Patents Assigned to Sichuan University
  • Publication number: 20200266722
    Abstract: A dynamic stability analysis and control method for a voltage sourced converter based high voltage direct current (VSC-HVDC) transmission system. The method includes the following steps: unlocking a converter station of the VSC-HVDC transmission system to make the VSC-HVDC transmission system run in a non-island control mode; extracting corresponding parameters of the VSC-HVDC transmission system, wherein the parameters include an effective voltage value Ut0 of an AC system, an outgoing reactive power Qvsc0 of the VSC-HVDC transmission system, a gain kp of a phase-locked loop (PLL), and a proportional integral time constant ki of the PLL; calculating a short-circuit ratio (SCR), an unit value of Ut0 and an unit value of Qvsc0; calculating a key stable component; checking the sign of the key stable component to determine the stability of the VSC-HVDC transmission system.
    Type: Application
    Filed: February 14, 2020
    Publication date: August 20, 2020
    Applicant: Sichuan University
    Inventors: Baohong LI, Tianqi LIU, Yan TAO, Shunliang WANG
  • Patent number: 10745989
    Abstract: The present disclosure relates to the field of scientific drilling technologies, and provides a deep rock in-situ active thermal-insulation coring device and thermal-insulation coring method thereof. The coring device comprises an in-situ coring system and an in-situ truth-preserving moving system, the in-situ coring system comprises a driving module, a coring module and a thermal insulation module, and the in-situ truth-preserving moving system comprises a truth-preserving chamber storage module and a mechanical arm; the thermal insulation module comprises a coring truth-preserving chamber and a temperature regulation control system, the truth-preserving chamber storage module comprises a storage truth-preserving chamber and a temperature balance control system, the mechanical arm is mounted in the storage truth-preserving chamber, and the coring truth-preserving chamber and the storage truth-preserving chamber are mutually butted.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: August 18, 2020
    Assignees: SHENZHEN UNIVERSITY, SICHUAN UNIVERSITY
    Inventors: Heping Xie, Ling Chen, Mingzhong Gao, Cunbao Li, Guangdi Deng, Xia Hua
  • Patent number: 10744528
    Abstract: Disclosed is an adjustable ultrasonic micro-jet nozzle array with minimal quantity lubrication, relating to cooling of machining. The array-type nozzle includes an inlet conduit, a recycle conduit and a cooling body having a microjet ejection assembly and a recycling assembly. The cooling body includes a microjet ejection chamber which is closed. The inlet conduit is provided at a top of the cooling body and communicates with the microjet ejection chamber. The recycle conduit is located in the microjet ejection chamber, and connects the recycling assembly and an external vacuum machine. The adjustable ultrasonic micro jet nozzle array of the present invention has the advantages of simple structure and being convenient to use. A flow rate of trace cooling fluid is increased to improve the cooling and lubricating effect. A cooling fluid mist is recycled by the vacuum suction to reduce the consumption of the lubricating fluid while ensuring the cooling effect.
    Type: Grant
    Filed: November 17, 2019
    Date of Patent: August 18, 2020
    Assignee: Sichuan University
    Inventors: Ling Chen, Wu Zhao, Wei Jiang, Hao Wan, Qianmiao Zhou, Xin Guo, Miao Yu, Kai Zhang, Lin Du, Zeyuan Yu, Nianhan Wu
  • Publication number: 20200232950
    Abstract: A system for monitoring rock damage in deep engineering environment includes an acoustic emission sensor assembly and an acoustic emission amplifier assembly. The assemblies are mounted on a rock mechanics test system. The acoustic emission sensor clamp includes a coupling screw, as well as a clamp cover, a clamp cylinder, and a coupling panel threadedly connected in sequence. The acoustic emission amplifier assembly includes an acoustic emission amplifier, an upright column having a guide rail, a lifting support plate, and a support plate lifting oil cylinder. Additionally, an evaluation method based on acoustic emission tempo-spatial evolution laws is presented. According to the properties of acoustic emission, fractal characteristics of damage evolution processes of rock test pieces are analyzed and the relationship between stress, energy and fractal dimension in the whole process of tensile deformation damage of the rock test pieces is obtained.
    Type: Application
    Filed: March 30, 2020
    Publication date: July 23, 2020
    Applicants: Sichuan University, Chengdu University
    Inventors: Huining XU, Jianfeng LIU, Yan WAN, Jianliang PEI, Lu WANG, Chunping WANG, Qiangxing ZHANG
  • Publication number: 20200217821
    Abstract: A tempo-spatial evolution test system for rock breaking in deep and complex environment includes an acoustic emission sensor assembly and an acoustic emission amplifier assembly that are arranged on a rock mechanics test system. A triaxial cavity coupling bracket is arranged on an outer wall of the triaxial cavity and between two sets of acoustic emission sensor assemblies. The triaxial cavity coupling bracket includes a plate-shaped bracket, two sickle-shaped brackets, and at least three bracket bolts, which can be tightly wrapped on the outer wall of the triaxial cavity. A lateral side of the plate-shaped bracket vertically fixes two guide columns. The acoustic emission amplifier assembly is arranged between the two guide columns and is located above the plate-shaped bracket, and the acoustic emission amplifier assembly is connected to the acoustic emission sensor assembly through a signal line.
