohru Matsuura
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Patent number: 11908671Abstract: An ion analyzer includes a reaction chamber into which precursor ions derived from a sample component are introduced, a radical irradiation unit that generates and emits a predetermined type of radicals, a standard substance supply unit that individually supplies kinds of standard substances to the reaction chamber, where activation energy of radical addition reaction is known for each of the kinds of standard substances, and the activation energies are different in magnitude, an ion measurement unit that measures an amount of predetermined product ions generated from precursor ions derived from the standard substance by irradiation with the radicals, and a radical temperature calculation unit that obtains an amount of radicals that caused the radical addition reaction from the amount of the predetermined product ions and obtains a radical temperature based on a relationship between the amount of the radicals obtained for each kind of standard substance and activation energy.Type: GrantFiled: April 2, 2019Date of Patent: February 20, 2024Assignees: SHIMADZU CORPORATION, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Hidenori Takahashi, Daiki Asakawa
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Patent number: 11905527Abstract: A gel composition contains an amphiphilic block polymer having a hydrophilic block chain and a hydrophobic block chain. An organogel is obtained by mixing the amphiphilic block polymer with an organic solvent, and a xerogel is formed by removing the organic solvent from the organogel. A hydrogel is formed by mixing the xerogel with water or an aqueous solution. A hydrogel encapsulating cells to be cultured may be formed by mixing a xerogel with an aqueous solution containing the cells such as a cell culture solution.Type: GrantFiled: February 28, 2017Date of Patent: February 20, 2024Assignee: SHIMADZU CORPORATIONInventor: Hayato Matsui
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Patent number: 11906475Abstract: In a case where control input is performed via a low-pass filter, a control gain more appropriate for both stability and responsiveness is set according to setting of the low-pass filter. A control unit (21) performs control input for a load mechanism (40) via a low-pass filter, discriminates a stability of a control system including the load mechanism (40) and the low-pass filter when setting of the low-pass filter is changed, sets an appropriate control gain based on a maximum control gain at which an excess amount of a measured value with respect to a target value is equal to or less than a predetermined value within a range where that the control system is stable, and controls an operation of the load mechanism (40) by using the appropriate control gain.Type: GrantFiled: June 25, 2019Date of Patent: February 20, 2024Assignee: SHIMADZU CORPORATIONInventor: Tohru Matsuura
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Patent number: 11906449Abstract: A mass spectrometer (1) includes: an ionization section (201) configured to generate ions from a sample; a mass separation section (231, 235) configured to separate ions generated by the ionization section according to mass-to-charge ratio; an ion detector (237) configured to detect an ion separated by the mass separation section; an ion capture section (31) configured to capture ions separated by the mass separation section; and an electron beam detection section (32) configured to detect an electron beam diffracted by ions captured within the ion capture section (31). This mass spectrometer is capable of performing, in a single measurement operation, both a mass spectrometric analysis and an electron-beam diffraction measurement for distinguishing between isomers. The electron-beam diffraction measurement can be more efficiently performed than in a conventional device of this type.Type: GrantFiled: December 21, 2021Date of Patent: February 20, 2024Assignee: SHIMADZU CORPORATIONInventors: Osamu Furuhashi, Junichi Taniguchi
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Publication number: 20240053357Abstract: An analysis method includes a humidity measurement step of measuring humidity; a binding step of bringing a sample containing an analyte into contact with a carrier to bind the analyte to the carrier; an elution step of bringing the carrier to which the analyte is bound into contact with an eluate containing a volatile organic solvent to elute the analyte into the eluate; a disposition step of disposing the eluate into which the analyte has been eluted on a measurement plate for mass spectrometry; and a detection step of detecting the analyte by mass spectrometry, in which in the elution step, a use amount of the eluate is determined according to the humidity.Type: ApplicationFiled: December 1, 2021Publication date: February 15, 2024Applicant: SHIMADZU CORPORATIONInventor: Naoki KANEKO
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Publication number: 20240053306Abstract: Provided is a quantitative determination method for sulfur compounds in a target group selected from a plurality of groups, e.g., a group including cysteine and related reactive sulfurs, including the steps of: performing an LC/MS/MS measurement of a standard substance having a known concentration of a base compound, e.g.Type: ApplicationFiled: August 4, 2023Publication date: February 15, 2024Applicants: SHIMADZU CORPORATION, Shimadzu Techno-Research, Inc.Inventors: Akihiro KUNISAWA, Atsuhiko TOYAMA, Takaaki AKAIKE, Tsubasa IBUSHI
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Patent number: 11898949Abstract: By irradiating target liquid L containing fine bubbles with ultrasonic waves from an ultrasonic irradiation device 102, the fine bubbles in the target liquid L is reduced. By irradiating the target liquid L with ultrasonic waves, fine bubbles in the target liquid L can be reduced effectively. By using ultrasonic waves, bubbles with small diameters, particularly fine bubbles, can be effectively reduced, so that fine bubbles in the target liquid L can be efficiently reduced.Type: GrantFiled: November 29, 2018Date of Patent: February 13, 2024Assignees: Shimadzu Corporation, National Institute of Technology and Evaluation, Fine Bubble Industries AssociationInventors: Seika Ohuchi, Mitsuru Tanaka, Haruo Shimaoka
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Patent number: 11899030Abstract: A plate changer includes a casing that stores a sample plate and one or a plurality of first rack plates that each support the sample plate. One or a plurality of plate supporters that respectively support the one or plurality of first rack plates at different heights are provided in the casing. Each first rack plate is configured to be supportable on and removable from any of the one or plurality of plate supporters. The plate changer further includes a detector that detects whether the first rack plate is supported on each plate supporter.Type: GrantFiled: November 2, 2018Date of Patent: February 13, 2024Assignee: SHIMADZU CORPORATIONInventors: Kodai Imaeda, Takuya Sawada
