Abstract: Image enhancement is provided for medical diagnostic ultrasound. Knowledge-based detection of anatomy or artifact identifies locations to be enhanced. The knowledge-based detection of the locations may avoid identification of other anatomy or artifacts. The image enhancement is applied to the identified locations and not others.

Abstract: A system includes a scanner configured to generate scan data of a patient volume or area, a processor configured to implement control operations, the control operations being directed to acquisition of the scan data or to processing of the scan data, and a monitoring system including a range imaging camera positioned for a field of view such that the monitoring system is configured to capture spatial data indicative of movement of an object spaced from the scanner. The processor is configured to implement an adjustment in the control operations based on the spatial data.

Abstract: A positron emission tomography (PET) detector configuration for a combined PET and computed tomography (CT) imaging system, wherein the CT system includes an annular cavity. The configuration includes a backplane having a neutral axis and an aperture. In addition, the configuration includes at least one PET detector located about the aperture, wherein a center of mass of the at least one PET detector is in-line with the neutral axis and wherein a portion of the at least one PET detector is located in the annular cavity thereby reducing a footprint of the combined PET and CT imaging system. Further, the location of the at least one PET detector reduces the strength needed for maintaining structural integrity of the backplane.

Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.

Abstract: A method for forming a contrast pulse sequence ultrasound image using a pulse width modulation scheme and an ultrasound system using the same are disclosed. The ultrasound system generates at least three kinds of mutually different pulses having a same amplitude, and sequentially transmits at least three kinds of transmission signals corresponding to the at least three kinds of mutually different pulses to an ultrasound transducer. The ultrasound transducer transmits at least three kinds of ultrasound signals to a target object by sequentially generating the at least three kinds of ultrasound signals based on the at least three kinds of transmission signals. The ultrasound transducer generates at least three kinds of reception signals by sequentially receiving at least three kinds of echo signals reflected from the target object. The ultrasound system forms a contrast pulse sequence ultrasound image by eliminating a linear component from the at least three kinds of reception signals.

Abstract: A system includes reception of an a electrical signal from a light sensor, determination of a first integral over a first number of samples of the electrical signal, determination of an estimated energy of a first pulse based on the first integral, where the electrical signal includes the first pulse and a second pulse, where a portion of the second pulse overlaps a portion of the first pulse, determination of a second integral over a second number of samples of the electrical signal, determination of a second estimated energy of the first pulse over the second number of samples, determination of a residual short integral based on the second integral and the second estimated energy, and determination of an estimated energy of the second pulse based on the residual short integral.

Abstract: In nuclear medical imaging, respiratory motion is corrected. Rather than pairwise estimation of motion from projection views, a sequence-based technique is used to jointly estimate parameters for a motion model across many projection views. In one approach, this sequence-based method is iteratively solved with a maximum likelihood objective function incorporating the motion model. A surrogate respiration signal is used to gate for the joint estimation and used to convert gated motion parameters to temporal motion parameters.

Abstract: Motion artifacts are suppressed for three-dimensional parametric ultrasound imaging. Motion tracking is performed so that the parameter values derived over time are based on return from the same locations. Distortion due to the scan pattern is accounted for in the results of the motion tracking, such as by re-sampling the results to deal with discontinuity in time between data from adjacent sub-volumes and/or by aligning the scan pattern based on a direction of motion.

Abstract: By way of introduction, the present embodiments described below include apparatuses and methods for generating natural language representations of mental content from functional brain images. Given functional imaging data acquired while a subject reads a text passage, a reconstruction of the text passage is produced. Linguistic semantic vector representations are assigned (1301) to words, phrases or sentences to be used as training stimuli. Basis learning is performed (1305), using brain imaging data acquired (1303) when a subject is exposed to the training stimuli and the corresponding semantic vectors for training stimuli, to learn an image basis directly. Semantic vector decoding (1309) is performed with functional brain imaging data for test stimuli and using the image basis to generate a semantic vector representing the test imaging stimuli. Text generation (1311) is then performed using the decoded semantic vector representing the test imaging stimuli.

Abstract: Embodiments can provide a medical imaging patient bed with an integrated electronic ruler system, comprising a light strip, mounted to the medical imaging bed; a trough comprising an open end and a closed end, mounted to the medical imaging bed and oriented such that the light strip is bounded by the open end and the closed end of the trough; a laser distance meter attached to the open end of the trough; a microcontroller; and a power source configured to provide power to the light strip, laser distance meter, and microcontroller; wherein the microcontroller is configured to illuminate the light strip after one or more distance measurements are received from the laser distance meter when an object is inserted into the trough; wherein a position of the illumination of the light strip corresponds to the one or more distance measurements received from the laser distance meter.