    Type: Application
    Filed: November 29, 2019
    Publication date: July 9, 2020
    Applicants: Sichuan University, Chengdu University
    Inventors: Jianfeng LIU, Yan WAN, Jun ZHENG, Lu WANG, Dongjie XUE, Chunping WANG, Qiangxing ZHANG
  • Patent number: 10704998
    Abstract: The invention belongs to the field of rock mechanics test of engineering rock masses and is intended to address the safety and alignment challenges of a rock mechanics test response system for existing simulated complex deep earth environment. A rock mechanics test response system for a simulated complex deep earth environment includes a bearing system for rock mechanics tests in simulated deep earth environment and an MTS triaxial sensor aligning and mounting device arranged on the bearing system for rock mechanics tests in simulated deep earth environment. The invention improves installation and dismounting efficiency of an MTS triaxial force sensor, enhances reliability of lifting and solves the problem of aligning holes during installation of the force sensor, thus improving the installation efficiency.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: July 7, 2020
    Assignee: SICHUAN UNIVERSITY
    Inventors: Jianfeng Liu, Heping Xie, Huining Xu, Jianliang Pei, Chunping Wang, Jianhui Deng, Wenxi Fu, Lu Wang
  • Patent number: 10682439
    Abstract: A three-dimensional porous polyurethane scaffold for repairing central nerve injuries and a preparation method are disclosed. The scaffold includes three-dimensional porous polyurethane, wherein the compression modulus of the three-dimensional porous polyurethane is 0.001-10.0 MPa and the pore diameter is 10-200 ?m. The three-dimensional porous polyurethane scaffold has an efficient central nerve repair function without additionally inoculating functional cells or factors and can partially restore the original nerve function of tested animals, the preparation method is simple and it has a great prospect of application.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: June 16, 2020
    Assignee: SICHUAN UNIVERSITY
    Inventors: Hong Tan, Fang Fang, Jiehua Li, Yanchao Wang, Yingke Wu, Qiang Fu, Feng Luo
  • Patent number: 10611771
    Abstract: The present invention discloses pyrazolo[3,4-d]pyrimidine derivatives of formula (I). Compounds provided in the present invention have significant inhibitory effects on tumor cells, can be used for the prevention and/or treatment of tumor-related diseases, especially lung cancer, and have wide application prospects.
    Type: Grant
    Filed: August 16, 2016
    Date of Patent: April 7, 2020
    Assignee: WEST CHINA HOSPITAL, SICHUAN UNIVERSITY
    Inventors: Yang He, Weimin Li, Li Zhang, Bojiang Chen, Zhixin Qiu
  • Publication number: 20200069583
    Abstract: An in situ phase change gel sustained-release preparation for a small molecule drug and a preparation method thereof. The in situ phase change gel sustained-release preparation comprises a small molecule drug comprising an active pharmaceutical ingredient, a phospholipid, Span, and an ethanol solution. The in situ phase change gel sustained-release preparation has a high concentration of phospholipids combined with Span, and is thus able to reduce the immediate-release of the small molecule drug and extend the release time, and is suitable for various administration routes, such as subcutaneous injection and external administration.
    Type: Application
    Filed: October 11, 2017
    Publication date: March 5, 2020
    Applicants: SICHUAN UNIVERSITY, YAOPHARMA CO., LTD.
    Inventors: Tao GONG, Xu SONG, Zhirong ZHANG, Yan ZHANG, Guangfei WEI, Mei HU, Tijia CHEN, Xun SUN, Yao FU
  • Publication number: 20200057023
    Abstract: An electronic integrated multi-electrode detection system of a potential determination includes a multi-electrode array, a circuit unit and a total signal output and acquisition unit. The circuit unit includes a multi-electrode array signal input end, a high input impedance voltage follower, a phase shifting filter circuit, an extension module input end, a summing circuit and a total output signal end. The detection system promotes the detection sensitivity and increase the accuracy and precision of detection results. The detection system can be used for monitoring the change in trace ion concentration in a sample, analyzing a constant conventional sample and analyzing a sample with higher error requirement. The detection system can be widely applied to various analysis detection fields, including life sciences, environmental sciences, medicine clinics, and the like.
