Patents Assigned to Sichuan University
  • Publication number: 20240261194
    Abstract: A fixing device for double-tube intubation includes a fitting component and a fixing frame arranged on the fitting component, where both ends of the fitting component are connected with a connecting portion, through which the fitting component is fixed to philtrum below nares. The fixing frame includes at least two pressing portions, one side of each of the pressing portions is connected mutually while the other side is mutually and detachably connected, and containing portions for placing the pipeline are arranged between the two pressing portions.
    Type: Application
    Filed: April 22, 2024
    Publication date: August 8, 2024
    Applicants: West China Hospital, Sichuan University, Chengdu Lize Technology Co., Ltd.
    Inventors: Yan JIANG, Yan LIU, Wei CUN, Menghang WU, Hua CAO, Dayong WU, Qijie HUANG
  • Patent number: 12017939
    Abstract: An oily sewage pretreatment method without air flotation, comprising the following steps: (a) sedimentation separation: performing sedimentation separation on oily sewage to implement preliminary separation of oil, sludge, and water; (b) boiling bed separation: performing boiling bed separation on the oily sewage obtained by the preliminary separation to further remove dispersed oil, sludge, and sand from the oily sewage; (c) shape coalescence separation: performing shape coalescence separation on the oily sewage obtained by the boiling bed separation in step (b) to implement demulsification, coalescence, and separation of emulsified oil; and (d) biochemical treatment: the effluent obtained in step (c) directly enters an AOH biochemical system, an air flotation unit is omitted. Also disclosed is an oily sewage pretreatment apparatus without air flotation.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: June 25, 2024
    Assignees: Shanghai Huachang Environmental Protection Co., Ltd., Sichuan University, East China University of Science and Technology
    Inventors: Hualin Wang, Yuxiao Sun, Jiandong Hu, Yi Liu, Huiqing Yu, Haiyang Bai, Bichuan Yu, Dun Wang, Xia Jiang, Zhishan Bai, Qiang Yang, Jianqi Chen, Wei Yuan, Qisong Shen
  • Patent number: 12017937
    Abstract: Disclosed is a rotational flow rotation deoiling method for oil-based mud rock debris.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: June 25, 2024
    Assignees: Shanghai Huachang Environmental Protection Co., Ltd., Sichuan University, East China University of Science and Technology
    Inventors: Jiwei Wu, Hualin Wang, Jiake Pan, Xia Jiang, Lixiang Wang, Yuan Huang, Jianping Li, Pengbo Fu, Wenjie Lv
  • Patent number: 12009676
    Abstract: A SWIPT (simultaneous wireless information and power transfer) device based on the modulation of power supply ripple of magnetron includes a magnetron power supply, a magnetron, an IF (intermediate frequency) signal generator and a first capacitor. The first and second cathode power lines are provided between two ends of the magnetron power supply and two ends of the cathode of the magnetron respectively. One end of the first capacitor is connected with the IF signal generator, and another end of the first capacitor is connected with the first cathode power line. A SWIPT method includes applying an IF signal which is equivalent to the ripple of anode voltage of the magnetron to the anode voltage of the magnetron; taking a resonance signal excited by the magnetron as a local oscillation signal; generating a new signal at an output end of the magnetron, and radiating the new signal through an antenna.
    Type: Grant
    Filed: October 12, 2022
    Date of Patent: June 11, 2024
    Assignee: Sichuan University
    Inventors: Yang Yang, Huacheng Zhu
  • Patent number: 11998239
    Abstract: A puncture instrument kit includes a puncture rod, mesh, and sheath. The puncture rod consists of a puncture head, puncture rod body, and handle. One end of the puncture rod body is connected to the handle and the other end is integrated with the puncture head. The puncture head is arc-shaped with an end gradually tapering to form a tip. The tip of the puncture head is circumferentially designed with a groove for fixing a thread during surgery. The puncture head is smoothly connected with the puncture rod body, and the line between the tip of the puncture head and puncture rod body is at an obtuse angle of 130-140° relative to the puncture rod body. The sheath is sleeved on the puncture rod with the rod tip exposed. The mesh and sheath are designed as separate or integrated, and the tip of the puncture rod is provided with a shape-matching detachable silicone protective sleeve.
