Patents Assigned to Sichuan University
  • Publication number: 20220332911
    Abstract: A polymer-based spherical powder preparation device and preparation process are disclosed. The preparation device comprises a mill milling system and an inductively coupled plasma powder spheroidization system. The mill milling system of the preparation device can achieve ultra-fine grinding of the material at room temperature by applying strong extrusion, shear and circumferential stress to the material; and the inductively coupled plasma powder spheroidization system using high temperature plasma as high temperature heat source, the polymer powder can be heated uniformly, and the melting and cooling rate is fast, so the spheroidization can be completed in a short time. The preparation process of polymer based spherical powder was integrated and continuously produced by the preparation device.
    Type: Application
    Filed: April 17, 2021
    Publication date: October 20, 2022
    Applicant: Sichuan University
    Inventors: Shibing BAI, Shiping SONG, Yijun LI, Ning CHEN
  • Patent number: 11474201
    Abstract: The present invention discloses a method of controlling transmitting frequencies of microwave source, which includes the following steps of: a) collecting reflection frequencies of a load according to a pre-set sampling rate; b) calculating a change rate of the reflection frequencies collected in the step a; c) setting a reflection frequency threshold and a change rate threshold; d) comparing the reflection frequencies and the change rate with the reflection frequency threshold and the change rate threshold respectively; wherein if the reflection frequencies or the change rate is less than the threshold goes to step e or returns to the step a; e) sending control signals to the microwave source and tuning the transmitting frequencies; and f) returning to step a. The present invention also discloses a microwave transmission system thereof. The present invention can be applied in controlling microwave source consists of single magnetron tube or multiple magnetron tubes.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: October 18, 2022
    Assignee: Sichuan University
    Inventors: Yang Yang, Kama Huang, Xing Chen, Changjun Liu, Huacheng Zhu
  • Publication number: 20220323512
    Abstract: The present disclosure discloses a methicillin-resistant staphylococcus aureus mutant strain and use thereof, and belongs to the field of molecular biology and microorganisms. The methicillin-resistant staphylococcus aureus mutant strain disclosed by the present disclosure has a relatively low exopolysaccharide synthesis ability and a relatively low biofilm metabolism ability, but it is sensitive to an antibiotic cefoxitin. The mutant strain can be used for treating a related disease caused by methicillin-resistant staphylococcus aureus infection through an endogenous ecological treatment strategy. The present disclosure provides a new idea for treating the disease.
    Type: Application
    Filed: February 25, 2022
    Publication date: October 13, 2022
    Applicant: West China Hospital of Sichuan University
    Inventors: Shizhou Wu, Lei Lei, Yunjie Liu
  • Patent number: 11465252
    Abstract: This application relates to lubrication, and more particularly to an external cooling MQL manipulator and a machine tool and a lubrication method using the machine tool. The external cooling MQL manipulator includes a suspension structure, a robot arm, a controller and an oil mist generator. The suspension structure fixedly connects the robot arm and a frame, and a nozzle is provided on a free end of the robot arm; an oil mist generator is connected to the nozzle for ejecting oil mists to a processing area. When the machine tool works, the controller selects the corresponding lubrication parameters according to the processing parameters such as the cutter type and the workpiece material. The first motor and the second motor are controlled to rotate by the controller according to real-time changes of the processing positions detected by the detecting component, thereby adjusting the position of the nozzle.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: October 11, 2022
    Assignee: Sichuan University
    Inventors: Wu Zhao, Zeyuan Yu, Zida Zhang, Ling Chen, Xin Guo, Miao Yu, Kai Zhang, Hao Wan, Lin Du, Wei Jiang, Nianhan Wu
  • Publication number: 20220313896
    Abstract: The present invention discloses a device for removing sputum scabs of a respiratory tract, comprising an outer housing. A fluid hole is designed on a removing part at the front end of the outer housing, and the fluid hole is respectively communicated with a liquid pump and an air pump, so that the device can be extended into the lower respiratory tract of the patient during use. Then, the sputum scabs attached to the inner wall of the respiratory tract can be softened and removed by alternately spraying liquid and gas from the fluid hole, and the removed sputum scabs can be sucked out through negative pressure holes, so as to prevent the scabs of the secretions of the lower respiratory tract from blocking the tracheae.
