Abstract: The disclosure provides a new method for preparing a WPU synthetic leather foaming layer based on a Pickering foam template method. The key of the method is to use the soft waterborne polyurethane as raw materials, add waterborne crosslinking agent and hydrophobic inorganic solid particles as Pickering waterborne foam stabilizers to obtain Pickering waterborne foam slurry of polyurethane latex particles through high-speed emulsification; and dry the slurry to obtain the waterborne polyurethane foam layer. The preparation process does not use any organic solvents, is clean and environmentally-friendly, and is simple to operate, making it easier to realize industrialized production. In addition, the Pickering foam has strong interface stability, which effectively solves the problem of difficult adjustment of the pore size caused by the accumulation and collapse of bubbles during the drying process of the mechanical foaming method, and the prepared synthetic leather foam layer has good hygienic properties.

Abstract: A urinary system catheter is covered by an ethanol extract of propolis on a surface of the urinary system catheter. The EEP is used as a coating material of the urinary system catheter to prepare an antimicrobial urinary system catheter. The EEP serving as a surface coating can enhance surface hydrophilicity of the urinary system catheter, and clinical operation of the urinary system catheter is facilitated. Meanwhile, the EEP serving as the surface coating can prevent a bacterial biofilm from being formed on the surface of the urinary system catheter, thereby possessing antimicrobial and anti-infective effects, and a high anti-scab capacity. In addition, propolis is a natural substance, has the advantages of good biocompatibility and low cost, and is suitable for mass production. The urinary system catheter prepared by using the EEP as the coating has a good application prospect.

Abstract: A system for monitoring internal corrosion of a pipeline based on radio-frequency identification (RFID), including a magnetizing device, a RFID tag sensor, and a reader. The magnetizing device is placed on the pipeline, and includes an armature, a first permanent magnet, a first pole shoe, a second permanent magnet and a second pole shoe. The RFID tag sensor is placed on the pipeline, and at the same side with the magnetizing device. The reader is in wireless communication connection with the RFID tag sensor through a reader antenna.

Abstract: A method for differentiable architecture search based on a hierarchical grouping mechanism includes: obtaining a target dataset; selecting a set number of normal cells and two reduction cells; enabling the reduction cells to be located at ? and ? of all cells, respectively, and then concatenating all cells to form an initial search network; training the initial search network to optimize a cost function to complete a one-level search or a two-level search, wherein in the one-level search, control weight parameters are shared by the inter-group operations and are shared by the intra-group operations among the cells; and in the two-level search, the control weight parameters are shared by the inter-group operations and are not shared by the intra-group operations, obtaining normal cells and reduction cells based on the one-level search or the two-level search; and constructing a target network using the normal cells and the reduction cells.

Abstract: A soot-suppression flame-separation combustion device for combustion calorimetry and in-situ free radicals monitoring is mainly composed of a premixed combustion gas guide tube, an inner flame generating seat, an oxidation flame separation guide, and a sample combustion chamber. The inner flame generating seat is arranged in the premixed combustion gas guide tube, the oxidation flame separation guide is arranged on the premixed combustion gas guide outlet end of the premixed combustion gas guide tube, the sample combustion chamber is a cavity arranged inside the oxidation flame separation guide, and the oxidation flame separation guide is evenly arranged with at least 4 oxidation flame separation guide paths in a manner of surrounding the sample combustion chamber. The combustion device utilizes the special structure of the oxidation flame separation guide to suppress the generation of smoke and limit the smoke particles to a specific combustion area.

Abstract: A microwave heating device with reflection protection belongs to a technical field of microwave applications. A first port of a circulator is connected to a microwave generator, and a second port of the circulator is connected to a microwave transmission device. A water load comprises a waveguide section, a metamaterial structure layer and the absorption tube. One end of the waveguide section is connected to a third port of the circulator, and the other end is sealed by a metal plate. The metamaterial structure layer is arranged in the waveguide section, and a center of the metamaterial structure layer has an accommodation space. The absorption tube is arranged along an internal wall of the accommodation space with a spiral extending form. Both ends of the absorption tube penetrate the waveguide section, and coolant flows in the absorption tube. Relative dielectric constants of the metamaterial structure layer gradually increase.

Abstract: A method and system for strategically solving an innovative design problem are provided. A target analysis tool is determined according to a to-be-solved problem. An initial model is generated based on the target analysis tool. A target model is determined according to an interaction relationship among elements in the initial model and the target analysis tool. A problem characterization result of the target model is generated according to a preset interaction relationship. Retrieval information is generated according to the problem characterization result, based on which the retrieval is performed in a preset database to obtain target data. Different analysis tools can be used to analyze different to-be-solved problems. The retrieval is performed based on the problem characterization result to obtain the solution to the to-be-solved problem.