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Publication number: 20240044800Abstract: Provided is a microscopic Raman device including: a first laser light source that generates a first laser light; a second laser light source that generates a second laser light having a wavelength different from a wavelength of the first laser light; a first optical element; a second optical element; a third optical element; a fourth optical element; and a spectrometer. When the first laser light is reflected by the first optical element and passes through the third optical element to irradiate a sample, a first Raman scattered light is generated from the sample. When the second laser light is sequentially reflected by the second optical element, the fourth optical element, and the third optical element to irradiate the sample, a second Raman scattered light is generated from the sample. The first Raman scattered light passes through the third optical element and the first optical element to enter the spectrometer.Type: ApplicationFiled: July 27, 2023Publication date: February 8, 2024Applicant: SHIMADZU CORPORATIONInventor: Tomoyo TAO
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Publication number: 20240044810Abstract: In an X-ray imaging, first and second images of X-ray images corresponding to different emission angles are generated. In the X-ray imaging system, based on positions of a target part included in an inspection target in the first and second images, and an angle difference between the emission angles of X-rays that are emitted to generate the first and second images, a three-dimensional position of the target part is calculated by using triangulation.Type: ApplicationFiled: August 3, 2023Publication date: February 8, 2024Applicant: Shimadzu CorporationInventors: Ryuji SAWADA, Hitomi YOSHIYAMA, Hiroaki TSUSHIMA
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Publication number: 20240044847Abstract: Provided is a preparative liquid chromatograph capable of coping with a case where actual second delay time changes after start of a fractionation sequence. When a specific component detected as a peak in both a first detector and a second detector is injected during execution of a fractionation sequence, a control device executes maintenance operation of time difference information stored in an information storage area. In the maintenance operation, the control device executes peak determination as to whether or not a difference between first retention time and second retention time falls within a predetermined allowable range. By the above, the control device checks whether or not the second delay time from when a component is detected by the second detector to when the component reaches a fraction collector changes from a previous state.Type: ApplicationFiled: July 13, 2023Publication date: February 8, 2024Applicant: SHIMADZU CORPORATIONInventors: Soichiro TAMAOKI, Tomoyuki YAMAZAKI, Shohei SATO
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Patent number: 11890126Abstract: A controller (50) is provided with: an orientation determination unit (51) configured to determine an orientation of a subject; a protocol acquisition unit (52); an annotation processing unit (53) configured to perform annotation; a difference determination unit (54) configured to determine whether the currently selected protocol and the orientation of the subject determined by the orientation determination unit (51) are inconsistent with each other; and a warning unit (55) configured to issue a warning and an imaging prohibition unit (56) configured to prohibit imaging when the difference determination unit (54) determines that the currently selected protocol among the protocols acquired by the protocol acquisition unit (52) and the orientation of the subject determined by the orientation determination unit (51) are inconsistent with each other.Type: GrantFiled: March 14, 2019Date of Patent: February 6, 2024Assignee: Shimadzu CorporationInventor: Hiroshi Okumura
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Patent number: 11892434Abstract: In an analyzing system including an analyzing device 10, 20 and a control computer 40, the analyzing device includes: an information input receiver 30 configured to receive an input of information which is encoded in a predetermined format and specifies a method file; and an information sender 23 configured to send the control computer the information received by the information input receiver. The control computer includes: a storage section 413 in which a plurality of method files each describing an analysis condition are stored; a method file locator 423 configured to locate a method file corresponding to the information sent from the information sender among the plurality of method files; an analysis condition setter 424 configured to set an analysis condition of the analyzing device based on the located method file; and an analysis controller 425 configured to control an operation of the analyzing device based on the analysis condition.Type: GrantFiled: November 2, 2020Date of Patent: February 6, 2024Assignee: SHIMADZU CORPORATIONInventor: Yasuhiro Kimoto
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Publication number: 20240038515Abstract: Provided is a mass spectrometer including: a reaction chamber (132) into which a precursor ion is introduced; a radical generation part (54) configured to generate a known radical; a radical supply part (5) configured to react the precursor ion with the radical to generate fragment ions and an adduct ion; a measurement control part (63) configured to measure ions including the precursor ion, the fragment ions, and the adduct ion to obtain a mass spectrum; and an accurate mass estimation part (64) configured to specify a peak of the adduct ion by searching a predetermined mass range centered on a mass value obtained by adding a mass of an atom or molecule derived from the radical to a mass obtained from a peak of the precursor ion, and estimate an accurate mass of the precursor ion by subtracting an accurate mass of the atom or molecule from an accurate mass of the peak.Type: ApplicationFiled: December 23, 2021Publication date: February 1, 2024Applicant: SHIMADZU CORPORATIONInventors: Kazutaka MITSUI, Hidenori TAKAHASHI
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Publication number: 20240037725Abstract: A monitoring device is a monitoring device of a material testing machine including a display having a marker on a display panel. The monitoring device includes: an acquisition unit that acquires a photographed image of a camera that photographs the display panel; a first generation unit that generates a first processed image obtained by gray-scaling the photographed image; a second generation unit that generates a second processed image obtained by performing blur processing on the first processed image; a third generation unit that generates a third processed image obtained by binarizing the first processed image based on the second processed image; and a first detection unit that detects the marker from the third processed image.Type: ApplicationFiled: July 23, 2023Publication date: February 1, 2024Applicant: SHIMADZU CORPORATIONInventor: Tohru MATSUURA
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Patent number: D1014759Type: GrantFiled: June 23, 2022Date of Patent: February 13, 2024Assignee: SHIMADZU CORPORATIONInventor: Ryo Takegawa