    Type: Application
    Filed: February 11, 2018
    Publication date: February 20, 2020
    Applicant: SICHUAN UNIVERSITY
    Inventors: Dan XIAO, Chunling WANG, Hongyan YUAN, Zhijuan DUAN
  • Patent number: 10563205
    Abstract: This invention discloses a nucleic acid aptamer AS1411 modified DNA tetrahedron. The preparation method includes the steps of (1) binding an AS1411 sequence to the 5? terminal of any DNA single-strand in a DNA tetrahedron, synthesizing the DNA, dissolving obtained DNA powder with ddH2O; (2) measuring an absorbance of the DNA and then calculating a total volume of the four single strands; (3) pipetting the DNA obtained in step (1) according to the calculation results in step (2), mixing the DNA with a TM buffer, mixing the mixture uniformly with vortex vibration, and performing a PCR progress. The preparation method is simple. The produced product can effectively solve the problem that the unmodified DNA tetrahedron cannot enter the nucleus and the problem that the AS1411 cannot carry drugs directly.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: February 18, 2020
    Assignee: SICHUAN UNIVERSITY
    Inventors: Yunfeng Lin, Qianshun Li, Xiaoxiao Cai, Shiyu Lin, Xiaoru Shao
  • Patent number: 10558805
    Abstract: A method of detecting malware in Linux platform through the following steps: use objdump-D command to disassemble ELF format benign software and malware samples to generate assembly files; traverse the generated assembly files one by one, read the ELF files' code segment and meanwhile identify whether the code segment contains main( ) function; analyze the code segment read. Divide assembly code into different basic blocks. Each basic block is marked by its lowest address. Add control flow graph's vertex to the adjacency linked list; establish the relation between basic blocks, add control flow graph's edges to the adjacency linked list and generate a basic control flow graph; extract control flow graph's features and write them into ARFF files; take ARFF files as the data set of a machine learning tool named weka to carry out data mining and construct classifier; classify the ELF samples to be tested by using the classifier.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: February 11, 2020
    Assignees: SICHUAN UNIVERSITY, Beijing Tongtech Co., LTD.
    Inventors: Junfeng Wang, Baoxin Xu, Dong Liu, Fan Li, Xiaosong Zhang
  • Publication number: 20200033361
    Abstract: The present disclosure relates to the technical field of comparative proteomics, in particular to a detection and quantitation method for proteomics of post-translational modifications. With this method, the protein samples to be studied and internal standards are labeled with isobaric tandem mass tags, and tandem mass spectrometry analysis is carried out for the labeled peptide mixture, wherein the internal standard is a peptide mixture rich in post-translational modifications to be detected. Through this method, the signal of peptides containing the post-translational modifications to be detected can be amplified under the situation that mass spectrometer sensitivity is unchanged, and enrichment of the post-translational modification peptides is not needed. The probability of detecting the peptides containing the post-translational modifications to be detected by mass spectrometer and being selected for subsequent MS/MS analysis is increased.
    Type: Application
    Filed: September 19, 2019
    Publication date: January 30, 2020
    Applicant: Sichuan University
    Inventor: Lunzhi DAI
  • Patent number: 10526714
    Abstract: Disclosed are a method and device for using CO2 mineralization to produce sodium bicarbonate or sodium carbonate and output electric energy. The device comprises an anode area, an intermediate area, and a cathode area. The anode area and the intermediate area are spaced by a negative ion exchange membrane (2). The intermediate area and the cathode area are spaced by a positive ion exchange membrane (3). The anode area, the intermediate area, and the cathode area can accommodate corresponding electrolytes. An anode electrode (1) is disposed in the anode area, a cathode electrode (4) is disposed in the cathode area, and the cathode electrode and the anode electrode are connected through a circuit. A raw material hydrogen gas inlet is disposed in the anode area, and a CO2 inlet and a product hydrogen gas outlet are disposed in the cathode area.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: January 7, 2020
    Assignee: SICHUAN UNIVERSITY
    Inventors: Heping Xie, Yifei Wang, Tao Liu, Jinlong Wang
  • Patent number: 10507246
    Abstract: This invention discloses a method for preparing TDNs-AS1411-nucleic acid drug nanocomposite based drug delivery system, which includes the following steps: binding AS1411 and nucleic acid drug to a tetrahedral DNA nanostructure respectively; selecting four DNA single strands that respectively carry AS1411 and nucleic acid drug; mixing the four DNA single strands; mixing the DNA single strands and the TM buffer uniformly; putting the mixture into a PCR apparatus; raising the temperature to 95° C. quickly and maintaining for 10 min; and next cooling down to 4° C. and maintaining for 20 min to obtain the TDNs-AS1411-nucleic acid drug nanocomposite based drug delivery system. This drug delivery system can directly act on cell nucleus and will not be degraded by lysosomal. The targeting specificity is good. The drug can take a good efficacy and the pertinency is high.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: December 17, 2019