    Type: Application
    Filed: April 2, 2021
    Publication date: October 6, 2022
    Applicant: West China Hospital of Sichuan University
    Inventor: Xiang TONG
  • Patent number: 11426454
    Abstract: The present invention relates to the field of tuberculosis vaccines, and specifically relates to a tuberculosis vaccine, a preparation method thereof, and a use thereof. To address the problem of existing vaccines being unsuitable for patients having weak immunity, the present invention provides a preparation method for a tuberculosis vaccine: first obtaining Mycobacterium single cell bacteria, and using low dosage radiation to irradiate periodically the Mycobacterium single cell bacteria, so as to obtain the tuberculosis vaccine. The present invention completely retains all of the antigen characteristics of the bacteria, and can more rapidly stimulate stronger specific immune responses, thereby achieving effective and long-lasting immunity. The vaccine prepared using the present invention has low toxicity, is rapid-acting and safer, and can be used for the prevention and treatment of tuberculosis for people having immunodeficiency.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: August 30, 2022
    Assignee: Sichuan University
    Inventors: Zhenling Wang, Yuquan Wei
  • Publication number: 20220215778
    Abstract: A training method for evaluating the bonding accuracy of orthodontic brackets is provided. The evaluation method includes a training device for racket bonding accuracy evaluation which includes virtual teeth with root-shaped connectors and an evaluation base to fix the virtual teeth. Multiple reference lines are marked on the evaluation base, and their intersection is set as the evaluation point. When the virtual tooth is fixed to the evaluation base, the reference lines and the evaluation points are utilized for rapid evaluation of the bonding accuracy of the bracket. Moreover, thanks to their horizontal arrangement, when there are multiple virtual teeth, the evaluation of bracket bonding would be more intuitive and efficient than using the traditional articulator.
    Type: Application
    Filed: December 31, 2021
    Publication date: July 7, 2022
    Applicant: Sichuan University
    Inventors: Chaoran XUE, Peiqi WANG, Bin LI, Ding BAI, Xianglong HAN, Hui XU, Rui SHU, Yongwen GUO, Ye TIAN, Jie FENG, Yating WANG
  • Publication number: 20220180120
    Abstract: A method for generating a human-computer interactive abstract image includes: S1: obtaining and preprocessing the original abstract images used as a training dataset B to obtain edge shape feature maps used as a training dataset A; S2: using the training dataset A and the training dataset B as cycle generative objects of a Cycle-GAN model, and training the Cycle-GAN model to capture a mapping relationship between the edge shape feature maps and the original abstract images; S3: obtaining a line shape image drawn by a user; and S4: according to the mapping relationship, intercepting a generative part in the Cycle-GAN model that the dataset B is generated from the dataset A, discarding a cycle generative part and a discrimination part in the Cycle-GAN model, and generating a complete abstract image based on the line shape image to generate the human-computer interactive abstract image.
    Type: Application
    Filed: April 26, 2021
    Publication date: June 9, 2022
    Applicant: Sichuan University
    Inventors: Jiancheng LV, Youcheng HUANG, Mao LI, Chenwei TANG, Quanhui LIU
  • Publication number: 20220064471
    Abstract: A functional ink suitable for 3D printing and a preparation method thereof are provided. The ink includes the following components in parts by weight: 0.5-1.5 parts of a regulator, 1-5 parts of a conductive material, 0.1-0.5 parts of a crosslinking agent, 0.1-0.5 parts of a catalyst, and 10-80 parts of a solvent. The prepared functional ink has a self-healing function at room temperature, eliminating the interface resistance between printing layers and improving the mechanical strength between the layers. Moreover, the prepared functional ink has excellent electrical conductivity and a variety of electrical, magnetic, and electrochemical properties, and can be applied in the fields of functional materials and devices such as energy storage, electromagnetic shielding and stress sensing.
    Type: Application
    Filed: December 30, 2019
    Publication date: March 3, 2022
    Applicant: Sichuan University
    Inventors: Chuhong ZHANG, Wenbin KANG, Li ZENG, Shangwen LING
  • Patent number: 11218502
    Abstract: A few-shot learning based intrusion detection method of an industrial control system, including: dividing an original data set extracted from a data flow of the industrial control system into a detection model training set and a basic model training set; using principal component analysis method to reduce dimension of a continuous data matrix M in the two training sets; using one-hot encoding method to process a discrete data matrix V in the two training sets; using processed basic model training set to construct few-shot training tasks required for basic model training; training a basic model based on convolutional neural networks with help of constructed few-shot training tasks; based on trained basic model, using processed detection model training set for further training to obtain the detection model; effectively detecting attacks in real-time data streams with help of center vectors of three different types of samples in the detection model.
