Abstract: Topically applicable pharmaceutical/dermatological/cosmetic compositions well suited for the therapeutic treatment or care of sensitive human skin, hair, mucous membranes, nails and/or the scalp, in particular for reducing or avoiding the skin-irritant side effects of a variety of bioactive agents, for example the .alpha.-hydroxy acids, comprise a therapeutically/cosmetically effective amount of at least one calcitonin gene related peptide ("CGRP") antagonist, e.g., CGRP 8-37 or an anti-CGRP antibody.
Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting effective amount of a novel sulfonamido-functional polyorganosiloxane/polyorganosilane having one of the formulae (1) to (3): ##STR1## wherein A is a monovalent benzylidenecamphor radical which comprises a sulfonamido-functional bridging group, which is bonded directly to a silicon atom, and which has the formula. (4.
Abstract: Methods and compositions for inducing or stimulating the growth of body or cranial hair using a peptide which comprises the Lysine-Proline-Valine sequence are described.
Abstract: The invention relates to the use of a histamine antagonist, an interleukin-1-antagonist and/or a TNF antagonist in a cosmetic, pharmaceutical or dermatological composition for treating sensitive skins. It relates especially to the use of a histamine antagonist, an interleukin-1 antagonist and/or a TNF alpha antagonist for preventing and/or combating skin irritations and/or sores and/or erythema and/or dysaesthetic sensations and/or sensations of inflammation and/or pruritus and/or prickling and/or tingling and/or discomfort and/or tightness of the skin and/or mucosae. It also relates to a composition containing a histamine antagonist, an interleukin-1 antagonist and/or a TNF alpha antagonist which limits or eliminates the irritant side-effects of certain products, and in particular of certain cosmetic, dermatological or pharmaceutical active agents.
Type:
Grant
Filed:
June 20, 1997
Date of Patent:
November 30, 1999
Assignee:
Societe L'Oreal S.A.
Inventors:
Olivier De Lacharriere, Lionel Breton, Catherine Cohen
Abstract: Topically applicable, stable, photoprotective cosmetic/dermatological compositions, well suited for improved photoprotection of human skin and/or hair against the damaging effects of UV irradiation, particularly solar radiation, comprise (a) an effective photoprotecting amount of at least one dibenzoylmethane compound and (b) an effective photostabilizing amount of at least one polysaccharide alkyl ether.
Abstract: The present invention relates to the use of 2-ethylhexyl .alpha.-cyano-.beta.,.beta.-diphenylacrylate in, or for the manufacture of, cosmetic compositions containing p-methylbenzylidenecamphor in combination with at least one dibenzoylmethane derivative, for the purpose of improving the stability of p-methylbenzylidenecamphor in such compositions.
Abstract: Topically applicable dermocosmetic compositions for improving or maintaining the appearance of human skin or the scalp, comprise a minor antioxidant effective amount of melatonin or analog thereof, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor, such minor antioxidant effective amount being less than 10.sup.-4 % by weight relative to the total weight thereof, e.g., no greater than 0.5.times.10.sup.-4 % or ranging from 10.sup.-12 % to 10.sup.-15 % by weight thereof.
Type:
Grant
Filed:
July 25, 1997
Date of Patent:
November 16, 1999
Assignee:
Societe L'oreal S.A.
Inventors:
Pierre Tachon, Francis Pruche, Catherine Gerst, Jean-Fran.cedilla.ois Nadaud, Lionel Breton
Abstract: Novel cosmetic/dermatological UV-photoprotective compositions well suited for enhanced PF photoprotection of human skin and/or hair comprise (a) an effective UV-screening amount of at least one benzylidenecamphor sunscreen compound, and/or at least one dibenzoylmethane sunscreen compound, and/or at least one triazine sunscreen compound, and (b) a PF-enhancing amount of at least one dialkyl tartrate, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor.
Type:
Grant
Filed:
September 9, 1998
Date of Patent:
November 16, 1999
Assignee:
Societe L'Oreal S.A.
Inventors:
Martin Josso, Jean-Louis Refregier, Isabelle Hansenne
Abstract: Stable, topically applicable cosmetic/dermatological compositions well suited for artificially tanning or browning human skin and appropriately packaged, comprise at least one dihydroxyacetone (DHA) derivative convertible into DHA and, advantageously, at least one active species for effecting such conversion.
Type:
Grant
Filed:
March 18, 1997
Date of Patent:
October 26, 1999
Assignee:
Societe L'Oreal S.A.
Inventors:
Remy Tuloup, Christian Blaise, Michel Philippe, Daniel Sera, Armelle De Salvert
Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting synergistically effective amount of (i) 2,4,6-tris[p-((2'-ethylhexyl)oxycarbonyl)anilino]-1,3,5-triazine and (ii) 2-ethylhexyl .alpha.-cyano-.beta.,.beta.-diphenylacrylate, in a cosmetically acceptable vehicle, diluent or carrier therefor.