Abstract: A soot-suppression flame-separation combustion device for combustion calorimetry and in-situ free radicals monitoring is mainly composed of a premixed combustion gas guide tube, an inner flame generating seat, an oxidation flame separation guide, and a sample combustion chamber. The inner flame generating seat is arranged in the premixed combustion gas guide tube, the oxidation flame separation guide is arranged on the premixed combustion gas guide outlet end of the premixed combustion gas guide tube, the sample combustion chamber is a cavity arranged inside the oxidation flame separation guide, and the oxidation flame separation guide is evenly arranged with at least 4 oxidation flame separation guide paths in a manner of surrounding the sample combustion chamber. The combustion device utilizes the special structure of the oxidation flame separation guide to suppress the generation of smoke and limit the smoke particles to a specific combustion area.

Abstract: A surgical instrument includes an end effector assembly configured to apply ultrasonic energy or electrosurgical energy to a tissue. The end effector assembly includes an ultrasonic blade configured to transmit ultrasonic vibration to the tissue and a clamp arm assembly, where the clamp arm assembly is configured to be operatively pivoted towards or away from the ultrasonic blade, and includes a clamp pad arranged adjacent to the ultrasonic blade and configured to compress or transect the tissue clamped therebetween; a first electrode arranged at a side of the clamp pad away from the ultrasonic blade and configured to apply the electrosurgical energy to the tissue; and an insulative support member pivotally coupled to the transmission assembly and configured to support the clamp pad and the first electrode.

Abstract: The disclosure relates to the field of underground salt cavern energy storage, and discloses a coupling numerical simulation method for site selection of an underground salt cavern hydrogen storage, which specifically comprises the following. Geological data of an area where the salt cavern hydrogen storage is to be established is obtained. A three-dimensional model is established and grid meshing is performed. An initial coupling field is established and balanced based on the geological model, and then excavation simulation of the salt cavern hydrogen storage is performed. A geological model after excavation and related parameter values thereof are imported into TOUGH2MP software, a stress model in FLAC3D software is coupled with hydraulic and thermal models in the TOUGH2MP software to simulate a stress, hydraulic, and thermal coupling behavior process of rock layers around the salt cavern hydrogen storage in the area, and a coupled simulation result is obtained.

Abstract: The present invention provides a method for preparing battery-grade anhydrous iron phosphate from liquid crude monoammonium phosphate, and belongs to the technical field of chemical industry production. In the present invention, ferrous sulfate solution and liquid crude monoammonium phosphate are used as raw materials, and ferrous iron is oxidized to ferric iron and separates out iron phosphate precipitate under the action of an oxidizing agent to obtain iron phosphate intermediate slurry; and then battery-grade anhydrous iron phosphate is finally obtained through solid-liquid separation, washing, aging, solid-liquid separation, washing, drying, dehydration and breaking up. The method provided by the present invention realizes the resource utilization of liquid crude monoammonium phosphate, has simple process and convenient operation and produces less waste water.

Abstract: Disclosed are a corona-resistant N-grade insulation paper for a variable frequency motor and a preparation method thereof. The insulation paper has a sandwich structure, aramid nanofibers and mica nanosheets are taken as a sandwich material of the sandwich structure, aramid nanofibers and silicon carbide nanowires being taken as upper and lower surface layer materials, and three layers of materials are electrostatically sprayed and thermo-compressed to prepare the insulation paper. According to the present disclosure, by introducing mica sheets and the silicon carbide nanowires into the aramid nanofibers, the highly ordered arrangement inside the sandwich structure is realized through electrostatic spraying, which improves the temperature resistance and corona resistance of the insulation paper.

Abstract: The present invention relates to the field of bioengineering, and in particular to a chimeric antigen receptor (CAR) expression vector and use thereof. The CAR expression vector comprising a polynucleotide encoding a CAR and full length or fragment of a polynucleotide encoding a granulocyte-macrophage colony-stimulating factor (GM-CSF). The CAR-GM-T cell constructed by the present invention is capable of expressing high-level GM-CSF, not only directly enhancing killing activity of the CAR-GM-T cell per se but also facilitating the infiltration of the CAR-GM-T cell into a solid tumor. The CAR-GM-T cell has a stronger immune modulation function compared to the conventional CAR-T cell and systematically triggers the endogenous anti-tumor immune response, thereby achieving superior therapeutic efficacy against a solid tumor.