    Type: Grant
    Filed: June 27, 2021
    Date of Patent: January 4, 2022
    Assignee: Sichuan University
    Inventors: Beibei Li, Tao Li, Yuankai Ouyang, Xiaoxia Ma, Hanyuan Huang, Qingyun Du
  • Publication number: 20210402065
    Abstract: A functionally gradient material for guided periodontal hard and soft tissue regeneration includes a 3D printed scaffold layer and an electrospun fibrous membrane layer. The content of hydroxyapatite in the 3D printed scaffold layer is higher than the content of hydroxyapatite in the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is larger than the pore size of the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is 100-1000 ?m, and the fiber diameter of the electrospun fibrous membrane layer is 300-5000 nm. The electrospun fibrous membrane layer is in a random distribution or an oriented arrangement or has a mesh structure. The thickness of the electrospun fibrous membrane layer is 0.08-1 mm.
    Type: Application
    Filed: July 12, 2019
    Publication date: December 30, 2021
    Applicant: Sichuan University
    Inventors: Jidong LI, Shu'e JIN, Yubao LI, Yi ZUO, Chen YUAN
  • Publication number: 20210369923
    Abstract: A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.
    Type: Application
    Filed: May 26, 2021
    Publication date: December 2, 2021
    Applicants: Sichuan University, Shanxi Jinbo Bio-Pharmaceutical Co., Ltd
    Inventors: Yunbing WANG, Li YANG, Rifang LUO, Lu LU, Xia YANG, Xingdong ZHANG
  • Patent number: 11186526
    Abstract: A method for preparing an organic boron fertilizer for engineering wound soil remediation includes a step of: effectively compounding at least one of chitin oligosaccharide, wormcast and silkworm excrement, at least one of water and hydrogen peroxide, an organic boron element solution, sodium alkyl benzene sulfonate and polysorbate under certain conditions. The present invention has significant effects on improving physical and chemical properties of engineering wound soil, enhancing availability of boron element in the soil, preventing plants from physiological diseases caused by lack of boron, and promoting growth and development of the plants.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: November 30, 2021
    Assignee: Sichuan University
    Inventors: Yingwei Ai, Siqian Yang, Shenghao Ai, Jia Liu, Xiaoyan Ai
  • Patent number: 11180427
    Abstract: A method for preparing an organic complex microelement fertilizer for engineering wound soil remediation includes compounding chitosan oligosaccharide or/and earthworm dung or/and silkworm sand, water or/and hydrogen peroxide, an organic complex trace element solution, polyethylene glycol octyl phenyl ether, and polysorbate under certain conditions. The present invention can significantly improve physical and chemical properties of engineering wounds, enhance effectiveness of trace elements in soil, and prevent plant physiological diseases due to lack of trace elements, and promote plant growth and development.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: November 23, 2021
    Assignee: Sichuan University
    Inventors: Xiaoyan Ai, Yingwei Ai, Xiaoqiao Su, Shenghao Ai, Mengke Zhu
  • Publication number: 20210355371
    Abstract: A viscoelastic surfactant (VES) for a self-diverting acid under high temperature has a structural formula shown as formula (I), wherein, n is saturated hydrocarbon with 2 to 8 carbon atoms; R1 is saturated or unsaturated hydrocarbon with 18 to 28 carbon atoms; R2 and R3 are independently methyl, ethyl or hydrogen, and R2 and R3 can be the same or different; and X? is any one of Cl?, Br?, CO32?, SO42?, HCOO? and CH3COO?. The method for preparing the surfactant includes subjecting a fatty acid and an organic amine to acid-amine condensation to obtain an intermediate. The intermediate reacts with a metal hydride to obtain a fatty amine. Then, an acid solution is used to protonate the fatty amine to obtain an ultra-long-chain viscoelastic cationic surfactant. The present invention also provides use of the surfactant as a thickener for a self-diverting acid.
    Type: Application
    Filed: May 16, 2019
    Publication date: November 18, 2021
    Applicant: Sichuan University
    Inventors: Yujun FENG, Ji WANG, Hongyao YIN
  • Publication number: 20210353262
    Abstract: A method for positioning key features of a lens based on ocular B-mode ultrasound images includes: acquiring and preprocessing the ocular B-mode ultrasound images to obtain a preprocessed B-mode ultrasound image, eyeball coordinates and lens coordinates; sending the preprocessed B-mode ultrasound image, the eyeball coordinates and the lens coordinates into a trained target detection network YOLOv3 to obtain eyeball position images and lens position images; substituting the eyeball position images and the lens position images into a trained feature extraction network group to obtain image features and feature coordinates corresponding to the eyeball position images and the lens position images, respectively; substituting the image features into a trained collaborative learning network to screen key image features; and marking a feature coordinate corresponding to the key image features on the ocular B-mode ultrasound images to complete positioning the key features of the lens.
