Patents Assigned to Sichuan University
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Patent number: 11958781Abstract: The present invention discloses potassium sodium bismuth niobate tantalate zirconate ferrite ceramics with non-stoichiometric Nb5+ and a preparation method therefor. A ceramic powder with a general formula of (K0.45936Na0.51764Bi0.023)(Nb0.89958+0.957xTa0.05742Zr0.04Fe0.003)O3 (?0.01?x?0.04) is prepared by a traditional solid phase method; and then piezoelectric ceramics are prepared by traditional electronic ceramic preparation processes such as granulating, molding, binder removal, sintering and silvering test. An excessive amount of Nb5+ doping improves the temperature stability of the ceramics by providing a domain wall pinning effect. This result demonstrates the promise of potassium sodium bismuth niobate tantalate zirconate ferrite ceramics for a wide range of applications, including sensors, actuators, and other electronic devices.Type: GrantFiled: August 16, 2023Date of Patent: April 16, 2024Assignee: Sichuan UniversityInventors: Jianguo Zhu, Hongjiang Li, Jie Xing, Zhi Tan, Lixu Xie
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Publication number: 20240115226Abstract: The present disclosure is related to systems and methods for medical imaging. The method includes determining a sequence of scan states of a medical device for a sequence of regions of interest (ROIs) of a subject. Each of the sequence of scan states corresponds to an ROI in the sequence of ROIs. When the medical device is in a scan state of the sequence of scan states, an isocenter of the medical device is aligned with a center of the corresponding ROI. The method includes generating a set of controlling information of the medical device based on the sequence of scan states. Each of the set of controlling information is configured to switch the medical device to a corresponding scan state in the sequence of scan states. The method includes controlling the medical device to scan the sequence of ROIs. Before scanning each of the sequence of ROIs, the medical device is positioned to the corresponding scan state according to the corresponding controlling information.Type: ApplicationFiled: December 18, 2023Publication date: April 11, 2024Applicants: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD., WEST CHINA HOSPITAL, SICHUAN UNIVERSITYInventors: Zhenlin LI, Xiaoming WU
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Patent number: 11952402Abstract: A recombinant protein includes a TRAIL domain and an IgG binding domain IgBD. In the recombinant protein, IgBD can be fused at the N-terminus or C-terminus of the TRAIL domain. The anti-tumor effect of the recombinant protein after binding to endogenous or exogenous IgG is significantly stronger than that of TRAIL, and can be used in the treatment of cell proliferative diseases with high expression of death receptors.Type: GrantFiled: August 10, 2020Date of Patent: April 9, 2024Assignee: WEST CHINA HOSPITAL, SICHUAN UNIVERSITYInventors: Xiaofeng Lu, Hao Yang, Ze Tao, Jingqiu Cheng
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Publication number: 20240102496Abstract: A bottom cylinder for a high-temperature and high-pressure environment simulator of a high-fidelity corer is provided. The bottom cylinder includes a cylinder barrel. The bottom of the cylinder barrel is provided with a cylinder base. The piston is provided inside the cylinder barrel and divides an inner cavity of the cylinder barrel into a rodless cavity and a rod cavity. The piston is provided with a piston rod. The outer wall of the cylinder barrel is provided with an oil inlet hole communicated with the rodless cavity, an oil outlet hole communicated with the rod cavity, and a reserved hole. The lower end surface of the piston is provided with a first buffer ring, and the upper surface of the cylinder base is provided with a second buffer ring mated with the first buffer ring. The bottom cylinder is applied to the simulator for oil and gas resource exploitation.Type: ApplicationFiled: August 22, 2022Publication date: March 28, 2024Applicant: SICHUAN UNIVERSITYInventors: Ru ZHANG, Zetian ZHANG, Zhilong ZHANG, Li REN, Chendi LOU, Kun XIAO, Anlin ZHANG, Qijun HAO, Lanbin ZHANG
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Method for Preparing Battery-grade Anhydrous Iron Phosphate from Liquid Crude Monoammonium Phosphate