    Type: Grant
    Filed: March 10, 2023
    Date of Patent: June 4, 2024
    Assignee: West China Hospital of Sichuan University
    Inventors: Deyi Luo, Hong Shen, Chi Zhang, Xiao Zeng
  • Patent number: 11958781
    Abstract: The present invention discloses potassium sodium bismuth niobate tantalate zirconate ferrite ceramics with non-stoichiometric Nb5+ and a preparation method therefor. A ceramic powder with a general formula of (K0.45936Na0.51764Bi0.023)(Nb0.89958+0.957xTa0.05742Zr0.04Fe0.003)O3 (?0.01?x?0.04) is prepared by a traditional solid phase method; and then piezoelectric ceramics are prepared by traditional electronic ceramic preparation processes such as granulating, molding, binder removal, sintering and silvering test. An excessive amount of Nb5+ doping improves the temperature stability of the ceramics by providing a domain wall pinning effect. This result demonstrates the promise of potassium sodium bismuth niobate tantalate zirconate ferrite ceramics for a wide range of applications, including sensors, actuators, and other electronic devices.
    Type: Grant
    Filed: August 16, 2023
    Date of Patent: April 16, 2024
    Assignee: Sichuan University
    Inventors: Jianguo Zhu, Hongjiang Li, Jie Xing, Zhi Tan, Lixu Xie
  • Publication number: 20240101424
    Abstract: The present invention provides a method for preparing battery-grade anhydrous iron phosphate from liquid crude monoammonium phosphate, and belongs to the technical field of chemical industry production. In the present invention, ferrous sulfate solution and liquid crude monoammonium phosphate are used as raw materials, and ferrous iron is oxidized to ferric iron and separates out iron phosphate precipitate under the action of an oxidizing agent to obtain iron phosphate intermediate slurry; and then battery-grade anhydrous iron phosphate is finally obtained through solid-liquid separation, washing, aging, solid-liquid separation, washing, drying, dehydration and breaking up. The method provided by the present invention realizes the resource utilization of liquid crude monoammonium phosphate, has simple process and convenient operation and produces less waste water.
    Type: Application
    Filed: February 21, 2023
    Publication date: March 28, 2024
    Applicant: Sichuan University
    Inventors: Xiaodong Guo, Zhenguo Wu, Yang Song, Tongli Liu, Fa He, Meng Xiao
  • Patent number: 11942784
    Abstract: The present invention discloses a method and device for formulating a coordinated action strategy of SSTS and DVR for voltage sag mitigation. The influence of voltage sag on a whole industrial process of a sensitive user is analyzed, and the sensitive loads of SSTS and DVR which satisfy a governance need are grouped; a practical governance scenario of installing a plurality of DVR is considered to install a minimum-capacity DVR to realize a target of a minimum interruption probability of the whole industrial process of the user; an optimal coordinated governance solution of SSTS and DVR based on sensitive load grouping is proposed; a classification result is obtained for duration time at a time when a voltage sag event occurs through a decision tree constructed based on historical data.
    Type: Grant
    Filed: June 24, 2022
    Date of Patent: March 26, 2024
    Assignee: Sichuan University
    Inventors: Ying Wang, Man Wang, Xianyong Xiao, Wenxi Hu, Yang Wang, Zixuan Zheng, Yunzhu Chen
  • Publication number: 20240066143
    Abstract: This invention discloses a natural polyphenols-based, multi-stage porous hydrogel sustained release drug delivery system, which relates to the field of drug delivery. It consists of the hydrogel matrix and the supramolecular filler, which is a complex of natural bio-based polymers and metal ions. The natural bio-based polymer can be natural polyphenols, dopamine or its derivatives, polysaccharide biomass, or protein biomass. The hydrogel matrix can be chitosan, carboxymethyl chitosan, sodium alginate, carboxymethyl cellulose, hyaluronic acid, collagen, gelatin, or agarose. The metal ion can be one of the cations of Al, Fe, Zn, Mn, Ni, Co, or V. By this invention, the supramolecular filler based on natural bio-based polymer can form in situ in the hydrogel, to regulate the pores of the hydrogel and interact with different drugs, thus adjusting the drug release rate.
    Type: Application
    Filed: July 3, 2023
    Publication date: February 29, 2024
    Applicant: Sichuan University
    Inventors: Junling GUO, Jiaojiao SHANG, Jiezhou PAN
  • Publication number: 20240016806
    Abstract: The present disclosure relates to use of a compound in preparation of a medicament for prophylaxis and treatment of inflammatory tissue damage. The present disclosure provides use of a compound in preparation of a medicament for prophylaxis and treatment of tissue damage, and the compound has a structure represented by formula I. The compound having the structure represented by formula I provided by the present disclosure can inhibit transcriptional activity of interferon regulatory factor 1 (IRF1), have prophylactic and therapeutic effects on tissue damage, enhance cell proliferation ability after tissue cell injury, and repair injured tissues. The compound having the structure represented by formula I provided by the present disclosure has important significance and application value in the preparation of the medicament for prophylaxis and treatment of tissue damage, particularly in the preparation of a medicament for inflammatory injuries of skin tissues induced by radiation and/or oxidation.