    Assignee: Sichuan University
    Inventors: Yunfeng Lin, Sirong Shi, Xiaoxiao Cai, Shiyu Lin, Qianshun LI
  • Patent number: 10506747
    Abstract: A mouse for magnetic resonance, comprising an upper shell (1), a lower shell (2), a trackball (3), a circuit board (4) and a cable (5), wherein the inner surfaces of the upper shell (1) and the lower shell (2) are coated with a silver and copper conductive paint layer, the concentration of a silver and copper conductive paint being 13% to 17%; and a manufacturing method for the mouse for magnetic resonance, and a signal transmission apparatus are further comprised. The clinical usage of functional magnetic resonance can be satisfied, a signal interference is avoided, and it is ensured that a remote computer accurately receives a response of a subject.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: December 10, 2019
    Assignee: WEST CHINA HOSPITAL, SICHUAN UNIVERSITY
    Inventors: Qiyong Gong, Huaiqiang Sun, Lefeng Ren, Haoyang Xing, Jie Tang, Xiaoqi Huang, Youjin Zhao
  • Patent number: 10470257
    Abstract: The present invention relates to a technical field of microwave heating, and more particularly to a microwave frequency-selective heating device and a method thereof. The microwave frequency-selective heating device includes: a heating chamber with a microwave feed-in device, and a frequency controller; wherein the frequency controller is connected to the microwave feed-in device. According to the microwave frequency-selective heating device and the method of the present invention, the heating frequency is adjusted by setting the microwave adjusting device, which improves a material heating uniformity while greatly increases a material microwave absorption rate, so as to solve a heating efficiency problem of the conventional technologies. According to the present invention, the frequency for the heated material is intelligently selected by the micro-processor of the microwave adjusting device, and then fed in after being adjusted by the frequency control circuit, which is effective and convenient.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: November 5, 2019
    Assignee: Sichuan University
    Inventors: Kama Huang, Huacheng Zhu, Yang Yang, Changjun Liu, Xing Chen
  • Publication number: 20190331566
    Abstract: A bearing system for rock mechanics test under high temperature and high pressure multi-field coupling includes a force sensor lifting seat and a jack. The force sensor lifting seat includes a connecting disk connected with the jack, a support disk, and an operation channel. A groove dented downwards is arranged on the connecting disk, the support disk is disposed in the groove and freely propped upon the connecting disk; through holes of the connecting disk and the support disk form a control operation channel; and a limiting device is arranged for preventing an MTS triaxial force sensor from disengaging from the support disk. A bolt hole of the force sensor can be aligned with a mounting hole on a solid steel column by rotating the connecting disk for convenient and accurate bolting.
    Type: Application
    Filed: April 28, 2019
    Publication date: October 31, 2019
    Applicant: Sichuan University
    Inventors: Jianfeng LIU, Heping XIE, Jianliang PEI, Lu WANG, Wenxi FU, Xiaozhang LEI, Dongjie XUE, Yufeng WEI
  • Publication number: 20190331568
    Abstract: A triaxial high temperature and high pressure rock mechanics load test platform includes a base, a lifting seat, and an intermediate connecting seat arranged between the base and the lifting seat. A hydraulic assembly is arranged between the base and the intermediate connecting seat; the intermediate connecting seat is connected with the lifting seat by means of a group of connecting rods; the lifting seat is enclosed by a side wall and a base plate to form a receiving groove with an upward opening; and a limiting device is arranged on the side wall of the lifting seat for preventing an MTS triaxial force sensor from disengaging from a support disk.
    Type: Application
    Filed: April 29, 2019
    Publication date: October 31, 2019
    Applicant: Sichuan University
    Inventors: Jianfeng LIU, Xiaozhang LEI, Wenxi FU, Feng DAI, Yufeng WEI, Chunping WANG, Huining XU, Jianliang PEI, Fei WU, Gang CHEN, Jinbing WEI
  • Publication number: 20190331567
    Abstract: A loading platform for a rock mechanics test system (MTS) to realize simple and reliable connection between a high temperature and high pressure force sensor in a triaxial chamber cavity and an upper solid rigid column. The loading platform for rock mechanics test includes a master rod, a secondary rod and a stop sleeve sleeved on the master rod; the stop sleeve is provided with two corbel structures; the secondary rod is composed of a secondary rod head body and a secondary rod body; a circular magnetic block is fixed on the secondary rod to adsorb a hole alignment sleeve sleeved on the secondary rod; and the hole alignment sleeve marked with a first scale line and a second scale line.
    Type: Application
    Filed: April 29, 2019
    Publication date: October 31, 2019
    Applicants: Chengdu University of Technology, Sichuan University
    Inventors: Yufeng WEI, Jianfeng LIU, Lu WANG, Huining XU, Xiaozhang LEI, Jianhui DENG, Dongjie XUE, Chunping WANG, Jianliang PEI, Wenxi FU, Da ZHENG