Patents Assigned to Sichuan University
  • Patent number: 11842878
    Abstract: An injection locked magnetron system based on filament injection is provided, which includes a magnetron, an excitation cavity, and a load. The magnetron is installed on the excitation cavity and connected to the excitation cavity, the excitation cavity is detachably connected to the load, the magnetron is provided with an injection antenna, and the injection antenna is used to receive an injected external signal and couple the injected external signal into the magnetron for realizing injection locking. The injected external signal is injected by a monopole antenna, and coupled into the magnetron resonant cavity through a magnetron filament, and the output microwave of the magnetron is output through the excitation cavity, and passes through the waveguide directional coupler, and is finally absorbed by the load, such that the output microwave of the magnetron can be locked by the injected external signal.
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: December 12, 2023
    Assignee: Sichuan University
    Inventors: Changjun Liu, Shaoyue Wang, Liping Yan
  • Patent number: 11834360
    Abstract: An integrated device and method for treating toxic and refractory wastewater are provided. The integrated device includes an adjusting pool, a first-stage reactor, a second-stage reactor, a third-stage reactor, a coagulation sedimentation pool, and a biochemical reaction pool that are sequentially connected in series, and further includes an aeration blower. Each of the first-stage reactor and the third-stage reactor is an advanced oxidation reactor, and the second-stage reactor is a Fenton reactor. The coagulation sedimentation pool includes 2 to 4 stages, and each stage of the coagulation sedimentation pool includes a coagulation tank, a primary sedimentation tank, and a secondary sedimentation tank that are connected in series. The biochemical reaction pool includes an anoxic tank, an aerobic tank, a settling tank, and a clean water tank that are connected in series.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: December 5, 2023
    Assignee: SICHUAN UNIVERSITY
    Inventors: Bo Lai, Heng Zhang, Yang Liu, Zhaokun Xiong, Chuanshu He
  • Patent number: 11834724
    Abstract: A light-colored polycarboxylated polysaccharide tanning agent, and a preparation method and use thereof are provided. The light-colored polycarboxylated polysaccharide tanning agent includes the following raw materials: a polysaccharide, an organic solvent, a catalyst, and hydrogen peroxide. Based on a weight of the polysaccharide, a weight of the organic solvent accounts for 1 wt % to 15 wt %, a weight of the catalyst accounts for 0.05 wt % to 2 wt %, and a weight of the hydrogen peroxide accounts for 30 wt % to 80 wt %. The preparation method provided by the present disclosure adopts a two-phase solution system. Compared with the existing preparation technologies, the preparation method of the present disclosure can efficiently extract and remove colored substances produced during an oxidation process, and can timely block a polymerization reaction of the colored substances with an oxidized polysaccharide, such as to significantly reduce a chromaticity of an oxidized product.
    Type: Grant
    Filed: March 7, 2022
    Date of Patent: December 5, 2023
    Assignee: SICHUAN UNIVERSITY
    Inventors: Yue Yu, Yanan Wang, Bi Shi, Xueru Guo, Jianfei Zhou, Yunhang Zeng, Wenhua Zhang, Mingrong Cao
  • Publication number: 20230383629
    Abstract: A high-temperature and high-pressure simulator for a deep in-situ environment is provided. The simulator includes a high-fidelity sample chamber, where a lower end of the high-fidelity sample chamber is provided with a bottom cylinder. A lower end of the bottom cylinder is provided on a base. A piston rod of the bottom cylinder extends into the high-fidelity sample chamber, and an upper end of the piston rod is provided with a rock sample seat. An upper end of the high-fidelity sample chamber is provided with a rock sample cap. The top of the high-fidelity sample chamber is sealed by an end cap of the high-fidelity sample chamber. An upper end of the end cap of the high-fidelity sample chamber is provided with a multi-section coring drill chamber. The uppermost section of the coring drill chamber is connected to a lift cylinder.
    Type: Application
    Filed: August 22, 2022
    Publication date: November 30, 2023
    Applicant: SICHUAN UNIVERSITY
    Inventors: Ru ZHANG, Heping XIE, Zetian ZHANG, Li REN, Zhilong ZHANG, Yihang LI, Weiqiang LING, Heng GAO
  • Patent number: 11828324
    Abstract: A quick-detachable connecting device with a simplified thread structure includes a top nozzle, a connecting tube sleeve, a locking tube and a locking piece. The top nozzle is provided with a through hole, in which the connecting tube sleeve is assembled. The locking tube is accommodated in the through hole. An outer peripheral surface of the locking tube is provided with a second stopping structure, and an inner peripheral surface of the connecting tube sleeve is provided with a first stopping structure fitting the second stopping structure. The locking piece is movably arranged on the locking tube for circumferentially limiting or releasing the locking tube. A connection method using such connecting device is also provided.