    Type: Application
    Filed: January 18, 2023
    Publication date: January 18, 2024
    Applicants: West China Second University Hospital, Sichuan University, Nuclear Industry 416 Hospital
    Inventors: Shuyu Zhang, Fenghao Geng, Jianhui Chen, Xiaoqian Li
  • Publication number: 20230405111
    Abstract: The invention belongs to the field of biotechnology, and relates to an allogeneic B cell vaccine against various human-susceptible viruses and a preparation method therefor. The vaccine has anti-tumor and/or anti-viral preventive and/or therapeutic effects. Specifically, the present invention provides a B cell composition, wherein comprising an allogeneic B cell and a virus antigen, the B cell composition is irradiated with a certain dose of ionizing irradiation. The present invention also provides a B cell vaccine, comprising the above B cell composition. The invention also provides a preparation method for the B cell vaccine and a method and system for improving the antigen presentation ability of the B cell.
    Type: Application
    Filed: July 12, 2021
    Publication date: December 21, 2023
    Applicant: West China Hospital of Sichuan University
    Inventors: Hanshuo YANG, Yuquan WEI
  • Patent number: 11844880
    Abstract: A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: December 19, 2023
    Assignees: Sichuan University, Shanxi Jinbo Bio-Pharmaceutical Co., Ltd
    Inventors: Yunbing Wang, Li Yang, Rifang Luo, Lu Lu, Xia Yang, Xingdong Zhang
  • Patent number: 11842878
    Abstract: An injection locked magnetron system based on filament injection is provided, which includes a magnetron, an excitation cavity, and a load. The magnetron is installed on the excitation cavity and connected to the excitation cavity, the excitation cavity is detachably connected to the load, the magnetron is provided with an injection antenna, and the injection antenna is used to receive an injected external signal and couple the injected external signal into the magnetron for realizing injection locking. The injected external signal is injected by a monopole antenna, and coupled into the magnetron resonant cavity through a magnetron filament, and the output microwave of the magnetron is output through the excitation cavity, and passes through the waveguide directional coupler, and is finally absorbed by the load, such that the output microwave of the magnetron can be locked by the injected external signal.
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: December 12, 2023
    Assignee: Sichuan University
    Inventors: Changjun Liu, Shaoyue Wang, Liping Yan
  • Patent number: 11828324
    Abstract: A quick-detachable connecting device with a simplified thread structure includes a top nozzle, a connecting tube sleeve, a locking tube and a locking piece. The top nozzle is provided with a through hole, in which the connecting tube sleeve is assembled. The locking tube is accommodated in the through hole. An outer peripheral surface of the locking tube is provided with a second stopping structure, and an inner peripheral surface of the connecting tube sleeve is provided with a first stopping structure fitting the second stopping structure. The locking piece is movably arranged on the locking tube for circumferentially limiting or releasing the locking tube. A connection method using such connecting device is also provided.
    Type: Grant
    Filed: August 24, 2023
    Date of Patent: November 28, 2023
    Assignee: Sichuan University
    Inventors: Wenqiang Li, Yingdong Liu, Hai Xiang, Jiahao Chen, Yingxin Zhao, Jiawei Wang
  • Publication number: 20230374545
    Abstract: The disclosure in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the disclosure relates to gene transfer methods using the recombinant adeno-associated viruses. In some aspects, the disclosure relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same.
    Type: Application
    Filed: January 5, 2023
    Publication date: November 23, 2023
    Applicants: University of Massachusetts, Sichuan University
    Inventors: Guangping Gao, Guangchao Xu, Phillip Tai, Yuquan Wei, Li Luo
  • Patent number: 11816403
    Abstract: The present invention discloses a method for designing an orthognathic surgical occlusal plate based on artificial intelligence, including scanning a gypsum model of the maxillary and mandibular dentition to obtain the corresponding three-dimensional model of the maxillary and mandibular dentition; then obtaining the fitting data and establishing a coordinate system; generating thickness control elements and two-dimensional contour lines; controlling thickness of the three-dimensional model and generating occlusal imprint: and modifying the thickness and occlusal imprint of the three-dimensional model to obtain an artificial intelligence occlusal plate. The invention can greatly save the time required for designing the occlusal plate, improve the work efficiency, and the accuracy of the artificial orthognathic surgery occlusal plate is not significantly different from that of the manual occlusal plate in the application of orthognathic surgery.