Publication number: 20240101424Abstract: The present invention provides a method for preparing battery-grade anhydrous iron phosphate from liquid crude monoammonium phosphate, and belongs to the technical field of chemical industry production. In the present invention, ferrous sulfate solution and liquid crude monoammonium phosphate are used as raw materials, and ferrous iron is oxidized to ferric iron and separates out iron phosphate precipitate under the action of an oxidizing agent to obtain iron phosphate intermediate slurry; and then battery-grade anhydrous iron phosphate is finally obtained through solid-liquid separation, washing, aging, solid-liquid separation, washing, drying, dehydration and breaking up. The method provided by the present invention realizes the resource utilization of liquid crude monoammonium phosphate, has simple process and convenient operation and produces less waste water.Type: ApplicationFiled: February 21, 2023Publication date: March 28, 2024Applicant: Sichuan UniversityInventors: Xiaodong Guo, Zhenguo Wu, Yang Song, Tongli Liu, Fa He, Meng Xiao -
Patent number: 11942784Abstract: The present invention discloses a method and device for formulating a coordinated action strategy of SSTS and DVR for voltage sag mitigation. The influence of voltage sag on a whole industrial process of a sensitive user is analyzed, and the sensitive loads of SSTS and DVR which satisfy a governance need are grouped; a practical governance scenario of installing a plurality of DVR is considered to install a minimum-capacity DVR to realize a target of a minimum interruption probability of the whole industrial process of the user; an optimal coordinated governance solution of SSTS and DVR based on sensitive load grouping is proposed; a classification result is obtained for duration time at a time when a voltage sag event occurs through a decision tree constructed based on historical data.Type: GrantFiled: June 24, 2022Date of Patent: March 26, 2024Assignee: Sichuan UniversityInventors: Ying Wang, Man Wang, Xianyong Xiao, Wenxi Hu, Yang Wang, Zixuan Zheng, Yunzhu Chen
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Patent number: 11935326Abstract: A face recognition method based on an evolutionary convolutional neural network is provided. The method optimizes the design of convolutional neural network architecture and the initialization of connection weights by using a genetic algorithm and finds an optimal neural network through continuous evolutionary calculation, thus reducing dependence on artificial experience during the design of the convolutional neural network architecture. The method encodes the convolutional neural networks by using a variable-length genetic encoding algorithm, so as to improve the diversity of structures of convolutional neural networks. Additionally, in order to cross over extended chromosomes, structural units at corresponding positions are separately crossed over and then recombined, thereby realizing the crossover of chromosomes with different lengths.Type: GrantFiled: March 16, 2021Date of Patent: March 19, 2024Assignee: SICHUAN UNIVERSITYInventors: Yanan Sun, Siyi Li
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Publication number: 20240066143Abstract: This invention discloses a natural polyphenols-based, multi-stage porous hydrogel sustained release drug delivery system, which relates to the field of drug delivery. It consists of the hydrogel matrix and the supramolecular filler, which is a complex of natural bio-based polymers and metal ions. The natural bio-based polymer can be natural polyphenols, dopamine or its derivatives, polysaccharide biomass, or protein biomass. The hydrogel matrix can be chitosan, carboxymethyl chitosan, sodium alginate, carboxymethyl cellulose, hyaluronic acid, collagen, gelatin, or agarose. The metal ion can be one of the cations of Al, Fe, Zn, Mn, Ni, Co, or V. By this invention, the supramolecular filler based on natural bio-based polymer can form in situ in the hydrogel, to regulate the pores of the hydrogel and interact with different drugs, thus adjusting the drug release rate.Type: ApplicationFiled: July 3, 2023Publication date: February 29, 2024Applicant: Sichuan UniversityInventors: Junling GUO, Jiaojiao SHANG, Jiezhou PAN
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Patent number: 11912793Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.Type: GrantFiled: April 28, 2023Date of Patent: February 27, 2024Assignee: SICHUAN UNIVERSITYInventors: Ling Ye, Fanyuan Yu, Jiayi Wu, Feifei Li
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Publication number: 20240058111Abstract: An oral cavity restoration space measuring device and method. A depth measuring rod(6) and a main scale(5) are configured to be rigidly connected to each other; a gripping end and a measuring end are connected at a certain angle to reduce a measuring dead angle; a first detachable measuring claw(10) and a second detachable measuring claw(11) are used, and measurements of depth, width and length are integrated; and a digital display meter(4) can rotate around the axis of a connecting rod(9) so as to facilitate the viewing of displayed measurement data.Type: ApplicationFiled: November 29, 2021Publication date: February 22, 2024Applicant: SICHUAN UNIVERSITYInventors: Haiyang Yu, Qin Wu, Chenyang Xie