    Type: Application
    Filed: April 9, 2021
    Publication date: November 18, 2021
    Applicant: Sichuan University
    Inventors: Jiancheng Lv, Yong Wang, Yongsheng Sang, Dezhong Peng, Xi Peng, Yanan Sun, Zhenan He, Qing Ye, Mao Li, Quanhui Liu
  • Publication number: 20210338420
    Abstract: A bioprosthetic valve and a preparation method thereof are provided. The bioprosthetic valve includes a stent and a functional biological tissue material attached to the stent. The functional biological tissue material is a biologicaltissue covalently bonded with an active group and a functional molecule or group. The method improves the anti-thrombosis and anti-calcification functions by covalently modifying the surface of a biological valve using an active group and a functional molecule or group with a substantial degree of grafting. The new bioprosthetic valve does not include aldehyde residues, exhibits excellent biocompatibility, optimal mechanical properties, high stability, and can meet the performance requirements of a biological valve delivered through a catheter.
    Type: Application
    Filed: December 9, 2020
    Publication date: November 4, 2021
    Applicant: Sichuan University
    Inventors: Yunbing Wang, Gaoyang Guo, Li Yang
  • Patent number: 11164682
    Abstract: This disclosure relates to reactor control, and more particularly to a control rod drive mechanism and a reactor control system. The control rod drive mechanism includes a lifting-lowering assembly, a mounting assembly and a release assembly. The mounting assembly is configured to mount a control rod. The lifting-lowering assembly includes a fixing component, a scissor-type lifting-lowering mechanism and a lifting-lowering component. An end of the scissor-type lifting-lowering mechanism is connected to the fixing component, and the other end is connected to the lifting-lowering component. The scissor-type lifting-lowering mechanism is configured to drive the lifting-lowering component to move close to or away from the fixing component. The release assembly is movably arranged on the lifting-lowering component, and is detachably connected to the mounting assembly. The release assembly is configured to move relative to the lifting-lowering component when power is off to release the mounting assembly.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: November 2, 2021
    Assignee: Sichuan University
    Inventors: Wenqiang Li, Hongbiao Sun, Song Li, Wu Zhao, Kai Wang, Zihao Cheng
  • Publication number: 20210336435
    Abstract: A T-type DC circuit breaker includes a main branch, a first commutation switch, a second commutation switch, and a bypass branch. The first commutation switch and the second commutation switch are arranged at both ends of the main branch, respectively. The bypass branch is connected in parallel with the main branch. The main branch includes at least one half-controlled power electronic component. The bypass branch includes a bypass capacitor and a bypass diode connected in series. Each of the first commutation switch and the second commutation switch includes at least one fully-controlled power electronic component. The first commutation switch is connected in parallel with a first surge arrester, and the second commutation switch is connected in parallel with a second surge arrester. The grounded branch is arranged between the main branch and the second commutation switch and is grounded or connected to the negative terminal of the load.
    Type: Application
    Filed: July 15, 2020
    Publication date: October 28, 2021
    Applicant: Sichuan University
    Inventors: Shunliang WANG, Ji SHU, Tianqi LIU, Junpeng MA, Hui PANG, Zhiyuan HE
  • Publication number: 20210322641
    Abstract: An anti-thrombotic and endothelialization-enhanced bioprosthetic valve material and preparation thereof are provided. The preparation method includes the following steps: immersing a glutaraldehyde cross-linked bioprosthetic valve material in functional reagent solution for 1-24 h, adjusting pH value of the solution to 3-8, removing it from solution and cleaning with deionized water. The new valve material of the present invention can effectively reduce the toxicity and side effects of the existing glutaraldehyde cross-linked bioprosthetic valve material and effectively reduce thrombosis, along with enhanced endothelialization. The material prepared can be used for pulmonary valve, aortic valve, mitral valve, tricuspid valve, venous valve and other cardiovascular implantable medical devices.
    Type: Application
    Filed: April 21, 2021
    Publication date: October 21, 2021
    Applicant: Sichuan University
    Inventors: Li YANG, Yunbing WANG, Rifang LUO, Xingdong ZHANG