    Type: Grant
    Filed: November 28, 2022
    Date of Patent: November 14, 2023
    Assignee: Sichuan University
    Inventors: En Luo, Zhao Kun Zhu, Zhikai Liu, Chunwei Xu, Yao Liu, Yue Tai, Zhen Liu
  • Publication number: 20230310548
    Abstract: The present invention provides a use of IFN-? in preparing an anti-tumor adjuvant drug, wherein the IFN-? enhances killing effect of the T cell preparation on tumor cell by sensitizing the tumor cell; the T cell preparation comprises non-genetically engineered T cell and/or genetically engineered T cell; and the IFN-? comprises full-length or fragment of wild-type or mutant IFN-?. The present invention revises the current understanding of IFN-? in the prior art and finds that the IFN-? inhibits the acquired immune resistance mediated by PD-L1-PD-1 and enhances the anti-tumor effect of immunotherapy by activating the IFN-? signaling pathway in tumor cell.
    Type: Application
    Filed: March 3, 2021
    Publication date: October 5, 2023
    Applicant: West China Hospital of Sichuan University
    Inventors: Hanshuo YANG, E. DONG, Xiaozhu YUE
  • Patent number: 11772091
    Abstract: The present disclosure relates to a method and an apparatus for treating, sorting and recycling an oil-containing discharged catalyst. There is provided a method for treating, sorting and recycling an oil-containing discharged catalyst, wherein the method comprises the following steps: (A) cyclonic washing and on-line activation of a discharged catalyst; (B) cyclonic spinning solvent stripping of the catalyst; (C) gas stream acceleration sorting of a high activity catalyst; (D) cyclonic restriping and particle capture of the high activity catalyst; and (E) cooling of the gas and condensation removal of the solvent. There is further provided an apparatus for treating, sorting and recycling an oil-containing discharged catalyst.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: October 3, 2023
    Assignees: Shanghai Huachang Environmental Protection Co., Ltd, Sichuan University
    Inventors: Hualin Wang, Pengbo Fu, Zhaohui Huang, Aibin Huang, Cheng Huang, Jianhuai Sun, Ying Zhao, Liquan Li, Chonggang Chen, Qian Zeng, Jianping Li, Yilin Fang, Fei Wang, Xia Jiang
  • Publication number: 20230285051
    Abstract: A puncture instrument kit includes a puncture rod, mesh, and sheath. The puncture rod consists of a puncture head, puncture rod body, and handle. One end of the puncture rod body is connected to the handle and the other end is integrated with the puncture head. The puncture head is arc-shaped with an end gradually tapering to form a tip. The tip of the puncture head is circumferentially designed with a groove for fixing a thread during surgery. The puncture head is smoothly connected with the puncture rod body, and the line between the tip of the puncture head and puncture rod body is at an obtuse angle of 130-140° relative to the puncture rod body. The sheath is sleeved on the puncture rod with the rod tip exposed. The mesh and sheath are designed as separate or integrated, and the tip of the puncture rod is provided with a shape-matching detachable silicone protective sleeve.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 14, 2023
    Applicant: West China Hospital of Sichuan University
    Inventors: Deyi LUO, Hong SHEN, Chi ZHANG, Xiao ZENG
  • Patent number: 11734389
    Abstract: A method for generating a human-computer interactive abstract image includes: S1: obtaining and preprocessing the original abstract images used as a training dataset B to obtain edge shape feature maps used as a training dataset A; S2: using the training dataset A and the training dataset B as cycle generative objects of a Cycle-GAN model, and training the Cycle-GAN model to capture a mapping relationship between the edge shape feature maps and the original abstract images; S3: obtaining a line shape image drawn by a user; and S4: according to the mapping relationship, intercepting a generative part in the Cycle-GAN model that the dataset B is generated from the dataset A, discarding a cycle generative part and a discrimination part in the Cycle-GAN model, and generating a complete abstract image based on the line shape image to generate the human-computer interactive abstract image.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: August 22, 2023
    Assignee: Sichuan University
    Inventors: Jiancheng Lv, Youcheng Huang, Mao Li, Chenwei Tang, Quanhui Liu