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Patent number: 11905775Abstract: A driving system for a core drilling rig has a driving motor. The driving motor has an outer rotor and an inner stator, and mutually-matched convex ribs are provided on the inner wall of the outer rotor and the outer wall of the inner stator. The outer rotor and the inner stator are in clearance fit. A clearance between the outer rotor and the inner stator is a driving liquid channel. The length of the outer rotor is less than that of the inner stator. The outer rotor is provided between the front and rear ends of the inner stator. The outer rotor is connected to an outer cylinder. The rear end of the inner stator is connected to a coupling.Type: GrantFiled: November 12, 2018Date of Patent: February 20, 2024Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITYInventors: Mingzhong Gao, Heping Xie, Ling Chen, Jun Guo, Zhilong Zhang, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
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Publication number: 20240016806Abstract: The present disclosure relates to use of a compound in preparation of a medicament for prophylaxis and treatment of inflammatory tissue damage. The present disclosure provides use of a compound in preparation of a medicament for prophylaxis and treatment of tissue damage, and the compound has a structure represented by formula I. The compound having the structure represented by formula I provided by the present disclosure can inhibit transcriptional activity of interferon regulatory factor 1 (IRF1), have prophylactic and therapeutic effects on tissue damage, enhance cell proliferation ability after tissue cell injury, and repair injured tissues. The compound having the structure represented by formula I provided by the present disclosure has important significance and application value in the preparation of the medicament for prophylaxis and treatment of tissue damage, particularly in the preparation of a medicament for inflammatory injuries of skin tissues induced by radiation and/or oxidation.Type: ApplicationFiled: January 18, 2023Publication date: January 18, 2024Applicants: West China Second University Hospital, Sichuan University, Nuclear Industry 416 HospitalInventors: Shuyu Zhang, Fenghao Geng, Jianhui Chen, Xiaoqian Li
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Patent number: 11868432Abstract: A method for extracting a kansei adjective of a product based on principal component analysis and explanation (PCA-E) includes constructing a product kansei evaluation vector matrix through original kansei adjectives; performing dimensionality reduction through PCA; and determining, based on principal component load factors, kansei adjectives representing principal components. In this way, the kansei adjectives extracted are explanatory to help users understand the selected kansei adjectives and make accurate evaluation.Type: GrantFiled: June 2, 2023Date of Patent: January 9, 2024Assignee: SICHUAN UNIVERSITYInventors: Wu Zhao, Xin Guo, Miao Yu, Kai Zhang, Wei Jiang, Chong Jiang, Bing Lai, Yiwei Jiang, Jun Li, Bo Wu, Xingyu Chen
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Publication number: 20240005130Abstract: A method for constructing a design concept generation network (DCGN) and a method for automatically generating a conceptual scheme are provided. A DCGN includes a Transformer encoder, a Transformer decoder, an importance constraint matrix generation module, an importance constraint embedding layer, a cross-attention (CA) layer, and an optimization module. A word importance constraint is ingeniously introduced based on an attention mechanism of a Transformer to record input word constraint information contained in a generated text sequence. This can effectively ensure the reliability and effectiveness of a generated conceptual scheme and is conducive to capturing potential semantic importance information and implementing semantic knowledge reasoning.Type: ApplicationFiled: March 13, 2023Publication date: January 4, 2024Applicant: SICHUAN UNIVERSITYInventors: Wu ZHAO, Miao YU, Xin GUO, Kai ZHANG, Qian ZHAO, Hui YU, Jun LI, Bing LAI, Chong JIANG, Yiwei JIANG, Bo WU, Xingyu CHEN
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Patent number: 11859450Abstract: A drilling fluid channel structure of a core drilling rig includes a fluid channel activation module, a pressure relief module, a flow diverging and blocking module, a driving fluid channel and a cooling fluid channel. The fluid channel activation module, the pressure relief module and the flow diverging and blocking module are connected sequentially from the rear to the front. The driving fluid channel and the cooling fluid channel are connected at the rear side thereof to the flow diverging and blocking module. The driving fluid channel includes a driving section located between a stator and a rotor of a driving motor. The driving fluid channel is provided with a driving fluid outlet at the front side of the driving section. The cooling fluid channel passes through a layer disposed between an integrity-preserving compartment and an outer barrel.Type: GrantFiled: November 12, 2018Date of Patent: January 2, 2024Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITYInventors: Mingzhong Gao, Heping Xie, Ling Chen, Jun Guo, Zhilong Zhang, Zetian Zhang, Ru Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