    Type: Grant
    Filed: August 24, 2023
    Date of Patent: November 28, 2023
    Assignee: Sichuan University
    Inventors: Wenqiang Li, Yingdong Liu, Hai Xiang, Jiahao Chen, Yingxin Zhao, Jiawei Wang
  • Publication number: 20230374545
    Abstract: The disclosure in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the disclosure relates to gene transfer methods using the recombinant adeno-associated viruses. In some aspects, the disclosure relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same.
    Type: Application
    Filed: January 5, 2023
    Publication date: November 23, 2023
    Applicants: University of Massachusetts, Sichuan University
    Inventors: Guangping Gao, Guangchao Xu, Phillip Tai, Yuquan Wei, Li Luo
  • Patent number: 11821274
    Abstract: A moon-based in-situ condition-preserved coring multi-stage large-depth drilling system and method therefor. The system includes a rotary plate provided inside a lander, an in-situ condition-preserved coring tool provided on a surface of the rotary plate, a space frame provided on a surface of the rotary plate, a working platform provided on a top of the space frame, a mechanical arm provided on a bottom surface of the working platform, and a camera provided on the bottom surface of the working platform, the mechanical arm is fixedly connected to the working platform, and the camera is fixedly connected to the working platform. By controlling the mechanical arm to place the in-situ condition-preserved coring tool on the moon surface, and using the in-situ condition-preserved coring tool to sample the lunar soil on the moon surface, the coring operation problem of the lunar soil is solved.
    Type: Grant
    Filed: July 5, 2019
    Date of Patent: November 21, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Heping Xie, Mingzhong Gao, Ling Chen, Guoqing Zhang, Jianan Li, Jianbo Zhu, Cunbao Li
  • Patent number: 11816403
    Abstract: The present invention discloses a method for designing an orthognathic surgical occlusal plate based on artificial intelligence, including scanning a gypsum model of the maxillary and mandibular dentition to obtain the corresponding three-dimensional model of the maxillary and mandibular dentition; then obtaining the fitting data and establishing a coordinate system; generating thickness control elements and two-dimensional contour lines; controlling thickness of the three-dimensional model and generating occlusal imprint: and modifying the thickness and occlusal imprint of the three-dimensional model to obtain an artificial intelligence occlusal plate. The invention can greatly save the time required for designing the occlusal plate, improve the work efficiency, and the accuracy of the artificial orthognathic surgery occlusal plate is not significantly different from that of the manual occlusal plate in the application of orthognathic surgery.
    Type: Grant
    Filed: November 28, 2022
    Date of Patent: November 14, 2023
    Assignee: Sichuan University
    Inventors: En Luo, Zhao Kun Zhu, Zhikai Liu, Chunwei Xu, Yao Liu, Yue Tai, Zhen Liu
  • Publication number: 20230357321
    Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.
    Type: Application
    Filed: April 28, 2023
    Publication date: November 9, 2023
    Applicant: SICHUAN UNIVERSITY
    Inventors: Ling Ye, Fanyuan Yu, Jiayi Wu, Feifei Li
  • Patent number: 11788371
    Abstract: A coring device has core drilling tool, a core catcher, a rock core barrel, a drilling machine outer cylinder, a flap valve and an inner rod for pulling the rock core barrel. The core catcher is provided inside the lower end of the rock core barrel. The core drilling tool includes an outer core tube and a hollow drill bit. The upper end of the outer core tube is connected to the lower end of the drilling machine outer cylinder. The lower end of the outer core tube is connected to the drill bit. The lower end of the inner rod protrudes into the rock core barrel and is movable axially by a certain distance relative to the rock core barrel. The flap valve includes a valve seat and a sealing flap. The valve seat is coaxially mounted on the inner wall of the drilling machine outer cylinder.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 17, 2023
    Assignee: SHENZHEN UNIVERSITY SICHUAN UNIVERSITY
    Inventors: Heping Xie, Mingzhong Gao, Ling Chen, Zhiyi Liao, Zhilong Zhang, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11788370