Abstract: The invention relates to the use of an ethylenediamine derivative as a substance P antagonist and/or as a local analgesic in, or for the preparation of, a cosmetic or dermatological composition for treating sensitive skin-types. The invention relates in particular to the use of this derivative for preventing and/or combating skin irritations and/or dartres and/or erythema and/or dysaesthesic sensations and/or sensations of inflammation and/or pruritus of the skin and/or the mucous membranes including the eyes. The invention also relates to a composition containing a product having an irritant side effect and this derivative, so as to reduce this irritant effect or even to remove it altogether.
Type:
Grant
Filed:
November 24, 1997
Date of Patent:
October 19, 1999
Assignee:
Societe L'Oreal S.A.
Inventors:
Oliver De Lacharriere, Jean-Baptiste Galey, Lionel Breton, Jacqueline Dumats
Abstract: Transfer-resistant cosmetic/dermatological compositions (e.g., lipcolors) formulated as supple and homogeneous doughs, advantageously via extrusion, include a fatty phase which comprises at least one volatile oil, at least one phenylated silicone oil and at least 12% by weight of at least one wax.
Type:
Grant
Filed:
February 26, 1998
Date of Patent:
October 12, 1999
Assignee:
Societe L'Oreal S.A.
Inventors:
Isabelle Agostini, Dolores Miguel-Colombel, Fran.cedilla.ois Pradier, Alex Junino, Veronique Le Bras-Roulier
Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting effective amount of a novel cinnamonitrile-substituted polyorganosiloxane/polyorganosilane.
Abstract: A regimen for inducing/stimulating hair growth and/or retarding hair loss on an individual in need of such treatment, comprising administering thereto, advantageously topically and for such period of time as required to elicit the desired effect, an effective amount of at least one RXR-type retinoid receptor agonist preferably having the structural formula(I): ##STR1## in which Ar is one of the following radicals: ##STR2##
Type:
Grant
Filed:
September 9, 1997
Date of Patent:
October 5, 1999
Assignee:
Societe L'Oreal S.A.
Inventors:
Nelly Billoni, Yann Mahe, Bruno Bernard
Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting effective amount of a novel benzotriazole-substituted polyorganosiloxane/polyorganosilane having one of the formulae (1) to (3): ##STR1## wherein A is a monovalent benzotriazole radical bonded directly to a silicon atom and having the formula (4): ##STR2## the compounds of formulae (1) to (3) are prepared, e.g.
Abstract: Cosmetic/pharmaceutical compositions, well suited for the treatment of a variety of mammalian disorders of, for example, the skin, hair and/or mucous membranes, a manifestation of which is an excess in the synthesis and/or in the release of substance P, e.g., for the treatment of cutaneous disorders and sensitive skin, comprise an effective substance P antagonist amount of at least one .beta.-adrenergic agonist, e.g., salbutamol, in a cosmetically/pharmaceutically acceptable medium therefor.
Type:
Grant
Filed:
October 23, 1996
Date of Patent:
September 28, 1999
Assignee:
Societe L'Oreal S.A.
Inventors:
Lionel Breton, Olivier de Lacharriere, Jacques Leclaire
Abstract: Novel 4,4-dihydroxy-5-pyrazolinones having the structural formula (I): ##STR1## and cosmetic/dermatological formulations comprised thereof are useful for artificially coloring, e.g., tanning/browning, human skin and/or hair, and are well suited for imparting a healthy appearance to facial skin by enhancing the radiance of the complexion, while at the same time retaining transparency.
Abstract: Topically applicable cosmetic/sunscreen/dermatological compositions, well suited for improved photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation and/or for the therapeutic treatment of a disease state of the skin or mucosae, essentially in the absence of photobluing/whitening, comprise at least one titanium dioxide (nano)pigment and an effective photobluing/whitening-reducing amount of deformable hollow particulates (microspheres) having a particle size ranging from 1 .mu.m to 250 .mu.m and which comprise an expanded copolymer of vinylidene chloride, acrylonitrile and a (meth)acrylate.
Abstract: Topically applicable, stable, UV-photoprotective cosmetic/dermatological compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, comprise (a) an effective UV-photoprotecting amount of at least one dibenzoylmethane UV-sunscreen compound and (b) an effective dibenzoylmethane compound (a) photostabilizing amount of at least one benzalmalonate silane having the structural formula (I): ##STR1##
Abstract: Stable, recrystallization-resistant dermatological/cosmetic compositions, well suited for preventing/treating oxidative stress of the skin, comprise a substantially ethanol-free aqueous phase, the aqueous phase containing an active amount of solubilized melatonin values and an amount of at least one glycol effective to dissolve such melatonin values.