Patents Assigned to Simes
  • Patent number: 5013753
    Abstract: Compounds of formula ##STR1## (wherein R, R.sub.1, R.sub.2 and X have the meanings reported in the specification), the processes for their preparation and the pharmaceutical compositions containing them as active ingredient are described.The compounds of formula I are useful in the treatment of Parkinson's disease, renal failure, cardiac decompensation and hypertension.
    Type: Grant
    Filed: July 28, 1989
    Date of Patent: May 7, 1991
    Assignee: Simes
    Inventors: Cesare Casagrande, Francesco Santangelo
  • Patent number: 4988735
    Abstract: The compound N,N'-dimethyl-N-(3,4,5-trimethoxybenzyl)-N'-[3,3-di-(4-fluorophenyl)-propy l]-ethylenediamine and its salts are described.This compound is useful in the treatment of several cardiovascular pathologies.
    Type: Grant
    Filed: May 24, 1988
    Date of Patent: January 29, 1991
    Assignee: Simes
    Inventors: Cesare Casagrande, Francesco Santangelo, Maria L. Calabi
  • Patent number: 4507307
    Abstract: N.sub.1 -acyl-3-amino-1,2,3,4-tetrahydroquinoline compounds active on the cardiocirculatory system, pharmaceutically acceptable salts thereof, pharmaceutical compositions containing the new compounds and some intermediates useful in the preparation of the new tetrahydroquinoline compounds.Process for preparing the new tetrahydroquinoline compounds and some intermediates useful in the preparation thereof.
    Type: Grant
    Filed: July 28, 1982
    Date of Patent: March 26, 1985
    Assignee: Simes
    Inventors: Vittorio Vecchietti, Emilio Mussini, Giorgio Ferrari