    Abstract: A drilling control mechanism of a core drilling rig has a tooth drill and a core drilling rig. The core drilling rig is inside the tooth drill and engages with the drill in a sliding manner. A locking recess is formed at an inner wall of the tooth drill. A locking latch recess is formed at an outer wall of the core drilling rig and has a locking latch therein. The locking latch has a spring. When the locking recess is directly opposite the locking latch recess, the spring extends and the locking latch partially enters the locking recess. The core drilling rig has a central rod, a fluid channel activation module, an outer barrel, and outer barrel unlocking module and a flow diverging module. The central rod passes through the inner cavities of the fluid channel activation module, the outer barrel unlocking module and the flow diverging module.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 17, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Mingzhong Gao, Ling Chen, Heping Xie, Zhilong Zhang, Jun Guo, Zetian Zhang, Ru Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11781382
    Abstract: A drilling mechanism of a coring drilling rig has a central rod, a fluid channel starting module, an outer barrel, an outer barrel unlocking module, a flow diverging module and a drill bit. The central rod penetrates the fluid channel starting module. The outer barrel unlocking module and an inner cavity of the flow diverging module from back to front. The fluid channel starting module is behind the outer barrel and is connected to the outer barrel unlocking module. The flow diverging module is in front of the outer barrel unlocking module, and a hydraulic motor is connected in front of the flow diverging module. The outer barrel has a driving section that is a rotor of the hydraulic motor. The outer wall of the outer barrel is fixedly connected to a centralizer, and the front end of the outer barrel is connected to the drill bit.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 10, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Mingzhong Gao, Heping Xie, Ling Chen, Zhilong Zhang, Jun Guo, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Publication number: 20230310548
    Abstract: The present invention provides a use of IFN-? in preparing an anti-tumor adjuvant drug, wherein the IFN-? enhances killing effect of the T cell preparation on tumor cell by sensitizing the tumor cell; the T cell preparation comprises non-genetically engineered T cell and/or genetically engineered T cell; and the IFN-? comprises full-length or fragment of wild-type or mutant IFN-?. The present invention revises the current understanding of IFN-? in the prior art and finds that the IFN-? inhibits the acquired immune resistance mediated by PD-L1-PD-1 and enhances the anti-tumor effect of immunotherapy by activating the IFN-? signaling pathway in tumor cell.
    Type: Application
    Filed: March 3, 2021
    Publication date: October 5, 2023
    Applicant: West China Hospital of Sichuan University
    Inventors: Hanshuo YANG, E. DONG, Xiaozhu YUE
  • Patent number: 11772091
    Abstract: The present disclosure relates to a method and an apparatus for treating, sorting and recycling an oil-containing discharged catalyst. There is provided a method for treating, sorting and recycling an oil-containing discharged catalyst, wherein the method comprises the following steps: (A) cyclonic washing and on-line activation of a discharged catalyst; (B) cyclonic spinning solvent stripping of the catalyst; (C) gas stream acceleration sorting of a high activity catalyst; (D) cyclonic restriping and particle capture of the high activity catalyst; and (E) cooling of the gas and condensation removal of the solvent. There is further provided an apparatus for treating, sorting and recycling an oil-containing discharged catalyst.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: October 3, 2023
    Assignees: Shanghai Huachang Environmental Protection Co., Ltd, Sichuan University
    Inventors: Hualin Wang, Pengbo Fu, Zhaohui Huang, Aibin Huang, Cheng Huang, Jianhuai Sun, Ying Zhao, Liquan Li, Chonggang Chen, Qian Zeng, Jianping Li, Yilin Fang, Fei Wang, Xia Jiang
  • Patent number: 11773673
    Abstract: A coring drill tool driving structure has a driving motor (7), an outer cylinder (23) and a coring drill tool (8). The driving motor comprises an outer rotor (73) and an inner stator (75), the inner wall of the outer rotor and the outer wall of the inner stator are provided with ribs (77) mutually matched, the outer rotor and inner stator are in clearance fit, the clearance between the outer rotor and the inner stator is a driving liquid flow path (74), the outer rotor length is smaller than the inner stator length, the outer rotor is located between front and rear ends of the inner stator, the outer rotor is connected to the outer cylinder, a front end of the outer cylinder is connected to the coring drill tool, and a rear end of the inner stator is connected to a coupling (76).