Abstract: A method for preparing a pre-loadable biological heart valve capable of rapid rehydration includes performing a cross-linking treatment, wherein a biological valve is cross-linked by soaking in an aqueous glutaraldehyde solution; performing a hydrophilic treatment, wherein the biological valve is soaked in a solution containing a hydrophilic molecule and a condensing agent, to allow the hydrophilic molecule to be immobilized on the biological valve by chemical grafting; and performing a drying treatment, wherein the biological valve after the hydrophilic treatment and the cross-linking treatment is dried to obtain the pre-loadable biological heart valve capable of rapid rehydration.

Abstract: This application relates to a bifunctional and flexible hydrogel optical fiber, a preparation method and an application thereof. Raw materials of a fiber core include polyethylene glycol diacrylate (PEGDA), methacrylamide, 2-hydroxyethyl methacrylate (HEMA) and 2,2-diethoxy-phenylacetophenone (DMPA); raw materials of an intermediate fiber layer include Synechococcus cells, PEGDA, gelatin methacrylate (GelMA), anhydrous strontium chloride and DMPA; and raw materials of a cladding include PEGDA, methacrylamide, sodium alginate and DMPA. A continuous and controllable direct oxygen supply function is provided through an optical fiber structure.

Abstract: A bioprosthetic valve and a preparation method thereof are provided. The bioprosthetic valve includes a stent and a functional biological tissue material attached to the stent. The functional biological tissue material is a biologicaltissue covalently bonded with an active group and a functional molecule or group. The method improves the anti-thrombosis and anti-calcification functions by covalently modifying the surface of a biological valve using an active group and a functional molecule or group with a substantial degree of grafting. The new bioprosthetic valve does not include aldehyde residues, exhibits excellent biocompatibility, optimal mechanical properties, high stability, and can meet the performance requirements of a biological valve delivered through a catheter.

Abstract: The disclosure relates to the field of underground salt cavern energy storage, and discloses a coupling numerical simulation method for site selection of an underground salt cavern hydrogen storage, which specifically comprises the following. Geological data of an area where the salt cavern hydrogen storage is to be established is obtained. A three-dimensional model is established and grid meshing is performed. An initial coupling field is established and balanced based on the geological model, and then excavation simulation of the salt cavern hydrogen storage is performed. A geological model after excavation and related parameter values thereof are imported into TOUGH2MP software, a stress model in FLAC3D software is coupled with hydraulic and thermal models in the TOUGH2MP software to simulate a stress, hydraulic, and thermal coupling behavior process of rock layers around the salt cavern hydrogen storage in the area, and a coupled simulation result is obtained.

Abstract: A pre-loadable dried biological heart valve and a preparation method thereof. The preparation method includes: Step A: soaking a fresh animal pericardium in an aqueous solution of soluble elastin or glycosaminoglycan, and then subjecting the pericardium to a first cross-linking reaction in a mixed solution of carbodiimide or N-hydroxysuccinimide to allow the soluble elastin or glycosaminoglycan to bind to the pericardium via a chemical bond; and Step B: subjecting the pericardium after the first cross-linking to a second cross-linking reaction in an aqueous glutaraldehyde solution, and then drying the pericardium after the second cross-linking, to obtain the pre-loadable dried biological heart valve. The dried biological heart valve obtained by the above preparation method has good toughness, and is rapidly flattened out in a simulated folding and pressing test.

Abstract: The present disclosure provides a method for improving a biological nitrogen removal effect of low-temperature sewage, and relates to the technical field of sewage treatment. In the present disclosure, the method is implemented by adding an exogenous signal molecule. The exogenous signal molecule can intervene in a quorum sensing (QS) phenomenon among microorganisms, and can also reduce mixed liquor suspended solids (MLSS), reduce an amount of remaining sludge, and reduce a cost of sludge treatment while effectively improving the low-temperature nitrogen removal effect.

Abstract: The present invention belongs to the field of biomedicine, and particularly relates to a chimeric antigen receptor and use thereof. The present invention provides a novel chimeric antigen receptor, comprising an extracellular domain, a transmembrane domain and an intracellular domain, wherein the transmembrane domain and the intracellular domain of the chimeric antigen receptor form a costimulatory signaling domain, and the costimulatory signaling domain comprises a full length or a fragment of an amino acid sequence encoding a reverse dectin-1. Experiments prove that novel CAR-T cells provided by the present invention are effective against a variety of solid tumors and hematological malignancies.