Abstract: A method for self-time alignment procedure for a PET scanner system is disclosed. Modeled time-of-flight (TOF) data are compared against the measured TOF data in order to find individual detector's time offsets (TOs). Then the TOs are estimated simultaneously by matching the TOF center of mass between the modeled and measured TOF data.

Abstract: A volume of interest is ultrasonically imaged. An object of interest is automatically located from a volume scan. In one approach, a geometric bounding box surrounding the object is found by a classifier. In another approach, an option for zooming to the object is indicated to the user. A scan region is defined around the object or the bounding box automatically, whether in response to user selection of the option or not. The scan region is shaped based on the ultrasound scan format, but is smaller than the volume. The volume of interest defined by the scan region is used to generate images with a greater temporal and/or spatial resolution than scanning of the entire original volume.

Abstract: A detector of a gamma camera is configured such that a radioactive point source is positioned within a field of view at a fixed distance from the detector. A predetermined number of gamma photons emitted by the point source and passed through a collimator are acquired. A system-specific planar sensitivity is computed for a combination of the collimator and detector using the number of gamma photons acquired, a time duration of the acquisition, and precalibrated radioactivity data of the point source corrected for decay that occurred after a precalibration time. A deviation of the computed system-specific planar sensitivity from a class standard sensitivity value for a combination of the radioactive point source, the collimator, and the detector is computed. A class standard sensitivity value for a combination of a radiopharmaceutical, the collimator, and the detector is scaled by the computed deviation, yielding a scaled system-specific sensitivity value for the radiopharmaceutical.

Abstract: The present application is directed to radiolabeled imaging agents comprising a radiolabel, and a substrate, pharmaceutical compositions comprising radiolabeled imaging agents, and methods of using the radiolabeled imaging agents. The present application is further directed to methods of preparing the radiolabeled imaging agent. Such imaging agents can used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).

Abstract: A method and system for determining a radiopharmaceutical compound in a medical image is disclosed. In one embodiment, the method includes obtaining the medical image from a medical imaging device through an interface. The method also includes identifying a region of interest in the medical image. The method further includes generating a feature vector associable with the region of interest. Additionally, the method includes detecting an uptake of the radiopharmaceutical compound in the region of interest. Furthermore, the method includes identifying a type of the radiopharmaceutical compound in the region of interest based on the feature vector and a biological information associated with the region of interest.

Abstract: In spectral pulsed wave Doppler imaging, spatial variance in signal and/or noise are reduced by combination of multiple spectra with at least partially decorrelated noise. Rather than requiring oversampling in time, the multiple spectra for one Doppler gate are created from different spatial signals. The Doppler gate is divided into sub-gates, the beamformed sample locations in the Doppler gate are grouped into two or more groups using any selection criterion, and/or different receive apertures are used to simultaneously sample the Doppler gate. Spectra for the gate are estimated from the samples with the different spatial content and then combined.

Abstract: For sound speed imaging, different receive apertures are used instead of multiple transmissions from different angles. Acoustic echoes from a same transmission are receive beamformed with different apertures of the transducer array. The axial shift between the beamformed signals from the different apertures is used to solve for the speed of sound at one or more locations. The resulting measure of the speed of sound is displayed as the speed of sound in the tissue and may be diagnostically or prognostically useful.

Abstract: Anatomic range planning is provided in positron emission tomography (PET). The user indicates one or more ranges on an image of a patient based on anatomy. Rather than planning by bed position, the planning is based on the anatomy of the patient without reference to the length of the PET detector. The user interface for PET examination avoids overlapping boxes and other confusion based on bed position. Different anatomical ranges may be assigned different PET parameters, such as reconstruction parameters. A processor may automatically alter the examination (e.g., by extending the detection range beyond the region of interest or by increasing duration at an end position) to account for the sensitivity profile since the anatomical region of interest is known. Anatomical region specific directions may be included as part of planning, aiding in performing different protocols for different anatomical ranges.

Abstract: A method of growing a rare-earth oxyorthosilicate crystal, and crystals grown using the method are disclosed. The method includes preparing a melt by melting a first substance including at least one first rare-earth element and providing an atmosphere that includes an inert gas and a gas including oxygen.

Abstract: For a multi-modal emission tomography system, an improved control system increases the likelihood of optimal image quality, satisfaction of physician goals, and/or avoids repetition in scanning and the corresponding increase in dose burden. The control system is divided into two or more arrangements. One arrangement receives goal information and outputs reconstruction settings and generic scan settings to satisfy the goal information. Another arrangement converts the generic scan settings to emission tomography system-specific scan settings, which are used to detect emissions. The separation of the arrangements allows independent operation so that different system-specific conversions may be used for different systems.