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 3, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Heping Xie, Mingzhong Gao, Ling Chen, Zhilong Zhang, Jun Guo, Zetian Zhang, Ru Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Patent number: 11774380
    Abstract: A diffraction analysis device and a method for a full-field X-ray fluorescence imaging analysis are disclosed. The device includes a switching assembly, collimation assemblies, an X-ray source, an X-ray detector, a laser indicator, and a computer control system. The switching assembly combines with the collimation assemblies to achieve a functional effect that is previously achieved by two different types of devices through only one device by changing the positioning layout of the X-ray source and the X-ray detector. The full-field X-ray fluorescence imaging analysis can be realized, and the crystal phase composition information and the element distribution imaging information of the sample can be quickly obtained through the same device without scanning, which not only greatly improves the utilization rate of each assembly in the device, reduces the assemblies cost of the device, makes the device structure more compact, but also greatly improves the analysis efficiency and detection accuracy.
    Type: Grant
    Filed: February 8, 2023
    Date of Patent: October 3, 2023
    Assignee: SICHUAN UNIVERSITY
    Inventors: Yuanjun Xu, Ze He, Peng Wang, Ning Huang, Zhu An
  • Patent number: 11773670
    Abstract: A control mechanism of a core drilling rig includes a central rod (14) and an outer barrel (23). The central rod (14) passes through, from the rear to the front, the inner cavities of a fluid channel activation module, an outer barrel unlocking module, a flow diverging module, and a coring barrel connecting module. The coring barrel connecting module comprises a core tube connecting pipe (62), a core ring bearing (63), a bearing inner ring (64), a ball A (6211) and a ball B (6411). The core tube connecting pipe (62) is connected at the front side thereof to the coring barrel (65). The bearing inner ring (64) is inside the core tube connecting pipe (62). The core ring bearing (63) is connected to an inner wall of the outer barrel (23).
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: October 3, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Mingzhong Gao, Heping Xie, Ling Chen, Jun Guo, Zhilong Zhang, Zetian Zhang, Ru Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Publication number: 20230305050
    Abstract: A state estimation method for a multi-stage voltage sag comprises analyzing characteristics of multi-stage voltage sags due to different causes. A method for determining the cause of sudden change time of an amplitude of the multi-stage voltage sag is based on a jump characteristic of the sag amplitude. Calculation methods of a relay protection action matrix and a faulty line set are utilized to preliminarily obtain a faulty line set based on the fault clearing time of a relay protection device and other characteristics to effectively reduce a calculation amount of sag state estimation. Based on a substantive characteristic that different events cause a change of system impedance, a method for inferring a cause of an event in each stage of the multi-stage voltage sag is used to improve the accuracy of the state estimation. The state estimation method reduces the difficulty in applying to the multi-stage voltage sag.
    Type: Application
    Filed: December 16, 2022
    Publication date: September 28, 2023
    Applicant: SICHUAN UNIVERSITY
    Inventors: Ying WANG, Haishan HE, Xianyong XIAO, Wengxi HU, Yunzhu CHEN
  • Patent number: 11761283
    Abstract: A core barrel sealing structure includes a core barrel, a drilling machine outer barrel, a chain mail-type flap valve and a trigger mechanism. The flap valve includes a valve seat and a chain mail-type valve flap. The trigger mechanism includes a trigger inner barrel and a trigger block. The trigger block is arranged in a through hole in a sidewall of the trigger inner barrel, and an inner wall of the drilling machine outer barrel is provided with a recessed opening adapted to the trigger block. When the core barrel is located in the valve seat, the valve flap is opened by 90° and is located between the trigger inner barrel and the drilling machine outer barrel. When the core barrel is lifted upwards, the valve flap returns to a top face of the valve seat to make sealing contact with a sealing face of a valve opening.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: September 19, 2023
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Heping Xie, Ling Chen, Mingzhong Gao, Jun Guo, Zhilong Zhang, Zetian Zhang, Yiqiang Lu, Cong Li, Zhiqiang He
  • Publication number: 20230285051
    Abstract: A puncture instrument kit includes a puncture rod, mesh, and sheath. The puncture rod consists of a puncture head, puncture rod body, and handle. One end of the puncture rod body is connected to the handle and the other end is integrated with the puncture head. The puncture head is arc-shaped with an end gradually tapering to form a tip. The tip of the puncture head is circumferentially designed with a groove for fixing a thread during surgery. The puncture head is smoothly connected with the puncture rod body, and the line between the tip of the puncture head and puncture rod body is at an obtuse angle of 130-140° relative to the puncture rod body. The sheath is sleeved on the puncture rod with the rod tip exposed. The mesh and sheath are designed as separate or integrated, and the tip of the puncture rod is provided with a shape-matching detachable silicone protective sleeve.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 14, 2023
    Applicant: West China Hospital of Sichuan University
    Inventors: Deyi LUO, Hong SHEN, Chi ZHANG, Xiao ZENG