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Publication number: 20230409671Abstract: A method for extracting a kansei adjective of a product based on principal component analysis and explanation (PCA-E) includes constructing a product kansei evaluation vector matrix through original kansei adjectives; performing dimensionality reduction through PCA; and determining, based on principal component load factors, kansei adjectives representing principal components. In this way, the kansei adjectives extracted are explanatory to help users understand the selected kansei adjectives and make accurate evaluation.Type: ApplicationFiled: June 2, 2023Publication date: December 21, 2023Applicant: SICHUAN UNIVERSITYInventors: Wu ZHAO, Xin GUO, Miao YU, Kai ZHANG, Wei JIANG, Chong JIANG, Bing LAI, Yiwei JIANG, Jun LI, Bo WU, Xingyu CHEN
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Publication number: 20230405111Abstract: The invention belongs to the field of biotechnology, and relates to an allogeneic B cell vaccine against various human-susceptible viruses and a preparation method therefor. The vaccine has anti-tumor and/or anti-viral preventive and/or therapeutic effects. Specifically, the present invention provides a B cell composition, wherein comprising an allogeneic B cell and a virus antigen, the B cell composition is irradiated with a certain dose of ionizing irradiation. The present invention also provides a B cell vaccine, comprising the above B cell composition. The invention also provides a preparation method for the B cell vaccine and a method and system for improving the antigen presentation ability of the B cell.Type: ApplicationFiled: July 12, 2021Publication date: December 21, 2023Applicant: West China Hospital of Sichuan UniversityInventors: Hanshuo YANG, Yuquan WEI
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Patent number: 11844880Abstract: A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.Type: GrantFiled: May 26, 2021Date of Patent: December 19, 2023Assignees: Sichuan University, Shanxi Jinbo Bio-Pharmaceutical Co., LtdInventors: Yunbing Wang, Li Yang, Rifang Luo, Lu Lu, Xia Yang, Xingdong Zhang
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Patent number: 11839705Abstract: An air purification device able to kill bacteria and viruses is provided, including an air channel, an air pump, a filtering device, and an electrodeless ultraviolet sterilization device. The electrodeless ultraviolet sterilization device is arranged inside the air channel and includes a microwave generator, an electrodeless ultraviolet tube, and a uniform radiator. The uniform radiator is a coaxial cable with gaps provided thereon. The electrodeless ultraviolet tube is a hollow columnar quartz tube. The coaxial cable is arranged in a hollow portion of the quartz tube. The coaxial cable is connected to the to microwave generator. The air purification device has a compact structure. Through arranging the electrodeless ultraviolet sterilization device inside the air channel, large-granular dust in the air is filtered, and meanwhile, bacteria and viruses in the air are effectively killed. Moreover, the present invention is safe and effective and has high sterilization efficiency and a low production cost.Type: GrantFiled: February 2, 2021Date of Patent: December 12, 2023Assignee: SICHUAN UNIVERSITYInventors: Huacheng Zhu, Yang Yang, Kama Huang
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Patent number: 11842878Abstract: An injection locked magnetron system based on filament injection is provided, which includes a magnetron, an excitation cavity, and a load. The magnetron is installed on the excitation cavity and connected to the excitation cavity, the excitation cavity is detachably connected to the load, the magnetron is provided with an injection antenna, and the injection antenna is used to receive an injected external signal and couple the injected external signal into the magnetron for realizing injection locking. The injected external signal is injected by a monopole antenna, and coupled into the magnetron resonant cavity through a magnetron filament, and the output microwave of the magnetron is output through the excitation cavity, and passes through the waveguide directional coupler, and is finally absorbed by the load, such that the output microwave of the magnetron can be locked by the injected external signal.Type: GrantFiled: December 13, 2022Date of Patent: December 12, 2023Assignee: Sichuan UniversityInventors: Changjun Liu, Shaoyue Wang, Liping Yan